Leptin and leptin receptor expression in asthma

Journal of Allergy and Clinical Immunology

Volumn 124, Issue 2, 2009, Pages

  Bruno, Andreina ^a   Pace, Elisabetta ^a   Chanez, Pascal ^b   Gras, Delphine ^b   Vachier, Isabelle ^c   Chiappara, Giuseppina ^a   La Guardia, Maurizio ^d   Gerbino, Stefania ^a,d   Profita, Mirella ^a   Gjomarkaj, Mark ^a  

^a CNR Consiglio Nazionale delle Ricerche   (Italy)

^b ASSISTANCE PUBLIQUE HÔPITAUX DE MARSEILLE   (France)

^c MONTPELLIER UNIVERSITY HOSPITAL   (France)

^d UNIVERSITY OF PALERMO   (Italy)

Author keywords

epithelium; Leptin; leptin receptor; remodeling; severe asthma; TGF

Indexed keywords

CORTICOSTEROID; FLUTICASONE PROPIONATE; LEPTIN; LEPTIN RECEPTOR; PREDNISONE; TRANSFORMING GROWTH FACTOR BETA;

ADULT; ARTICLE; ASTHMA; BASEMENT MEMBRANE; BRONCHUS MUCOSA; CELL PROLIFERATION; CHRONICITY; CLINICAL ARTICLE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DISEASE SEVERITY; EPITHELIUM CELL; EX VIVO STUDY; FEMALE; FIBEROPTIC BRONCHOSCOPY; FLOW CYTOMETRY; FORCED EXPIRATORY VOLUME; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LUNG BIOPSY; MALE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 67849121303     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2009.04.032     Document Type: Article

References (38)

1. Matarese G., Mantzoros C., and La Cava A. Leptin and adipocytokines: bridging the gap between immunity and atherosclerosis. Curr Pharm Des 13 (2007) 3676-3680
2. Conus S., Bruno A., and Simon H.U. Leptin is an eosinophil survival factor. J Allergy Clin Immunol 116 (2005) 1228-1234
3. Bruno A., Conus S., Schimd I., and Simon H.U. Apoptotic pathways are inhibited by leptin receptor activation in neutrophils. J Immunol 174 (2005) 8090-8096
4. Bruno A., Chanez P., Chiappara G., Siena L., Giammanco S., Gjomarkaj M., et al. Does leptin play a cytokine-like role within the airways of COPD patients?. Eur Respir J 26 (2005) 398-405
5. Goren I., Kämpfer H., Podda M., Pfeilschifter J., and Frank S. Leptin and wound inflammation in diabetic ob/ob mice: differential regulation of neutrophil and macrophage influx and a potential role for the scab as a sink for inflammatory cells and mediators. Diabetes 52 (2003) 2821-2832
6. Bergen H.T., Cherlet T.C., Manuel P., and Scott J.E. Identification of leptin receptors in lung and isolated fetal type II cells. Am J Respir Cell Mol Biol 27 (2002) 71-77
7. Wolk R., Deb A., Caplice N.M., and Somers V.K. Leptin receptor and functional effects of leptin in human endothelial progenitor cells. Atherosclerosis 183 (2005) 131-139
8. Shore S.A., Schwartzman I.M., Mellema M.S., Flynt L., Imrich A., and Johnston R.A. Effect of leptin on allergic airway responses in mice. J Allergy Clin Immunol 115 (2005) 103-109
9. Burgel P.R., and Nadel J.A. Epidermal growth factor receptor-mediated innate immune responses and their roles in airway diseases. Eur Respir J 32 (2008) 1068-1081
10. James A.L., and Wenzel S. Clinical relevance of airway remodelling in airway diseases. Eur Respir J 30 (2007) 134-155
11. Jeffery P.K. Remodelling in asthma and chronic obstructive lung disease. Am J Respir Crit Care Med 164 suppl (2001) S28-S38
12. Holgate S.T., Peters-Golden M., Panettieri R.A., and Henderson Jr. W.R. Roles of cysteinyl leukotrienes in airway inflammation, smooth muscle function, and remodelling. J Allergy Clin Immunol 111 suppl (2003) S18-S34
13. Roberts C.R. Is asthma a fibrotic disease?. Chest 107 suppl (1995) 111s-117s
14. Vignola A.M., Kips J., and Bousquet J. Tissue remodelling as a feature of persistent asthma. J Allergy Clin Immunol 105 (2000) 1041-1053
15. Vignola A.M., Chanez P., Chiappara G., Merendino A., Pace E., Rizzo A., et al. Transforming growth factor-β expression in mucosal biopsies in asthma and chronic bronchitis. Am J Respir Crit Care Med 156 (1997) 591-599
16. Profita M., Gagliardo R., Di Giorgi R., Bruno A., Riccobono L., Bonanno A., et al. In vitro effects of flunisolide on MMP-9, TIMP-1, fibronectin, TGF-beta1 release and apoptosis in sputum cells freshly isolated from mild to moderate asthmatics. Allergy 59 (2004) 927-932
17. Chanez P. Severe asthma is an epithelial disease. Eur Respir J 25 (2005) 945-946
18. Chanez P., Wenzel S.E., Anderson G.P., Anto J.M., Bel E.H., Boulet L.P., et al. Severe asthma in adults: what are the important questions?. J Allergy Clin Immunol 119 (2007) 1337-1348
19. Chen X.L., Hausman D.B., Dean R.G., and Hausman G.J. Hormonal regulation of leptin mRNA expression and preadipocyte recruitment and differentiation in porcine primary cultures of S-V cells. Obes Res 6 (1998) 164-172
20. Lee M.J., Wang Y., Ricci M.R., Sullivan S., Russell C.D., and Fried S.K. Acute and chronic regulation of leptin synthesis, storage, and secretion by insulin and dexamethasone in human adipose tissue. Am J Physiol Endocrinol Metab 292 (2007) E858-E864
21. Wyrwoll C.S., Mark P.J., and Waddell B.J. Directional secretion and transport of leptin and expression of leptin receptor isoforms in human placental BeWo cells. Mol Cell Endocrinol 241 (2005) 73-79
22. Cozens A.L., Yezzi M.J., Kunzelmann K., Ohrui T., Chin L., Eng K., et al. CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells. Am J Respir Cell Mol Biol 10 (1994) 38-47
23. Global Initiative for Asthma (GINA). Available at: www.ginasthma.org. Accessed 2008.
24. Juniper E.F., O'Byrne P.M., Guyatt G.H., Ferrie P.J., and King D.R. Development and validation of a questionnaire to measure asthma control. Eur Respir J 14 (1999) 902-907
25. Pauwels R.A., Löfdahl C.G., Postma D.S., Tattersfield A.E., O'Byrne P., Barnes P.J., et al. Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group. N Engl J Med 337 (1997) 1405-1411
26. Chanez P., Vignola A.M., Vic P., Guddo F., Bonsignore G., Godard P., et al. Comparison between nasal and bronchial inflammation in asthmatic and control subjects. Am J Respir Crit Care Med 159 (1999) 588-595
27. Hansen G.H., Niels-Christiansen L.L., and Danielsen E.M. Leptin and the obesity receptor (OB-R) in the small intestine and colon: a colocalization study. J Histochem Cytochem 56 (2008) 677-685
28. Feuermann Y., Mabjeesh S.J., Niv-Spector L., Levin D., and Shamay A. Prolactin affects leptin action in the bovine mammary gland via the mammary fat pad. J Endocrinol 191 (2006) 407-413
29. Fixman E.D., Stewart A., and Martin J.G. Basic mechanisms of development of airway structural changes in asthma. Eur Respir J 29 (2007) 379-389
30. Holgate S.T. The airway epithelium is central to the pathogenesis of asthma. Allergol Int 57 (2008) 1-10
31. Bourdin A., Neveu D., Vachier I., Paganin F., Godard P., and Chanez P. Specificity of basement membrane thickening in severe asthma. J Allergy Clin Immunol 119 (2007) 1367-1374
32. Willis B.C., Liebler J.M., Luby-Phelps K., Nicholson A.G., Crandall E.D., du Bois R.M., et al. Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta 1: potential role in idiopathic pulmonary fibrosis. Am J Pathol 166 (2005) 1321-1332
33. Balzar S., Chu H.W., Silkoff P., Cundall M., Trudeau J.B., Strand M., et al. Increased TGF-beta2 in severe asthma with eosinophilia. J Allergy Clin Immunol 115 (2005) 110-117
34. Wenzel S.E., Balzar S., Cundall M., and Chu H.W. Subepithelial basement membrane immunoreactivity for matrix metalloproteinase 9: association with asthma severity, neutrophilic inflammation, and wound repair. J Allergy Clin Immunol 111 (2003) 1345-1352
35. Holgate S.T. Epithelial dysfunction in asthma. J Allergy Clin Immunol 120 (2007) 1233-1244
36. Knight D.A., and Holgate S.T. The airway epithelium: structural and functional properties in health and disease. Respirology 8 (2003) 432-446
37. Torday J.S., Sun H., Wang L., Torres E., Sunday M.E., and Rubin L.P. Leptin mediates the parathyroid hormone-related protein paracrine stimulation of fetal lung maturation. Am J Physiol Lung Cell Mol Physiol 282 (2002) L405-L410
38. Karjalainen E.M., Lindqvist A., Laitinen L.A., Kava T., Altraja A., Halme M., et al. Airway inflammation and basement membrane tenascin in newly diagnosed atopic and nonatopic asthma. Respir Med 97 (2003) 1045-1051