Apigenin induces caspase-dependent apoptosis in human lung cancer A549 cells through Bax- And Bcl-2-triggered mitochondrial pathway

International Journal of Oncology

Volumn 36, Issue 6, 2010, Pages 1477-1484

  Lu, Hsu Feng ^a,b   Chie, Y U Jie ^d   Yang, Ming Sung ^a   Lee, Ching Sung ^b   Fu, Jene John ^c   Yang, Jai Sing ^d   Tan, Tzu Wei ^d   Wu, Shin Hwar ^d,e   Ma, Y I Shih ^d   Ip, Siu Wan ^d   Chung, Jing Gung ^d,f  

^a CHENG HSIN GENERAL HOSPITAL   (Taiwan)

^b FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^c Landseed Hospital   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

^e Division of Critical Care Medicine   (Taiwan)

^f ASIA UNIVERSITY   (Taiwan)

Author keywords

A549 lung cancer cells; Apigenin; Apoptosis; Bax protein; Caspases

Indexed keywords

APIGENIN; CALCIUM ION; CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL FUNCTION; CELL STRUCTURE; CELL VIABILITY; CLINICAL PATHWAY; DNA DAMAGE; HUMAN; HUMAN CELL; LUNG CANCER; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION;

ANTINEOPLASTIC AGENTS; APIGENIN; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SEPARATION; COMET ASSAY; DNA DAMAGE; FLOW CYTOMETRY; HUMANS; LUNG NEOPLASMS; MICROSCOPY, CONFOCAL; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION;

EID: 77951564322     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000634     Document Type: Article

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