Perspectives in MicroRNA therapeutics

Pharmaceutical Technology

Volumn 35, Issue 5 SUPPL. 1, 2011, Pages

  Steffy, Kevin ^a   Allerson, Charles ^a   Bhat, Balkrishen ^a  

^a REGULUS THERAPEUTICS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEEP PIPELINES; DRUG DISCOVERY; MICRORNAS; RESEARCH AND DEVELOPMENT;

DRUG DELIVERY; OLIGONUCLEOTIDES;

GENE EXPRESSION;

ANTISENSE OLIGONUCLEOTIDE; MICRORNA; SMALL INTERFERING RNA;

ARTICLE; DRUG RESEARCH; GENE TARGETING; GENE TECHNOLOGY; HUMAN; RNA ANALYSIS; RNA INTERFERENCE;

EID: 80051906974     PISSN: 15432521     EISSN: 21507376     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. S.T. Crooke et al., "Mechanisms of Antisense Drug Action, an Introduction, " in Antisense Drug Technology: Principles, Strategies, and Applications, S.T. Crooke, Ed. (CRC Press, Boca Raton, 2007), pp. 3-47.
2. S.M. Elbashir et al., Nature 411 (6386), 494-498 (2001).
3. A. Jackson and P.S. Linsley, Discovery Medicine 9 (47), 311-318 (2010).
4. J. Krutzfeldt et al., Nature 438 (7068), 685-689 (2005).
5. D.P. Bartel, Cell 116 (2), 281-297 (2004).
6. E.C. Lai, Nat. Rev. Genet 30 (4), 363-364 (2002).
7. T. Thum et al., Nature 456 (7224), 980-984 (2008).
8. L. Ma et al., Nature 28 (4), 341-347 (2010).
9. R.E. Lanford et al., Science 327 (5962), 198-201 (2010).
10. P.P. Seth et al., J. Med. Chem. 52 (1), 10-13 (2009).
11. A.A. Levin, R. Zu, and R.S. Geary, "Basic Principles of the Pharmacokinetics of Antisense Oligonucleotide Drugs, " in Antisense Drug Technology: Principles, Strategies, and Applications, S.T. Crooke, Ed. (CRC Press, Boca Raton, 2007), pp. 183-215.
12. B. Monia et al. J. Biol. Chem. 268 (19), 14514-14522 (1993).
13. R.S. Geary, R. Zu, and A.A. Levin, "Pharmacokinetic/Pharmacodynamic Properties of Phosphorothioate 2'-O-(2-Methoxyethyl)-Modified Antisense Oligonucleotides in Animals and Man, " in Antisense Drug Technology: Principles, Strategies, and Applications, S.T. Crooke, Ed. (CRC Press, Boca Raton, 2007), pp. 306-326.
14. S.C. Semple et al., Nature Biotech. 28 (2), 172-176 (2010).
15. S.V. Dongen et al., Nature Methods 5 (12) 1023-1025 (2008). PT