Cationic nanoemulsion as a delivery system for oligonucleotides targeting malarial topoisomerase II

International Journal of Pharmaceutics

Volumn 416, Issue 2, 2011, Pages 402-409

  Bruxel, F ^a,b   Cojean, S ^a   Bochot, A ^a   Teixeira, H ^b   Bories, C ^a   Loiseau, P M ^a   Fattal, E ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Cationic nanoemulsion; DOTAP; Oligonucleotides; Plasmodium falciparum; Topoisomerase II

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; ANTISENSE OLIGONUCLEOTIDE; CHLOROQUINE; DNA TOPOISOMERASE (ATP HYDROLYSING); MEDIUM CHAIN TRIACYLGLYCEROL; NANOCARRIER; PHOSPHATIDYLCHOLINE; PHOSPHOROTHIOIC ACID DERIVATIVE; WATER;

ADSORPTION; ANTIMALARIAL ACTIVITY; ANTISENSE THERAPY; ARTICLE; COMPLEX FORMATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CULTURE MEDIUM; DRUG DETERMINATION; DRUG STABILITY; ELECTRICITY; ERYTHROCYTE; GROWTH INHIBITION; HEMOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LIFE CYCLE; NANOEMULSION; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; NORMAL HUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

ANTIMALARIALS; CATIONS; DNA TOPOISOMERASES, TYPE II; DRUG DELIVERY SYSTEMS; DRUG STABILITY; EMULSIONS; ERYTHROCYTES; HEMOLYSIS; HUMANS; NANOPARTICLES; OLIGONUCLEOTIDES, ANTISENSE; PHOSPHOROTHIOATE OLIGONUCLEOTIDES; PLASMODIUM FALCIPARUM;

EID: 80051899117     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.01.048     Document Type: Article

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