Cationic vectors in ocular drug delivery

Journal of Drug Targeting

Volumn 12, Issue 9-10, 2004, Pages 623-633

  Rabinovich Guilatt, Laura ^a,b,c   Couvreur, Patrick ^a   Lambert, Gregory ^b   Dubernet, Catherine ^a  

^a UNIV PARIS SUD   (France)

^b Novagali Pharma   (France)

^c UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

Cationic colloids; Emulsions; Liposomes; Nanoparticles; Ocular drug delivery; Ophthalmic dosage forms

Indexed keywords

ACETAZOLAMIDE; ACICLOVIR; AGENTS ACTING ON THE EYE; ATROPINE; CARBON 14; CYCLOSPORIN; DRUG CARRIER; INDOMETACIN; LIPOSOME; NANOPARTICLE; PENICILLIN G; PHOSPHATIDYLCHOLINE; POLYCAPROLACTONE; RHODAMINE; TROPICAMIDE;

BLEPHARITIS; COLLOID; CONJUNCTIVITIS; CONTROLLED STUDY; CORNEA PERMEABILITY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG ELIMINATION; DRUG FORMULATION; DRUG PENETRATION; EMULSION; ENCAPSULATION; ENDOCYTOSIS; HUMAN; HUMAN TISSUE; INTRAOCULAR PRESSURE; IONIC STRENGTH; KERATOCONJUNCTIVITIS SICCA; LACRIMAL FLUID; NONHUMAN; PH; PHYSICOCHEMICAL MODEL; PRIORITY JOURNAL; REVIEW;

ANIMALS; CATIONS; CORNEA; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; EMULSIONS; HUMANS; LIPOSOMES; NANOSTRUCTURES; PERMEABILITY;

EID: 11944267744     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/10611860400015910     Document Type: Review

References (64)

1. Abdulrazik, M., Tamilvanan, S., Khoury, K. and Benita, S. (2001) "Ocular delivery of cyclosporin A. II. Effect of submicron emulsion's surface charge on ocular distribution of topical cyclosporin A", STP Pharma Sci. 11, 427-432.
2. Ahmed, I. and Patton, T.F. (1984) "Effect of pH and buffer on the precorneal disposition and ocular penetration of pilocarpine in rabbits", Int. J. Pharm. 19, 215-227.
3. Ahmed, I. and Patton, T.F. (1985) "Importance of the noncorneal absorption route in topical ophthalmic drug delivery", Investig. Ophthalmol. Vis. Sci. 26, 584-587.
4. Ahmed, I., Gokhale, R.D., Shah, M.V. and Patton, T.F. (1987) "Physicochemical determinants of drug diffusion across the conjunctiva, sclera, and cornea", J. Pharm. Sci. 76, 583-586.
5. Almofti, M.R., Harashima, H., Shinohara, Y., Almofti, A., Baba, Y. and Kiwada, H. (2003) "Cationic liposome-mediated gene delivery: biophysical study and mechanism of internalization", Arch. Biochem. Biophys. 410, 246-253.
6. Ashton, P., Podder, S.K. and Lee, V.H. (1991) "Formulation influence on conjunctival penetration of four beta blockers in the pigmented rabbit: a comparison with corneal penetration", Pharm. Res. 8, 1166-1174.
7. Baeyens, V. and Gurny, R. (1997) "Chemical and physical parameters of tears relevant for the design of ocular drug delivery formulations", Pharm. Acta Helv. 72, 191-202.
8. Behrens, I., Pena, A.I., Alonso, M.J. and Kissel, T. (2002) "Comparative uptake studies of bioadhesive and non-bioadhesive nanoparticles in human intestinal cell lines and rats: the effect of mucus on particle adsorption and transport", Pharm. Res. 19, 1185-1193.
9. Calvo, P., Thomas, C., Alonso, M.J., Vila-Jato, J.L. and Robinson, J.R. (1994) "Study of the mechanism of interaction of poly(e-caprolactone) nanocapsules with the cornea by confocal laser scanning microscopy", Int. J. Pharm. 55, 283-291.
10. Calvo, P., Alonso, M.J., Vila-Jato, J.L. and Robinson, J.R. (1996a) "Improved ocular bioavailability of indomethacin by novel ocular drug carriers", J. Pharm. Pharmacol. 48, 1147-1152.
11. Calvo, P., Vila-Jato, J.L. and Alonso, M.J. (1996b) "Comparative in vitro evaluation of several colloidal systems, nanoparticles, nanocapsules, and nanoemulsions, as ocular drug carriers", J. Pharm. Sci. 85, 530-536.
12. Calvo, P., Vila-Jato, J.L. and Alonso, M.J. (1997) "Evaluation of cationic polymer-coated nanocapsules as ocular drug carriers", Int. J. Pharm. 153, 41-50.
13. Carney, L.G., Mauger, T.F. and Hill, R.M. (1989) "Buffering in human tears: pH responses to acid and base challenge", Investig. Ophthalmol. Vis. Sci. 30, 747-754.
14. Chien, D.S., Homsy, J.J., Gluchowski, C. and Tang-Liu, D.D. (1990) "Corneal and conjunctival/scleral penetration of p-aminoclonidine, AGN 190342, and clonidine in rabbit eyes", Curr. Eye Res. 9, 1051-1059.
15. Chrai, S.S., Patton, T.F., Mehta, A. and Robinson, J.R. (1973) "Lacrimal and instilled fluid dynamics in rabbit eyes", J. Pharm. Sci. 62, 1112-1121.
16. Conroy, C.W. and Maren, T.H. (1995) "Effect of pH on the ocular distribution of a topical carbonic anhydrase inhibitor", Exp. Eye Res. 61, 213-222.
17. da Cruz, M.T., Simoes, S., Pires, P.P., Nir, S. and de Lima, M.C. (2001) "Kinetic analysis of the initial steps involved in lipoplex-cell interactions: effect of various factors that influence transfection activity", Biochim. Biophys. Acta 1510, 136-151.
18. de Campos, A.M., Sanchez, A. and Alonso, M.J. (2001) "Chitosan nanoparticles: a new vehicle for the improvement of the delivery of drugs to the ocular surface. Application to cyclosporin A", Int. J. Pharm. 224, 159-168.
19. de Campos, A.M., Sanchez, A., Gref, R., Calvo, P. and Alonso, M.J. (2003) "The effect of a PEG versus a chitosan coating on the interaction of drug colloidal carriers with the ocular mucosa", Eur. J. Pharm. Sci. 20, 73-81.
20. Diebold, Y., Enriquez de Salamanca, A., Jarrin, M., Callejo, S., Vila, A. and Alonso, M.J. (2003) "Uptake of bioadhesive nanoparticles in a normal human conjunctiva (NHC) epithelial cell line", ARVO Meeting Abstracts 44, 3785.
21. 14C]acrylate nanoparticles in healthy and chronically inflamed rabbit eyes", Int. J. Pharm. 54, 149-153.
22. Ding, S. (1998) "Recent developments in ophthalmic drug delivery", Pharm. Sci. Technol. Today 1, 328-335.
23. Edward, A. and Prausnitz, M.R. (2001) "Predicted permeability of the cornea to topical drugs", Pharm. Res. 18 1497-1508.
24. El-Gazayerly, O.N and Hikal, A.H. (1997) "Preparation and evaluation of acetazolamide liposomes as an ocular delivery system", Int. J. Pharm. 158, 121-127.
25. Felt, O., Furrer, P., Mayer, J.M., Plazonnet, B., Buri, P. and Gurny, R. (1999) "Topical use of chitosan in ophthalmology: tolerance assessment and evaluation of precorneal retention", Int. J. Pharm. 180, 185-193.
26. Fitzgerald, P., Hadgraft, J. and Wilson, C.G. (1987) "A gamma scintigraphic evaluation of the precorneal residence of liposomal formulations in the rabbit", J. Pharm. Pharmacol. 39, 487-490.
27. Hamalainen, K.M., Kananen, K., Auriola, S., Kontturi, K. and Urtti, A. (1997) "Characterization of paracellular and aqueous penetration routes in cornea, conjunctiva, and sclera", Investig. Ophthalmol. Vis. Sci. 38, 627-634.
28. Hill, R.M. and Carney, L.G. (1980) "Human tear responses to alkali", Investig. Ophthalmol. Vis. Sci. 19, 207-210.
29. Huang, H.S., Schoenwald, R.D. and Lach, J.L. (1983) "Corneal penetration behavior of beta-blocking agents. II: assessment of barrier contributions", J. Pharm. Sci. 72, 1272-1279.
30. Huang, M., Ma, Z., Khor, E. and Lim, L.Y. (2002) "Uptake of FITC-chitosan nanoparticles by A549 cells", Pharm. Res. 19, 1488-1494.
31. Kaur, I.P., Garg, A., Singla, A.K. and Aggarwal, D. (2004) "Vesicular systems in ocular drug delivery: an overview", Int. J. Pharm. 269, 1-14.
32. Klang, S.H., Frucht-Pery, J., Hoffman, A. and Benita, S. (1994) "Physicochemical characterization and acute toxicity evaluation of a positively-charged submicron emulsion vehicle", J. Pharm. Pharmacol. 46, 986-993.
33. Klang, S.H., Siganos, C.S., Benita, S. and Frucht-Pery, J. (1999) "Evaluation of a positively charged submicron emulsion of piroxicam on the rabbit corneum healing process following alkali burn", J. Control. Release 57, 19-27.
34. Klang, S., Abdulrazik, M. and Benita, S. (2000) "Influence of emulsion droplet surface charge on indomethacin ocular tissue distribution", Pharm. Dev. Technol. 5, 521-532.
35. Law, S.L., Huang, K.J. and Chiang, C.H. (2000) "Acyclovir-containing liposomes for potential ocular delivery. Corneal penetration and absorption", J. Control. Release 63, 135-140.
36. Lehr, C.M., Bouwstra, J.A., Schacht, E.H. and Junginger, H.E. (1992) "In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers", Int. J. Pharm. 78, 43-48.
37. Liaw, J., Rojanasakul, Y. and Robinson, J.R. (1992) "The effect of drug charge type and charge density on corneal transport", Int. J. Pharm. 88, 111-124.
38. Longwell, A., Birss, S., Keller, N. and Moore, D. (1976) "Effect of topically applied pilocarpine on tear film pH", J. Pharm. Sci. 65, 1654-1657.
39. Maren, T.H. and Jankowska, L. (1985) "Ocular pharmacology of sulfonamides: the cornea as barrier and depot", Curr. Eye Res. 4, 399-408.
40. Meisner, D. and Mezer, M. (1995) "Liposome ocular delivery systems", Adv. Drug Deliv. Rev. 16, 75-93.
41. Meisner, D., Pringle, J. and Mezei, M. (1989) "Liposomal ophthalmic drug delivery. III. Pharmacodynamic and biodisposition studies of atropine", Int. J. Pharm. 55, 105-113.
42. Muchtar, S., Abdulrazik, M., Frucht-Pery, J. and Benita, S. (1997) "Ex-vivo permeation study of indomethacin from a submicron emulsion through albino rabbit cornea", J. Control. Release 44 55-64.
43. Nagarsenker, M.S., Londhe, V.Y. and Nadkarni, G.D. (1999) "Preparation and evaluation of liposomal formulations of tropicamide for ocular delivery", Int. J. Pharm. 190, 63-71.
44. Pandit, J.C., Nagyova, B., Bron, A.J. and Tiffany, J.M. (1999) "Physical properties of stimulated and unstimulated tears", Exp. Eye Res. 68, 247-253.
45. Patton, T.F. and Robinson, J.R. (1976) "Quantitative precorneal disposition of topically applied pilocarpine nitrate in rabbit eyes", J. Pharm. Sci. 65, 1295-1301.
46. Pignatello, R., Bucolo, C., Ferrara, P., Maltese, A., Puleo, A. and Puglisi, G. (2002a) "Eudragit RS100 nanosuspensions for the ophthalmic controlled delivery of ibuprofen", Eur. J. Pharm. Sci. 16, 53-61.
47. Pignatello, R., Bucolo, C., Spedalieri, G., Maltese, A. and Puglisi, G. (2002b) "Flurbiprofen-loaded acrylate polymer nanosuspensions for ophthalmic application", Biomaterials 23 3247-3255.
48. Qaddoumi, M.G., Gukasyan, H.J., Davda, J., Labhasetwar, V., Kim, K.J. and Lee, V.H. (2003) "Clathrin and caveolin-1 expression in primary pigmented rabbit conjunctival epithelial cells: role in PLGA nanoparticle endocytosis", Mol. Vis. 9, 559-568.
49. Rabinovich-Guilatt, L., Couvreur, P., Lambert, G., Goldstein, D., Benita, S. and Dubernet, C. (2004) "Extensive surface studies help to analyse zeta potential data: the case of cationic emulsions" , Chem. Phys. Lipids 131, 1-13.
50. Robinson, J.R. (1993) "Ocular anatomy and physiology relevant to ocular drug delivery", In: Mitra, A.K., ed., Ophthalmic Drug Delivery Systems (Marcel Dekker, New York), pp 29-57.
51. Rojanasakul, Y. and Robinson, J.R. (1989) "Transport mechanisms of the cornea: characterization of barrier permselectivity", Int. J. Pharm. 55, 237-246.
52. Schaeffer, H.E. and Krohn, D.L. (1982) "Liposomes in topical drug delivery", Investig. Ophthalmol. Vis. Sci. 22, 220-227.
53. Schoenwald, R.D. and Huang, H.S. (1983) "Corneal penetration behavior of beta-blocking agents I: Physiochemical factors", J. Pharm. Sci. 72, 1266-1272.
54. Schoenwald, R.D. and Ward, R.L. (1978) "Relationship between steroid permeability across excised rabbit cornea and octanol-water partition coefficients", J. Pharm. Sci. 67, 786-788.
55. Singh, M., Meisner, D., Faulkner, G. and Mezei, M. (1993) "Liposomal drug delivery to the eye and lungs: a preliminary electron microscopy study", J. Microencapsul. 10, 35-44.
56. Small, D.M., Dais, M., Wong, M. and Tang-Liu, D.D. (1997) "Influence of pH and buffer concentration on the ocular bioavailability of ophthalmic AGN 191103 formulations in albino rabbits", Int. J. Pharm. 149, 195-201.
57. Suhonen, P., Jarvinen, T., Peura, P. and Urtti, A. (1991) "Permeability of pilocarpic acid diesters across albino rabbit cornea in vitro", Int. J. Pharm. 74, 221-228.
58. Taniguchi, K., Yamamoto, Y., Itakura, K., Miichi, H. and Hayashi, S. (1988) "Assessment of ocular irritability of liposome preparations", J. Pharmacobiodyn. 11, 607-611.
59. Tiffany, J.M. (1994) "Composition and biophysical properties of the tear film: knowledge and uncertainty", In: Sullivan, D.A., ed., Lacrimal Gland, Tear Film, and Dry Eye Syndromes (Plenum Press, New York), pp 231-238.
60. Velpandian, T., Gupta, S.K., Gupta, Y.K., Biswas, N.R. and Agarwal, H.C. (1999) "Ocular drug targeting by liposomes and their corneal interactions", J. Microencapsul. 16, 243-250.
61. Yamada, M., Kawai, M., Mochizuki, H., Hata, Y. and Mashima, Y. (1998) "Fluorophotometric measurement of the buffering action of human tears in vivo", Curr. Eye Res. 17, 1005-1009.
62. Zaki, I., Fitzgerald, P., Hardy, J.G. and Wilson, C.G. (1986) "A comparison of the effect of viscosity on the precorneal residence of solutions in rabbit and man", J. Pharm. Pharmacol. 38, 463-466.
63. Zimmer, A. and Kreuter, J. (1995) "Microspheres and nanoparticles used in ocular delivery systems", Adv. Drug Deliv. Rev. 16, 61-73.
64. Zimmer, A., Kreuter, J. and Robinson, J.R. (1991) "Studies on the transport pathway of PBCA nanoparticles in ocular tissues", J. Microencapsul. 8, 497-504.