Expression of human endogenous retrovirus K is stimulated by ultraviolet radiation in melanoma

Pigment Cell and Melanoma Research

Volumn 24, Issue 4, 2011, Pages 656-665

  Schanab, Oliver ^a   Humer, Johannes ^b   Gleiss, Andreas ^c   Mikula, Mario ^a,c   Sturlan, Sanda ^b   Grunt, Susanne ^a,b   Okamoto, Ichiro ^a   Muster, Thomas ^a,b   Pehamberger, Hubert ^a   Waltenberger, Andrea ^a,b  

^a Universitatsklinik fur Dermatologie   (Austria)

^b Avir Green Hills Biotechnology AG   (Austria)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Human endogenous retrovirus type K; Melanoma; Ultraviolet radiation

Indexed keywords

POL PROTEIN; VIRUS ENVELOPE PROTEIN;

ARTICLE; ENDOGENOUS RETROVIRUS; GENE SEQUENCE; HUMAN; HUMAN CELL; HUMAN ENDOGENOUS RETROVIRUS K; IN VITRO STUDY; MELANOMA; MELANOMA CELL; PATHOGENESIS; RADIATION DOSE; REAL TIME POLYMERASE CHAIN REACTION; ULTRAVIOLET RADIATION; VIRUS EXPRESSION;

BASE SEQUENCE; CELL LINE, TUMOR; ENDOGENOUS RETROVIRUSES; GENE EXPRESSION REGULATION, VIRAL; GENE PRODUCTS, POL; HUMANS; MELANOMA; RNA, MESSENGER; SKIN NEOPLASMS; TRANSCRIPTIONAL ACTIVATION; ULTRAVIOLET RAYS; VIRION; VIRUS ACTIVATION;

HUMAN ENDOGENOUS RETROVIRUS K; HUMAN ENDOGENOUS RETROVIRUSES;

EID: 80051875022     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2011.00860.x     Document Type: Article

References (51)

1. Arnold, B.A., Hepler, R.W., and Keller, P.M. (1998). One-step fluorescent probe product-enhanced reverse transcriptase assay. BioTechniques 25, 98-106.
2. Bannert, N., and Kurth, R. (2004). Retroelements and the human genome: new perspectives on an old relation. Proc. Natl Acad. Sci. USA 101(Suppl 2), 14572-14579.
3. Benjamin, C.L., Melnikova, V.O., and Ananthaswamy, H.N. (2007). Models and mechanisms in malignant melanoma. Mol. Carcinog. 46, 671-678.
4. Boese, A., Sauter, M., Galli, U., Best, B., Herbst, H., Mayer, J., Kremmer, E., Roemer, K., and Mueller-Lantzsch, N. (2000). Human endogenous retrovirus protein cORF supports cell transformation and associates with the promyelocytic leukemia zinc finger protein. Oncogene 19, 4328-4336.
5. Boller, K., Konig, H., Sauter, M., Mueller-Lantzsch, N., Lower, R., Lower, J., and Kurth, R. (1993). Evidence that HERV-K is the endogenous retrovirus sequence that codes for the human teratocarcinoma-derived retrovirus HTDV. Virology 196, 349-353.
6. Bronson, D.L., Ritzi, D.M., Fraley, E.E., and Dalton, A.J. (1978). Morphologic evidence for retrovirus production by epithelial cells derived from a human testicular tumor metastasis. J. Natl Cancer Inst. 60, 1305-1308.
7. Buscher, K., Trefzer, U., Hofmann, M., Sterry, W., Kurth, R., and Denner, J. (2005). Expression of human endogenous retrovirus K in melanomas and melanoma cell lines. Cancer Res. 65, 4172-4180.
8. Canaani, E., Dreazen, O., Klar, A., Rechavi, G., Ram, D., Cohen, J.B., and Givol, D. (1983). Activation of the c-mos oncogene in a mouse plasmacytoma by insertion of an endogenous intracisternal A-particle genome. Proc. Natl Acad. Sci. USA 80, 7118-7122.
9. Carlson, J.A., Ross, J.S., Slominski, A., Linette, G., Mysliborski, J., Hill, J., and Mihm Jr, M. (2005). Molecular diagnostics in melanoma. J. Am. Acad. Dermatol. 52, 743-775.
10. De Fabo, E.C., Noonan, F.P., Fears, T., and Merlino, G. (2004). Ultraviolet B but not ultraviolet A radiation initiates melanoma. Cancer Res. 64, 6372-6376.
11. Denne, M., Sauter, M., Armbruester, V., Licht, J.D., Roemer, K., and Mueller-Lantzsch, N. (2007). Physical and functional interactions of human endogenous retrovirus proteins Np9 and rec with the promyelocytic leukemia zinc finger protein. J. Virol. 81, 5607-5616.
12. Depil, S., Roche, C., Dussart, P., and Prin, L. (2002). Expression of a human endogenous retrovirus, HERV-K, in the blood cells of leukemia patients. Leukemia 16, 254-259.
13. Elwood, J.M., and Jopson, J. (1997). Melanoma and sun exposure: an overview of published studies. Int. J. Cancer 73, 198-203.
14. Enk, C.D., Jacob-Hirsch, J., Gal, H., Verbovetski, I., Amariglio, N., Mevorach, D., Ingber, A., Givol, D., Rechavi, G., and Hochberg, M. (2006). The UVB-induced gene expression profile of human epidermis in vivo is different from that of cultured keratinocytes. Oncogene 25, 2601-2614.
15. Galli, U.M., Sauter, M., Lecher, B., Maurer, S., Herbst, H., Roemer, K., and Mueller-Lantzsch, N. (2005). Human endogenous retrovirus rec interferes with germ cell development in mice and may cause carcinoma in situ, the predecessor lesion of germ cell tumors. Oncogene 24, 3223-3228.
16. Gilchrest, B.A., Eller, M.S., Geller, A.C., and Yaar, M. (1999). The pathogenesis of melanoma induced by ultraviolet radiation. N. Engl. J. Med. 340, 1341-1348.
17. de Gruijl, F.R., and Rebel, H. (2008). Early events in UV carcinogenesis--DNA damage, target cells and mutant p53 foci. Photochem. Photobiol. 84, 382-387.
18. Herbst, H., Sauter, M., and Mueller-Lantzsch, N. (1996). Expression of human endogenous retrovirus K elements in germ cell and trophoblastic tumors. Am. J. Pathol. 149, 1727-1735.
19. Hirschl, S., Schanab, O., Seppele, H., Waltenberger, A., Humer, J., Wolff, K., Pehamberger, H., and Muster, T. (2007). Sequence variability of retroviral particles derived from human melanoma cells melanoma-associated retrovirus. Virus Res. 123, 211-215.
20. Hocker, T., and Tsao, H. (2007). Ultraviolet radiation and melanoma: a systematic review and analysis of reported sequence variants. Hum. Mutat. 28, 578-588.
21. Hohenadl, C., Germaier, H., Walchner, M., Hagenhofer, M., Herrmann, M., Sturzl, M., Kind, P., Hehlmann, R., Erfle, V., and Leib-Mosch, C. (1999). Transcriptional activation of endogenous retroviral sequences in human epidermal keratinocytes by UVB irradiation. J. Invest Dermatol. 113, 587-594.
22. Jemal, A., Siegel, R., Ward, E., Murray, T., Xu, J., Smigal, C., and Thun, M.J. (2006). Cancer statistics, 2006. CA Cancer J.Clin. 56, 106-130.
23. Kazazian Jr, H.H. (1998). Mobile elements and disease. Curr. Opin. Genet. Dev. 8, 343-350.
24. Kazazian Jr, H.H., Wong, C., Youssoufian, H., Scott, A.F., Phillips, D.G., and Antonarakis, S.E. (1988). Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man. Nature 332, 164-166.
25. Lower, R., Lower, J., Frank, H., Harzmann, R., and Kurth, R. (1984). Human teratocarcinomas cultured in vitro produce unique retrovirus-like viruses. J.Gen.Virol. 65(Pt 5), 887-898.
26. Lower, R., Lower, J., and Kurth, R. (1996). The viruses in all of us: characteristics and biological significance of human endogenous retrovirus sequences. Proc. Natl Acad. Sci. USA 93, 5177-5184.
27. Maddodi, N., and Setaluri, V. (2008). Role of UV in cutaneous melanoma. Photochem. Photobiol. 84, 528-536.
28. Mangeney, M., Pothlichet, J., Renard, M., Ducos, B., and Heidmann, T. (2005). Endogenous retrovirus expression is required for murine melanoma tumor growth in vivo. Cancer Res. 65, 2588-2591.
29. Mayer, J., Sauter, M., Racz, A., Scherer, D., Mueller-Lantzsch, N., and Meese, E. (1999). An almost-intact human endogenous retrovirus K on human chromosome 7. Nat. Genet. 21, 257-258.
30. Medstrand, P., and Blomberg, J. (1993). Characterization of novel reverse transcriptase encoding human endogenous retroviral sequences similar to type A and type B retroviruses: differential transcription in normal human tissues. J. Virol. 67, 6778-6787.
31. Miki, Y., Nishisho, I., Horii, A., Miyoshi, Y., Utsunomiya, J., Kinzler, K.W., Vogelstein, B., and Nakamura, Y. (1992). Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer. Cancer Res. 52, 643-645.
32. Morse, B., Rotherg, P.G., South, V.J., Spandorfer, J.M., and Astrin, S.M. (1988). Insertional mutagenesis of the myc locus by a LINE-1 sequence in a human breast carcinoma. Nature 333, 87-90.
33. Moyes, D., Griffiths, D.J., and Venables, P.J. (2007). Insertional polymorphisms: a new lease of life for endogenous retroviruses in human disease. Trends Genet. 23, 326-333.
34. Muster, T., Waltenberger, A., Grassauer, A. et al. (2003). An endogenous retrovirus derived from human melanoma cells. Cancer Res. 63, 8735-8741.
35. Oricchio, E., Sciamanna, I., Beraldi, R., Tolstonog, G.V., Schumann, G.G., and Spadafora, C. (2007). Distinct roles for LINE-1 and HERV-K retroelements in cell proliferation, differentiation and tumor progression. Oncogene 26, 4226-4233.
36. Pollock, P.M., Yu, F., Qiu, L., Parsons, P.G., and Hayward, N.K. (1995). Evidence for u.v. induction of CDKN2 mutations in melanoma cell lines. Oncogene 11, 663-668.
37. Reiche, J., Pauli, G., and Ellerbrok, H. (2010). Differential expression of human endogenous retrovirus K transcripts in primary human melanocytes and melanoma cell lines after UV irradiation. Melanoma Res. 20, 435-440.
38. Ruprecht, K., Mayer, J., Sauter, M., Roemer, K., and Mueller-Lantzsch, N. (2008). Endogenous retroviruses and cancer. Cell. Mol. Life Sci. 65, 3366-3382.
39. Ryan, F.P. (2009). An alternative approach to medical genetics based on modern evolutionary biology. Part 4: HERVs in cancer. J. R. Soc. Med. 102, 474-480.
40. Sauter, M., Schommer, S., Kremmer, E., Remberger, K., Dolken, G., Lemm, I., Buck, M., Best, B., Neumann-Haefelin, D., and Mueller-Lantzsch, N. (1995). Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas. J. Virol. 69, 414-421.
41. Seifarth, W., Baust, C., Murr, A., Skladny, H., Krieg-Schneider, F., Blusch, J., Werner, T., Hehlmann, R., and Leib-Mosch, C. (1998). Proviral structure, chromosomal location, and expression of HERV-K-T47D, a novel human endogenous retrovirus derived from T47D particles. J. Virol. 72, 8384-8391.
42. Seifarth, W., Frank, O., Zeilfelder, U., Spiess, B., Greenwood, A.D., Hehlmann, R., and Leib-Mosch, C. (2005). Comprehensive analysis of human endogenous retrovirus transcriptional activity in human tissues with a retrovirus-specific microarray. J. Virol. 79, 341-352.
43. Serafino, A., Balestrieri, E., Pierimarchi, P. et al. (2009). The activation of human endogenous retrovirus K (HERV-K) is implicated in melanoma cell malignant transformation. Exp. Cell Res. 315, 849-862.
44. Singh, S., Kaye, S., Gore, M.E., McClure, M.O., and Bunker, C.B. (2009). The role of human endogenous retroviruses in melanoma. Br. J. Dermatol. 161, 1225-1231.
45. Stauffer, Y., Theiler, G., Sperisen, P., Lebedev, Y., and Jongeneel, C.V. (2004). Digital expression profiles of human endogenous retroviral families in normal and cancerous tissues. Cancer Immun. 4, 2.
46. Valerie, K., Delers, A., Bruck, C., Thiriart, C., Rosenberg, H., Debouck, C., and Rosenberg, M. (1988). Activation of human immunodeficiency virus type 1 by DNA damage in human cells. Nature 333, 78-81.
47. Venter, J.C., Adams, M.D., Myers, E.W. et al. (2001). The sequence of the human genome. Science 291, 1304-1351.
48. Wang-Johanning, F., Frost, A.R., Johanning, G.L., Khazaeli, M.B., LoBuglio, A.F., Shaw, D.R., and Strong, T.V. (2001). Expression of human endogenous retrovirus k envelope transcripts in human breast cancer. Clin. Cancer Res. 7, 1553-1560.
49. Wang-Johanning, F., Liu, J., Rycaj, K., Huang, M., Tsai, K., Rosen, D.G., Chen, D.T., Lu, D.W., Barnhart, K.F., and Johanning, G.L. (2007). Expression of multiple human endogenous retrovirus surface envelope proteins in ovarian cancer. Int. J. Cancer 120, 81-90.
50. Whiteman, D.C., Whiteman, C.A., and Green, A.C. (2001). Childhood sun exposure as a risk factor for melanoma: a systematic review of epidemiologic studies. Cancer Causes Control 12, 69-82.
51. Whiteman, D.C., Stickley, M., Watt, P., Hughes, M.C., Davis, M.B., and Green, A.C. (2006). Anatomic site, sun exposure, and risk of cutaneous melanoma. J. Clin. Oncol. 24, 3172-3177.