메뉴 건너뛰기




Volumn 129, Issue 4, 2011, Pages 1703-1709

Anthocyanin-rich Mulberry extract inhibit the gastric cancer cell growth in vitro and xenograft mice by inducing signals of p38/p53 and c-jun

Author keywords

Aanthocyanin; AGS; Apoptosis; Cyanidine; Mulberry; Tumorigenesis

Indexed keywords

AANTHOCYANIN; AGS; CYANIDINE; MULBERRY; TUMORIGENESIS;

EID: 80051802279     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2011.06.035     Document Type: Article
Times cited : (61)

References (32)
  • 1
    • 33845744294 scopus 로고    scopus 로고
    • Delphinidin, an anthocyanidin in pigmented fruits and vegetables, protects human HaCaT keratinocytes and mouse skin against UVB-mediated oxidative stress and apoptosis
    • DOI 10.1038/sj.jid.5700510, PII 5700510
    • F. Afaq, D.N. Syed, A. Malik, N. Hadi, S. Sarfaraz, and M.H. Kweon Delphinidin, an anthocyanidin in pigmented fruits and vegetables, protects human HaCaT keratinocytes and mouse skin against UVB-mediated oxidative stress and apoptosis The Journal of Investigative Dermatology 127 1 2007 222 232 (Pubitemid 46005682)
    • (2007) Journal of Investigative Dermatology , vol.127 , Issue.1 , pp. 222-232
    • Afaq, F.1    Syed, D.N.2    Malik, A.3    Hadi, N.4    Sarfaraz, S.5    Kweon, M.-H.6    Khan, N.7    Zaid, M.A.8    Mukhtar, H.9
  • 2
    • 0036784966 scopus 로고    scopus 로고
    • Comparative antiproliferative and apoptotic effects of resveratrol, epsilon-viniferin and vine-shots derived polyphenols (vineatrols) on chronic B lymphocytic leukemia cells and normal human lymphocytes
    • C. Billard, J.C. Izard, V. Roman, C. Kern, C. Mathiot, and F. Mentz Comparative antiproliferative and apoptotic effects of resveratrol, epsilon-viniferin and vine-shots derived polyphenols (vineatrols) on chronic B lymphocytic leukemia cells and normal human lymphocytes Leukemia and Lymphoma 43 10 2002 1991 2002
    • (2002) Leukemia and Lymphoma , vol.43 , Issue.10 , pp. 1991-2002
    • Billard, C.1    Izard, J.C.2    Roman, V.3    Kern, C.4    Mathiot, C.5    Mentz, F.6
  • 3
    • 28244433897 scopus 로고    scopus 로고
    • Overcoming fas-mediated apoptosis accelerates Helicobacter-induced gastric cancer in mice
    • DOI 10.1158/0008-5472.CAN-05-1802
    • X. Cai, C. Stoicov, H. Li, J. Carlson, M. Whary, and J.G. Fox Overcoming Fas-mediated apoptosis accelerates Helicobacter-induced gastric cancer in mice Cancer Research 65 23 2005 10912 10920 (Pubitemid 41713359)
    • (2005) Cancer Research , vol.65 , Issue.23 , pp. 10912-10920
    • Cai, X.1    Stoicov, C.2    Li, H.3    Carlson, J.4    Whary, M.5    Fox, J.G.6    Houghton, J.7
  • 4
    • 19444383434 scopus 로고    scopus 로고
    • Hibiscus anthocyanins rich extract-induced apoptotic cell death in human promyelocytic leukemia cells
    • Y.C. Chang, H.P. Huang, J.D. Hsu, S.F. Yang, and C.J. Wang Hibiscus anthocyanins rich extract-induced apoptotic cell death in human promyelocytic leukemia cells Toxicology and Applied Pharmacology 205 3 2005 201 212
    • (2005) Toxicology and Applied Pharmacology , vol.205 , Issue.3 , pp. 201-212
    • Chang, Y.C.1    Huang, H.P.2    Hsu, J.D.3    Yang, S.F.4    Wang, C.J.5
  • 5
    • 33644843641 scopus 로고    scopus 로고
    • Molecular mechanisms of human carcinogenesis
    • Coleman, W. B.; & Tsongalis, G. J. (2006). Molecular mechanisms of human carcinogenesis. EXS (96), 321-349.
    • (2006) EXS , Issue.96 , pp. 321-349
    • Coleman, W.B.1    Tsongalis, G.J.2
  • 6
    • 0036031772 scopus 로고    scopus 로고
    • Therapeutics targeting signal transduction for patients with colorectal carcinoma
    • DOI 10.1093/bmb/64.1.227
    • J.S. de Bono, and E.K. Rowinsky Therapeutics targeting signal transduction for patients with colorectal carcinoma British Medical Bulletin 64 2002 227 254 (Pubitemid 35238589)
    • (2002) British Medical Bulletin , vol.64 , pp. 227-254
    • De Bono, J.S.1    Rowinsky, E.K.2
  • 7
    • 2342464082 scopus 로고    scopus 로고
    • Induction of apoptosis in two human leukemia cell lines as well as differentiation in human promyelocytic cells by cyanidin-3-O-β- glucopyranoside
    • DOI 10.1016/j.bcp.2004.02.021, PII S0006295204001406
    • C. Fimognari, F. Berti, M. Nusse, G. Cantelli-Forti, and P. Hrelia Induction of apoptosis in two human leukemia cell lines as well as differentiation in human promyelocytic cells by cyanidin-3-o-beta- glucopyranoside Biochemical Pharmacology 67 11 2004 2047 2056 (Pubitemid 38595486)
    • (2004) Biochemical Pharmacology , vol.67 , Issue.11 , pp. 2047-2056
    • Fimognari, C.1    Berti, F.2    Nusse, M.3    Cantelli-Forti, G.4    Hrelia, P.5
  • 8
    • 16844380124 scopus 로고    scopus 로고
    • Pharmacokinetics of anthocyanidin-3-glycosides following consumption of Hibiscus sabdariffa L. extract
    • DOI 10.1177/0091270004270561
    • T. Frank, M. Janssen, M. Netzel, G. Strass, A. Kler, and E. Kriesl Pharmacokinetics of anthocyanidin-3-glycosides following consumption of Hibiscus sabdariffa L. extract Journal of Clinical Pharmacology 45 2 2005 203 210 (Pubitemid 40490444)
    • (2005) Journal of Clinical Pharmacology , vol.45 , Issue.2 , pp. 203-210
    • Frank, T.1    Janssen, M.2    Netzel, M.3    Strass, G.4    Kler, A.5    Kriesl, E.6    Bitsch, I.7
  • 9
    • 0027291905 scopus 로고
    • Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands
    • M.G. Hertog, P.C. Hollman, M.B. Katan, and D. Kromhout Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands Nutrition and Cancer 20 1 1993 21 29 (Pubitemid 23225364)
    • (1993) Nutrition and Cancer , vol.20 , Issue.1 , pp. 21-29
    • Hertog, M.G.L.1    Hollman, P.C.H.2    Katan, M.B.3    Kromhout, D.4
  • 10
    • 54349118993 scopus 로고    scopus 로고
    • Chemoinhibitory effect of mulberry anthocyanins on melanoma metastasis involved in the Ras/PI3K pathway
    • H.P. Huang, Y.W. Shih, Y.C. Chang, C.N. Hung, and C.J. Wang Chemoinhibitory effect of mulberry anthocyanins on melanoma metastasis involved in the Ras/PI3K pathway Journal of Agricultural and Food Chemistry 56 19 2008 9286 9293
    • (2008) Journal of Agricultural and Food Chemistry , vol.56 , Issue.19 , pp. 9286-9293
    • Huang, H.P.1    Shih, Y.W.2    Chang, Y.C.3    Hung, C.N.4    Wang, C.J.5
  • 12
    • 33846599252 scopus 로고    scopus 로고
    • Pathogenesis and treatment of gastric carcinoma: An up-date with brief review
    • F.A. Khan, and A.N. Shukla Pathogenesis and treatment of gastric carcinoma: An up-date with brief review Journal of Cancer Research and Therapeutics 2 4 2006 196 199
    • (2006) Journal of Cancer Research and Therapeutics , vol.2 , Issue.4 , pp. 196-199
    • Khan, F.A.1    Shukla, A.N.2
  • 13
    • 0033106484 scopus 로고    scopus 로고
    • A mechanism of repression of TGFfβ/Smad signaling by oncogenic Ras
    • M. Kretzschmar, J. Doody, I. Timokhina, and J. Massague A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras Genes and Development 13 7 1999 804 816 (Pubitemid 29169840)
    • (1999) Genes and Development , vol.13 , Issue.7 , pp. 804-816
    • Kretzschmar, M.1    Doody, J.2    Timokhina, I.3    Massague, J.4
  • 14
    • 0035866369 scopus 로고    scopus 로고
    • Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis
    • S. Lacour, A. Hammann, A. Wotawa, L. Corcos, E. Solary, and M.T. Dimanche-Boitrel Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis Cancer Research 61 4 2001 1645 1651 (Pubitemid 34292600)
    • (2001) Cancer Research , vol.61 , Issue.4 , pp. 1645-1651
    • Lacour, S.1    Hammann, A.2    Wotawa, A.3    Corcos, L.4    Solary, E.5    Dimanche-Boitrel, M.-T.6
  • 15
    • 31544458038 scopus 로고    scopus 로고
    • Immunohistochemical expression of bcl-2, bcl-xL, bax, p53 proteins in gastric adenoma and adenocarcinoma
    • D.S. Lee, S.B. Kang, J.T. Baek, S.W. Nam, K.M. Lee, and B.M. Ahn Immunohistochemical expression of bcl-2, bcl-xL, bax, p53 proteins in gastric adenoma and adenocarcinoma The Korean Journal of Gastroenterology 45 6 2005 394 400
    • (2005) The Korean Journal of Gastroenterology , vol.45 , Issue.6 , pp. 394-400
    • Lee, D.S.1    Kang, S.B.2    Baek, J.T.3    Nam, S.W.4    Lee, K.M.5    Ahn, B.M.6
  • 17
    • 0036182725 scopus 로고    scopus 로고
    • Alterations of E-cadherin, α-catenin and β-catenin expression in neuroendocrine tumors of the gastrointestinal tract
    • DOI 10.1007/s004280100529
    • C.C. Li, B. Xu, M. Hirokawa, Z. Qian, K. Yoshimoto, and H. Horiguchi Alterations of E-cadherin, alpha-catenin and beta-catenin expression in neuroendocrine tumors of the gastrointestinal tract Virchows Archiv 440 2 2002 145 154 (Pubitemid 34169851)
    • (2002) Virchows Archiv , vol.440 , Issue.2 , pp. 145-154
    • Li, C.1    Xu, B.2    Hirokawa, M.3    Qian, Z.4    Yoshimoto, K.5    Horiguchi, H.6    Tashiro, T.7    Sano, T.8
  • 18
    • 20344400374 scopus 로고    scopus 로고
    • Hibiscus polyphenol-rich extract induces apoptosis in human gastric carcinoma cells via p53 phosphorylation and p38 MAPK/FasL cascade pathway
    • H.H. Lin, H.P. Huang, C.C. Huang, J.H. Chen, and C.J. Wang Hibiscus polyphenol-rich extract induces apoptosis in human gastric carcinoma cells via p53 phosphorylation and p38 MAPK/FasL cascade pathway Molecular Carcinogenesis 43 2 2005 86 99
    • (2005) Molecular Carcinogenesis , vol.43 , Issue.2 , pp. 86-99
    • Lin, H.H.1    Huang, H.P.2    Huang, C.C.3    Chen, J.H.4    Wang, C.J.5
  • 19
    • 48749106385 scopus 로고    scopus 로고
    • Mulberry anthocyanin extracts inhibit LDL oxidation and macrophage-derived foam cell formation induced by oxidative LDL
    • L.K. Liu, H.J. Lee, Y.W. Shih, C.C. Chyau, and C.J. Wang Mulberry anthocyanin extracts inhibit LDL oxidation and macrophage-derived foam cell formation induced by oxidative LDL Journal of Food Science 73 6 2008 H113 H121
    • (2008) Journal of Food Science , vol.73 , Issue.6
    • Liu, L.K.1    Lee, H.J.2    Shih, Y.W.3    Chyau, C.C.4    Wang, C.J.5
  • 23
    • 33749241899 scopus 로고    scopus 로고
    • Anthocyanins: Structural characteristics that result in unique metabolic patterns and biological activities
    • DOI 10.1080/10715760600758522, PII NP0262105217K647, Polyphenols and Health
    • R.L. Prior, and X. Wu Anthocyanins: structural characteristics that result in unique metabolic patterns and biological activities Free Radical Research 40 10 2006 1014 1028 (Pubitemid 44480542)
    • (2006) Free Radical Research , vol.40 , Issue.10 , pp. 1014-1028
    • Prior, R.L.1    Wu, X.2
  • 24
    • 67349150698 scopus 로고    scopus 로고
    • Targeting apoptosis as an approach for gastrointestinal cancer therapy
    • L. Qiao, and B.C. Wong Targeting apoptosis as an approach for gastrointestinal cancer therapy Drug Resistance Updates 12 3 2009 55 64
    • (2009) Drug Resistance Updates , vol.12 , Issue.3 , pp. 55-64
    • Qiao, L.1    Wong, B.C.2
  • 25
    • 33846131249 scopus 로고    scopus 로고
    • Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro
    • DOI 10.1021/jf061750g
    • N.P. Seeram, L.S. Adams, Y. Zhang, R. Lee, D. Sand, and H.S. Scheuller Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro Journal of Agricultural and Food Chemistry 54 25 2006 9329 9339 (Pubitemid 46086089)
    • (2006) Journal of Agricultural and Food Chemistry , vol.54 , Issue.25 , pp. 9329-9339
    • Seeram, N.P.1    Adams, L.S.2    Zhang, Y.3    Lee, R.4    Sand, D.5    Scheuller, H.S.6    Heber, D.7
  • 28
    • 0141675107 scopus 로고    scopus 로고
    • Preclinical evaluation of therapeutic effects of targeted cytotoxic analogs of somatostatin and bombesin on human gastric carcinomas
    • DOI 10.1002/cncr.11649
    • K. Szepeshazi, A.V. Schally, A. Nagy, B.W. Wagner, A.M. Bajo, and G. Halmos Preclinical evaluation of therapeutic effects of targeted cytotoxic analogs of somatostatin and bombesin on human gastric carcinomas Cancer 98 7 2003 1401 1410 (Pubitemid 37151494)
    • (2003) Cancer , vol.98 , Issue.7 , pp. 1401-1410
    • Szepeshazi, K.1    Schally, A.V.2    Nagy, A.3    Wagner, B.W.4    Bajo, A.M.5    Halmos, G.6
  • 30
    • 51349128983 scopus 로고    scopus 로고
    • Anthocyanins and their role in cancer prevention
    • L.S. Wang, and G.D. Stoner Anthocyanins and their role in cancer prevention Cancer Letters 269 2 2008 281 290
    • (2008) Cancer Letters , vol.269 , Issue.2 , pp. 281-290
    • Wang, L.S.1    Stoner, G.D.2
  • 31
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Z. Xia, M. Dickens, J. Raingeaud, R.J. Davis, and M.E. Greenberg Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis Science 270 5240 1995 1326 1331
    • (1995) Science , vol.270 , Issue.5240 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.