-
2
-
-
0028082161
-
Protein kinase C - A question of specificity
-
Dekker LV, Parker PJ. Protein kinase C-a question of specificity. Trends Biochem Sci 1994;19:73-7.
-
(1994)
Trends Biochem Sci
, vol.19
, pp. 73-77
-
-
Dekker, L.V.1
Parker, P.J.2
-
3
-
-
0028811653
-
Protein kinase C: Structure, function, and regulation
-
Newton AC. Protein kinase C: structure, function, and regulation. J Biol Chem 1995;270:28495-8.
-
(1995)
J Biol Chem
, vol.270
, pp. 28495-28498
-
-
Newton, A.C.1
-
4
-
-
0028141496
-
Transformation of mammalian cells by constitutively active MAP kinase kinase
-
Mansour SJ, Matten WT, Hermann AS, et al. Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 1994;265:966-70.
-
(1994)
Science
, vol.265
, pp. 966-970
-
-
Mansour, S.J.1
Matten, W.T.2
Hermann, A.S.3
-
5
-
-
0032510109
-
Signal transduction pathways activated and required for mammary carcinogenesis in response to specific oncogenes
-
Amundadottir LT, Leder P. Signal transduction pathways activated and required for mammary carcinogenesis in response to specific oncogenes. Oncogene 1998;16:737-46.
-
(1998)
Oncogene
, vol.16
, pp. 737-746
-
-
Amundadottir, L.T.1
Leder, P.2
-
6
-
-
0024323584
-
Elevated protein kinase C expression in human breast tumor biopsies relative to normal breast tissue
-
O'Brian C, Vogel VG, Singletary SE, Ward NE. Elevated protein kinase C expression in human breast tumor biopsies relative to normal breast tissue. Cancer Res 1989;49:3215-7.
-
(1989)
Cancer Res
, vol.49
, pp. 3215-3217
-
-
O'Brian, C.1
Vogel, V.G.2
Singletary, S.E.3
Ward, N.E.4
-
7
-
-
0000939974
-
Elevation of protein kinase A and protein kinase C activities in malignant as compared with normal human breast tissue
-
Gordge PC, Hulme MJ, Clegg RA, Miller WR. Elevation of protein kinase A and protein kinase C activities in malignant as compared with normal human breast tissue. Eur J Cancer 1996;32A:2120-6.
-
(1996)
Eur J Cancer
, vol.32 A
, pp. 2120-2126
-
-
Gordge, P.C.1
Hulme, M.J.2
Clegg, R.A.3
Miller, W.R.4
-
8
-
-
0023526075
-
2+-dependent protein kinase of human mammary carcinoma cells: Inverse relationship to estrogen receptors
-
2+-dependent protein kinase of human mammary carcinoma cells: inverse relationship to estrogen receptors. Int J Cancer 1987;40:344-8.
-
(1987)
Int J Cancer
, vol.40
, pp. 344-348
-
-
Borner, C.1
Wyss, R.2
Regazzi, R.3
Eppenberger, U.4
Fabbro, D.5
-
9
-
-
0027016222
-
Involvement of protein kinase C in the growth regulation of human breast cancer cells
-
Fabbro D, Kung W, Costa SD, Borner C, Regenass U, Eppenberger U. Involvement of protein kinase C in the growth regulation of human breast cancer cells. Cancer Treat Res 1992;61:229-48.
-
(1992)
Cancer Treat Res
, vol.61
, pp. 229-248
-
-
Fabbro, D.1
Kung, W.2
Costa, S.D.3
Borner, C.4
Regenass, U.5
Eppenberger, U.6
-
10
-
-
0025118712
-
Protein kinase C subspecies in estrogen receptor-positive and - Negative human breast cancer cell lines
-
Bignon E, Ogita K, Kishimoto A, Nishizuka Y. Protein kinase C subspecies in estrogen receptor-positive and - negative human breast cancer cell lines. Biochem Biophys Res Commun 1990;171:1071-8.
-
(1990)
Biochem Biophys Res Commun
, vol.171
, pp. 1071-1078
-
-
Bignon, E.1
Ogita, K.2
Kishimoto, A.3
Nishizuka, Y.4
-
12
-
-
0035866371
-
Elevated protein kinase C βII is an early promotive event in colon carcinogenesis
-
Gokmen-Polar Y, Murray NR, Velasco MA, Gatalica Z, Fields AP. Elevated protein kinase C βII is an early promotive event in colon carcinogenesis. Cancer Res 2001;61:1375-81.
-
(2001)
Cancer Res
, vol.61
, pp. 1375-1381
-
-
Gokmen-Polar, Y.1
Murray, N.R.2
Velasco, M.A.3
Gatalica, Z.4
Fields, A.P.5
-
13
-
-
0033577858
-
Overexpression of protein kinase C βII induces colonic hyperproliferation and increased sensitivity to colon carcinogenesis
-
Murray NR, Davidson LA, Chapkin RS, Clay Gustafson W, Schattenberg DG, Fields AP. Overexpression of protein kinase C βII induces colonic hyperproliferation and increased sensitivity to colon carcinogenesis. J Cell Biol 1999;145:699-711.
-
(1999)
J Cell Biol
, vol.145
, pp. 699-711
-
-
Murray, N.R.1
Davidson, L.A.2
Chapkin, R.S.3
Clay Gustafson, W.4
Schattenberg, D.G.5
Fields, A.P.6
-
14
-
-
0038515329
-
Role of cyclooxygenase 2 in protein kinase C βII-mediated colon carcinogenesis
-
Yu W, Murray NR, Weems C, et al. Role of cyclooxygenase 2 in protein kinase C βII-mediated colon carcinogenesis. J Biol Chem 2003;278:11167-74.
-
(2003)
J Biol Chem
, vol.278
, pp. 11167-11174
-
-
Yu, W.1
Murray, N.R.2
Weems, C.3
-
15
-
-
0033524382
-
Increased transforming growth factor-α levels in human colon carcinoma cell unes over-expressing protein kinase C
-
Maruvada P, Levine AE. Increased transforming growth factor-α levels in human colon carcinoma cell unes over-expressing protein kinase C. Int J Cancer 1999;80:72-7.
-
(1999)
Int J Cancer
, vol.80
, pp. 72-77
-
-
Maruvada, P.1
Levine, A.E.2
-
16
-
-
0141446032
-
Roles of specific isoforms of protein kinase C in the transcriptional control of cyclin D1 and related genes
-
Soh JW, Weinstein IB. Roles of specific isoforms of protein kinase C in the transcriptional control of cyclin D1 and related genes. J Biol Chem 2003;278:34709-16.
-
(2003)
J Biol Chem
, vol.278
, pp. 34709-34716
-
-
Soh, J.W.1
Weinstein, I.B.2
-
17
-
-
0027530449
-
Redundant cyclin overexpression and gene amplification in breast cancer cells
-
Keyomarsi K, Pardee AB. Redundant cyclin overexpression and gene amplification in breast cancer cells. Proc Natl Acad Sci U S A 1993;90:1112-6.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 1112-1116
-
-
Keyomarsi, K.1
Pardee, A.B.2
-
18
-
-
0028331092
-
Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining
-
Gillett C, Fantl V, Smith R, et al. Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining. Cancer Res 1994;54:1812-7.
-
(1994)
Cancer Res
, vol.54
, pp. 1812-1817
-
-
Gillett, C.1
Fantl, V.2
Smith, R.3
-
19
-
-
0029443097
-
The cyclin D1/PRAD1 oncogene in human neoplasia
-
Arnold A. The cyclin D1/PRAD1 oncogene in human neoplasia. J Investig Med 1995;43:543-9.
-
(1995)
J Investig Med
, vol.43
, pp. 543-549
-
-
Arnold, A.1
-
20
-
-
0027938209
-
Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age
-
Hunter T, Pines J. Cyclins and cancer. II: cyclin D and CDK inhibitors come of age. Cell 1994;79:573-82.
-
(1994)
Cell
, vol.79
, pp. 573-582
-
-
Hunter, T.1
Pines, J.2
-
22
-
-
0028970609
-
Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions
-
Albanese C, Johnson J, Watanabe G, et al. Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions. J Biol Chem 1995;270:23589-97.
-
(1995)
J Biol Chem
, vol.270
, pp. 23589-23597
-
-
Albanese, C.1
Johnson, J.2
Watanabe, G.3
-
23
-
-
0033545845
-
The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway
-
Shtutman M, Zhurinsky J, Simcha I, et al. The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway. Proc Natl Acad Sci U S A 1999;96:5522-7.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 5522-5527
-
-
Shtutman, M.1
Zhurinsky, J.2
Simcha, I.3
-
24
-
-
0033119801
-
β-catenin regulates expression of cyclin D1 in colon carcinoma cells
-
Tetsu O, McCormick F. β-Catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999;398:422-6.
-
(1999)
Nature
, vol.398
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
25
-
-
8944246315
-
(S)-13-(dimethylamino)methyl-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo [3,4-h][1,4,13]oxadiazacyclohexadecene- 1,3(2H)-d ione (LY333531) and related analogues: Isozyme selective inhibitors of protein kinase C β
-
Jirousek MR, Gillig JR, Gonzalez CM, et al. (S)-13-((Dimethylamino) methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo [3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C β. J Med Chem 1996;39:2664-71.
-
(1996)
J Med Chem
, vol.39
, pp. 2664-2671
-
-
Jirousek, M.R.1
Gillig, J.R.2
Gonzalez, C.M.3
-
26
-
-
0026765010
-
Mapping of epidermal growth factor-, serum-, and phorbol ester-responsive sequence elements in the c-jun promoter
-
Han TH, Lamph WW, Prywes R. Mapping of epidermal growth factor-, serum-, and phorbol ester-responsive sequence elements in the c-jun promoter. Mol Cell Biol 1992;12:4472-7.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 4472-4477
-
-
Han, T.H.1
Lamph, W.W.2
Prywes, R.3
-
27
-
-
0028048773
-
Two pathways for serum regulation of the c-fos serum response element require specific sequence elements and a minimal domain of serum response factor
-
Johansen FE, Prywes R. Two pathways for serum regulation of the c-fos serum response element require specific sequence elements and a minimal domain of serum response factor. Mol Cell Biol 1994;14:5920-8.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 5920-5928
-
-
Johansen, F.E.1
Prywes, R.2
-
28
-
-
2542464918
-
Phenol red in tissue culture media is a weak estrogen: Implications concerning the study of estrogen-responsive cells in culture
-
Berthois Y, Katzenellenbogen JA, Katzenellenbogen BS. Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture. Proc Natl Acad Sci U S A 1986;83:2496-500.
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 2496-2500
-
-
Berthois, Y.1
Katzenellenbogen, J.A.2
Katzenellenbogen, B.S.3
-
29
-
-
12644268232
-
Proteolytic activation of protein kinase C δ by an ICE/CED 3-like protease induces characteristics of apoptosis
-
Ghayur T, Hugunin M, Talanian RV, et al. Proteolytic activation of protein kinase C δ by an ICE/CED 3-like protease induces characteristics of apoptosis. J Exp Med 1996;184:2399-404.
-
(1996)
J Exp Med
, vol.184
, pp. 2399-2404
-
-
Ghayur, T.1
Hugunin, M.2
Talanian, R.V.3
-
30
-
-
0026786781
-
Role of protein kinase C in insulin's regulation of c-fos transcription
-
Messina JL, Standaert ML, Ishizuka T, Weinstock RS, Farese RV. Role of protein kinase C in insulin's regulation of c-fos transcription. J Biol Chem 1992;267:9223-8.
-
(1992)
J Biol Chem
, vol.267
, pp. 9223-9228
-
-
Messina, J.L.1
Standaert, M.L.2
Ishizuka, T.3
Weinstock, R.S.4
Farese, R.V.5
-
31
-
-
0027233072
-
Characterization of site-specific mutants altered at protein kinase C β1 isozyme autophosphorylation sites
-
Zhang J, Wang L, Petrin J, Bishop WR, Bond RW. Characterization of site-specific mutants altered at protein kinase C β1 isozyme autophosphorylation sites. Proc Natl Acad Sci U S A 1993;90:6130-4.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 6130-6134
-
-
Zhang, J.1
Wang, L.2
Petrin, J.3
Bishop, W.R.4
Bond, R.W.5
-
32
-
-
0345129995
-
Novel roles of specific isoforms of protein kinase C in activation of the c-fos serum response element
-
Soh JW, Lee EH, Prywes R, Weinstein IB. Novel roles of specific isoforms of protein kinase C in activation of the c-fos serum response element. Mol Cell Biol 1999;19:1313-24.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1313-1324
-
-
Soh, J.W.1
Lee, E.H.2
Prywes, R.3
Weinstein, I.B.4
-
33
-
-
0025167963
-
Overexpression of protein kinase C in HT29 colon cancer cells causes growth inhibition and tumor suppression
-
Choi PM, Tchou-Wong KM, Weinstein IB. Overexpression of protein kinase C in HT29 colon cancer cells causes growth inhibition and tumor suppression. Mol Cell Biol 1990;10:4650-7.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 4650-4657
-
-
Choi, P.M.1
Tchou-Wong, K.M.2
Weinstein, I.B.3
-
34
-
-
0029065363
-
Overexpression of protein kinase C β1 in the SW480 colon cancer cell line causes growth suppression
-
Goldstein DR, Cacace AM, Weinstein IB. Overexpression of protein kinase C β1 in the SW480 colon cancer cell line causes growth suppression. Carcinogenesis 1995;16:1121-6.
-
(1995)
Carcinogenesis
, vol.16
, pp. 1121-1126
-
-
Goldstein, D.R.1
Cacace, A.M.2
Weinstein, I.B.3
-
35
-
-
0034524218
-
Protein kinase C β1 is implicated in the regulation of neuroblastoma cell growth and proliferation
-
Svensson K, Zeidman R, Troller U, Schultz A, Larsson C. Protein kinase C β1 is implicated in the regulation of neuroblastoma cell growth and proliferation. Cell Growth Differ 2000;11:641-8.
-
(2000)
Cell Growth Differ
, vol.11
, pp. 641-648
-
-
Svensson, K.1
Zeidman, R.2
Troller, U.3
Schultz, A.4
Larsson, C.5
-
36
-
-
2542506202
-
Protein kinase C (PKC) βII induces cell invasion through a Ras/Mek-, PKCι/Rac1-dependent signaling pathway
-
Zhang J, Anastasiadis PZ, Liu Y, Thompson EA, Fields AP. Protein kinase C (PKC) βII induces cell invasion through a Ras/Mek-, PKCι/Rac1- dependent signaling pathway. J Biol Chem 2004;279:22118-23.
-
(2004)
J Biol Chem
, vol.279
, pp. 22118-22123
-
-
Zhang, J.1
Anastasiadis, P.Z.2
Liu, Y.3
Thompson, E.A.4
Fields, A.P.5
-
38
-
-
0031038588
-
Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase
-
Cai H, Smola U, Wixler V, et al. Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase. Mol Cell Biol 1997;17:732-41.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 732-741
-
-
Cai, H.1
Smola, U.2
Wixler, V.3
-
39
-
-
0032478610
-
Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C
-
Marais R, Light Y, Mason C, Paterson H, Olson MF, Marshall CJ. Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C. Science 1998;280:109-12.
-
(1998)
Science
, vol.280
, pp. 109-112
-
-
Marais, R.1
Light, Y.2
Mason, C.3
Paterson, H.4
Olson, M.F.5
Marshall, C.J.6
-
40
-
-
0023278635
-
Expression and properties of two types of protein kinase C: Alternative splicing from a single gene
-
Ono Y, Kikkawa U, Ogita K, et al. Expression and properties of two types of protein kinase C: alternative splicing from a single gene. Science 1987;236:1116-20.
-
(1987)
Science
, vol.236
, pp. 1116-1120
-
-
Ono, Y.1
Kikkawa, U.2
Ogita, K.3
-
41
-
-
0030721001
-
Isoenzymes of protein kinase C: Differential involvement in apoptosis and pathogenesis
-
Deacon EM, Pongracz J, Griffiths G, Lord JM. Isoenzymes of protein kinase C: differential involvement in apoptosis and pathogenesis. Mol Pathol 1997;50:124-31.
-
(1997)
Mol Pathol
, vol.50
, pp. 124-131
-
-
Deacon, E.M.1
Pongracz, J.2
Griffiths, G.3
Lord, J.M.4
-
42
-
-
4143099402
-
Antisense targeting protein kinase C α and β1 inhibits gastric carcinogenesis
-
Jiang XH, Tu SP, Cui JT, et al. Antisense targeting protein kinase C α and β1 inhibits gastric carcinogenesis. Cancer Res 2004;64:5787-94.
-
(2004)
Cancer Res
, vol.64
, pp. 5787-5794
-
-
Jiang, X.H.1
Tu, S.P.2
Cui, J.T.3
-
43
-
-
0034056322
-
Overexpression of protein kinase C-β1 isoenzyme suppresses indomethacin-induced apoptosis in gastric epithelial cells
-
Zhu GH, Wong BC, Slosberg ED, et al. Overexpression of protein kinase C-β1 isoenzyme suppresses indomethacin-induced apoptosis in gastric epithelial cells. Gastroenterology 2000;118:507-14.
-
(2000)
Gastroenterology
, vol.118
, pp. 507-514
-
-
Zhu, G.H.1
Wong, B.C.2
Slosberg, E.D.3
-
44
-
-
0037026663
-
Novel target for induction of apoptosis by cyclo-oxygenase-2 inhibitor SC-236 through a protein kinase C-β(1)-dependent pathway
-
Jiang XH, Lam SK, Lin MC, et al. Novel target for induction of apoptosis by cyclo-oxygenase-2 inhibitor SC-236 through a protein kinase C-β(1)-dependent pathway. Oncogene 2002;21:6113-22.
-
(2002)
Oncogene
, vol.21
, pp. 6113-6122
-
-
Jiang, X.H.1
Lam, S.K.2
Lin, M.C.3
-
45
-
-
20044392672
-
Mining for regulatory programs in the cancer transcriptome
-
Rhodes DR, Kalyana-Sundaram S, Mahavisno V, Barrette TR, Ghosh D, Chinnaiyan AM. Mining for regulatory programs in the cancer transcriptome. Nat Genet 2005;37:579-83.
-
(2005)
Nat Genet
, vol.37
, pp. 579-583
-
-
Rhodes, D.R.1
Kalyana-Sundaram, S.2
Mahavisno, V.3
Barrette, T.R.4
Ghosh, D.5
Chinnaiyan, A.M.6
-
46
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie T, Perou CM, Tibshirani R, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A 2001;98:10869-74.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
-
47
-
-
13044304179
-
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
-
Perou CM, Jeffrey SS, van de Rijn M, et al. Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc Natl Acad Sci U S A 1999;96:9212-7.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 9212-9217
-
-
Perou, C.M.1
Jeffrey, S.S.2
Van De Rijn, M.3
-
48
-
-
18244409687
-
Gene expression profiling predicts clinical outcome of breast cancer
-
van't Veer LJ, Dai H, van de Vijver MJ, et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 2002;415:530-6.
-
(2002)
Nature
, vol.415
, pp. 530-536
-
-
Van't Veer, L.J.1
Dai, H.2
Van De Vijver, M.J.3
|