Thrombin induces expression of FGF-2 via activation of PI3K-Akt-Fra-1 signaling axis leading to DNA synthesis and motility in vascular smooth muscle cells

American Journal of Physiology - Cell Physiology

Volumn 290, Issue 1, 2006, Pages

  Cao, Huiqing ^a   Dronadula, Nagadhara ^a   Rao, Gadiparthi N ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; FIBROBLAST GROWTH FACTOR 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; THROMBIN; TRANSCRIPTION FACTOR FRA 1; EPIDERMAL GROWTH FACTOR RECEPTOR; HEMOSTATIC AGENT; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN C FOS; PROTEIN KINASE; RIBOSOMAL PROTEIN S6 KINASE, 70KD, POLYPEPTIDE 1; S6 KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MIGRATION; CELL MOTILITY; DNA SYNTHESIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; ANIMAL; CELL MOTION; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION; GENETICS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; THORACIC AORTA;

ADENOVIRIDAE; ANIMALIA; MAMMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; AORTA, THORACIC; CELL MOVEMENT; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION; HEMOSTATICS; MALE; MUSCLE, SMOOTH, VASCULAR; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, EPIDERMAL GROWTH FACTOR; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; THROMBIN;

EID: 33644822656     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00284.2005     Document Type: Article

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