메뉴 건너뛰기




Volumn 21, Issue 9, 2011, Pages 607-613

PharmGKB Summary: Very important pharmacogene information for PTGS2

Author keywords

coxibs; cyclooxygenase 2; non steroidal anti inflammatory drugs; pharmacogenomics; PTGS2; rs20417; rs5275; rs689466

Indexed keywords

ACETYLSALICYLIC ACID; CAPECITABINE; CELECOXIB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DICLOFENAC; ETODOLAC; ETORICOXIB; FLURBIPROFEN; IBUPROFEN; INDOMETACIN; LUMIRACOXIB; MELOXICAM; NONSTEROID ANTIINFLAMMATORY AGENT; OXALIPLATIN; ROFECOXIB; VALDECOXIB;

EID: 80051793666     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0b013e3283415515     Document Type: Review
Times cited : (14)

References (79)
  • 1
    • 77951909982 scopus 로고    scopus 로고
    • Emotion recollected in tranquility: Lessons learned from the COX-2 saga
    • Grosser T, Yu Y, Fitzgerald GA. Emotion recollected in tranquility: lessons learned from the COX-2 saga. Annu Rev Med 2010;61:17-33.
    • (2010) Annu Rev Med , vol.61 , pp. 17-33
    • Grosser, T.1    Yu, Y.2    Fitzgerald, G.A.3
  • 2
    • 5644254327 scopus 로고    scopus 로고
    • Withdrawal of Vioxx casts a shadow over COX-2 inhibitors
    • DOI 10.1126/science.306.5695.384
    • Couzin J. Drug safety: withdrawal of Vioxx casts a shadow over COX-2 inhibitors. Science 2004;306:384-385. (Pubitemid 39372409)
    • (2004) Science , vol.306 , Issue.5695 , pp. 384-385
    • Couzin, J.1
  • 3
    • 66349127141 scopus 로고    scopus 로고
    • Cyclooxygenases: Structural and functional insights
    • Rouzer CA, Marnett LJ. Cyclooxygenases: structural and functional insights. J Lipid Res 2009;50(Suppl):S29-S34.
    • (2009) J Lipid Res , vol.50 , Issue.SUPPL.
    • Rouzer, C.A.1    Marnett, L.J.2
  • 6
    • 0036157485 scopus 로고    scopus 로고
    • Many actions of cyclooxygenase-2 in cellular dynamics and in cancer
    • DOI 10.1002/jcp.10068
    • Cao Y, Prescott SM. Many actions of cyclooxygenase-2 in cellular dynamics and in cancer. J Cell Physiol 2002;190:279-286. (Pubitemid 34111968)
    • (2002) Journal of Cellular Physiology , vol.190 , Issue.3 , pp. 279-286
    • Cao, Y.1    Prescott, S.M.2
  • 7
    • 4143124753 scopus 로고    scopus 로고
    • Signal transduction pathways regulating cyclooxygenase-2 expression: Potential molecular targets for chemoprevention
    • Chun KS, Surh YJ. Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention. Biochem Pharmacol 2004;68:1089-1100.
    • (2004) Biochem Pharmacol , vol.68 , pp. 1089-1100
    • Chun, K.S.1    Surh, Y.J.2
  • 8
    • 70449706453 scopus 로고    scopus 로고
    • Posttranscriptional and posttranslational determinants of cyclooxygenase expression
    • Mbonye UR, Song I. Posttranscriptional and posttranslational determinants of cyclooxygenase expression. BMB Rep 2009;42:552-560.
    • (2009) BMB Rep , vol.42 , pp. 552-560
    • Mbonye, U.R.1    Song, I.2
  • 9
    • 33947305279 scopus 로고    scopus 로고
    • Functional Antagonism Between RNA Binding Proteins HuR and CUGBP2 Determines the Fate of COX-2 mRNA Translation
    • DOI 10.1053/j.gastro.2006.12.031, PII S0016508506026813
    • Sureban SM, Murmu N, Rodriguez P, May R, Maheshwari R, Dieckgraefe BK, et al. Functional antagonism between RNA binding proteins HuR and CUGBP2 determines the fate of COX-2 mRNA translation. Gastroenterology 2007;132:1055-1065. (Pubitemid 46440864)
    • (2007) Gastroenterology , vol.132 , Issue.3 , pp. 1055-1065
    • Sureban, S.M.1    Murmu, N.2    Rodriguez, P.3    May, R.4    Maheshwari, R.5    Dieckgraefe, B.K.6    Houchen, C.W.7    Anant, S.8
  • 10
    • 0035138742 scopus 로고    scopus 로고
    • Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38
    • DOI 10.1128/MCB.21.3.771-780.2001
    • Lasa M, Brook M, Saklatvala J, Clark AR. Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38. Mol Cell Biol 2001;21:771-780. (Pubitemid 32104726)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.3 , pp. 771-780
    • Lasa, M.1    Brook, M.2    Saklatvala, J.3    Clark, A.R.4
  • 14
    • 70349235481 scopus 로고    scopus 로고
    • Variability in the response to cyclooxygenase inhibitors: Toward the individualization of nonsteroidal anti-inflammatory drug therapy
    • Grosser T. Variability in the response to cyclooxygenase inhibitors: toward the individualization of nonsteroidal anti-inflammatory drug therapy. J Investig Med 2009;57:709-716.
    • (2009) J Investig Med , vol.57 , pp. 709-716
    • Grosser, T.1
  • 15
    • 33744495376 scopus 로고    scopus 로고
    • Cyclooxygenase 2: Understanding the pathophysiological role through genetically altered mouse models
    • DOI 10.2741/2016
    • Martin Sanz P, Hortelano S, Bosca L, Casado M. Cyclooxygenase 2: understanding the pathophysiological role through genetically altered mouse models. Front Biosci 2006;11:2876-2888. (Pubitemid 43800381)
    • (2006) Frontiers in Bioscience , vol.11 , Issue.SUPPL. 3 , pp. 2876-2888
    • Sanz, P.M.1    Hortelano, S.2    Bosca, L.3    Casado, M.4
  • 16
    • 33845298303 scopus 로고    scopus 로고
    • A novel genetic model of selective COX-2 inhibition: Comparison with COX-2 null mice
    • DOI 10.1016/j.prostaglandins.2006.05.021, PII S1098882306000621, Eicosanoid-Mediated Regulation of Vascular and Renal Function
    • Yu Y, Funk CD. A novel genetic model of selective COX-2 inhibition: comparison with COX-2 null mice. Prostaglandins Other Lipid Mediat 2007;82:77-84. (Pubitemid 44880167)
    • (2007) Prostaglandins and Other Lipid Mediators , vol.82 , Issue.1-4 , pp. 77-84
    • Yu, Y.1    Funk, C.D.2
  • 19
    • 33646415952 scopus 로고    scopus 로고
    • Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function
    • Cheng Y, Wang M, Yu Y, Lawson J, Funk CD, Fitzgerald GA. Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function. J Clin Invest 2006;116:1391-1399.
    • (2006) J Clin Invest , vol.116 , pp. 1391-1399
    • Cheng, Y.1    Wang, M.2    Yu, Y.3    Lawson, J.4    Funk, C.D.5    Fitzgerald, G.A.6
  • 20
    • 76349108251 scopus 로고    scopus 로고
    • Cyclooxygenase-2-dependent prostacyclin formation and blood pressure homeostasis: Targeted exchange of cyclooxygenase isoforms in mice
    • Yu Y, Stubbe J, Ibrahim S, Song WL, Symth EM, Funk CD, et al. Cyclooxygenase-2-dependent prostacyclin formation and blood pressure homeostasis: targeted exchange of cyclooxygenase isoforms in mice. Circ Res 2010;106:337-345.
    • (2010) Circ Res , vol.106 , pp. 337-345
    • Yu, Y.1    Stubbe, J.2    Ibrahim, S.3    Song, W.L.4    Symth, E.M.5    Funk, C.D.6
  • 21
    • 0028818913 scopus 로고
    • Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II
    • Dinchuk JE, Car BD, Focht RJ, Johnston JJ, Jaffee BD, Covington MB, et al. Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II. Nature 1995;378:406-409.
    • (1995) Nature , vol.378 , pp. 406-409
    • Dinchuk, J.E.1    Car, B.D.2    Focht, R.J.3    Johnston, J.J.4    Jaffee, B.D.5    Covington, M.B.6
  • 23
    • 0030702122 scopus 로고    scopus 로고
    • Multiple female reproductive failures in cyclooxygenase 2-deficient mice
    • DOI 10.1016/S0092-8674(00)80402-X
    • Lim H, Paria BC, Das SK, Dinchuk JE, Langenbach R, Trzaskos JM, et al. Multiple female reproductive failures in cyclooxygenase-2-deficient mice. Cell 1997;91:197-208. (Pubitemid 27456387)
    • (1997) Cell , vol.91 , Issue.2 , pp. 197-208
    • Lim, H.1    Paria, B.C.2    Das, S.K.3    Dinchuk, J.E.4    Langenbach, R.5    Trzaskos, J.M.6    Dey, S.K.7
  • 25
    • 58149215969 scopus 로고    scopus 로고
    • Cyclooxygenase polymorphisms in gastric and colorectal carcinogenesis: Are conclusive results available?
    • Pereira C, Medeiros RM, Dinis-Ribeiro MJ. Cyclooxygenase polymorphisms in gastric and colorectal carcinogenesis: are conclusive results available? Eur J Gastroenterol Hepatol 2009;21:76-91.
    • (2009) Eur J Gastroenterol Hepatol , vol.21 , pp. 76-91
    • Pereira, C.1    Medeiros, R.M.2    Dinis-Ribeiro, M.J.3
  • 26
    • 70249084836 scopus 로고    scopus 로고
    • PTGS2-899G>C and prostate cancer risk: A population-based nested case-control study (ProtecT) and a systematic review with metaanalysis
    • Murad A, Lewis SJ, Smith GD, Collin SM, Chen L, Hamdy FC, et al. PTGS2-899G>C and prostate cancer risk: a population-based nested case-control study (ProtecT) and a systematic review with metaanalysis. Prostate Cancer Prostatic Dis 2009;12:296-300.
    • (2009) Prostate Cancer Prostatic Dis , vol.12 , pp. 296-300
    • Murad, A.1    Lewis, S.J.2    Smith, G.D.3    Collin, S.M.4    Chen, L.5    Hamdy, F.C.6
  • 27
    • 77950886696 scopus 로고    scopus 로고
    • PTGS2 and IL6 genetic variation and risk of breast and prostate cancer: Results from the Breast and Prostate Cancer Cohort Consortium (BPC3)
    • Dossus L, Kaaks R, Canzian F, Albanes D, Berndt SI, Boeing H, et al. PTGS2 and IL6 genetic variation and risk of breast and prostate cancer: results from the Breast and Prostate Cancer Cohort Consortium (BPC3). Carcinogenesis 2010;31:455-461.
    • (2010) Carcinogenesis , vol.31 , pp. 455-461
    • Dossus, L.1    Kaaks, R.2    Canzian, F.3    Albanes, D.4    Berndt, S.I.5    Boeing, H.6
  • 28
    • 77049123443 scopus 로고    scopus 로고
    • Associations between COX-2 polymorphisms, blood cholesterol and risk of acute coronary syndrome
    • Vogel U, Segel S, Dethlefsen C, Tjonneland A, Saber AT, Wallin H, et al. Associations between COX-2 polymorphisms, blood cholesterol and risk of acute coronary syndrome. Atherosclerosis 2010;209:155-162.
    • (2010) Atherosclerosis , vol.209 , pp. 155-162
    • Vogel, U.1    Segel, S.2    Dethlefsen, C.3    Tjonneland, A.4    Saber, A.T.5    Wallin, H.6
  • 30
    • 37549011400 scopus 로고    scopus 로고
    • Cyclooxygenase polymorphisms and risk of cardiovascular events: The Atherosclerosis Risk in Communities (ARIC) study
    • Lee CR, North KE, Bray MS, Couper DJ, Heiss G, Zeldin DC. Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study. Clin Pharmacol Ther 2008;83:52-60.
    • (2008) Clin Pharmacol Ther , vol.83 , pp. 52-60
    • Lee, C.R.1    North, K.E.2    Bray, M.S.3    Couper, D.J.4    Heiss, G.5    Zeldin, D.C.6
  • 31
    • 38349127895 scopus 로고    scopus 로고
    • Increased risks of incident stroke associated with the cyclooxygenase 2 (COX-2) G-765C polymorphism in African-Americans: The Atherosclerosis Risk in Communities Study
    • Kohsaka S, Volcik KA, Folsom AR, Wu KK, Ballantyne CM, Willerson JT, et al. Increased risks of incident stroke associated with the cyclooxygenase 2 (COX-2) G-765C polymorphism in African-Americans: the Atherosclerosis Risk in Communities Study. Atherosclerosis 2008;196:926-930.
    • (2008) Atherosclerosis , vol.196 , pp. 926-930
    • Kohsaka, S.1    Volcik, K.A.2    Folsom, A.R.3    Wu, K.K.4    Ballantyne, C.M.5    Willerson, J.T.6
  • 32
    • 33646827887 scopus 로고    scopus 로고
    • Protective effect of the G-765C COX-2 polymorphism on subclinical atherosclerosis and inflammatory markers in asymptomatic subjects with cardiovascular risk factors
    • DOI 10.1016/j.cca.2005.12.019, PII S0009898105007254
    • Orbe J, Beloqui O, Rodriguez JA, Belzunce MS, Roncal C, Paramo JA. Protective effect of the G-765C COX-2 polymorphism on subclinical atherosclerosis and inflammatory markers in asymptomatic subjects with cardiovascular risk factors. Clin Chim Acta 2006;368:138-143. (Pubitemid 43776030)
    • (2006) Clinica Chimica Acta , vol.368 , Issue.1-2 , pp. 138-143
    • Orbe, J.1    Beloqui, O.2    Rodriguez, J.A.3    Belzunce, M.S.4    Roncal, C.5    Paramo, J.A.6
  • 34
    • 77049112046 scopus 로고    scopus 로고
    • Role of cyclooxygenase-2 and 5-lipoxygenase polymorphisms in Alzheimer's disease in a population from northern Italy: Implication for pharmacogenomics
    • Listi F, Caruso C, Lio D, Colonna-Romano G, Chiappelli M, Licastro F, et al. Role of cyclooxygenase-2 and 5-lipoxygenase polymorphisms in Alzheimer's disease in a population from northern Italy: implication for pharmacogenomics. J Alzheimers Dis 2010;19:551-557.
    • (2010) J Alzheimers Dis , vol.19 , pp. 551-557
    • Listi, F.1    Caruso, C.2    Lio, D.3    Colonna-Romano, G.4    Chiappelli, M.5    Licastro, F.6
  • 35
    • 42649138585 scopus 로고    scopus 로고
    • Association of prostaglandin-endoperoxide synthase 2 (PTGS2) polymorphisms and Alzheimer's disease in Chinese
    • DOI 10.1016/j.neurobiolaging.2006.12.011, PII S0197458006004702
    • Ma SL, Tang NL, Zhang YP, Ji LD, Tam CW, Lui VW, et al. Association of prostaglandin-endoperoxide synthase 2 (PTGS2) polymorphisms and Alzheimer's disease in Chinese. Neurobiol Aging 2008;29:856-860. (Pubitemid 351601895)
    • (2008) Neurobiology of Aging , vol.29 , Issue.6 , pp. 856-860
    • Ma, S.L.1    Tang, N.L.S.2    Zhang, Y.P.3    Ji, L.-d.4    Tam, C.W.C.5    Lui, V.W.C.6    Chiu, H.F.K.7    Lam, L.C.W.8
  • 36
    • 32244441755 scopus 로고    scopus 로고
    • The cyclooxygenase 2-765 C promoter allele is a protective factor for Alzheimer's disease
    • DOI 10.1016/j.neulet.2005.10.090, PII S0304394005012723
    • Abdullah L, Ait-Ghezala G, Crawford F, Crowell TA, Barker WW, Duara R, et al. The cyclooxygenase 2-765 C promoter allele is a protective factor for Alzheimer's disease. Neurosci Lett 2006;395:240-243. (Pubitemid 43213153)
    • (2006) Neuroscience Letters , vol.395 , Issue.3 , pp. 240-243
    • Abdullah, L.1    Ait-Ghezala, G.2    Crawford, F.3    Crowell, T.A.4    Barker, W.W.5    Duara, R.6    Mullan, M.7
  • 37
    • 44249093486 scopus 로고    scopus 로고
    • Cyclooxygenase-2 gene polymorphisms in an Australian population: Association of the -1195G > A promoter polymorphism with mild asthma
    • DOI 10.1111/j.1365-2222.2008.02986.x
    • Shi J, Misso NL, Kedda MA, Horn J, Welch MD, Duffy DL, et al. Cyclooxygenase-2 gene polymorphisms in an Australian population: association of the-1195G > A promoter polymorphism with mild asthma. Clin Exp Allergy 2008;38:913-920. (Pubitemid 351725859)
    • (2008) Clinical and Experimental Allergy , vol.38 , Issue.6 , pp. 913-920
    • Shi, J.1    Misso, N.L.2    Kedda, M.-A.3    Horn, J.4    Welch, M.D.5    Duffy, D.L.6    Williams, C.7    Thompson, P.J.8
  • 39
    • 9244234422 scopus 로고    scopus 로고
    • A functional polymorphism in the promoter region of the cyclooxygenase-2 gene is not associated with asthma and atopy in an Australian population
    • DOI 10.1111/j.1365-2222.2004.02094.x
    • Shi J, Misso NL, Duffy DL, Thompson PJ, Kedda MA. A functional polymorphism in the promoter region of the cyclooxygenase-2 gene is not associated with asthma and atopy in an Australian population. Clin Exp Allergy 2004;34:1714-1718. (Pubitemid 39551524)
    • (2004) Clinical and Experimental Allergy , vol.34 , Issue.11 , pp. 1714-1718
    • Shi, J.1    Misso, N.L.2    Duffy, D.L.3    Thompson, P.J.4    Kedda, M.-A.5
  • 40
    • 4344568553 scopus 로고    scopus 로고
    • -765C in bronchial asthma
    • DOI 10.1016/j.jaci.2004.05.030, PII S0091674904014952
    • Szczeklik W, Sanak M, Szczeklik A. Functional effects and gender association of COX-2 gene polymorphism G-765C in bronchial asthma. J Allergy Clin Immunol 2004;114:248-253. (Pubitemid 39119020)
    • (2004) Journal of Allergy and Clinical Immunology , vol.114 , Issue.2 , pp. 248-253
    • Szczeklik, W.1    Sanak, M.2    Szczeklik, A.3
  • 41
    • 33750485335 scopus 로고    scopus 로고
    • Cyclooxygenase-2 polymorphisms and risk of systemic lupus erythematosus in Koreans
    • DOI 10.1007/s00296-006-0162-z
    • Her MY, El-Sohemy A, Cornelis MC, Kim TH, Bae SC. Cyclooxygenase-2 polymorphisms and risk of systemic lupus erythematosus in Koreans. Rheumatol Int 2006;27:1-5. (Pubitemid 44655742)
    • (2006) Rheumatology International , vol.27 , Issue.1 , pp. 1-5
    • Her, M.-Y.1    El-Sohemy, A.2    Cornelis, M.C.3    Kim, T.-H.4    Bae, S.-C.5
  • 44
    • 44449153906 scopus 로고    scopus 로고
    • Genome-wide association scan identifies a prostaglandinendoperoxide synthase 2 variant involved in risk of knee osteoarthritis
    • Valdes AM, Loughlin J, Timms KM, van Meurs JJ, Southam L, Wilson SG, et al. Genome-wide association scan identifies a prostaglandinendoperoxide synthase 2 variant involved in risk of knee osteoarthritis. Am J Hum Genet 2008;82:1231-1240.
    • (2008) Am J Hum Genet , vol.82 , pp. 1231-1240
    • Valdes, A.M.1    Loughlin, J.2    Timms, K.M.3    Van Meurs, J.J.4    Southam, L.5    Wilson, S.G.6
  • 45
    • 0141955279 scopus 로고    scopus 로고
    • Association of a promoter variant in the inducible cyclooxygenase-2 gene (PTGS2) with type 2 diabetes mellitus in Pima Indians
    • DOI 10.1007/s00439-003-1000-y
    • Konheim YL, Wolford JK. Association of a promoter variant in the inducible cyclooxygenase-2 gene (PTGS2) with type 2 diabetes mellitus in Pima Indians. Hum Genet 2003;113:377-381. (Pubitemid 37254241)
    • (2003) Human Genetics , vol.113 , Issue.5 , pp. 377-381
    • Konheim, Y.L.1    Wolford, J.K.2
  • 47
    • 60249090143 scopus 로고    scopus 로고
    • Common single nucleotide polymorphisms in cyclooxygenase-2 and risk of severe chronic periodontitis in a Chinese population
    • Xie CJ, Xiao LM, Fan WH, Xuan DY, Zhang JC. Common single nucleotide polymorphisms in cyclooxygenase-2 and risk of severe chronic periodontitis in a Chinese population. J Clin Periodontol 2009;36:198-203.
    • (2009) J Clin Periodontol , vol.36 , pp. 198-203
    • Xie, C.J.1    Xiao, L.M.2    Fan, W.H.3    Xuan, D.Y.4    Zhang, J.C.5
  • 48
    • 33646205060 scopus 로고    scopus 로고
    • Genetically mediated interindividual variation in analgesic responses to cyclooxygenase inhibitory drugs
    • Lee YS, Kim H, Wu TX, Wang XM, Dionne RA. Genetically mediated interindividual variation in analgesic responses to cyclooxygenase inhibitory drugs. Clin Pharmacol Ther 2006;79:407-418.
    • (2006) Clin Pharmacol Ther , vol.79 , pp. 407-418
    • Lee, Y.S.1    Kim, H.2    Wu, T.X.3    Wang, X.M.4    Dionne, R.A.5
  • 51
    • 2642569348 scopus 로고    scopus 로고
    • Interaction between cyclooxygenose-2 gene polymorphism and dietary n-6 polyunsaturated fatty acids on colon cancer risk: The Singapore Chinese Health Study
    • Koh WP, Yuan JM, van den Berg D, Lee HP, Yu MC. Interaction between cyclooxygenase-2 gene polymorphism and dietary n-6 polyunsaturated fatty acids on colon cancer risk: the Singapore Chinese Health Study. Br J Cancer 2004;90:1760-1764. (Pubitemid 38725648)
    • (2004) British Journal of Cancer , vol.90 , Issue.9 , pp. 1760-1764
    • Koh, W.-P.1    Yuan, J.-M.2    Van Den Berg, D.3    Lee, H.-P.4    Yu, M.C.5
  • 52
    • 13844266136 scopus 로고    scopus 로고
    • Colorectal adenoma risk is modified by the interplay between polymorphisms in arachidonic acid pathway genes and fish consumption
    • DOI 10.1093/carcin/bgh336
    • Siezen CL, van Leeuwen AI, Kram NR, Luken ME, van Kranen HJ, Kampman E. Colorectal adenoma risk is modified by the interplay between polymorphisms in arachidonic acid pathway genes and fish consumption. Carcinogenesis 2005;26:449-457. (Pubitemid 40246567)
    • (2005) Carcinogenesis , vol.26 , Issue.2 , pp. 449-457
    • Siezen, C.L.E.1    Van Leeuwen, A.I.M.2    Kram, N.R.3    Luken, M.E.M.4    Van Kranen, H.J.5    Kampman, E.6
  • 53
    • 65249182124 scopus 로고    scopus 로고
    • Dietary omega-3 fatty acids, cyclooxygenase-2 genetic variation, and aggressive prostate cancer risk
    • Fradet V, Cheng I, Casey G, Witte JS. Dietary omega-3 fatty acids, cyclooxygenase-2 genetic variation, and aggressive prostate cancer risk. Clin Cancer Res 2009;15:2559-2566.
    • (2009) Clin Cancer Res , vol.15 , pp. 2559-2566
    • Fradet, V.1    Cheng, I.2    Casey, G.3    Witte, J.S.4
  • 55
    • 58649110224 scopus 로고    scopus 로고
    • Polymorphisms cyclooxygenase-2-765G>C and interleukin-6-174G>C are associated with serum inflammation markers in a high cardiovascular risk population and do not modify the response to a Mediterranean diet supplemented with virgin olive oil or nuts
    • Corella D, Gonzalez JI, Bullo M, Carrasco P, Portoles O, Diez-Espino J, et al. Polymorphisms cyclooxygenase-2-765G>C and interleukin-6-174G>C are associated with serum inflammation markers in a high cardiovascular risk population and do not modify the response to a Mediterranean diet supplemented with virgin olive oil or nuts. J Nutr 2009;139:128-134.
    • (2009) J Nutr , vol.139 , pp. 128-134
    • Corella, D.1    Gonzalez, J.I.2    Bullo, M.3    Carrasco, P.4    Portoles, O.5    Diez-Espino, J.6
  • 57
    • 0036790471 scopus 로고    scopus 로고
    • Common promoter variant in cyclooxygenase-2 represses gene expression: Evidence of role in acute-phase inflammatory response
    • Papafili A, Hill MR, Brull DJ, McAnulty RJ, Marshall RP, Humphries SE, et al. Common promoter variant in cyclooxygenase-2 represses gene expression: evidence of role in acute-phase inflammatory response. Arterioscler Thromb Vasc Biol 2002;22:1631-1636.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1631-1636
    • Papafili, A.1    Hill, M.R.2    Brull, D.J.3    McAnulty, R.J.4    Marshall, R.P.5    Humphries, S.E.6
  • 59
    • 16844364790 scopus 로고    scopus 로고
    • PTGS2 (COX-2) -765G > C promoter variant reduces risk of colorectal adenoma among nonusers of nonsteroidal anti-inflammatory drugs
    • DOI 10.1158/1055-9965.EPI-04-0510
    • Ulrich CM, Whitton J, Yu JH, Sibert J, Sparks R, Potter JD, et al. PTGS2 (COX-2)-765G > C promoter variant reduces risk of colorectal adenoma among nonusers of nonsteroidal anti-inflammatory drugs. Cancer Epidemiol Biomarkers Prev 2005;14:616-619. (Pubitemid 40489204)
    • (2005) Cancer Epidemiology Biomarkers and Prevention , vol.14 , Issue.3 , pp. 616-619
    • Ulrich, C.M.1    Whitton, J.2    Yu, J.-H.3    Sibert, J.4    Sparks, R.5    Potter, J.D.6    Bigler, J.7
  • 60
    • 33644876453 scopus 로고    scopus 로고
    • SNP500Cancer: A public resource for sequence validation, assay development, and frequency analysis for genetic variation in candidate genes
    • Packer BR, Yeager M, Burdett L, Welch R, Beerman M, Qi L, et al. SNP500Cancer: a public resource for sequence validation, assay development, and frequency analysis for genetic variation in candidate genes. Nucleic Acids Res 2006;34:D617-D621.
    • (2006) Nucleic Acids Res , vol.34
    • Packer, B.R.1    Yeager, M.2    Burdett, L.3    Welch, R.4    Beerman, M.5    Qi, L.6
  • 62
    • 77950989929 scopus 로고    scopus 로고
    • Functional rs20417 SNP (-765G > C) of cyclooxygenase-2 gene does not predict the risk of recurrence of ischemic events in coronary patients: Results of a 7-year prospective study
    • Montali A, Barilla F, Tanzilli G, Vestri A, Fraioli A, Gaudio C, et al. Functional rs20417 SNP (-765G > C) of cyclooxygenase-2 gene does not predict the risk of recurrence of ischemic events in coronary patients: results of a 7-year prospective study. Cardiology 2010;115:236-242.
    • (2010) Cardiology , vol.115 , pp. 236-242
    • Montali, A.1    Barilla, F.2    Tanzilli, G.3    Vestri, A.4    Fraioli, A.5    Gaudio, C.6
  • 63
    • 62649173099 scopus 로고    scopus 로고
    • Association of polymorphisms in cyclooxygenase (COX)-2 with coronary and carotid calcium in the Diabetes Heart Study
    • Rudock ME, Liu Y, Ziegler JT, Allen SG, Lehtinen AB, Freedman BI, et al. Association of polymorphisms in cyclooxygenase (COX)-2 with coronary and carotid calcium in the Diabetes Heart Study. Atherosclerosis 2009;203:459-465.
    • (2009) Atherosclerosis , vol.203 , pp. 459-465
    • Rudock, M.E.1    Liu, Y.2    Ziegler, J.T.3    Allen, S.G.4    Lehtinen, A.B.5    Freedman, B.I.6
  • 64
    • 70350503403 scopus 로고    scopus 로고
    • The influence of COX-2 single nucleotide polymorphisms on abdominal aortic aneurysm development and the associated inflammation
    • Badger SA, Soong CV, Young IS, McGinty A, Mercer C, Hughes AE. The influence of COX-2 single nucleotide polymorphisms on abdominal aortic aneurysm development and the associated inflammation. Angiology 2009;60:576-581.
    • (2009) Angiology , vol.60 , pp. 576-581
    • Badger, S.A.1    Soong, C.V.2    Young, I.S.3    McGinty, A.4    Mercer, C.5    Hughes, A.E.6
  • 65
    • 77953543706 scopus 로고    scopus 로고
    • Current evidence on the relationship between polymorphisms in the COX-2 gene and breast cancer risk: A meta-analysis
    • Yu KD, Chen AX, Yang C, Qiu LX, Fan L, Xu WH, et al. Current evidence on the relationship between polymorphisms in the COX-2 gene and breast cancer risk: a meta-analysis. Breast Cancer Res Treat 2009;122:251-257.
    • (2009) Breast Cancer Res Treat , vol.122 , pp. 251-257
    • Yu, K.D.1    Chen, A.X.2    Yang, C.3    Qiu, L.X.4    Fan, L.5    Xu, W.H.6
  • 67
    • 63449084313 scopus 로고    scopus 로고
    • Cyclooxygenase-2 gene polymorphisms reduce the risk of oral premalignant lesions
    • Pu X, Lippman SM, Yang H, Lee JJ, Wu X. Cyclooxygenase-2 gene polymorphisms reduce the risk of oral premalignant lesions. Cancer 2009;115:1498-1506.
    • (2009) Cancer , vol.115 , pp. 1498-1506
    • Pu, X.1    Lippman, S.M.2    Yang, H.3    Lee, J.J.4    Wu, X.5
  • 70
    • 12844269195 scopus 로고    scopus 로고
    • Biological assessment of aspirin efficacy on healthy individuals: Heterogeneous response or aspirin failure?
    • DOI 10.1161/01.STR.0000151362.65339.f9
    • Gonzalez-Conejero R, Rivera J, Corral J, Acuna C, Guerrero JA, Vicente V. Biological assessment of aspirin efficacy on healthy individuals: heterogeneous response or aspirin failure? Stroke 2005;36:276-280. (Pubitemid 40170808)
    • (2005) Stroke , vol.36 , Issue.2 , pp. 276-280
    • Gonzalez-Conejero, R.1    Rivera, J.2    Corral, J.3    Acuna, C.4    Guerrero, J.A.5    Vicente, V.6
  • 72
    • 55549083196 scopus 로고    scopus 로고
    • Common polymorphisms of cyclooxygenase-2 and prostaglandin E2 receptor and increased risk for acute coronary syndrome in coronary artery disease
    • Szczeklik W, Sanak M, Rostoff P, Piwowarska W, Jakiela B, Szczeklik A. Common polymorphisms of cyclooxygenase-2 and prostaglandin E2 receptor and increased risk for acute coronary syndrome in coronary artery disease. Thromb Haemost 2008;100:893-898.
    • (2008) Thromb Haemost , vol.100 , pp. 893-898
    • Szczeklik, W.1    Sanak, M.2    Rostoff, P.3    Piwowarska, W.4    Jakiela, B.5    Szczeklik, A.6
  • 73
    • 69049117222 scopus 로고    scopus 로고
    • Prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) 8473T>C polymorphism associated with prognosis for patients with colorectal cancer treated with capecitabine and oxaliplatin
    • Kim JG, Chae YS, Sohn SK, Moon JH, Ryoo HM, Bae SH, et al. Prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) 8473T>C polymorphism associated with prognosis for patients with colorectal cancer treated with capecitabine and oxaliplatin. Cancer Chemother Pharmacol 2009;64:953-960.
    • (2009) Cancer Chemother Pharmacol , vol.64 , pp. 953-960
    • Kim, J.G.1    Chae, Y.S.2    Sohn, S.K.3    Moon, J.H.4    Ryoo, H.M.5    Bae, S.H.6
  • 75
    • 65249112214 scopus 로고    scopus 로고
    • Interaction of cyclooxygenase-2 variants and smoking in pancreatic cancer: A possible role of nucleophosmin
    • Zhao D, Xu D, Zhang X, Wang L, Tan W, Guo Y, et al. Interaction of cyclooxygenase-2 variants and smoking in pancreatic cancer: a possible role of nucleophosmin. Gastroenterology 2009;136:1659-1668.
    • (2009) Gastroenterology , vol.136 , pp. 1659-1668
    • Zhao, D.1    Xu, D.2    Zhang, X.3    Wang, L.4    Tan, W.5    Guo, Y.6
  • 76
    • 2642524416 scopus 로고    scopus 로고
    • Genetic analysis of 22 candidate genes for hypertension in the Japanese population
    • DOI 10.1097/00004872-200406000-00012
    • Iwai N, Tago N, Yasui N, Kokubo Y, Inamoto N, Tomoike H, et al. Genetic analysis of 22 candidate genes for hypertension in the Japanese population. J Hypertens 2004;22:1119-1126. (Pubitemid 38721003)
    • (2004) Journal of Hypertension , vol.22 , Issue.6 , pp. 1119-1126
    • Iwai, N.1    Tago, N.2    Yasui, N.3    Kokubo, Y.4    Inamoto, N.5    Tomoike, H.6    Shioji, K.7
  • 77
    • 67549149329 scopus 로고    scopus 로고
    • New, long-term insights from the Adenoma Prevention with Celecoxib Trial on a promising but troubled class of drugs
    • Dubois RN. New, long-term insights from the Adenoma Prevention with Celecoxib Trial on a promising but troubled class of drugs. Cancer Prev Res (Phila) 2009;2:285-287.
    • (2009) Cancer Prev Res (Phila) , vol.2 , pp. 285-287
    • Dubois, R.N.1
  • 79
    • 36348932768 scopus 로고    scopus 로고
    • COX-2 inhibitors and cardiovascular risk
    • DOI 10.1097/FJC.0b013e318157f72d, PII 0000534420071100000002
    • Funk CD, FitzGerald GA. COX-2 inhibitors and cardiovascular risk. J Cardiovasc Pharmacol 2007;50:470-479. (Pubitemid 350146448)
    • (2007) Journal of Cardiovascular Pharmacology , vol.50 , Issue.5 , pp. 470-479
    • Funk, C.D.1    FitzGerald, G.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.