Multiple templates-based homology modeling enhances structure quality of AT1 receptor: Validation by molecular dynamics and antagonist docking

Journal of Molecular Modeling

Volumn 17, Issue 7, 2011, Pages 1565-1577

  Sokkar, Pandian ^a   Mohandass, Shylajanaciyar ^a   Ramachandran, Murugesan ^a  

^a MADURAI KAMARAJ UNIVERSITY   (India)

Author keywords

AT1 receptor; Explicit membrane; Homology modeling; I TASSER; Molecular docking; Molecular dynamics; Multiple templates

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN II; ANTIHYPERTENSIVE AGENT; CANDESARTAN; EPROSARTAN; IRBESARTAN; LOSARTAN; OLMESARTAN; RHODOPSIN; TELMISARTAN; VALSARTAN; WATER;

ANALYTIC METHOD; ARTICLE; BLOOD PRESSURE REGULATION; CARDIOVASCULAR DISEASE; CARDIOVASCULAR SYSTEM; CELL TYPE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG DESIGN; KIDNEY; MEDIATOR; MEMBRANE; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MONTE CARLO METHOD; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN STRUCTURE; RAMACHANDRAN PLOT ANALYSIS; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; WEB BROWSER;

AMINO ACID SEQUENCE; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; CATTLE; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN STABILITY; RECEPTOR, ANGIOTENSIN, TYPE 1; REPRODUCIBILITY OF RESULTS; RHODOPSIN; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

BOVINAE;

EID: 80051784951     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-010-0860-z     Document Type: Article

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