-
1
-
-
19944427850
-
Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype
-
DOI 10.1056/NEJMoa041974
-
Falini B, Mecucci C, Tiacci E, Alcalay M, Rosati R, Pasqualucci L et al. Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. N Engl J Med 2005;352:254-266. (Pubitemid 40110814)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.3
, pp. 254-266
-
-
Falini, B.1
Mecucci, C.2
Tiacci, E.3
Alcalay, M.4
Rosati, R.5
Pasqualucci, L.6
La Starza, R.7
Diverio, D.8
Colombo, E.9
Santucci, A.10
Bigerna, B.11
Pacini, R.12
Pucciarini, A.13
Liso, A.14
Vignetti, M.15
Fazi, P.16
Meani, N.17
Pettirossi, V.18
Saglio, G.19
Mandelli, F.20
Lo-Coco, F.21
Pelicci, P.-G.22
Martelli, M.F.23
more..
-
2
-
-
33846876123
-
+ AML): Biologic and clinical features
-
DOI 10.1182/blood-2006-07-012252
-
Falini B, Nicoletti I, Martelli MF, Mecucci C. Acute myeloid leukemia carrying cytoplasmic/mutated nucleophosmin (NPMc+ AML): biologic and clinical features. Blood 2007;109:874-885. (Pubitemid 46220630)
-
(2007)
Blood
, vol.109
, Issue.3
, pp. 874-885
-
-
Falini, B.1
Nicoletti, I.2
Martelli, M.F.3
Mecucci, C.4
-
3
-
-
28444473100
-
Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: Interaction with other gene mutations
-
DOI 10.1182/blood-2005-05-2164
-
Döhner K, Schlenk RF, Habdank M, Scholl C, Rücker FG, Corbacioglu A et al. Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations. Blood 2005;106:3740-3746. (Pubitemid 41739007)
-
(2005)
Blood
, vol.106
, Issue.12
, pp. 3740-3746
-
-
Dohner, K.1
Schlenk, R.F.2
Habdank, M.3
Scholl, C.4
Rucker, F.G.5
Corbacioglu, A.6
Bullinger, L.7
Frohling, S.8
Dohner, H.9
-
4
-
-
28444449081
-
Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype
-
DOI 10.1182/blood-2005-06-2248
-
Schnittger S, Schoch C, Kern W, Mecucci C, Tschulik C, Martelli MF et al. Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype. Blood 2005;106:3733-3739. (Pubitemid 41739006)
-
(2005)
Blood
, vol.106
, Issue.12
, pp. 3733-3739
-
-
Schnittger, S.1
Schoch, C.2
Kern, W.3
Mecucci, C.4
Tschulik, C.5
Martelli, M.F.6
Haferlach, T.7
Hiddemann, W.8
Falini, B.9
-
5
-
-
28444446313
-
Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): Association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance
-
DOI 10.1182/blood-2005-05-2168
-
Verhaak RG, Goudswaard CS, van Putten W, Bijl MA, Sanders MA, Hugens W et al. Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance. Blood 2005;106:3747-3754. (Pubitemid 41739008)
-
(2005)
Blood
, vol.106
, Issue.12
, pp. 3747-3754
-
-
Verhaak, R.G.W.1
Goudswaard, C.S.2
Van Putten, W.3
Bijl, M.A.4
Sanders, M.A.5
Hugens, W.6
Uitterlinden, A.G.7
Erpelinck, C.A.J.8
Delwel, R.9
Lowenberg, B.10
Valk, P.J.M.11
-
6
-
-
53249123632
-
-
4th edn. IARC press: Lyon
-
Swerdlow S, Campo E, Lee Harris N, Jaffe E, Pileri S, Stein H et al. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. 4th edn. IARC press: Lyon, 2008.
-
(2008)
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
-
-
Swerdlow, S.1
Campo, E.2
Lee Harris, N.3
Jaffe, E.4
Pileri, S.5
Stein, H.6
-
7
-
-
79251556241
-
Acute myeloid leukemia with mutated nucleophosmin (NPM1): Is it a distinct entity?
-
Falini B, Martelli MP, Bolli N, Sportoletti P, Liso A, Tiacci E et al. Acute myeloid leukemia with mutated nucleophosmin (NPM1): Is it a distinct entity? Blood 2011;117:1109-1120.
-
(2011)
Blood
, vol.117
, pp. 1109-1120
-
-
Falini, B.1
Martelli, M.P.2
Bolli, N.3
Sportoletti, P.4
Liso, A.5
Tiacci, E.6
-
8
-
-
0030451722
-
Internal tandem duplication of the flt3 gene found in acute myeloid leukemia
-
Nakao M, Yokota S, Iwai T, Kaneko H, Horiike S, Kashima K et al. Internal tandem duplication of the flt3 gene found in acute myeloid leukemia. Leukemia 1996;10:1911-1918. (Pubitemid 27019637)
-
(1996)
Leukemia
, vol.10
, Issue.12
, pp. 1911-1918
-
-
Nakao, M.1
Yokota, S.2
Iwai, T.3
Kaneko, H.4
Horiike, S.5
Kashima, K.6
Sonoda, Y.7
Fujimoto, T.8
Misawa, S.9
-
9
-
-
0035885955
-
The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: Analysis of 854 patients from the United Kingdom medical research council AML 10 and 12 trials
-
Kottaridis PD, Gale RE, Frew ME, Harrison G, Langabeer SE, Belton AA et al. The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials. Blood 2001;98:1752-1759.
-
(2001)
Blood
, vol.98
, pp. 1752-1759
-
-
Kottaridis, P.D.1
Gale, R.E.2
Frew, M.E.3
Harrison, G.4
Langabeer, S.E.5
Belton, A.A.6
-
10
-
-
0036659931
-
Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: Correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease
-
DOI 10.1182/blood.V100.1.59
-
Schnittger S, Schoch C, Dugas M, Kern W, Staib P, Wuchter C et al. Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease. Blood 2002;100:59-66. (Pubitemid 35177429)
-
(2002)
Blood
, vol.100
, Issue.1
, pp. 59-66
-
-
Schnittger, S.1
Schoch, C.2
Dugas, M.3
Kern, W.4
Staib, P.5
Wuchter, C.6
Loffler, H.7
Sauerland, C.M.8
Serve, H.9
Buchner, T.10
Haferlach, T.11
Hiddemann, W.12
-
11
-
-
0034598830
-
Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines
-
Hayakawa F, Towatari M, Kiyoi H, Tanimoto M, Kitamura T, Saito H et al. Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines. Oncogene 2000;19:624-631. (Pubitemid 30102913)
-
(2000)
Oncogene
, vol.19
, Issue.5
, pp. 624-631
-
-
Hayakawa, F.1
Towatari, M.2
Kiyoi, H.3
Tanimoto, M.4
Kitamura, T.5
Saito, H.6
Naoe, T.7
-
12
-
-
0034554796
-
Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways
-
Mizuki M, Fenski R, Halfter H, Matsumura I, Schmidt R, Müller C et al. Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways. Blood 2000;96:3907-3914.
-
(2000)
Blood
, vol.96
, pp. 3907-3914
-
-
Mizuki, M.1
Fenski, R.2
Halfter, H.3
Matsumura, I.4
Schmidt, R.5
Müller, C.6
-
13
-
-
70449362059
-
FLT3-ITD expression levels and their effect on STAT5 in AML with and without NPM mutations
-
Seedhouse CH, Pallis M, Grundy M, Shang S, Russell NH. FLT3-ITD expression levels and their effect on STAT5 in AML with and without NPM mutations. Br J Haematol 2009;147:653-661.
-
(2009)
Br J Haematol
, vol.147
, pp. 653-661
-
-
Seedhouse, C.H.1
Pallis, M.2
Grundy, M.3
Shang, S.4
Russell, N.H.5
-
14
-
-
0035476264
-
Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: A cancer and leukemia group B study
-
Whitman SP, Archer KJ, Feng L, Baldus C, Becknell B, Carlson BD et al. Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B study. Cancer Res 2001;61:7233-7239. (Pubitemid 32946520)
-
(2001)
Cancer Research
, vol.61
, Issue.19
, pp. 7233-7239
-
-
Whitman, S.P.1
Archer, K.J.2
Feng, L.3
Baldus, C.4
Becknell, B.5
Carlson, B.D.6
Carroll, A.J.7
Mrozek, K.8
Vardiman, J.W.9
George, S.L.10
Kolitz, J.E.11
Larson, R.A.12
Bloomfield, C.D.13
Caligiuri, M.A.14
-
15
-
-
0037097716
-
Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: Association with FAB subtypes and identification of subgroups with poor prognosis
-
DOI 10.1182/blood.V99.12.4326
-
Thiede C, Steudel C, Mohr B, Schaich M, Schäkel U, Platzbecker U et al. Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis. Blood 2002;99:4326-4335. (Pubitemid 34627197)
-
(2002)
Blood
, vol.99
, Issue.12
, pp. 4326-4335
-
-
Thiede, C.1
Steudel, C.2
Mohr, B.3
Schaich, M.4
Schakel, U.5
Platzbecker, U.6
Wermke, M.7
Bornhauser, M.8
Ritter, M.9
Neubauer, A.10
Ehninger, G.11
Illmer, T.12
-
16
-
-
41949090673
-
The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia
-
Gale RE, Green C, Allen C, Mead AJ, Burnett AK, Hills RK et al. The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia. Blood 2008;111:2776-2784.
-
(2008)
Blood
, vol.111
, pp. 2776-2784
-
-
Gale, R.E.1
Green, C.2
Allen, C.3
Mead, A.J.4
Burnett, A.K.5
Hills, R.K.6
-
17
-
-
70349579540
-
Minimal residual disease levels assessed by NPM1 mutation specific RQ-PCR provide important prognostic information in AML
-
Schnittger S, Kern W, Tschulik C, Weiss T, Dicker F, Falini B et al. Minimal residual disease levels assessed by NPM1 mutation specific RQ-PCR provide important prognostic information in AML. Blood 2009;114:2220-2231.
-
(2009)
Blood
, vol.114
, pp. 2220-2231
-
-
Schnittger, S.1
Kern, W.2
Tschulik, C.3
Weiss, T.4
Dicker, F.5
Falini, B.6
-
19
-
-
0022135739
-
Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British cooperative group
-
Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DA, Gralnick HR et al. Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group. Ann Intern Med 1985;103:620-625.
-
(1985)
Ann Intern Med
, vol.103
, pp. 620-625
-
-
Bennett, J.M.1
Catovsky, D.2
Daniel, M.T.3
Flandrin, G.4
Galton, D.A.5
Gralnick, H.R.6
-
20
-
-
85009854501
-
Comparison of chromosome banding analysis, interphase- and hypermetaphase-FISH, qualitative and quantitative PCR for diagnosis and for follow-up in chronic myeloid leukemia: A study on 350 cases
-
DOI 10.1038/sj/leu/2402329
-
Schoch C, Schnittger S, Bursch S, Gerstner D, Hochhaus A, Berger U et al. Comparison of chromosome banding analysis, interphase-and hypermetaphase-FISH, qualitative and quantitative PCR for diagnosis and for follow-up in chronic myeloid leukemia: a study on 350 cases. Leukemia 2002;16:53-59. (Pubitemid 34105599)
-
(2002)
Leukemia
, vol.16
, Issue.1
, pp. 53-59
-
-
Schoch, C.1
Schnittger, S.2
Bursch, S.3
Gerstner, D.4
Hochhaus, A.5
Berger, U.6
Hehlmann, R.7
Hiddemann, W.8
Haferlach, T.9
-
21
-
-
5444223232
-
Determination of relapse risk based on assessment of minimal residual disease during complete remission by multiparameter flow cytometry in unselected patients with acute myeloid leukemia
-
DOI 10.1182/blood-2004-03-1036
-
Kern W, Voskova D, Schoch C, Hiddemann W, Schnittger S, Haferlach T. Determination of relapse risk based on assessment of minimal residual disease during complete remission by multiparameter flow cytometry in unselected patients with acute myeloid leukemia. Blood 2004;104:3078-3085. (Pubitemid 39517010)
-
(2004)
Blood
, vol.104
, Issue.10
, pp. 3078-3085
-
-
Kern, W.1
Voskova, D.2
Schoch, C.3
Hiddemann, W.4
Schnittger, S.5
Haferlach, T.6
-
22
-
-
1542753559
-
Revised Recommendations of the International Working Group for diagnosis, standardization of response criteria, treatment outcomes, and reporting standards for therapeutic trials in acute myeloid leukemia
-
DOI 10.1200/JCO.2003.04.036
-
Cheson BD, Bennett JM, Kopecky KJ, Büchner T, Willman CL, Estey EH et al. Revised recommendations of the International Working Group for diagnosis, standardization of response criteria, treatment outcomes, and reporting standards for therapeutic trials in acute myeloid leukemia. J Clin Oncol 2003;21:4642-4649. (Pubitemid 46594039)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.24
, pp. 4642-4649
-
-
Cheson, B.D.1
Bennett, J.M.2
Kopecky, K.J.3
Buchner, T.4
Willman, C.L.5
Estey, E.H.6
Schiffer, C.A.7
Doehner, H.8
Tallman, M.S.9
Lister, T.A.10
LoCocco, F.11
Willemze, R.12
Biondi, A.13
Hiddemann, W.14
Larson, R.A.15
Lowenberg, B.16
Sanz, M.A.17
Head, D.R.18
Ohno, R.19
Bloomfield, C.D.20
more..
-
23
-
-
33646557337
-
Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML)
-
DOI 10.1182/blood-2005-08-3167
-
Thiede C, Koch S, Creutzig E, Steudel C, Illmer T, Schaich M et al. Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML). Blood 2006;107:4011-4020. (Pubitemid 43726809)
-
(2006)
Blood
, vol.107
, Issue.10
, pp. 4011-4020
-
-
Thiede, C.1
Koch, S.2
Creutzig, E.3
Steudel, C.4
Illmer, T.5
Schaich, M.6
Ehninger, G.7
-
24
-
-
42949142189
-
Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia
-
DOI 10.1056/NEJMoa074306
-
Schlenk RF, Döhner K, Krauter J, Fröhling S, Corbacioglu A, Bullinger L et al. Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia. N Engl J Med 2008;358:1909-1918. (Pubitemid 351620111)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.18
, pp. 1909-1918
-
-
Schlenk, R.F.1
Dohner, K.2
Krauter, J.3
Frohling, S.4
Corbacioglu, A.5
Bullinger, L.6
Habdank, M.7
Spath, D.8
Morgan, M.9
Benner, A.10
Schlegelberger, B.11
Heil, G.12
Ganser, A.13
Dohner, H.14
-
25
-
-
2642511275
-
FLT3 length mutations as marker for follow-up studies in acute myeloid leukaemia
-
DOI 10.1159/000077561
-
Schnittger S, Schoch C, Kern W, Hiddemann W, Haferlach T. FLT3 length mutations as marker for follow-up studies in acute myeloid leukaemia. Acta Haematol 2004;112:68-78. (Pubitemid 38716251)
-
(2004)
Acta Haematologica
, vol.112
, Issue.1-2
, pp. 68-78
-
-
Schnittger, S.1
Schoch, C.2
Kern, W.3
Hiddemann, W.4
Haferlach, T.5
|