Targeting RNA by small molecules: Comparative structural and thermodynamic aspects of aristololactam-β-D-glucoside and daunomycin binding to tRNA phe

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Das, Abhi ^a   Bhadra, Kakali ^a,b   Kumar, Gopinatha Suresh ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

^b UNIVERSITY OF KALYANI   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ARISTOLOLACTAM GLUCOSIDE; DAUNORUBICIN; PHENYLALANINE TRANSFER RNA; ANTINEOPLASTIC ANTIBIOTIC; ARISTOLOCHIC ACID; ARISTOLOLACTAM-GLUCOSIDE; GLUCOSIDE; RNA;

ARTICLE; BINDING AFFINITY; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG BINDING; DRUG MECHANISM; DRUG STRUCTURE; ENTHALPY; ENTROPY; FLUORESCENCE ANALYSIS; GENE TARGETING; IONIC STRENGTH; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR INTERACTION; QUANTUM CHEMISTRY; RNA BINDING; RNA STABILITY; STATIC ELECTRICITY; THERMOSTABILITY; ALGORITHM; BINDING COMPETITION; BINDING SITE; CALORIMETRY; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; CONFORMATION; DRUG EFFECT; GENETICS; KINETICS; METABOLISM; SPECTROFLUOROMETRY; THERMODYNAMICS;

ALGORITHMS; ANTIBIOTICS, ANTINEOPLASTIC; ARISTOLOCHIC ACIDS; BINDING SITES; BINDING, COMPETITIVE; CALORIMETRY; CIRCULAR DICHROISM; DAUNORUBICIN; ENTROPY; GLUCOSIDES; KINETICS; MOLECULAR STRUCTURE; NUCLEIC ACID CONFORMATION; RNA; RNA, TRANSFER, PHE; SPECTROMETRY, FLUORESCENCE; THERMODYNAMICS;

EID: 80051675861     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023186     Document Type: Article

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