RNA and the small molecule world

Angewandte Chemie - International Edition

Volumn 38, Issue 11, 1999, Pages 1579-1582

  Tor, Yitzhak ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aminoglycosides; Antibiotics; Gene technology; RNA; Translation

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; DNA; KANAMYCIN A; PROTEIN; RNA; TOBRAMYCIN;

ANTIMICROBIAL THERAPY; DRUG TARGETING; GENE EXPRESSION REGULATION; GENE TECHNOLOGY; MOLECULAR RECOGNITION; PROTEIN SYNTHESIS; REVIEW; RNA STRUCTURE; RNA TRANSCRIPTION; RNA TRANSLATION;

EID: 0033152070     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3773(19990601)38:11<1579::AID-ANIE1579>3.0.CO;2-H     Document Type: Review

References (82)

1. For a wonderful monograph discussing the evolution of molecular biology, its major discoveries and makers, see H. F. Judson, The Eighth Day of Creation, Simon & Schuster, New York, 1980.
2. A. Rich in Horizons in Biochemistry (Eds.: M. Kasha, B. Pullman), Academic Press, New York, 1962, pp. 103-126.
3. Recent reviews: a) G. Varani, K. Nagai, Annu. Rev. Biophys. Biomol. Struct. 1998, 27, 407-445;
4. b) N. K. Gray, M. Wickens, Annu. Rev. Cell. Dev. Biol. 1998, 14, 399-458;
5. c) H. Siomi, G. Dreyfuss, Curr. Opin. Gen. Dev. 1997, 7, 345-353.
6. a) T. Hermann, E. Westhof, Curr. Opin. Biotechnol. 1998, 9, 66-73;
7. b) N. D. Pearson, C. D. Prescott, Chem. Biol. 1997, 4, 409-414.
8. K. Michael, Y. Tor, Chem. Eur. J. 1998, 4, 2091-2098.
9. It is impossible to capture all the exciting developments and their contributors within such a short account. The interested reader is referred to ref. [1] and to an excellent textbook: J. D. Watson, N. H. Hopkins, J. W. Roberts, J. A. Steitz, A. M. Weiner, Molecular Biology of the Gene, 4th ed., Benjamin/Cummings, Menlo Park, 1987.
10. T. Caspersson, J. Schultz, Nature 1939, 143, 602-603. In those days the term pentose nucleic acids was used in reference to RNA. See T. Caspersson, Chromosoma 1940, 1, 605-619.
11. T. Caspersson, J. Schultz, Nature 1939, 143, 602-603. In those days the term pentose nucleic acids was used in reference to RNA. See T. Caspersson, Chromosoma 1940, 1, 605-619.
12. a) A. Claude, Science 1940, 91, 77-78;
13. b) A. Claude, Cold Spring Harbor Symp. Quant. Biol. 1941, 9, 263-271.
14. J. Brachet, Symp. Soc. Exp. Biol. 1947, 1, 207-224.
15. G. E. Palade, J. Biophys. Biochem. Cytol. 1955, 1, 59-68.
16. J. W. Littlefield, E. B. Keller, J. Gross, P. C. Zamecnik, J. Biol. Chem. 1955, 217, 111-123.
17. For a historical account, see A. Tissières in Ribosomes (Eds.: M. Nomura, A. Tissières), Cold Spring Harbor Laboratory Press, New York, 1974, pp. 3-12.
18. A. Boivin, R. Vendrely, Experientia 1947, 3, 32-34.
19. J. D. Watson, F. H. C. Crick, Nature 1953, 171, 737-738.
20. F. Jacob, J. Monod, J. Mol. Biol. 1961, 3, 318-356.
21. a) S. Brenner, F. Jacob, M. Meselson, Nature 1961, 190, 576-581;
22. b) F. Gros, H. Hiatt, W. Gilbert, C. G. Kurland, R. W. Risebrough, J. D. Watson, Nature 1961, 190, 581-585.
23. M. B. Hoagland, M. L. Stephenson, J. F. Scott, L. I. Hecht, P. C. Zamecnik, J. Biol. Chem. 1958, 231,241-257. See also M. Hoagland. Trends Biochem. Sci. 1996, 21, 77-80.
24. M. B. Hoagland, M. L. Stephenson, J. F. Scott, L. I. Hecht, P. C. Zamecnik, J. Biol. Chem. 1958, 231,241-257. See also M. Hoagland. Trends Biochem. Sci. 1996, 21, 77-80.
25. F. Chapeville, F. Lipman, G. von Ehrenstein, B. Weisblum, W. J. Ray, S. Benzer, Proc. Natl. Acad. Sci. USA 1962, 48, 1086-1092.
26. F. H. C. Crick, an unpublished note to the RNA Tie Club. 1955. See also ref. [1], and F. H. C. Crick, What Mad Pursuit, Basic Books, New York, 1988.
27. F. H. C. Crick, an unpublished note to the RNA Tie Club. 1955. See also ref. [1], and F. H. C. Crick, What Mad Pursuit, Basic Books, New York, 1988.
28. A key experiment: M. W. Nirenberg, J. H. Matthaei, Proc. Natl. Acad. Sci. USA 1961, 47, 1588-1602. See also "The Genetic Code": Cold Spring Harbor Symp. Quant. Biol. 1966, 31.
29. A key experiment: M. W. Nirenberg, J. H. Matthaei, Proc. Natl. Acad. Sci. USA 1961, 47, 1588-1602. See also "The Genetic Code": Cold Spring Harbor Symp. Quant. Biol. 1966, 31.
30. R. Green, H. F. Noller, Annu. Rev. Biochem. 1997, 66, 679-716.
31. H. F. Noller, V. Hoffarth, L. Zimniak, Science 1992, 256, 1416-1419.
32. I. Nitta, Y. Kamada, H. Noda, T. Ueda, K. Watanabe, Science 1998, 281, 666-669.
33. T. R. Cech, Science 1987, 236, 1532-1539.
34. P. Schimmel, R. Alexander, Science 1998, 281, 658-659.
35. a) M. Chastain, I. Tinoco, Jr., Prog. Nucl. Acid Res. Mol. Biol. 1991, 41, 131-177;
36. b) J. Doudna, R. T. Batey, R. P. Rambo, Angew. Chem. 1999, in press.
37. C. S. Chow, F. M. Bogdan, Chem. Rev. 1997, 97, 1489-1513.
38. a) B. A. Newton, P. E. Reynolds. Biochemical Studies of Antimicrobial Drugs, University Press, Cambridge, 1966;
39. (b) D. Vázquez, Inhibitors of Protein Biosynthesis, Springer, Berlin, 1979;
40. E. F. Gale, E. Cundliffe, P. E. Reynolds, M. H. Richmond, M. J. Waring, The Molecular Basis of Antibiotics Action, 2nd ed., Wiley, Chichester, 1981.
41. D. Moazed, H. F. Noller, Nature 1987, 327, 389-394.
42. a) U. von Ahsen, J. Davies, R. Schroeder, Nature 1991, 353, 368-370:
43. b) U. von Ahsen, J. Davies, R. Schroeder, J. Mol. Biol. 1992, 226, 935-941;
44. c) J. Davies, U. von Ahsen, R. Schroeder in The RNA World (Eds.: R. F. Gesteland, J. F. Atkins), Cold Spring Harbor Laboratory Press, New York, 1993, pp. 185-204.
45. T. K. Stage, K. J. Hertel, O. C. Uhlenbeck, RNA 1995, 1, 95-101.
46. a) J. Rogers, A. H. Chang, U. von Ahsen, R. Schroeder, J. Davies, J. Mol. Biol. 1996, 259, 916-925;
47. b) J.-S. Chia, H.-L. Wu, H.-W. Wang, D.-S. Chen, P.-J. Chen, J. Biomed. Sci. 1997, 4, 208-216.
48. P. Purohit, S. Stern, Nature 1994, 370, 659-662.
49. H. Miyaguchi, H. Narita, K. Sakamoto, S. Yokoyama, Nucleic Acids Res. 1996, 24, 3700-3706.
50. a) M. I. Recht, D. Fourmy, S. C. Blanchard, K. D. Dahlquist, J. D. Puglisi, J. Mol. Biol. 1996, 262, 421-436;
51. b) D. Fourmy, M. I. Recht, S. C. Blanchard, J. D. Puglisi, Science 1996, 274, 1367-1371;
52. c) D. Fourmy, S. Yoshozawa, J. D. Puglisi, J. Mol. Biol. 1998, 277, 333-345.
53. S. R. Kirk, Y. Tor, Bioorg. Med. Chem., in press.
54. a) Y. Wang, R. R. Rando, Chem. Biol. 1995, 2, 281-290;
55. b) S. M. Lato, A. R. Boles, A. D. Ellington, Chem. Biol. 1995, 2, 291-303;
56. c) M. G. Wallis, U. von Ahsen, R. Schroeder, M. Famulok, Chem. Biol. 1995, 2, 543-552;
57. d) M. Famulok, A. Hüttenhofer, Biochemistry 1996, 35, 4265-4270;
58. e) S. T. Wallace, R. Schroeder, RNA 1998, 4, 112-123.
59. a) L. Jiang, A. K. Suri, R. Fiala, D. J. Patel, Chem. Biol. 1997, 4, 35-50.
60. b) L. C. Jiang, D. J. Patel, Nat. Struct. Biol. 1998, 5, 769-774.
61. M. L. Zapp, S. Stern, M. R. Green, Cell 1993, 74, 969-978.
62. H.-Y. Mei, A. A. Galan, N. S. Halim, D. P. Mack, D. W. Moreland, K. B. Sanders, H. N. Truong, A. W. Czarnik, Bioorg. Med. Chem. Lett. 1995, 5, 2755-2760.
63. L. Ratmeyer, M. L. Zapp, M. R. Green, R. Vinayak, A. Kumar, D. W. Boykin, W. D. Wilson, Biochemistry 1996, 35, 13 689-13 696.
64. F. Hamy, V. Brondani, A. Flörsheimer, W. Stark, M. J. J. Blommers, T. Klimkait, Biochemistry 1998, 37, 5086-5095.
65. H.-Y. Mei, M. Cui, A. Heldsinger, S. M. Lemrow, J. A. Loo, K. A. Sannes-Lowery, L. Sharmeen, A. W. Czarnik, Biochemistry 1998, 37, 14 204-14 212.
66. a) M. Hendrix, E. S. Priestley, G. F. Joyce, C.-H. Wong, J. Am. Chem. Soc. 1997, 119, 3641-3648;
67. b) P. B. Alper, M. Hendrix, P. Sears, C.-H. Wong, J. Am. Chem. Soc. 1998, 120, 1965-1978;
68. c) Y. Wang, K. Hamasaki, R. R. Rando, Biochemistry 1997, 36, 768-779.
69. H. Wang, Y. Tor, Angew. Chem. 1998, 110, 117-120; Angew. Chem. Int. Ed. 1998, 37, 109-111.
70. H. Wang, Y. Tor, Angew. Chem. 1998, 110, 117-120; Angew. Chem. Int. Ed. 1998, 37, 109-111.
71. T. Hermann, E. Westhof, J. Mol. Biol. 1998, 276, 903-912.
72. Y. Tor, T. Hermann, E. Westhof, Chem. Biol. 1998, 5, R277-R283.
73. G. Werstuck, M. R. Green, Science 1998, 282, 296-298.
74. a) H. Umezawa, Adv. Carbohydr. Chem. Biochem. 1974, 30, 183-225;
75. b) J. Davies, D. I. Smith, Annu. Rev. Microbiol. 1978, 32, 469-518.
76. a) H. Umezawa, Adv. Carbohydr. Chem. Biochem. 1974, 30, 183-225;
77. b) J. Davies, D. I. Smith, Annu. Rev. Microbiol. 1978, 32, 469-518.
78. A cap-binding RNA aptamer has been shown to specifically inhibit the translation of a capped but not uncapped mRNA molecules in cell free lysates. See A. A. Haller, P. Sarnow, Proc. Natl. Acad. Sci. USA 1997, 94, 8521-8526.
79. a) H.-Y. Mei, M. Cui, S. T. Sutton, H. N. Truong, F-Z. Chung, A. W. Czarnik, Nucleic Acids Res. 1996, 24, 5051-5053;
80. b) R. H. Griffey, M. J. Greig, H. An, H. Sasmor, S. Manalili, J. Am. Chem. Soc. 1999, 121, 474-475.
81. B. W. J. Mahy, Antiviral Res. 1997, 36, 75-80.
82. R. M. Krause, Emerging Infections, Academic Press, San Diego, 1998.