Hyaluronan-based heparin-incorporated hydrogels for generation of axially vascularized bioartificial bone tissues: In vitro and in vivo evaluation in a PLDLLA-TCP-PCL-composite system

Journal of Materials Science: Materials in Medicine

Volumn 22, Issue 5, 2011, Pages 1279-1291

  Rath, Subha N ^a,b   Pryymachuk, Galyna ^a   Bleiziffer, Oliver A ^a   Lam, Christopher X F ^b   Arkudas, Andreas ^a   Ho, Saey T B ^c   Beier, Justus P ^a   Horch, Raymund E ^a   Hutmacher, Dietmar W ^d   Kneser, Ulrich ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOARTIFICIAL; BONE FORMATION; BONE GRAFT; BONE TISSUE; HYALURONAN; IN-VITRO; IN-VIVO; OPTIMAL ENVIRONMENT; OSTEOBLAST GROWTH; OSTEOGENIC CELLS; PRIMARY OSTEOBLASTS; RAPID PROTOTYPING TECHNOLOGY; REAL TIME RT-PCR; RECONSTRUCTIVE SURGERY; SUSTAINED RELEASE; TISSUE-ENGINEERED GRAFTS; VASCULARIZATION; VASCULARIZED TISSUES;

ARTIFICIAL ORGANS; BIOMECHANICS; GENE EXPRESSION; HYDROGELS; OPTIMIZATION; OSTEOBLASTS; POLYSACCHARIDES; RAPID PROTOTYPING; SCAFFOLDS (BIOLOGY); TISSUE;

BONE;

ALKALINE PHOSPHATASE; BIGLYCAN; BIOMATERIAL; BONE MORPHOGENETIC PROTEIN 2; BONE SIALOPROTEIN; COLLAGEN TYPE 1; FIBROBLAST GROWTH FACTOR 2; HEPARIN; HYALURONIC ACID; OSTEOCALCIN; OSTEONECTIN; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; SYNDECAN; TISSUE SCAFFOLD; TRANSCRIPTION FACTOR RUNX2; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTIFICIAL BONE; BIODEGRADATION; BIOMECHANICS; BLOOD VESSEL; BONE GRAFT; BONE TISSUE; CELL GROWTH; CELL PROLIFERATION; COMPOSITE MATERIAL; CONTROLLED STUDY; GENE EXPRESSION; HISTOLOGY; HYDROGEL; IN VITRO STUDY; MALE; MICRO-COMPUTED TOMOGRAPHY; MORPHOMETRICS; NONHUMAN; OSSIFICATION; OSTEOBLAST; POROSITY; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN SECRETION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE ENGINEERING; VASCULARIZATION;

ANIMALS; BONE DEMINERALIZATION TECHNIQUE; BONE MORPHOGENETIC PROTEIN 2; BONE SUBSTITUTES; CALCIUM PHOSPHATES; HEPARIN; HUMANS; HYALURONIC ACID; HYDROGELS; MALE; NEOVASCULARIZATION, PHYSIOLOGIC; OSTEOBLASTS; POLYESTERS; RATS; RATS, INBRED LEW; TISSUE SCAFFOLDS;

RATTUS;

EID: 80051670010     PISSN: 09574530     EISSN: 15734838     Source Type: Journal    
DOI: 10.1007/s10856-011-4300-0     Document Type: Article

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