Design and validation of a novel bioreactor to subject aortic valve leaflets to side-specific shear stress

Annals of Biomedical Engineering

Volumn 39, Issue 8, 2011, Pages 2174-2185

  Sun, Ling ^a   Rajamannan, Nalini M ^b   Sucosky, Philippe ^a  

^a University of Notre Dame   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Flow; Hemodynamics; Inflammation; Mechanobiology; Remodeling; Signal transduction

Indexed keywords

AORTIC VALVE LEAFLETS; AORTIC VALVES; CONE-AND-PLATE GEOMETRY; FLOW; FLOW ENVIRONMENT; INFLAMMATION; MECHANO-BIOLOGY; NEW DEVICES; NOVEL DEVICES; REMODELING; STRESS MECHANISMS; TIME-DEPENDENT; TISSUE SAMPLES;

BIOREACTORS; BLOOD VESSELS; CELL DEATH; HEMODYNAMICS; HYDRODYNAMICS; PATHOLOGY; SHEAR STRESS; SIGNAL TRANSDUCTION; TISSUE;

SHEAR FLOW;

ANIMAL; AORTA VALVE; APOPTOSIS; ARTICLE; BIOLOGICAL MODEL; BIOREACTOR; CALCINOSIS; ENDOTHELIUM; HUMAN; METABOLISM; ORGAN CULTURE TECHNIQUE; PATHOLOGY; PHYSIOLOGICAL STRESS; SWINE; VALVULAR HEART DISEASE;

ANIMALS; AORTIC VALVE; APOPTOSIS; BIOREACTORS; CALCINOSIS; ENDOTHELIUM; HEART VALVE DISEASES; HUMANS; MODELS, CARDIOVASCULAR; ORGAN CULTURE TECHNIQUES; STRESS, PHYSIOLOGICAL; SWINE;

EID: 80051552953     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-011-0305-6     Document Type: Article

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