Design of an ex vivo culture system to investigate the effects of shear stress on cardiovascular tissue

Journal of Biomechanical Engineering

Volumn 130, Issue 3, 2008, Pages

  Sucosky, Philippe ^a   Padala, Muralidhar ^a   Elhammali, Adnan ^a   Balachandran, Kartik ^a   Jo, Hanjoong ^b   Yoganathan, Ajit P ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b Emory University   (United States)

Author keywords

Bioreactor; Cone and plate; Heart valve; Mechanotransduction; Shear stress; Tissue engineering; Viscometer

Indexed keywords

BIOMECHANICS; CELL CULTURE; CHEMICAL REACTORS; COMPUTATIONAL FLUID DYNAMICS; DOPPLER EFFECT; DYNAMIC MODELS; FISH; FLUID DYNAMICS; FLUID MECHANICS; HEMODYNAMICS; MECHANICAL PROPERTIES; METALLURGY; MOLECULAR BEAM EPITAXY; PHOTOACOUSTIC EFFECT; PLATES (STRUCTURAL COMPONENTS); PULSED LASER DEPOSITION; SECONDARY FLOW; SHEAR STRESS; SHEARING MACHINES; STRENGTH OF MATERIALS; STRESSES; THEOREM PROVING; TISSUE CULTURE; VALVES (MECHANICAL);

(ABIOTIC AND BIOTIC) STRESS; BIOLOGICAL RESPONSES; BIOLOGICAL TISSUES; BIOMECHANICAL PROPERTIES; BLOOD FLOWS; CARDIOVASCULAR TISSUES; CONE ANGLES; DIFFERENT TYPES; EX-VIVO; FLOW EFFECTS; FLOW PERTURBATIONS; HEART VALVES; IN ORDER; IN-VIVO; INNOVATIVE DESIGNS; LASER-DOPPLER VELOCIMETRY (LDV); MECHANICAL ENVIRONMENT; MECHANICAL FORCES; NOVEL APPARATUS; OPERATING CONDITIONS; PLATE SYSTEMS; RELATIVE MOTIONS; STERILE CONDITIONS; STRESS CONDITIONS; STRESS PRO FILES; STRESS RATES; TIME-VARYING SHEAR STRESS; TISSUE SAMPLES; TISSUE SPECIMENS; TISSUE THICKNESS; WAVE FORMS;

TISSUE;

AORTA VALVE; ARTICLE; BIOMECHANICS; CARDIOVASCULAR SYSTEM; EX VIVO STUDY; FORCE; HEART VALVE; LASER DOPPLER FLOWMETRY; REPRODUCIBILITY; SHEAR STRESS; TISSUE CULTURE; TISSUE ENGINEERING; VALIDATION PROCESS; VISCOMETER; WAVEFORM; AUDIOVISUAL EQUIPMENT; BIOLOGICAL MODEL; BLOOD RHEOLOGY; DIFFUSION CHAMBER; EQUIPMENT; EQUIPMENT DESIGN; HUMAN; INSTRUMENTATION; MECHANICAL STRESS; METHODOLOGY; PHYSIOLOGY; SHEAR STRENGTH; TISSUE CULTURE TECHNIQUE;

DIFFUSION CHAMBERS, CULTURE; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; HEART VALVES; HEMORHEOLOGY; HUMANS; LASER-DOPPLER FLOWMETRY; MODELS, CARDIOVASCULAR; MODELS, STRUCTURAL; SHEAR STRENGTH; STRESS, MECHANICAL; TISSUE CULTURE TECHNIQUES;

EID: 46749091675     PISSN: 01480731     EISSN: None     Source Type: Journal    
DOI: 10.1115/1.2907753     Document Type: Article

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