A bifunctional organometallic ruthenium drug with multiple modes of inducing apoptosis

Journal of Biological Inorganic Chemistry

Volumn 16, Issue 5, 2011, Pages 715-724

  Chatterjee, Soumya ^a,c   Biondi, Ilaria ^b   Dyson, Paul J ^b   Bhattacharyya, Arindam ^c  

^a UNIVERSITY OF KALYANI   (India)

^b EPFL   (Switzerland)

^c UNIVERSITY OF CALCUTTA   (India)

Author keywords

Bioorganometallic chemistry; Chemotherapeutics; Mitochondria; Reactive oxygen species; Ruthenium

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE; CISPLATIN; ENDONUCLEASE G; ETHARAPTA; HEAT SHOCK PROTEIN 70; RUTHENIUM DERIVATIVE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CANCER RESISTANCE; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG MECHANISM; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CISPLATIN; DRUG RESISTANCE, NEOPLASM; FEMALE; GLUTATHIONE TRANSFERASE; HUMANS; MITOCHONDRIA; ORGANOMETALLIC COMPOUNDS; REACTIVE OXYGEN SPECIES; RUTHENIUM COMPOUNDS;

EID: 80051552329     PISSN: 09498257     EISSN: 14321327     Source Type: Journal    
DOI: 10.1007/s00775-011-0772-0     Document Type: Article

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