Pharmacological induction of Hsp70 protects apoptosis-prone cells from doxorubicin: Comparison with caspase-inhibitor- and cycle-arrest-mediated cytoprotection

Cell Death and Differentiation

Volumn 13, Issue 9, 2006, Pages 1434-1441

  Demidenko, Z N ^a   Vivo, C ^b   Halicka, H D ^a   Li, C J ^c   Bhalla, K ^d   Broude, E V ^b   Blagosklonny, M V ^a,b  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b ORDWAY RESEARCH INSTITUTE   (United States)

^c ARQULE INC   (United States)

^d H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

17 ALLYLAMINO 17 DEMETHOXYGELDANAMYCIN; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE INHIBITOR; DACTINOMYCIN; DOXORUBICIN; FLAVOPIRIDOL; GELDANAMYCIN; HEAT SHOCK PROTEIN 70; PACLITAXEL; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL PROTECTION; CELL TYPE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; NICK END LABELING; PHARMACOLOGICAL STIMULATION; PRIORITY JOURNAL;

AMINO ACID CHLOROMETHYL KETONES; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; BENZOQUINONES; CASPASE 9; CELL CYCLE; CELL LINE, TUMOR; CYTOPROTECTION; DACTINOMYCIN; DOXORUBICIN; ENZYME ACTIVATION; FLAVONOIDS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; PACLITAXEL; PIPERIDINES; PROTEIN BIOSYNTHESIS; RNA, SMALL INTERFERING; TRANS-ACTIVATION (GENETICS); TRANSCRIPTIONAL ACTIVATION;

EID: 33747041690     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401812     Document Type: Article

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