메뉴 건너뛰기




Volumn 122, Issue 3, 2011, Pages 495-500

Phase II trial of cetuximab in the treatment of persistent or recurrent squamous or non-squamous cell carcinoma of the cervix: A Gynecologic Oncology Group study

Author keywords

Cervical neoplasms; Cetuximab; EGFR; Immunotherapy

Indexed keywords

CETUXIMAB;

EID: 80051551247     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2011.05.040     Document Type: Article
Times cited : (107)

References (58)
  • 2
    • 0030875607 scopus 로고    scopus 로고
    • Randomised study of radical surgery versus radiotherapy for stage Ib-IIa cervical cancer
    • DOI 10.1016/S0140-6736(97)02250-2
    • F. Landoni, A. Maneo, A. Colombo, F. Placa, R. Milani, and P. Perego Randomized study of radical surgery versus radiotherapy for stage Ib-IIa cervical cancer Lancet 350 1997 535 540 (Pubitemid 27348428)
    • (1997) Lancet , vol.350 , Issue.9077 , pp. 535-540
    • Landoni, F.1    Maneo, A.2    Colombo, A.3    Placa, F.4    Milani, R.5    Perego, P.6    Favini, G.7    Ferri, L.8    Mangioni, C.9
  • 3
    • 0037010076 scopus 로고    scopus 로고
    • Overview of epidermal growth factor receptor biology and its role as a therapeutic target in human neoplasia
    • C.L. Arteaga Overview of epidermal growth factor receptor biology and its role as a therapeutic target in human neoplasia Semin Oncol 29 2002 3 9 (Pubitemid 35191041)
    • (2002) Seminars in Oncology , vol.29 , Issue.5 SUPPL. 14 , pp. 3-9
    • Arteaga, C.L.1
  • 4
    • 0034332542 scopus 로고    scopus 로고
    • New therapeutic agents targeting the epidermal growth factor receptor
    • J. Baselga New therapeutic agents targeting the epidermal growth factor receptor J Clin Oncol 18 2000 54S 59S
    • (2000) J Clin Oncol , vol.18
    • Baselga, J.1
  • 5
    • 0033757709 scopus 로고    scopus 로고
    • Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy
    • discussion, 41-42
    • E. Raymond, S. Faivre, and J.P. Armand Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy Drugs 60 2000 15 23 discussion, 41-42
    • (2000) Drugs , vol.60 , pp. 15-23
    • Raymond, E.1    Faivre, S.2    Armand, J.P.3
  • 6
    • 0035884307 scopus 로고    scopus 로고
    • Targeting the epidermal growth factor receptor: A clinical reality
    • J. Baselga Targeting the epidermal growth factor receptor: a clinical reality J Clin Oncol 19 2001 41S 44S (Pubitemid 32880078)
    • (2001) Journal of Clinical Oncology , vol.19 , Issue.18 SUPPL.
    • Baselga, J.1
  • 7
    • 0037010079 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-targeted therapy in colorectal cancer
    • P.J. O'Dwyer, and A.B. Benson III Epidermal growth factor receptor-targeted therapy in colorectal cancer Semin Oncol 29 Suppl. 14 2002 10 11
    • (2002) Semin Oncol , vol.29 , Issue.SUPPL. 14 , pp. 10-11
    • O'Dwyer, P.J.1    Benson Iii, A.B.2
  • 8
    • 0034722889 scopus 로고    scopus 로고
    • The EGF receptor family as targets for cancer therapy
    • DOI 10.1038/sj.onc.1204082
    • J. Mendelsohn, and J. Baselga The EGF receptor family as targets for cancer therapy Oncogene 19 2000 6550 6565 (Pubitemid 32197693)
    • (2000) Oncogene , vol.19 , Issue.56 , pp. 6550-6565
    • Mendelsohn, J.1    Baselga, J.2
  • 9
    • 0037145061 scopus 로고    scopus 로고
    • Ligand-induced, receptor-mediated dimerization and activation of EGF receptor
    • DOI 10.1016/S0092-8674(02)00966-2
    • J. Schlessinger Ligand-induced, receptor-mediated dimerization and activation of EGF receptor Cell 110 2002 669 672 (Pubitemid 35283957)
    • (2002) Cell , vol.110 , Issue.6 , pp. 669-672
    • Schlessinger, J.1
  • 10
    • 0033779765 scopus 로고    scopus 로고
    • Single-molecule imaging of EGFR signaling on the surface of living cells
    • Y. Sako, S. Minoghchi, and T. Yanagida Single-molecule imaging of EGFR signaling on the surface of living cells Nat Cell Biol 2 2000 168 172
    • (2000) Nat Cell Biol , vol.2 , pp. 168-172
    • Sako, Y.1    Minoghchi, S.2    Yanagida, T.3
  • 11
    • 0034644539 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • J. Schlessinger Cell signaling by receptor tyrosine kinases Cell 103 2000 211 225
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 12
    • 0033546315 scopus 로고    scopus 로고
    • ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases
    • M.A. Olayioye, I. Beuvink, K. Horsch, J.M. Daly, and N.E. Hynes ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases J Biol Chem 274 1999 17209 17218
    • (1999) J Biol Chem , vol.274 , pp. 17209-17218
    • Olayioye, M.A.1    Beuvink, I.2    Horsch, K.3    Daly, J.M.4    Hynes, N.E.5
  • 13
    • 0033604516 scopus 로고    scopus 로고
    • The role of the epidermal growth factor receptor family in mammary tumorigenesis and metastasis
    • H. Kim, and W.J. Muller The role of the epidermal growth factor receptor family in mammary tumorigenesis and metastasis Exp Cell Res 253 1999 78 87
    • (1999) Exp Cell Res , vol.253 , pp. 78-87
    • Kim, H.1    Muller, W.J.2
  • 15
    • 0031054990 scopus 로고    scopus 로고
    • Epidermal growth factor receptor family and chemosensitization
    • J. Mendelsohn, and Z. Fan Epidermal growth factor receptor family and chemosensitization J Natl Cancer Inst 89 1997 341 343 (Pubitemid 27102599)
    • (1997) Journal of the National Cancer Institute , vol.89 , Issue.5 , pp. 341-343
    • Mendelsohn, J.1    Fan, Z.2
  • 16
    • 0035746349 scopus 로고    scopus 로고
    • Biological predictors of response to radiotherapy in head and neck cancer: Recent advances and emerging perspectives
    • R. Corvo, P. Antognoni, and G. Sanguineti Biological predictors of response to radiotherapy in head and neck cancer: recent advances and emerging perspectives Tumori 87 2001 355 363
    • (2001) Tumori , vol.87 , pp. 355-363
    • Corvo, R.1    Antognoni, P.2    Sanguineti, G.3
  • 18
    • 12144290754 scopus 로고    scopus 로고
    • Synchronous Coexpression of Epidermal Growth Factor Receptor and Cyclooxygenase-2 in Carcinomas of the Uterine Cervix: A Potential Predictor of Poor Survival
    • DOI 10.1158/1078-0432.CCR-0497-03
    • G.E. Kim, Y.B. Kim, N.H. Cho, H.C. Chung, H.R. Pyo, and J.D. Lee Synchronous co-expression of epidermal growth factor receptor and cyclooxygenase-2 in carcinomas of the uterine cervix: a potential predictor of poor survival Clin Cancer Res 10 2004 1366 1374 (Pubitemid 38365230)
    • (2004) Clinical Cancer Research , vol.10 , Issue.4 , pp. 1366-1374
    • Kim, G.E.1    Kim, Y.B.2    Cho, N.H.3    Chung, H.-C.4    Pyo, H.R.5    Lee, J.D.6    Park, T.K.7    Koom, W.S.8    Chun, M.9    Suh, C.O.10
  • 19
    • 19244366949 scopus 로고    scopus 로고
    • Phase i studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin
    • J. Baselga, D. Pfister, M.R. Cooper, R. Cohen, B. Burtness, and M. Bos Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin J Clin Oncol 18 2000 904-4
    • (2000) J Clin Oncol , vol.18 , pp. 904-4
    • Baselga, J.1    Pfister, D.2    Cooper, M.R.3    Cohen, R.4    Burtness, B.5    Bos, M.6
  • 21
    • 0010233988 scopus 로고
    • Growth stimulation of A431 cells by epidermal growth factor: Identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody
    • T. Kawamoto, J.D. Sato, A. Le, J. Polikoff, G.H. Sato, and J. Mendelsohn Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody Proc Natl Acad Sci U S A 80 1983 1337 1341 (Pubitemid 13082800)
    • (1983) Proceedings of the National Academy of Sciences of the United States of America , vol.80 , Issue.5 , pp. 1337-1341
    • Kawamoto, T.1    Sato, J.D.2    Le, A.3
  • 22
    • 0020933452 scopus 로고
    • Biological effects in vitro of monoclonal antibodies to human epidermal growth factor receptors
    • J.D. Sato, T. Kawamoto, A.D. Le, J. Mendelsohn, J. Polikoff, and G.H. Sato Biological effects in vitro of monoclonal antibodies to human epidermal growth factor receptors Mol Biol Med 1 1983 511 529
    • (1983) Mol Biol Med , vol.1 , pp. 511-529
    • Sato, J.D.1    Kawamoto, T.2    Le, A.D.3    Mendelsohn, J.4    Polikoff, J.5    Sato, G.H.6
  • 23
    • 0028116305 scopus 로고
    • Antibody-induced epidermal growth factor receptor dimerization mediates inhibition of autocrine proliferation of A431 squamous carcinoma cells
    • Z. Fan, Y. Lu, X. Wu, and J. Mendelsohn Antibody-induced epidermal growth factor receptor dimerization mediates inhibition of autocrine proliferation of A431 squamous carcinoma cells J Biol Chem 269 1994 27595 27602 (Pubitemid 24346592)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.44 , pp. 27595-27602
    • Fan, Z.1    Lu, Y.2    Wu, X.3    Mendelsohn, J.4
  • 24
    • 0029670014 scopus 로고    scopus 로고
    • Involvement of p27KIP1 in G1 arrest mediated by an anti-epidermal growth factor receptor monoclonal antibody
    • X. Wu, M. Rubin, Z. Fan, T. DeBlasio, T. Soos, and A. Koff Involvement of p27KIP1 in G1 arrest mediated by an anti-epidermal growth factor receptor monoclonal antibody Oncogene 12 1996 1397 1403
    • (1996) Oncogene , vol.12 , pp. 1397-1403
    • Wu, X.1    Rubin, M.2    Fan, Z.3    Deblasio, T.4    Soos, T.5    Koff, A.6
  • 25
    • 0032572699 scopus 로고    scopus 로고
    • Nuclear targeting of Bax during apoptosis in human colorectal cancer cells
    • M. Mandal, L. Adam, J. Mendelsohn, and R. Kumar Nuclear targeting of Bax during apoptosis in human colorectal cancer cells Oncogene 17 1998 999 1007 (Pubitemid 28425410)
    • (1998) Oncogene , vol.17 , Issue.8 , pp. 999-1007
    • Mandal, M.1    Adam, L.2    Mendelsohn, J.3    Kumar, R.4
  • 26
    • 0001223491 scopus 로고    scopus 로고
    • Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: Angiogenic implications for signal transduction therapy of solid tumors
    • A.M. Petit, J. Rak, M.C. Hung, P. Rockwell, N. Goldstein, and B. Fendly Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors Am J Pathol 151 1997 1523 1530 (Pubitemid 27527914)
    • (1997) American Journal of Pathology , vol.151 , Issue.6 , pp. 1523-1530
    • Viloria Petit, A.M.1    Rak, J.2    Hung, M.-C.3    Rockwell, P.4    Goldstein, N.5    Fendly, B.6    Kerbel, R.S.7
  • 27
    • 0003018496 scopus 로고    scopus 로고
    • Blockade of EGF-R signalling with anti-EGFR monoclonal antibody (Mb) C225 inhibits matrix metalloproteinase-9 (MMP-9) expression and invasion of human transitional cell carcinoma (TCC) in vitro and in vivo
    • (Abs)
    • T. Matsumoto, P. Perrotte, and M. Bar-Eli Blockade of EGF-R signalling with anti-EGFR monoclonal antibody (Mb) C225 inhibits matrix metalloproteinase-9 (MMP-9) expression and invasion of human transitional cell carcinoma (TCC) in vitro and in vivo Proc Am Assoc Cancer Res 39 83 1998 (Abs)
    • (1998) Proc Am Assoc Cancer Res , vol.39 , Issue.83
    • Matsumoto, T.1    Perrotte, P.2    Bar-Eli, M.3
  • 30
    • 0036094194 scopus 로고    scopus 로고
    • Enhanced antitumor activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumor xenografts
    • M.C. Prewett, A.T. Hooper, R. Bassi, L.M. Ellis, H.W. Waksal, and D.J. Hicklin Enhanced antitumor activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumor xenografts Clin Cancer Res 8 2002 994 1003 (Pubitemid 34517632)
    • (2002) Clinical Cancer Research , vol.8 , Issue.5 , pp. 994-1003
    • Prewett, M.C.1    Hooper, A.T.2    Bassi, R.3    Ellis, L.M.4    Waksal, H.W.5    Hicklin, D.J.6
  • 31
    • 2142641698 scopus 로고    scopus 로고
    • Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
    • DOI 10.1200/JCO.2004.10.182
    • L.B. Saltz, N.J. Meropol, P.J. Loehrer, M.N. Needle, J. Kopit, and R.J. Mayer Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor J Clin Oncol 22 2004 1201 1208 (Pubitemid 41079832)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.7 , pp. 1201-1208
    • Saltz, L.B.1    Meropol, N.J.2    Loehrer Sr., P.J.3    Needle, M.N.4    Kopit, J.5    Mayer, R.J.6
  • 33
    • 79957528880 scopus 로고    scopus 로고
    • A method for utilizing bivariate efficacy outcome measures to screen agents for activity in 2-stage phase II clinical trials
    • State University of New York at Buffalo Buffalo
    • M.W. Sill, and G. Yothers A method for utilizing bivariate efficacy outcome measures to screen agents for activity in 2-stage phase II clinical trials Technical report 2006 State University of New York at Buffalo Buffalo
    • (2006) Technical Report
    • Sill, M.W.1    Yothers, G.2
  • 34
    • 0000336139 scopus 로고
    • Regression models and life tables
    • D.R. Cox Regression models and life tables J R Stat Soc Ser B 34 1972 187 220
    • (1972) J R Stat Soc ser B , vol.34 , pp. 187-220
    • Cox, D.R.1
  • 35
    • 28044461278 scopus 로고    scopus 로고
    • Gynecologic oncology group trials of chemotherapy for metastatic and recurrent cervical cancer
    • K.S. Tewari, and B.J. Monk Gynecologic oncology group trials of chemotherapy for metastatic and recurrent cervical cancer Curr Oncol Rep 7 2005 419 434 (Pubitemid 41684228)
    • (2005) Current Oncology Reports , vol.7 , Issue.6 , pp. 419-434
    • Tewari, K.S.1    Monk, B.J.2
  • 39
    • 0001407134 scopus 로고    scopus 로고
    • Cetuximab (C225) plus cisplatin/carboplatin is active in patients (pts) with recurrent/metastatic squamous cell carcinoma of the head and neck (SCCHN) progressing on a same dose and schedule platinum-based regimen
    • (Abstract 900)
    • J. Baselga, J. Trigo, and J. Bourhis Cetuximab (C225) plus cisplatin/carboplatin is active in patients (pts) with recurrent/metastatic squamous cell carcinoma of the head and neck (SCCHN) progressing on a same dose and schedule platinum-based regimen Proc Am Soc Clin Oncol 21 2002 226a (Abstract 900)
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Baselga, J.1    Trigo, J.2    Bourhis, J.3
  • 40
    • 34250180582 scopus 로고    scopus 로고
    • Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy
    • DOI 10.1200/JCO.2006.06.7447
    • J.B. Vermorken, J. Trigo, R. Hitt, P. Koralewski, E. Diaz-Rubio, and F. Rolland Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy J Clin Oncol 25 2007 2171 2177 (Pubitemid 46954639)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.16 , pp. 2171-2177
    • Vermorken, J.B.1    Trigo, J.2    Hitt, R.3    Koralewski, P.4    Diaz-Rubio, E.5    Rolland, F.6    Knecht, R.7    Amellal, N.8    Schueler, A.9    Baselga, J.10
  • 41
    • 20144381957 scopus 로고    scopus 로고
    • Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry
    • K.Y. Chung, J. Shia, N.E. Kemeny, M. Shah, G.K. Schwartz, and A. Tse Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry J Clin Oncol 23 2005 1803
    • (2005) J Clin Oncol , vol.23 , pp. 1803
    • Chung, K.Y.1    Shia, J.2    Kemeny, N.E.3    Shah, M.4    Schwartz, G.K.5    Tse, A.6
  • 42
    • 73149105764 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor (EGFR) and activated EGFR predict poor response to (chemo)radiation and survival in cervical cancer
    • M.G. Noordhuis, J.J. Eijsink, K.A. Ten Hoor, F. Roossink, H. Hollema, and H.J. Arts Expression of epidermal growth factor receptor (EGFR) and activated EGFR predict poor response to (chemo)radiation and survival in cervical cancer Clin Cancer Res 15 2009 7389 7397
    • (2009) Clin Cancer Res , vol.15 , pp. 7389-7397
    • Noordhuis, M.G.1    Eijsink, J.J.2    Ten Hoor, K.A.3    Roossink, F.4    Hollema, H.5    Arts, H.J.6
  • 43
    • 52749099497 scopus 로고    scopus 로고
    • Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: A systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
    • H. Linardou, I.J. Dahabreh, D. Kanaloupiti, F. Siannis, D. Bafaloukos, and P. Kosmidis Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer Lancet Oncol 9 2008 962 972
    • (2008) Lancet Oncol , vol.9 , pp. 962-972
    • Linardou, H.1    Dahabreh, I.J.2    Kanaloupiti, D.3    Siannis, F.4    Bafaloukos, D.5    Kosmidis, P.6
  • 44
    • 34249810645 scopus 로고    scopus 로고
    • KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer
    • DOI 10.1158/1078-0432.CCR-06-3043
    • E. Massarelli, M. Varella-Garcia, X. Tang, A.C. Xavier, N.C. Ozburn, and D.D. Liu KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer Clin Cancer Res 13 2007 2890 2896 (Pubitemid 46849563)
    • (2007) Clinical Cancer Research , vol.13 , Issue.10 , pp. 2890-2896
    • Massarelli, E.1    Varella-Garcia, M.2    Tang, X.3    Xavier, A.C.4    Ozburn, N.C.5    Liu, D.D.6    Bekele, B.N.7    Herbst, R.S.8    Wistuba, I.I.9
  • 45
    • 49149127726 scopus 로고    scopus 로고
    • Increased EGFR gene copy number detected by fluorescent in situ hybridization predicts outcome in non-small-cell lung cancer patients treated with cetuximab and chemotherapy
    • F.R. Hirsch, R.S. Herbst, C. Olsen, K. Chansky, J. Crowley, and K. Kelly Increased EGFR gene copy number detected by fluorescent in situ hybridization predicts outcome in non-small-cell lung cancer patients treated with cetuximab and chemotherapy J Clin Oncol 26 2008 3351 3357
    • (2008) J Clin Oncol , vol.26 , pp. 3351-3357
    • Hirsch, F.R.1    Herbst, R.S.2    Olsen, C.3    Chansky, K.4    Crowley, J.5    Kelly, K.6
  • 48
    • 0034837831 scopus 로고    scopus 로고
    • "Low-risk" and "high-risk" HPV-infection and K-ras gene point mutations in human cervical cancer: A study of 31 cases
    • A. Stenzel, A. Semczuk, K. Rozynskal, J. Jakowicki, and J. Wojcierowski "Low-risk" and "high-risk" HPV-infection and K-ras gene point mutations in human cervical cancer: a study of 31 cases Pathol Res Pract 197 2001 597 603 (Pubitemid 32834399)
    • (2001) Pathology Research and Practice , vol.197 , Issue.9 , pp. 597-603
    • Stenzel, A.1    Semczuk, A.2    Roynska, K.3    Jakowicki, J.4    Wojcierowski, J.5
  • 49
    • 0141888073 scopus 로고    scopus 로고
    • Absence of point mutation in codons 12 and 13 of K-RAS oncogene in HPV-associated high grade dysplasia and squamous cell cervical carcinoma
    • DOI 10.1016/S0301-2115(03)00205-7
    • T. Pochylski, and A. Kwasniewska Absence of point mutation in codons 12 and 13 of K-RAS oncogenein HPV-associated high grade dysplasia and squamous cell cervical carcinoma Eur J Obstet Gynecol Reprod Biol 111 2003 68 73 (Pubitemid 37235950)
    • (2003) European Journal of Obstetrics Gynecology and Reproductive Biology , vol.111 , Issue.1 , pp. 68-73
    • Pochylski, T.1    Kwasniewska, A.2
  • 50
    • 34248386122 scopus 로고    scopus 로고
    • Inverse correlation between RASSF1A hypermethylation, KRAS and BRAF mutations in cervical adenocarcinoma
    • DOI 10.1016/j.ygyno.2007.01.045, PII S009082580700100X
    • S. Kang, H.S. Kim, S.S. Seo, S.Y. Park, D. Sidransky, and S.M. Dong Inverse correlation between RASSF1A hypermethylation, KRAS and BRAF mutations in cervical adenocarcinoma Gynecol Oncol 105 2007 662 666 (Pubitemid 46734191)
    • (2007) Gynecologic Oncology , vol.105 , Issue.3 , pp. 662-666
    • Kang, S.1    Kim, H.-S.2    Seo, S.S.3    Park, S.-Y.4    Sidransky, D.5    Dong, S.M.6
  • 52
    • 80051545886 scopus 로고    scopus 로고
    • Cisplatin plus Cetuximab in the treatment of recurrent and persistent cancers of the cervix
    • J.H. Farley, and K.E. Oliver Cisplatin plus Cetuximab in the treatment of recurrent and persistent cancers of the cervix US Oncol Rev 6 2010 45 49
    • (2010) US Oncol Rev , vol.6 , pp. 45-49
    • Farley, J.H.1    Oliver, K.E.2
  • 53
    • 0027818836 scopus 로고
    • Blockade of epidermal growth factor receptor function by bivalent and monovalent fragments of 225 anti-epidermal growth factor receptor monoclonal antibodies
    • Z. Fan, H. Masui, I. Altas, and J. Mendelsohn Blockade of epidermal growth factor receptor function by bivalent and monovalent fragments of 225 anti-epidermal growth factor receptor monoclonal antibodies Cancer Res 53 1993 4322 4328 (Pubitemid 24146785)
    • (1993) Cancer Research , vol.53 , Issue.18 , pp. 4322-4328
    • Fan, Z.1    Masui, H.2    Altas, I.3    Mendelsohn, J.4
  • 54
    • 0034076307 scopus 로고    scopus 로고
    • Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
    • DOI 10.1038/74704
    • R.A. Clynes, T.L. Towers, L.G. Presta, and J.V. Ravetch Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets Nat Med 6 2000 443 446 (Pubitemid 30208162)
    • (2000) Nature Medicine , vol.6 , Issue.4 , pp. 443-446
    • Clynes, R.A.1    Towers, T.L.2    Presta, L.G.3    Ravetch, J.V.4
  • 55
    • 34548124985 scopus 로고    scopus 로고
    • Overexpression of epidermal growth factor type-1 receptor (EGF-R1) in cervical cancer: Implications for Cetuximab-mediated therapy in recurrent/metastatic disease
    • DOI 10.1016/j.ygyno.2007.04.028, PII S0090825807003022
    • S. Bellone, G. Frera, G. Landolfi, C. Romani, E. Bandiera, and G. Tognon Overexpression of epidermal growth factor type-1 receptor (EGF-R1) in cervical cancer: implications for Cetuximab-mediated therapy in recurrent/metastatic disease Gynecol Oncol 106 2007 513 520 (Pubitemid 47302461)
    • (2007) Gynecologic Oncology , vol.106 , Issue.3 , pp. 513-520
    • Bellone, S.1    Frera, G.2    Landolfi, G.3    Romani, C.4    Bandiera, E.5    Tognon, G.6    Roman, J.J.7    Burnett, A.F.8    Pecorelli, S.9    Santin, A.D.10
  • 56
    • 0028868676 scopus 로고
    • Immunocompetent for immunotherapy? A study of the immunocompetence of cervical cancer patients
    • A. Fiander, M. Adams, A.S. Evans, A.J. Bennett, and L.K. Borysiewicz Immunocompetent for immunotherapy? A study of the immunocompetence of cervical cancer patients Int J Gynecol Oncol 5 1995 438 442
    • (1995) Int J Gynecol Oncol , vol.5 , pp. 438-442
    • Fiander, A.1    Adams, M.2    Evans, A.S.3    Bennett, A.J.4    Borysiewicz, L.K.5
  • 57
    • 0034333028 scopus 로고    scopus 로고
    • Effects of concurrent cisplatinum administration during radiotherapy vs. radiotherapy alone on the immune function of patients with cancer of the uterine cervix
    • A.D. Santin, P.L. Hermonat, A. Ravaggi, S. Bellone, J. Roman, and S. Pecorelli Effects of concurrent cisplatinum administration during radiotherapy vs. radiotherapy alone on the immune function of patients with cancer of the uterine cervix Int J Radiat Oncol Biol Phys 48 2000 997 1006
    • (2000) Int J Radiat Oncol Biol Phys , vol.48 , pp. 997-1006
    • Santin, A.D.1    Hermonat, P.L.2    Ravaggi, A.3    Bellone, S.4    Roman, J.5    Pecorelli, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.