Randomised study of radical surgery versus radiotherapy for stage Ib-IIa cervical cancer

Lancet

Volumn 350, Issue 9077, 1997, Pages 535-540

  Landoni, Fabio ^a,d   Maneo, Andrea ^a   Colombo, Alessandro ^b   Placa, Franco ^b   Milani, Rodolfo ^a   Perego, Patrizia ^c   Favini, Giorgio ^c   Ferri, Luigi ^b   Mangioni, Costantino ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b Division of Radiotherapy   (Italy)

^c Ospedale S Gerardo ^*  (Italy)

^d SAN GERARDO HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADJUVANT THERAPY; ADULT; AGED; ARTICLE; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MORBIDITY; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; UTERINE CERVIX CARCINOMA;

EID: 0030875607     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(97)02250-2     Document Type: Article

References (18)

1. Kottmeier HL. Complications following radiation therapy in carcinoma of the cervix and their treatment. Am J Obstet Gynecol 1964; 88: 854-66.
2. Piver MS, Marchetti DL, Patton T, et al. Radical hysterectomy and pelvic lymphadenectomy versus radiation therapy for small (≤3 cm) stage Ib cervical carcinoma. Am J Clin Oncol 1988; 11: 21-24.
3. Morrow PC. Is pelvic radiation beneficial in the postoperative management of stage Ib squamous-cell carcinoma of the cervix with pelvic node metastasis treated by radical hysterectomy and pelvic lymphadenectomy? Gynecol Oncol 1980; 10: 105-10.
4. Kinney WK, Alvarex RD, Reid GC, et al. Value of adjuvant whole-pelvis irradiation after Wertheim hysterectomy for early-stage squamous carcinoma of the cervix with pelvic nodal metastasis: a matched-control study. Gynecol Oncol 1989; 34: 258-62.
5. Newton M. Radical hysterectomy or radiotherapy for stage I cervical cancer. Am J Obstet Gynecol 1975; 123: 535-42.
6. Chassagne D, Gerboulet A, Cosset JM. Intérêt diagnostique de l'empreinte vaginale dans les cancers de l'utérus. J Radiol 1979; 60: 371-73.
7. American Joint Committee on Cancer. Manual for staging of cancer, 4th edn. Philadelphia. J B Lippincott Company, Philadelphia, 1992: 155-57.
8. ICRU (International Commission on Radiation Units and Measurements). Dose and volume specification for reporting intracavitary therapy in gynaecology. ICRU report no 38, Bethesda: ICRU, 1985.
9. Piver MS, Rutledge F, Smith JP. Five classes of extended hysterectomy for women with cervical cancer. Obstet Gynecol 1974; 44: 265-70.
10. Chassagne D, Sismondi P, Horiot JC, et al. A glossary for reporting complications of treatment in gynecological cancers. Radiother Oncol 1993; 26: 195-202.
11. Morley GW, Seski JC. Radical pelvic surgery versus radiation therapy for stage I carcinoma of the cervix (exclusive of microinvasion). Am J Obstet Gynecol 1976; 126: 785-98.
12. Van Nagell JR, Rayburn W, Donaldson ES. Therapeutic implications of pattern of recurrence in cancer of the uterine cervix. Cancer 1979; 44: 2354-61.
13. Piver MS, Chung WS. Prognostic significance of cervical lesion size and pelvic node metastases in cervical carcinoma. Obstet Gynecol 1975; 46: 507-42.
14. Abad R, Kurohara S, Graham J. Clinical significance of adenocarcinoma of the cervix. Am J Obstet Gynecol 1969; 104: 517-22.
15. Ireland D, Hardiman P, Monaghan J. Adenocarcinoma of the uterine cervix: a study of 73 cases, obstet Gynecol 1985; 65: 82-85.
16. Grigsby PW, Perez CA, Kuske RR, et al. Adenocarcinoma of the uterine cervix: lack of evidence for a poor prognosis. Radiother Oncol 1988; 12: 289-96.
17. Kim DS, Moon H, Hwang YY, Cho SH, Preoperative adjuvant chemotherapy in the treatment of cervical cancer stage Ib, IIa and IIb with bulky tumor. Gynecol Oncol 1988; 29: 321-32.
18. Benedetti Panici P, Scambia G, Greggi S, DiRoberto P, Baiocchi G, Mancuso S. Neoadjuvant chemotherapy and radical surgery in locally advanced cervical carcinoma: a pilot study. Obstet Gynecol 1988; 71: 344-48.