-
1
-
-
79959847017
-
Dysregulation of microRNAs in cancer: Playing with fire
-
Melo SA, Esteller M, (2011) Dysregulation of microRNAs in cancer: Playing with fire. FEBS Lett 585: 2087-2099.
-
(2011)
FEBS Lett
, vol.585
, pp. 2087-2099
-
-
Melo, S.A.1
Esteller, M.2
-
2
-
-
58249088751
-
MicroRNAs: target recognition and regulatory functions
-
Bartel DP, (2009) MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
3
-
-
60149084560
-
MicroRNAs and cancer: short RNAs go a long way
-
Ventura A, Jacks T, (2009) MicroRNAs and cancer: short RNAs go a long way. Cell 136: 586-591.
-
(2009)
Cell
, vol.136
, pp. 586-591
-
-
Ventura, A.1
Jacks, T.2
-
4
-
-
33644756685
-
Micro RNAs in animal development
-
Plasterk RH, (2006) Micro RNAs in animal development. Cell 124: 877-881.
-
(2006)
Cell
, vol.124
, pp. 877-881
-
-
Plasterk, R.H.1
-
5
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, et al. (2005) MicroRNA expression profiles classify human cancers. Nature 435: 834-838.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
-
6
-
-
34247593034
-
Impaired microRNA processing enhances cellular transformation and tumorigenesis
-
Kumar MS, Lu J, Mercer KL, Golub TR, Jacks T, (2007) Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet 39: 673-677.
-
(2007)
Nat Genet
, vol.39
, pp. 673-677
-
-
Kumar, M.S.1
Lu, J.2
Mercer, K.L.3
Golub, T.R.4
Jacks, T.5
-
7
-
-
61349127117
-
A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function
-
Melo SA, Ropero S, Moutinho C, Aaltonen LA, Yamamoto H, et al. (2009) A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function. Nat Genet 41: 365-370.
-
(2009)
Nat Genet
, vol.41
, pp. 365-370
-
-
Melo, S.A.1
Ropero, S.2
Moutinho, C.3
Aaltonen, L.A.4
Yamamoto, H.5
-
8
-
-
77951785861
-
EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells
-
Riggi N, Suva ML, De Vito C, Provero P, Stehle JC, et al. (2010) EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells. Genes Dev 24: 916-932.
-
(2010)
Genes Dev
, vol.24
, pp. 916-932
-
-
Riggi, N.1
Suva, M.L.2
de Vito, C.3
Provero, P.4
Stehle, J.C.5
-
9
-
-
34447324657
-
The Biology of Ewing sarcoma
-
Riggi N, Stamenkovic I, (2007) The Biology of Ewing sarcoma. Cancer Lett 254: 1-10.
-
(2007)
Cancer Lett
, vol.254
, pp. 1-10
-
-
Riggi, N.1
Stamenkovic, I.2
-
10
-
-
29244447707
-
Development of Ewing's sarcoma from primary bone marrow-derived mesenchymal progenitor cells
-
Riggi N, Cironi L, Provero P, Suva ML, Kaloulis K, et al. (2005) Development of Ewing's sarcoma from primary bone marrow-derived mesenchymal progenitor cells. Cancer Res 65: 11459-11468.
-
(2005)
Cancer Res
, vol.65
, pp. 11459-11468
-
-
Riggi, N.1
Cironi, L.2
Provero, P.3
Suva, M.L.4
Kaloulis, K.5
-
11
-
-
42049089299
-
EWS-FLI-1 expression triggers a Ewing's sarcoma initiation program in primary human mesenchymal stem cells
-
Riggi N, Suva ML, Suva D, Cironi L, Provero P, et al. (2008) EWS-FLI-1 expression triggers a Ewing's sarcoma initiation program in primary human mesenchymal stem cells. Cancer Res 68: 2176-2185.
-
(2008)
Cancer Res
, vol.68
, pp. 2176-2185
-
-
Riggi, N.1
Suva, M.L.2
Suva, D.3
Cironi, L.4
Provero, P.5
-
12
-
-
34247570879
-
Mesenchymal stem cell features of ewing tumors
-
Tirode F, Laud-Duval K, Prieur A, Delorme B, Charbord P, et al. (2007) Mesenchymal stem cell features of ewing tumors. Cancer Cell 11: 421-429.
-
(2007)
Cancer Cell
, vol.11
, pp. 421-429
-
-
Tirode, F.1
Laud-Duval, K.2
Prieur, A.3
Delorme, B.4
Charbord, P.5
-
13
-
-
41949102707
-
miRiad roles for the miR-17-92 cluster in development and disease
-
Mendell JT, (2008) miRiad roles for the miR-17-92 cluster in development and disease. Cell 133: 217-222.
-
(2008)
Cell
, vol.133
, pp. 217-222
-
-
Mendell, J.T.1
-
14
-
-
50549095181
-
Let-7 microRNAs in development, stem cells and cancer
-
Bussing I, Slack FJ, Grosshans H, (2008) let-7 microRNAs in development, stem cells and cancer. Trends Mol Med 14: 400-409.
-
(2008)
Trends Mol Med
, vol.14
, pp. 400-409
-
-
Bussing, I.1
Slack, F.J.2
Grosshans, H.3
-
15
-
-
36849078711
-
Let-7 regulates self renewal and tumorigenicity of breast cancer cells
-
Yu F, Yao H, Zhu P, Zhang X, Pan Q, et al. (2007) let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 131: 1109-1123.
-
(2007)
Cell
, vol.131
, pp. 1109-1123
-
-
Yu, F.1
Yao, H.2
Zhu, P.3
Zhang, X.4
Pan, Q.5
-
16
-
-
77952893906
-
CD133 expression in chemo-resistant Ewing sarcoma cells
-
Jiang X, Gwye Y, Russell D, Cao C, Douglas D, et al. (2010) CD133 expression in chemo-resistant Ewing sarcoma cells. BMC Cancer 10: 116.
-
(2010)
BMC Cancer
, vol.10
, pp. 116
-
-
Jiang, X.1
Gwye, Y.2
Russell, D.3
Cao, C.4
Douglas, D.5
-
17
-
-
67649881121
-
Lin28 promotes transformation and is associated with advanced human malignancies
-
Viswanathan SR, Powers JT, Einhorn W, Hoshida Y, Ng TL, et al. (2009) Lin28 promotes transformation and is associated with advanced human malignancies. Nat Genet 41: 843-848.
-
(2009)
Nat Genet
, vol.41
, pp. 843-848
-
-
Viswanathan, S.R.1
Powers, J.T.2
Einhorn, W.3
Hoshida, Y.4
Ng, T.L.5
-
18
-
-
65249101694
-
EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation
-
Richter GH, Plehm S, Fasan A, Rossler S, Unland R, et al. (2009) EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation. Proc Natl Acad Sci U S A 106: 5324-5329.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 5324-5329
-
-
Richter, G.H.1
Plehm, S.2
Fasan, A.3
Rossler, S.4
Unland, R.5
-
19
-
-
42049103216
-
The let-7 microRNA reduces tumor growth in mouse models of lung cancer
-
Esquela-Kerscher A, Trang P, Wiggins JF, Patrawala L, Cheng A, et al. (2008) The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle 7: 759-764.
-
(2008)
Cell Cycle
, vol.7
, pp. 759-764
-
-
Esquela-Kerscher, A.1
Trang, P.2
Wiggins, J.F.3
Patrawala, L.4
Cheng, A.5
-
20
-
-
67749143728
-
Modulation of microRNA processing by p53
-
Suzuki HI, Yamagata K, Sugimoto K, Iwamoto T, Kato S, et al. (2009) Modulation of microRNA processing by p53. Nature 460: 529-533.
-
(2009)
Nature
, vol.460
, pp. 529-533
-
-
Suzuki, H.I.1
Yamagata, K.2
Sugimoto, K.3
Iwamoto, T.4
Kato, S.5
-
21
-
-
0030783770
-
Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors
-
Kovar H, Jug G, Aryee DN, Zoubek A, Ambros P, et al. (1997) Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors. Oncogene 15: 2225-2232.
-
(1997)
Oncogene
, vol.15
, pp. 2225-2232
-
-
Kovar, H.1
Jug, G.2
Aryee, D.N.3
Zoubek, A.4
Ambros, P.5
-
22
-
-
77953554439
-
miR-31: A crucial overseer of tumor metastasis and other emerging roles
-
Valastyan S, Weinberg RA, (2010) miR-31: A crucial overseer of tumor metastasis and other emerging roles. Cell Cycle 9.
-
(2010)
Cell Cycle
, vol.9
-
-
Valastyan, S.1
Weinberg, R.A.2
-
23
-
-
66449095667
-
A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis
-
Valastyan S, Reinhardt F, Benaich N, Calogrias D, Szasz AM, et al. (2009) A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell 137: 1032-1046.
-
(2009)
Cell
, vol.137
, pp. 1032-1046
-
-
Valastyan, S.1
Reinhardt, F.2
Benaich, N.3
Calogrias, D.4
Szasz, A.M.5
-
24
-
-
41649096450
-
Identification of let-7-regulated oncofetal genes
-
Boyerinas B, Park SM, Shomron N, Hedegaard MM, Vinther J, et al. (2008) Identification of let-7-regulated oncofetal genes. Cancer Res 68: 2587-2591.
-
(2008)
Cancer Res
, vol.68
, pp. 2587-2591
-
-
Boyerinas, B.1
Park, S.M.2
Shomron, N.3
Hedegaard, M.M.4
Vinther, J.5
-
25
-
-
41649114199
-
Suppression of non-small cell lung tumor development by the let-7 microRNA family
-
Kumar MS, Erkeland SJ, Pester RE, Chen CY, Ebert MS, et al. (2008) Suppression of non-small cell lung tumor development by the let-7 microRNA family. Proc Natl Acad Sci U S A 105: 3903-3908.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 3903-3908
-
-
Kumar, M.S.1
Erkeland, S.J.2
Pester, R.E.3
Chen, C.Y.4
Ebert, M.S.5
-
26
-
-
77449133843
-
The role of let-7 in cell differentiation and cancer
-
Boyerinas B, Park SM, Hau A, Murmann AE, Peter ME, (2010) The role of let-7 in cell differentiation and cancer. Endocr Relat Cancer 17: F19-36.
-
(2010)
Endocr Relat Cancer
, vol.17
, pp. 19-36
-
-
Boyerinas, B.1
Park, S.M.2
Hau, A.3
Murmann, A.E.4
Peter, M.E.5
-
27
-
-
48249127913
-
Microsatellites as EWS/FLI response elements in Ewing's sarcoma
-
Gangwal K, Sankar S, Hollenhorst PC, Kinsey M, Haroldsen SC, et al. (2008) Microsatellites as EWS/FLI response elements in Ewing's sarcoma. Proc Natl Acad Sci U S A 105: 10149-10154.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 10149-10154
-
-
Gangwal, K.1
Sankar, S.2
Hollenhorst, P.C.3
Kinsey, M.4
Haroldsen, S.C.5
-
28
-
-
47949100595
-
Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
-
Newman MA, Thomson JM, Hammond SM, (2008) Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA 14: 1539-1549.
-
(2008)
RNA
, vol.14
, pp. 1539-1549
-
-
Newman, M.A.1
Thomson, J.M.2
Hammond, S.M.3
-
29
-
-
40849108663
-
Selective blockade of microRNA processing by Lin28
-
Viswanathan SR, Daley GQ, Gregory RI, (2008) Selective blockade of microRNA processing by Lin28. Science 320: 97-100.
-
(2008)
Science
, vol.320
, pp. 97-100
-
-
Viswanathan, S.R.1
Daley, G.Q.2
Gregory, R.I.3
-
30
-
-
53949088050
-
Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA
-
Heo I, Joo C, Cho J, Ha M, Han J, et al. (2008) Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA. Mol Cell 32: 276-284.
-
(2008)
Mol Cell
, vol.32
, pp. 276-284
-
-
Heo, I.1
Joo, C.2
Cho, J.3
Ha, M.4
Han, J.5
-
31
-
-
77955425756
-
Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis
-
Michlewski G, Caceres JF, (2010) Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis. Nature structural & molecular biology 17: 1011-1018.
-
(2010)
Nature Structural & Molecular Biology
, vol.17
, pp. 1011-1018
-
-
Michlewski, G.1
Caceres, J.F.2
-
32
-
-
36448992338
-
Roles of HMGA proteins in cancer
-
Fusco A, Fedele M, (2007) Roles of HMGA proteins in cancer. Nat Rev Cancer 7: 899-910.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 899-910
-
-
Fusco, A.1
Fedele, M.2
-
33
-
-
42149187083
-
HMGA2 is the partner of MDM2 in well-differentiated and dedifferentiated liposarcomas whereas CDK4 belongs to a distinct inconsistent amplicon
-
Italiano A, Bianchini L, Keslair F, Bonnafous S, Cardot-Leccia N, et al. (2008) HMGA2 is the partner of MDM2 in well-differentiated and dedifferentiated liposarcomas whereas CDK4 belongs to a distinct inconsistent amplicon. Int J Cancer 122: 2233-2241.
-
(2008)
Int J Cancer
, vol.122
, pp. 2233-2241
-
-
Italiano, A.1
Bianchini, L.2
Keslair, F.3
Bonnafous, S.4
Cardot-Leccia, N.5
-
34
-
-
77955022405
-
Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34
-
Wiggins JF, Ruffino L, Kelnar K, Omotola M, Patrawala L, et al. (2010) Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34. Cancer Res 70: 5923-5930.
-
(2010)
Cancer Res
, vol.70
, pp. 5923-5930
-
-
Wiggins, J.F.1
Ruffino, L.2
Kelnar, K.3
Omotola, M.4
Patrawala, L.5
-
35
-
-
77950665077
-
Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model
-
Ma L, Reinhardt F, Pan E, Soutschek J, Bhat B, et al. (2010) Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model. Nat Biotechnol 28: 341-347.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 341-347
-
-
Ma, L.1
Reinhardt, F.2
Pan, E.3
Soutschek, J.4
Bhat, B.5
-
36
-
-
20444479428
-
c-Myc-regulated microRNAs modulate E2F1 expression
-
O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT, (2005) c-Myc-regulated microRNAs modulate E2F1 expression. Nature 435: 839-843.
-
(2005)
Nature
, vol.435
, pp. 839-843
-
-
O'Donnell, K.A.1
Wentzel, E.A.2
Zeller, K.I.3
Dang, C.V.4
Mendell, J.T.5
-
37
-
-
37549008310
-
Widespread microRNA repression by Myc contributes to tumorigenesis
-
Chang TC, Yu D, Lee YS, Wentzel EA, Arking DE, et al. (2008) Widespread microRNA repression by Myc contributes to tumorigenesis. Nat Genet 40: 43-50.
-
(2008)
Nat Genet
, vol.40
, pp. 43-50
-
-
Chang, T.C.1
Yu, D.2
Lee, Y.S.3
Wentzel, E.A.4
Arking, D.E.5
-
38
-
-
37549032427
-
Do cells let-7 determine stemness?
-
Droge P, Davey CA, (2008) Do cells let-7 determine stemness? Cell Stem Cell 2: 8-9.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 8-9
-
-
Droge, P.1
Davey, C.A.2
-
39
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, et al. (2007) Induced pluripotent stem cell lines derived from human somatic cells. Science 318: 1917-1920.
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
Antosiewicz-Bourget, J.4
Frane, J.L.5
-
40
-
-
78549261109
-
Double-Negative Feedback Loop between Reprogramming Factor LIN28 and microRNA let-7 Regulates Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells
-
Yang X, Lin X, Zhong X, Kaur S, Li N, et al. (2010) Double-Negative Feedback Loop between Reprogramming Factor LIN28 and microRNA let-7 Regulates Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells. Cancer Res 70: 9463-9472.
-
(2010)
Cancer Res
, vol.70
, pp. 9463-9472
-
-
Yang, X.1
Lin, X.2
Zhong, X.3
Kaur, S.4
Li, N.5
-
41
-
-
78649728590
-
High ALDH Activity Identifies Chemotherapy-Resistant Ewing's Sarcoma Stem Cells That Retain Sensitivity to EWS-FLI1 Inhibition
-
Awad O, Yustein JT, Shah P, Gul N, Katuri V, et al. (2010) High ALDH Activity Identifies Chemotherapy-Resistant Ewing's Sarcoma Stem Cells That Retain Sensitivity to EWS-FLI1 Inhibition. PLoS One 5: e13943.
-
(2010)
PLoS One
, vol.5
-
-
Awad, O.1
Yustein, J.T.2
Shah, P.3
Gul, N.4
Katuri, V.5
-
42
-
-
78649689358
-
Value and limitation of immunohistochemical expression of HMGA2 in mesenchymal tumors: about a series of 1052 cases
-
Dreux N, Marty M, Chibon F, Velasco V, Hostein I, et al. (2010) Value and limitation of immunohistochemical expression of HMGA2 in mesenchymal tumors: about a series of 1052 cases. Mod Pathol.
-
(2010)
Mod Pathol
-
-
Dreux, N.1
Marty, M.2
Chibon, F.3
Velasco, V.4
Hostein, I.5
-
43
-
-
77955396951
-
Identification of target genes for wild type and truncated HMGA2 in mesenchymal stem-like cells
-
Henriksen J, Stabell M, Meza-Zepeda LA, Lauvrak SA, Kassem M, et al. (2010) Identification of target genes for wild type and truncated HMGA2 in mesenchymal stem-like cells. BMC Cancer 10: 329.
-
(2010)
BMC Cancer
, vol.10
, pp. 329
-
-
Henriksen, J.1
Stabell, M.2
Meza-Zepeda, L.A.3
Lauvrak, S.A.4
Kassem, M.5
-
44
-
-
53749098061
-
Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression
-
Nishino J, Kim I, Chada K, Morrison SJ, (2008) Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression. Cell 135: 227-239.
-
(2008)
Cell
, vol.135
, pp. 227-239
-
-
Nishino, J.1
Kim, I.2
Chada, K.3
Morrison, S.J.4
|