Dramatic loss of Ube3A expression during aging of the mammalian cortex

Frontiers in Aging Neuroscience

Volumn 2, Issue MAY, 2010, Pages

  Williams, Kate ^a   Irwin, David A ^a   Jones, David G ^a   Murphy, Kathryn M ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Aging; E6AP; Plasticity; Ube3A; Visual cortex

Indexed keywords

EID: 80051529838     PISSN: None     EISSN: 16634365     Source Type: Journal    
DOI: 10.3389/fnagi.2010.00018     Document Type: Article

References (28)

1. Ardley, H., and Robinson, P. (2004). The role of ubiquitin-protein ligases in neurodegenerative disease. Neurodegener. Dis. 1, 71-87.
2. Bai, L., Hof, P., Standaert, D., Xing, Y., Nelson, S., Young, A., and Magnusson, K. (2004). Changes in the expression of the NR2B subunit during aging in macaque monkeys. Neurobiol. Aging, 25, 201-208.
3. Betts, L., Taylor, C., Sekuler, A., and Bennett, P. (2005). Aging reduces center-surround antagonism in visual motion processing. Neuron 45, 361-366.
4. Billino, J., Bremmer, F., and Gegenfurtner, K. (2008). Differential aging of motion processing mechanisms: evidence against general perceptual decline. Vision Res. 48, 1254-1261.
5. Burke, S., and Barnes, C. (2006). Neural plasticity in the ageing brain. Nat. Rev. Neurosci. 7, 30-40.
6. Carrano, A., Liu, Z., Dillin, A., and Hunter, T. (2009). A conserved ubiquitination pathway determines longevity in response to diet restriction. Nature 460, 396-399.
7. Cline, H. (2003). Synaptic plasticity: importance of proteasome-mediated protein turnover. Curr. Biol. 13, R514-R516.
8. DiAntonio, A., and Hicke, L. (2004). Ubiquitin-dependent regulation of the synapse. Annu. Rev. Neurosci. 27, 223-246.
9. Dindot, S., Antalffy, B., Bhattacharjee, M., and Beaudet, A. (2008). The angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology. Hum. Mol. Genet. 17, 111-118.
10. Ehlers, M. (2003). Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system. Nat. Neurosci. 6, 231-242.
11. Faubert, J. (2002). Visual perception and aging. Can. J. Exp. Psychol. 56, 164-176.
12. Fratiglioni, L., Paillard-Borg, S., and Winblad, B. (2004). An active and socially integrated lifestyle in late life might protect against dementia. Lancet Neurol. 3, 343-353.
13. Fu, Y., Djupsund, K., Gao, H., Hayden, B., Shen, K., and Dan, Y. (2002). Temporal specificity in the cortical plasticity of visual space representation. Science 296, 1999-2003.
14. Greer, P. L., Hanayama, R., Bloodgood, B. L., Mardinly, A. R., Lipton, D. M., Flavell, S. W., Kim, T. K., Griffith, E. C., Waldon, Z., Maehr, R., Ploegh, H. L., Chowdbury, S., Worley, P. F., Steen, J., and Greenberg, M. E. (2010). The Angelman Syndrome protein Ube3a regulates synapse development by ubiquitinating arc. Cell 140, 704-716.
15. Habak, C., and Faubert, J. (2000). Larger effect of aging on the perception of higher-order stimuli. Vision Res. 40, 943-950.
16. Hensch, T. K., Fagiolini, M., Mataga, N., Stryker, M. P., Baekkeskov, S., and Kash, S. F. (1998). Local GABA circuit control of experience-dependent plasticity in developing visual cortex. Science 282, 1504-1508.
17. Hua, T., Kao, C., Sun, Q., Li, X., and Zhou, Y. (2008). Decreased proportion of GABA neurons accompanies age-related degradation of neuronal function in cat striate cortex. Brain Res. Bull. 75, 119-125.
18. Jiang, Y. H., Armstrong, D., Albrecht, U., Atkins, C. M., Noebels, J. L., Eichele, G., Sweat, J. D., and Beaudet, A. L. (1998). Mutation of the angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation. Neuron 21, 799-811.
19. Kishino, T., Lalande, M., and Wagstaff, J. (1997). Ube3A/E6-AP mutations cause Angelman syndrome. Nat. Genet. 15, 70-73.
20. Leventhal, A., Wang, Y., Pu, M., Zhou, Y., and Ma, Y. (2003). GABA and its agonists improved visual cortical function in senescent monkeys. Science 300, 812-815.
21. Pinto, J. G., Hornby, K. R., Jones, D. G., and Murphy, K. M. (2010). Developmental changes in GABAergic mechanisms in human visual cortex across the lifespan. Front. Cell. Neurosci. (in press).
22. Sato, M., and Stryker, M. P. (2008). Distinctive features of adult ocular dominance plasticity. J. Neurosci. 28, 10278-10286.
23. Sato, M., and Stryker, M. P. (2010). Genomic Imprinting of experience-dependent cortical plasticity by the ubiquitin ligase gene Ube3a. Proc. Natl. Acad. Sci. 107, 5611-5616.
24. Schmolesky, M. T., Wang, Y., Pu, M., and Leventhal, A. G. (2000). Degradation of stimulus selectivity of visual cortical cells in senescent rhesus monkeys. Nat. Neurosci. 3, 384-390.
25. Sekuler, A. B., Bennett, P. J., and Mamelak, M. (2000). Effects of aging on the useful field of view. Exp. Aging Res. 26, 103-120.
26. Tusa, R. J., Palmer, L. A., and Rosenquist, A. C. (1978). The retinotopic organization of area 17 (striate cortex) in the cat. J. Comp. Neurol. 177, 213-235.
27. Wong, T. P., Marchese, G., Casu, M. A., Ribeiro-da-Silva, A., Cuello, A. C., and De Koninck, Y. (2000). Loss of presynaptic and postsynaptic structures is accompanied by compensatory increase in action potential-dependent synaptic input to layer V neocortical pyramidal neurons in aged rats. J. Neurosci. 20, 8596-8606.
28. Yashiro, K., Riday, T., Condon, K., Roberts, A., Bernardo, D., Prakash, R., Weinberg, R., Ehlers, M., and Philpot, B. (2009). Ube3A is required for experience-dependent maturation of the neocortex. Nat. Neurosci. 12, 777-783.