메뉴 건너뛰기




Volumn 32, Issue 8, 2011, Pages 1009-1018

Vasorelaxant and antihypertensive effects of formononetin through endothelium-dependent and -independent mechanisms

Author keywords

arterial rings; blood pressure; formononetin; intracellular Ca 2+ release; nitric oxide; spontaneously hypertensive rats; vasodilatation; voltage dependent Ca 2+ channel

Indexed keywords

CALCIUM ION; FORMONONETIN; LACIDIPINE; NITRIC OXIDE; VOLTAGE GATED CALCIUM CHANNEL;

EID: 80051526773     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.51     Document Type: Article
Times cited : (57)

References (45)
  • 2
    • 71749103940 scopus 로고    scopus 로고
    • Antihypertensive effects of Hsian-tsao and its active compound in spontaneously hypertensive rats
    • Yeh CT, Huang WH, Yen GC. Antihypertensive effects of Hsian-tsao and its active compound in spontaneously hypertensive rats. J Nutr Biochem 2009; 20: 866-75.
    • (2009) J Nutr Biochem , vol.20 , pp. 866-75
    • Yeh, C.T.1    Huang, W.H.2    Yen, G.C.3
  • 3
    • 0029559277 scopus 로고
    • Vascular effects of selected antihypertensive drugs derived from traditional medicinal herbs
    • Kwan CY. Vascular effects of selected antihypertensive drugs derived from traditional medicinal herbs. Clin Exp Pharmacol Physiol Suppl 1995; 22: S297-9.
    • (1995) Clin Exp Pharmacol Physiol Suppl , vol.22
    • Kwan, C.Y.1
  • 4
    • 45449106577 scopus 로고    scopus 로고
    • Antihypertensive, vasorelaxant and inotropic effects of an ethanolic extract of the roots of Saururus chinensis
    • Ryu SY, Oh KS, Kim YS, Lee BH. Antihypertensive, vasorelaxant and inotropic effects of an ethanolic extract of the roots of Saururus chinensis. J Ethnopharmacol 2008; 118: 284-9.
    • (2008) J Ethnopharmacol , vol.118 , pp. 284-9
    • Ryu, S.Y.1    Oh, K.S.2    Kim, Y.S.3    Lee, B.H.4
  • 7
    • 34247176729 scopus 로고    scopus 로고
    • An isoflavone metabolite reduces arterial stiffness and blood pressure in overweight men and postmenopausal women
    • DOI 10.1016/j.atherosclerosis.2006.04.033, PII S0021915006002528
    • Nestel P, Fujii A, Zhang L. An isoflavone metabolite reduces arterial stiffness and blood pressure in overweight men and postmenopausal women. Atherosclerosis 2007; 192: 184-9. (Pubitemid 46602296)
    • (2007) Atherosclerosis , vol.192 , Issue.1 , pp. 184-189
    • Nestel, P.1    Fujii, A.2    Zhang, L.3
  • 8
    • 0141829776 scopus 로고    scopus 로고
    • Phytoestrogens: A review of the present state of research
    • Ososki AL, Kennelly EJ. Phytoestrogens: A review of the present state of research. Phytother Res 2003; 17: 845-69.
    • (2003) Phytother Res , vol.17 , pp. 845-69
    • Ososki, A.L.1    Kennelly, E.J.2
  • 9
    • 77953812949 scopus 로고    scopus 로고
    • Formononetin, an isoflavone, relaxes rat isolated aorta through endothelium-dependent and endothelium-independent pathways
    • Wu JH, Li Q, Wu MY, Guo DJ, Chen HL, Chen SL, et al. Formononetin, an isoflavone, relaxes rat isolated aorta through endothelium-dependent and endothelium-independent pathways. J Nutr Biochem 2009; 21: 613-20.
    • (2009) J Nutr Biochem , vol.21 , pp. 613-20
    • Wu, J.H.1    Li, Q.2    Wu, M.Y.3    Guo, D.J.4    Chen, H.L.5    Chen, S.L.6
  • 10
    • 4043111225 scopus 로고    scopus 로고
    • The isoflavone metabolite dehydroequol produces vasodilatation in human resistance arteries via a nitric oxide-dependent mechanism
    • DOI 10.1016/j.atherosclerosis.2004.03.025, PII S0021915004002370
    • Chin-Dusting JP, Boak L, Husband A, Nestel PJ. The isoflavone metabolite dehydroequol produces vasodilatation in human resistance arteries via a nitric oxide-dependent mechanism. Atherosclerosis 2004; 176: 45-8. (Pubitemid 39078643)
    • (2004) Atherosclerosis , vol.176 , Issue.1 , pp. 45-48
    • Chin-Dusting, J.P.F.1    Boak, L.2    Husband, A.3    Nestel, P.J.4
  • 12
    • 0033867027 scopus 로고    scopus 로고
    • Estrogenic activity of flavonoids in mice. The importance of estrogen receptor distribution, metabolism and bioavailability
    • DOI 10.1016/S0278-6915(00)00046-6, PII S0278691500000466
    • Breinholt V, Hossaini A, Svendsen GW, Brouwer C, Nielsen E. Estrogenic activity of flavonoids in mice. The importance of estrogen receptor distribution, metabolism and bioavailability. Food Chem Toxicol 2000; 38: 555-64. (Pubitemid 30624135)
    • (2000) Food and Chemical Toxicology , vol.38 , Issue.7 , pp. 555-564
    • Breinholt, V.1    Hossaini, A.2    Svendsen, G.W.3    Brouwer, C.4    Nielsen, S.E.5
  • 13
    • 0029776049 scopus 로고    scopus 로고
    • Phytoestrogen content of foods - A compendium of literature values
    • Reinli K, Block G. Phytoestrogen content of foods - a compendium of literature values. Nutr Cancer 1996; 26: 123-48. (Pubitemid 26300193)
    • (1996) Nutrition and Cancer , vol.26 , Issue.2 , pp. 123-148
    • Reinli, K.1    Block, G.2
  • 14
    • 0032116898 scopus 로고    scopus 로고
    • Potential health benefits of dietary phytoestrogens: A review of the clinical, epidemiological, and mechanistic evidence
    • DOI 10.1210/jc.83.7.2223
    • Tham DM, Gardner CD, Haskell WL. Clinical review 97: Potential health benefits of dietary phytoestrogens: A review of the clinical, epidemiological, and mechanistic evidence. J Clin Endocrinol Metab 1998; 83: 2223-35. (Pubitemid 28503006)
    • (1998) Journal of Clinical Endocrinology and Metabolism , vol.83 , Issue.7 , pp. 2223-2235
    • Tham, D.M.1    Gardner, C.D.2    Haskell, W.L.3
  • 16
    • 0035895323 scopus 로고    scopus 로고
    • The phytoestrogen genistein produces acute nitric oxide-dependent dilation of human forearm vasculature with similar potency to 17βestradiol
    • Walker HA, Dean TS, Sanders TA, Jackson G, Ritter JM, Chowienczyk PJ. The phytoestrogen genistein produces acute nitric oxidedependent dilation of human forearm vasculature with similar potency to 17beta-estradiol. Circulation 2001; 103: 258-62. (Pubitemid 32095412)
    • (2001) Circulation , vol.103 , Issue.2 , pp. 258-262
    • Walker, H.A.1    Dean, T.S.2    Sanders, T.A.B.3    Jackson, G.4    Ritter, J.M.5    Chowienczyk, P.J.6
  • 17
    • 36049007935 scopus 로고    scopus 로고
    • Combined effects of fangchinoline from Stephania tetrandra Radix and formononetin and calycosin from Astragalus membranaceus radix on hyperglycemia and hypoinsulinemia in streptozotocin-diabetic mice
    • DOI 10.1248/bpb.30.2079
    • Ma W, Nomura M, Takahashi-Nishioka T, Kobayashi S. Combined effects of fangchinoline from Stephania tetrandra Radix and formononetin and calycosin from Astragalus membranaceus Radix on hyperglycemia and hypoinsulinemia in streptozotocin-diabetic mice. Biol Pharm Bull 2007; 30: 2079-83. (Pubitemid 350097043)
    • (2007) Biological and Pharmaceutical Bulletin , vol.30 , Issue.11 , pp. 2079-2083
    • Ma, W.1    Nomura, M.2    Takahashi-Nishioka, T.3    Kobayashi, S.4
  • 18
    • 56149127357 scopus 로고    scopus 로고
    • Preparative isolation and purification of calycosin and formononetin from Astragalus membranaceus Bge var mongholicus (Bge) Hsiao by high-speed counter-current chromatography
    • Ma X, Tu P, Chen Y, Zhang T, Wei Y. Preparative isolation and purification of calycosin and formononetin from Astragalus membranaceus Bge var mongholicus (Bge) Hsiao by high-speed counter-current chromatography. Se Pu 2005; 23: 299-301.
    • (2005) Se Pu , vol.23 , pp. 299-301
    • Ma, X.1    Tu, P.2    Chen, Y.3    Zhang, T.4    Wei, Y.5
  • 19
    • 34250512454 scopus 로고
    • 7-hydroxy-4'-methoxy-isoflavone (formononetin) from liquorice root. On substances contained in liquorice root. II
    • Reiners W. 7-hydroxy-4'-methoxy-isoflavone (formononetin) from liquorice root. On substances contained in liquorice root. II. Experientia 1966; 22: 359.
    • (1966) Experientia , vol.22 , pp. 359
    • Reiners, W.1
  • 20
    • 65649126296 scopus 로고    scopus 로고
    • Quantitative determination of triterpenoids and formononetin in rhizomes of black cohosh (Actaea racemosa) and dietary supplements by using UPLC-UV/ELS detection and identification by UPLC-MS
    • Avula B, Wang YH, Smillie TJ, Khan IA. Quantitative determination of triterpenoids and formononetin in rhizomes of black cohosh (Actaea racemosa) and dietary supplements by using UPLC-UV/ELS detection and identification by UPLC-MS. Planta Med 2009; 75: 381-6.
    • (2009) Planta Med , vol.75 , pp. 381-6
    • Avula, B.1    Wang, Y.H.2    Smillie, T.J.3    Khan, I.A.4
  • 21
    • 33744503581 scopus 로고    scopus 로고
    • Analysis of formononetin from black cohosh (Actaea racemosa)
    • DOI 10.1016/j.phymed.2005.06.007, PII S0944711305002011
    • Jiang B, Kronenberg F, Balick MJ, Kennelly EJ. Analysis of formononetin from black cohosh (Actaea racemosa). Phytomedicine 2006; 13: 477-86. (Pubitemid 43922399)
    • (2006) Phytomedicine , vol.13 , Issue.7 , pp. 477-486
    • Jiang, B.1    Kronenberg, F.2    Balick, M.J.3    Kennelly, E.J.4
  • 22
    • 34250942301 scopus 로고
    • Isoflavone glucoside formononetin-7-glucoside and biochanin A-7-glucoside in Trifolium pratense L
    • Schultz G. Isoflavone glucoside formononetin-7-glucoside and biochanin A-7-glucoside in Trifolium pratense L. Naturwissenschaften 1965; 52: 517.
    • (1965) Naturwissenschaften , Issue.52 , pp. 517
    • Schultz, G.1
  • 23
    • 33846451021 scopus 로고    scopus 로고
    • Effects of Astragalus membranaceus and its main components on the acute phase endothelial dysfunction induced by homocysteine
    • DOI 10.1016/j.vph.2006.11.001, PII S1537189106006306
    • Zhang BQ, Hu SJ, Qiu LH, Zhu JH, Xie XJ, Sun J, et al. Effects of Astragalus membranaceus and its main components on the acute phase endothelial dysfunction induced by homocysteine. Vasc Pharmacol 2007; 46: 278-85. (Pubitemid 46138051)
    • (2007) Vascular Pharmacology , vol.46 , Issue.4 , pp. 278-285
    • Zhang, B.-Q.1    Hu, S.-J.2    Qiu, L.-H.3    Zhu, J.-h.4    Xie, X.-J.5    Sun, J.6    Zhu, Z.-H.7    Xia, Q.8    Bian, K.9
  • 24
    • 0029853692 scopus 로고    scopus 로고
    • Plasticity of contractile endothelin-B receptors in human arteries after organ culture
    • Adner M, Cantera L, Ehlert F, Nilsson L, Edvinsson L. Plasticity of contractile endothelin-B receptors in human arteries after organ culture. Br J Pharmacol 1996; 119: 1159-66. (Pubitemid 26385986)
    • (1996) British Journal of Pharmacology , vol.119 , Issue.6 , pp. 1159-1166
    • Adner, M.1    Cantera, L.2    Ehlert, F.3    Nilsson, L.4    Edvinsson, L.5
  • 25
    • 77957869032 scopus 로고    scopus 로고
    • Upregulation of contractile endothelin type B receptors by lipid-soluble cigarette smoking particles in rat cerebral arteries via activation of MAPK
    • Sandhu H, Xu CB, Edvinsson L. Upregulation of contractile endothelin type B receptors by lipid-soluble cigarette smoking particles in rat cerebral arteries via activation of MAPK. Toxicol Appl Pharmacol 2010; 249: 25-32.
    • (2010) Toxicol Appl Pharmacol , vol.249 , pp. 25-32
    • Sandhu, H.1    Xu, C.B.2    Edvinsson, L.3
  • 27
    • 33750919945 scopus 로고    scopus 로고
    • 2+ influx and release
    • DOI 10.1016/j.vph.2006.05.004, PII S1537189106001182
    • Cao YX, Zhang W, He JY, He LC, Xu CB. Ligustilide induces vasodilatation via inhibiting voltage dependent calcium channel and receptormediated Ca2+ influx and release. Vascul Pharmacol 2006; 45: 171-6. (Pubitemid 44724952)
    • (2006) Vascular Pharmacology , vol.45 , Issue.3 , pp. 171-176
    • Cao, Y.-X.1    Zhang, W.2    He, J.-Y.3    He, L.-C.4    Xu, C.-B.5
  • 28
    • 32444441011 scopus 로고    scopus 로고
    • Enhanced Y1-receptor-mediated vasoconstrictive action of neuropeptide Y (NPY) in superior mesenteric arteries in portal hypertension
    • DOI 10.1016/j.jhep.2005.08.023, PII S0168827805006069
    • Wiest R, Jurzik L, Moleda L, Froh M, Schnabl B, von Horsten S, et al. Enhanced Y1-receptor-mediated vasoconstrictive action of neuropeptide Y (NPY) in superior mesenteric arteries in portal hypertension. J Hepatol 2006; 44: 512-9. (Pubitemid 43227875)
    • (2006) Journal of Hepatology , vol.44 , Issue.3 , pp. 512-519
    • Wiest, R.1    Jurzik, L.2    Moleda, L.3    Froh, M.4    Schnabl, B.5    Horsten, S.V.6    Scholmerich, J.7    Straub, R.H.8
  • 29
    • 34249724968 scopus 로고    scopus 로고
    • A novel approach for the determination of contractile and calcium responses of the basilar artery employing real-time confocal laser microscopy
    • DOI 10.1016/j.vascn.2007.03.002, PII S1056871907001815
    • Hashimoto T, Ohata H, Nobe K, Sakai Y, Honda K. A novel approach for the determination of contractile and calcium responses of the basilar artery employing real-time confocal laser microscopy. J Pharmacol Toxicol Methods 2007; 56: 79-86. (Pubitemid 46829937)
    • (2007) Journal of Pharmacological and Toxicological Methods , vol.56 , Issue.1 , pp. 79-86
    • Hashimoto, T.1    Ohata, H.2    Nobe, K.3    Sakai, Y.4    Honda, K.5
  • 30
    • 67649998474 scopus 로고    scopus 로고
    • Regulation of the phenylethanolamine N-methyltransferase gene in the adrenal gland of the spontaneous hypertensive rat
    • Nguyen P, Peltsch H, de Wit J, Crispo J, Ubriaco G, Eibl J, et al. Regulation of the phenylethanolamine N-methyltransferase gene in the adrenal gland of the spontaneous hypertensive rat. Neurosci Lett 2009; 461: 280-4.
    • (2009) Neurosci Lett , vol.461 , pp. 280-4
    • Nguyen, P.1    Peltsch, H.2    De Wit, J.3    Crispo, J.4    Ubriaco, G.5    Eibl, J.6
  • 32
    • 0018355751 scopus 로고
    • A comparison of the inhibitory effect of cinnarizine and papaverine on the noradrenaline- and calcium-evoked contraction of isolated rabbit aorta and mesenteric arteries
    • DOI 10.1016/0014-2999(79)90134-1
    • Broekaert A, Godfraind T. A comparison of the inhibitory effect of cinnarizine and papaverine on the noradrenaline- and calcium-evoked contraction of isolated rabbit aorta and mesenteric arteries. Eur J Pharmacol 1979; 53: 281-8. (Pubitemid 9201237)
    • (1979) European Journal of Pharmacology , vol.53 , Issue.3 , pp. 281-288
    • Broekaert, A.1    Godfraind, T.2
  • 33
    • 4544250027 scopus 로고    scopus 로고
    • Receptor-activating peptides for PAR-1 and PAR-2 relax rat gastric artery via multiple mechanisms
    • DOI 10.1016/j.lfs.2004.07.006, PII S0024320504006848
    • Kawabata A, Nakaya Y, Ishiki T, Kubo S, Kuroda R, Sekiguchi F, et al. Receptor-activating peptides for PAR-1 and PAR-2 relax rat gastric artery via multiple mechanisms. Life Sci 2004; 75: 2689-702. (Pubitemid 39215061)
    • (2004) Life Sciences , vol.75 , Issue.22 , pp. 2689-2702
    • Kawabata, A.1    Nakaya, Y.2    Ishiki, T.3    Kubo, S.4    Kuroda, R.5    Sekiguchi, F.6    Kawao, N.7    Nishikawa, H.8    Kawai, K.9
  • 34
    • 33750429908 scopus 로고    scopus 로고
    • Characterization of the mechanisms of action and nitric oxide species involved in the relaxation induced by the ruthenium complex
    • DOI 10.1016/j.niox.2006.04.260, PII S1089860306000589
    • Bonaventura D, Oliveira FS, Lunardi CN, Vercesi JA, da Silva RS, Bendhack LM. Characterization of the mechanisms of action and nitric oxide species involved in the relaxation induced by the ruthenium complex. Nitric Oxide 2006; 15: 387-94. (Pubitemid 44647894)
    • (2006) Nitric Oxide - Biology and Chemistry , vol.15 , Issue.4 , pp. 387-394
    • Bonaventura, D.1    Oliveira, F.S.2    Lunardi, C.N.3    Vercesi, J.A.4    Da Silva, R.S.5    Bendhack, L.M.6
  • 35
    • 0030987260 scopus 로고    scopus 로고
    • Halothane inhibits endothelium-dependent relaxation elicited by acetylcholine in human isolated pulmonary arteries
    • DOI 10.1016/S0014-2999(97)85412-X, PII S0014299997000344
    • Higueras J, Sarria B, Ortiz JL, Cortijo J, Maruenda A, Barbera M, et al. Halothane inhibits endothelium-dependent relaxation elicited by acetylcholine in human isolated pulmonary arteries. Eur J Pharmacol 1997; 326: 175-81. (Pubitemid 27214547)
    • (1997) European Journal of Pharmacology , vol.326 , Issue.2-3 , pp. 175-181
    • Higueras, J.1    Sarria, B.2    Ortiz, J.L.3    Cortijo, J.4    Maruenda, A.5    Barbera, M.6    Morcillo, E.J.7
  • 36
    • 0345368011 scopus 로고    scopus 로고
    • Beta-adrenoceptor-mediated relaxation inhibited by tetrapentylammonium ions in rat mesenteric artery
    • Huang Y, Kwok KH. Beta-adrenoceptor-mediated relaxation inhibited by tetrapentylammonium ions in rat mesenteric artery. Life Sci 1998; 62: PL19-25.
    • (1998) Life Sci , vol.62
    • Huang, Y.1    Kwok, K.H.2
  • 37
    • 18344395686 scopus 로고    scopus 로고
    • Hyperthermia-induced vasoconstriction of the carotid artery and the role of potassium channels
    • DOI 10.1016/j.jstrokecerebrovasdis.2004.12.006, PII S1052305704001843
    • Mustafa S, Thulesius O. Hyperthermia-induced vasoconstriction of the carotid artery and the role of potassium channels. J Stroke Cerebrovasc Dis 2005; 14: 122-6. (Pubitemid 40637604)
    • (2005) Journal of Stroke and Cerebrovascular Diseases , vol.14 , Issue.3 , pp. 122-126
    • Mustafa, S.1    Thulesius, O.2
  • 39
    • 0035943448 scopus 로고    scopus 로고
    • Different role of endothelium/nitric oxide in 17β-estradiol- and progesterone-induced relaxation in rat arteries
    • DOI 10.1016/S0024-3205(01)01235-8, PII S0024320501012358
    • Chan HY, Yao X, Tsang SY, Chan FL, Lau CW, Huang Y. Different role of endothelium/nitric oxide in 17beta-estradiol- and progesteroneinduced relaxation in rat arteries. Life Sci 2001; 69: 1609-17. (Pubitemid 32800640)
    • (2001) Life Sciences , vol.69 , Issue.14 , pp. 1609-1617
    • Chan, H.Y.1    Yao, X.2    Tsang, S.Y.3    Chan, F.L.4    Lau, C.W.5    Huang, Y.6
  • 40
    • 0032799783 scopus 로고    scopus 로고
    • Effects of adenosine receptor agonists on induction of contractions to phenylephrine of guinea-pig aorta mediated via intra- or extracellular calcium
    • DOI 10.1016/S0306-3623(98)00279-1, PII S0306362398002791
    • Ford WR, Broadley KJ. Effects of adenosine receptor agonists on induction of contractions to phenylephrine of guinea-pig aorta mediated via intra- or extracellular calcium. Gen Pharmacol 1999; 33: 143-50. (Pubitemid 29341588)
    • (1999) General Pharmacology , vol.33 , Issue.2 , pp. 143-150
    • Ford, W.R.1    Broadley, K.J.2
  • 41
    • 0035929235 scopus 로고    scopus 로고
    • 2+ influx in rat vascular smooth muscle cells stimulated with 5-hydroxytryptamine
    • DOI 10.1016/S0014-2999(01)01274-2, PII S0014299901012742
    • Hirafuji M, Ebihara T, Kawahara F, Hamaue N, Endo T, Minami M. Inhibition by docosahexaenoic acid of receptor-mediated Ca2+ influx in rat vascular smooth muscle cells stimulated with 5-hydroxytryptamine. Eur J Pharmacol 2001; 427: 195-201. (Pubitemid 32913286)
    • (2001) European Journal of Pharmacology , vol.427 , Issue.3 , pp. 195-201
    • Hirafuji, M.1    Ebihara, T.2    Kawahara, F.3    Hamaue, N.4    Endo, T.5    Minami, M.6
  • 42
    • 0242667857 scopus 로고    scopus 로고
    • Effects of flavonoids on vascular smooth muscle of the isolated rat thoracic aorta
    • DOI 10.1016/j.lfs.2003.06.039
    • Ajay M, Gilani AU, Mustafa MR. Effects of flavonoids on vascular smooth muscle of the isolated rat thoracic aorta. Life Sci 2003; 74: 603-12. (Pubitemid 37410351)
    • (2003) Life Sciences , vol.74 , Issue.5 , pp. 603-612
    • Ajay, M.1    Gilani, A.-U.H.2    Mustafa, M.R.3
  • 43
    • 0021646381 scopus 로고
    • The effects of caffeine on the noradrenaline-sensitive calcium store in rabbit aorta
    • Leijten PA, van Breemen C. The effects of caffeine on the noradrenaline- sensitive calcium store in rabbit aorta. J Physiol 1984; 357: 327-39. (Pubitemid 15175345)
    • (1984) Journal of Physiology , vol.357 , pp. 327-339
    • Leijten, P.A.A.1    Van Breemen, C.2
  • 44
    • 62549107554 scopus 로고    scopus 로고
    • Research on antioxidant effects and estrogenic effect of formononetin from Trifolium pratense (red clover)
    • Mu H, Bai YH, Wang ST, Zhu ZM, Zhang YW. Research on antioxidant effects and estrogenic effect of formononetin from Trifolium pratense (red clover). Phytomedicine 2009; 16: 314-9.
    • (2009) Phytomedicine , vol.16 , pp. 314-9
    • Mu, H.1    Bai, Y.H.2    Wang, S.T.3    Zhu, Z.M.4    Zhang, Y.W.5
  • 45
    • 64949138447 scopus 로고    scopus 로고
    • Synthesis, solubility, lipids-lowering and liver-protection activities of sulfonated formononetin
    • Wang QY, Meng QH, Zhang ZT, Tian ZJ, Liu H. Synthesis, solubility, lipids-lowering and liver-protection activities of sulfonated formononetin. Yao Xue Xue Bao 2009; 44: 386-9.
    • (2009) Yao Xue Xue Bao , vol.44 , pp. 386-9
    • Wang, Q.Y.1    Meng, Q.H.2    Zhang, Z.T.3    Tian, Z.J.4    Liu, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.