Formononetin, an isoflavone, relaxes rat isolated aorta through endothelium-dependent and endothelium-independent pathways

Journal of Nutritional Biochemistry

Volumn 21, Issue 7, 2010, Pages 613-620

  Wu, Jian Hong ^a   Li, Qing ^a,b   Wu, Min Yi ^a   Guo, De Jian ^a   Chen, Huan Le ^a   Chen, Shi Lin ^a,b   Seto, Sai Wang ^c   Au, Alice L S ^c   Poon, Christina C W ^c   Leung, George P H ^d   Lee, Simon M Y ^e   Kwan, Yiu Wa ^c   Chan, Shun Wan ^a,f  

^a State Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation)   (China)

^b INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^c and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

^e University of Macau   (Macao)

^f HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

Formononetin; Nitric oxide; Vasorelaxation

Indexed keywords

BIOCHANIN A; CALCIUM ACTIVATED POTASSIUM CHANNEL; DAIDZEIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FORMONONETIN; GENISTEIN; GLIBENCLAMIDE; GLIBENCLAMIDE PLUS IBERIOTOXIN; IBERIOTOXIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; METHYLENE BLUE; MIFEPRISTONE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; UNCLASSIFIED DRUG; ENZYME INHIBITOR; ISOFLAVONE DERIVATIVE; PHYTOESTROGEN; VASODILATOR AGENT;

ANIMAL TISSUE; AORTA; ARTICLE; CHANNEL GATING; DRUG EFFECT; ENZYME ACTIVITY; NONHUMAN; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE; UPREGULATION; VASOCONSTRICTION; VASODILATATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CARDIOVASCULAR DISEASES; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; GENETICS; IN VITRO STUDY; MALE; METABOLISM; OSMOLARITY; PHYSIOLOGY; PHYTOTHERAPY; SPRAGUE DAWLEY RAT; THORACIC AORTA; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

ASTRAGALUS MONGHOLICUS; RATTUS;

ANIMALS; AORTA, THORACIC; CARDIOVASCULAR DISEASES; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; IN VITRO TECHNIQUES; ISOFLAVONES; MALE; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; OSMOLAR CONCENTRATION; PHYTOESTROGENS; PHYTOTHERAPY; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; UP-REGULATION; VASODILATION; VASODILATOR AGENTS;

EID: 77953812949     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2009.03.010     Document Type: Article

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