Binding of Clostridium difficile toxins to human milk oligosaccharides

Glycobiology

Volumn 21, Issue 9, 2011, Pages 1217-1227

  El Hawiet, Amr ^a   Kitova, Elena N ^a   Kitov, Pavel I ^a   Eugenio, Luiz ^b   Ng, Kenneth K S ^b   Mulvey, George L ^b   Dingle, Tanis C ^b   Szpacenko, Adam ^a   Armstrong, Glen D ^b   Klassen, John S ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Clostridium difficile; cytotoxicity; docking; human milk oligosaccharide; ligand binding; mass spectrometry; toxin

Indexed keywords

AMINE; CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B; DISACCHARIDE; LACTOSAMINE; LACTOSE; OLIGOSACCHARIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; BREAST MILK; CARBOXY TERMINAL SEQUENCE; CLOSTRIDIUM DIFFICILE; CYTOTOXICITY; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; MOLECULAR RECOGNITION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL;

AMINO SUGARS; ANIMALS; BACTERIAL PROTEINS; BACTERIAL TOXINS; BINDING SITES; CARBOHYDRATE SEQUENCE; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; CLOSTRIDIUM DIFFICILE; ENTEROTOXINS; HUMANS; KINETICS; MILK, HUMAN; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; OLIGOSACCHARIDES; PEPTIDE FRAGMENTS; PROTEIN BINDING; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; VERO CELLS;

CLOSTRIDIUM DIFFICILE;

EID: 80051523939     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwr055     Document Type: Article

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