Kinetic and chemical mechanism of malate synthase from mycobacterium tuberculosis

Biochemistry

Volumn 50, Issue 32, 2011, Pages 6879-6887

  Quartararo, Christine E ^a   Blanchard, John S ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL-COA; CARBON-CARBON BOND FORMATION; CHEMICAL MECHANISM; GENERAL BASE; GLYOXYLATE; INITIAL VELOCITIES; KINETIC ANALYSIS; KINETIC DATA; KINETIC ISOTOPE EFFECTS; LINEAR KINETICS; M. TUBERCULOSIS; MALATE SYNTHASE G; METAL-AFFINITY CHROMATOGRAPHY; MYCOBACTERIUM TUBERCULOSIS; N-TERMINALS; PH DEPENDENCE; RATE LIMITING; SEQUENTIAL MECHANISM; SOLVENT ISOTOPE EFFECTS; SOLVENT KINETIC ISOTOPE EFFECTS; SYNTHASES; WILD TYPES;

AFFINITY CHROMATOGRAPHY; CARRIER MOBILITY; CATALYSIS; CHEMICAL BONDS; CITRIC ACID; GENES; ISOTOPES;

KINETICS;

4,4' DITHIODIPYRIDINE; ACETYL COENZYME A; DEUTERIUM OXIDE; GLYOXYLIC ACID; HISTIDINE; MALATE SYNTHASE;

ARTICLE; CATALYSIS; CHEMICAL ANALYSIS; CHEMICAL BOND; CITRIC ACID CYCLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME MECHANISM; GENE; GLCB GENE; IMMOBILIZED METAL AFFINITY CHROMATOGRAPHY; MOLECULAR CLONING; MUTAGENESIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE;

CATALYSIS; CLONING, MOLECULAR; HYDROGEN-ION CONCENTRATION; KINETICS; MALATE SYNTHASE; MUTAGENESIS, SITE-DIRECTED; MYCOBACTERIUM TUBERCULOSIS; POLYMERASE CHAIN REACTION;

MYCOBACTERIUM TUBERCULOSIS;

EID: 80051505605     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi2007299     Document Type: Article

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