Acidic preparations of lysed platelets upregulate proliferative pathways in osteoblast-like cells as demonstrated by genome-wide microarray analysis

Platelets

Volumn 22, Issue 6, 2011, Pages 452-460

  Wahlström, Ola ^a   Linder, Cecilia Halling ^a,b   Ansell, Anna ^a   Kalén, Anders ^a   Söderströ, Mats ^a   Magnusson, Per ^a,b  

^a LINKÖPING UNIVERSITY   (Sweden)

^b Centre of Surgery and Oncology   (Sweden)

Author keywords

Cell proliferation; Gene expression; Hypoxia; Platelets; TGFBR pathway

Indexed keywords

7 DEHYDROCHOLESTEROL REDUCTASE; ACTIN ALPHA2; ACTIN GAMMA2; ALPHA6BETA4 INTEGRIN; ANDROGEN RECEPTOR; BONE MORPHOGENETIC PROTEIN 2; CARBONATE DEHYDRATASE XII; CELL PROTEIN; FARNESYL DIPHOSPHATE FARNESYLTRANSFERASE 1; FIBROBLAST GROWTH FACTOR 2; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; I KAPPA B; INTERLEUKIN 2; INTERLEUKIN 4; LOW DENSITY LIPOPROTEIN RECEPTOR; NOTCH RECEPTOR; PEPTIDYLPROLYL ISOMERASE F; PHOSPHATIDIC ACID PHOSPHATASE TYPE 2B; PHOSPHOLIPASE C BETA4; SOLUTE CARRIER FAMILY 46 MEMBE 3; SONIC HEDGEHOG PROTEIN; TENSIN 1; TRANSCRIPTION FACTOR DP2; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; URIDINE CYTIDINE KINASE 2; VASCULOTROPIN; WNT PROTEIN;

ACIDITY; ADULT; ANGIOGENESIS; ARTICLE; BIOMETRY; CANCER GROWTH; CARCINOGENESIS; CELL DIFFERENTIATION; CELL LYSATE; CELL PROLIFERATION; CHOLESTEROL METABOLISM; CHROMOSOME 1; CONTROLLED STUDY; CYTOSKELETON; DOWN REGULATION; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC IDENTIFICATION; GENETIC REGULATION; HUMAN; HUMAN CELL; INFLAMMATION; LIPID METABOLISM; MALE; MICROARRAY ANALYSIS; NORMAL HUMAN; OPEN READING FRAME; OSSIFICATION; OSTEOBLAST; OSTEOBLAST LIKE CELL; PRIORITY JOURNAL; PROTEIN FOLDING; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STEROIDOGENESIS; THROMBOCYTE; UPREGULATION;

ACIDS; BLOOD PLATELETS; CELL DIFFERENTIATION; CELL EXTRACTS; CELL LINE; CELL PROLIFERATION; FRACTURE HEALING; GENE EXPRESSION PROFILING; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HUMANS; HYDROGEN-ION CONCENTRATION; NEOPLASMS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOBLASTS; OSTEOGENESIS; TRANSFORMING GROWTH FACTOR BETA;

EID: 80051499178     PISSN: 09537104     EISSN: 13691635     Source Type: Journal    
DOI: 10.3109/09537104.2011.565432     Document Type: Article

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