Variation of pH in lysed platelet concentrates influence proliferation and alkaline phosphatase activity in human osteoblast-like cells

Platelets

Volumn 18, Issue 2, 2007, Pages 113-118

  Wahlström, Ola ^a   Linder, Cecilia ^b   Kalén, Anders ^a   Magnusson, Per ^a,b  

^a LINKÖPING UNIVERSITY   (Sweden)

^b LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cell proliferation; Growth factors; Osteoblast stimulation; pH; Platelets

Indexed keywords

ALKALINE PHOSPHATASE; GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; THROMBOCYTE CONCENTRATE; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CELL PH; CELL PROLIFERATION; CONTROLLED STUDY; CYTOLYSIS; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FRACTURE HEALING; HUMAN; HUMAN CELL; IMPLANTATION; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN SECRETION; THROMBOCYTE; WOUND CARE;

ALKALINE PHOSPHATASE; BLOOD PLATELETS; CELL LINE; CELL PROLIFERATION; HUMANS; HYDROGEN-ION CONCENTRATION; OSTEOBLASTS; PLATELET-DERIVED GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA1;

EID: 33947190469     PISSN: 09537104     EISSN: 13691635     Source Type: Journal    
DOI: 10.1080/09537100600800537     Document Type: Article

References (33)

1. Bennett NT, Schultz GS. Growth factors and wound healing: Biochemical properties of growth factors and their receptors. Am J Surg 1993;165:728-737.
2. He C, Hughes MA, Cherry GW, Arnold F. Effects of chronic wound fluid on the bioactivity of PDGF in serum-free medium and its direct effect on fibroblast growth. Wound Rep Reg 1999;7:97-105.
3. Guerne PA, Sublet A, Lotz M. Growth factor responsiveness of human articular chondrocytes: Distinct profiles in primary chondrocytes, subcultured chondrocytes and fibroblasts. J Cell Physiol 1994;158:476-484.
4. Slater M, Patava J, Kingham K, Mason RS. Involvement of platelets in stimulating osteogenic activity. J Orthop Res 1995;13:655-663.
5. Gruber R, Karreth F, Frommlet F, Fischer MB, Watzek G. Platelets are mitogenic for periosteum-derived cells. J Orthop Res 2003;21:941-948.
6. Gruber R, Karreth F, Kandler B, Fuerst G, Rot A, Fischer MB, Watzek G. Platelet-released supernatants increase migration and proliferation, and decrease osteogenic differentiation of bone marrow-derived mesenchymal progenitor cells under in vitro conditions. Platelets 2004;15:29-35.
7. Kawase T, Okuda K, Wolff LF, Yoshie H. Platelet-rich plasma-derived fibrin clot formation stimulates collagen synthesis in periodontal ligament and osteoblastic cells in vitro. J Periodontol 2003;74:858-864.
8. Arpornmaeklong P, Kochel M, Depprich R, Kubler NR, Wurzler KK. Influence of platelet-rich plasma (PRP) on osteogenic differentiation of rat bone marrow stromal cells. An in vitro study. Int J Oral Maxillofac Surg 2004;33:60-70.
9. Doucet C, Ernou I, Zhang Y, Llense JR, Begot L, Holy X, Lataillade JJ. Platelet lysate promote mesenchymal stem cell expansion: A safety substitute for animal serum in cell-based therapy applications. J Cell Physiol 2005;205:228-236.
10. Soffer E, Ouhayoun JP, Dosquet C, Meunier A, Anagnostou F. Effect of platelet lysate on selected bone cell functions. Clin Oral Impl Res 2004;15:581-588.
11. Roldàn JC, Jepsen S, Miller J, Freitag S, Rueger DC, Acil Y, Terheyden H. Bone formation in the presence of platelet-rich plasma vs. bone morphogenic protein-7. Bone 2004;34:80-90.
12. Knighton DR, Fiegel VD, Austin LL, Ciresi KF, Butler EL. Classification and treatment of chronic nonhealing wounds. Successful treatment with autologous platelet-derived wound healing factors (PDWHF). Ann Surg 1986;204:322-330.
13. Knighton DR, Ciresi K, Fiegel VD, Schumerth S, Butler E, Cerra F. Stimulation of repair in chronic, nonhealing, cutaneous ulcers using platelet-derived wound healing formula. Surg Gynecol Obstet 1990;170:56-60.
14. Holloway GA, Steed DL, Demarco MJ, Masumoto T, Moosa HH. Webster MW, Bunt TJ, Polansky M. A randomized controlled multicenter dose response trial of activated platelet supernatant, topical CT-102 in chronic, nonhealing diabetic wounds. Wounds 1993;5:198-206.
15. Steed DL, Goslen JB, Holloway GA, Malone JM, Webster MW. Randomized prospective double-blind trial in healing chronic diabetic foot ulcers. CT-102 activated platelet supernatant, topical versus placebo. Diabetes Care 1992;15:1598-1604.
16. Marx RE, Carlson ER, Eichstedt RM, Schimmelse SR, Strauss JE, Georgeff KR. Platelet-rich plasma. Growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998;85:638-646.
17. Marx RE. Platelet-rich plasma: Evidence to support its use. J Oral Maxillofac Surg 2004;62:489-496.
18. Embil JM, Papp K, Sibbald G, Tousignant J, Smiell JM, Wong B, Lau CY. Recombinant human platelet-derived growth factor-BB(becaplermin) for healing chronic lower extremity diabetic ulcers: An open-label clinical evaluation of efficacy. Wound Rep Reg 2000;8:162-168.
19. Swenson O, Lloyd Claff C. Changes in the hydrogen ion concentration of healing fractures. Proc Soc Exp Biol Med 1946;61:151-154.
20. Edlow DE, Sheldon WH. The pH of inflammatory exudates. Proc Soc Exp Biol Med 1971;137:1328-1332.
21. Chakkalakal DA, Mashoof AA, Novak J, Strates BS, McGuire MH. Mineralization and pH relationship in healing skeletal defects grafted with demineralised bone matrix. J Biomed Mater Res 1994;28:1439-1443.
22. Heuwinkel R, Schneider HM, Störkel S. Der gewebs-pH als stimulans desmaler knochenneubildung. Unfallheilkunde 1980;83:577-585.
23. Newman RJ, Duthie RB, Martin JO. Nuclear magnetic resonance studies of fracture repair. Clin Orthop 1985;198:297-303.
24. Newman RJ, Francis MJ, Duthie RB. Nuclear magnetic resonance studies of experimentally induced delayed fracture union. Clin Orthop 1987;216:253-261.
25. Hollinger J, Wong MEK. The integrated process of hard tissue regeneration with special emphasis on fracture healing. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1996;82:594-606.
26. Liu Y, Kalén A, Risto O, Wahlström O. Fibroblast proliferation due to exposure to a platelet concentrate in vitro is pH dependent. Wound Rep Reg 2002;10:336-340.
27. Harris SA, Enger RJ, Riggs BL, Spelsberg TC. Development and characterization of a conditionally immortalized human fetal osteoblastic cell line. J Bone Miner Res 1995;10:178-186.
28. Spector JA, Mehrara BJ, Greenwald JA, Saadeh PB, Steinbrech DS, Bouletreau PJ, Smith LP, Longaker MT. Osteoblast expression of vascular endothelial growth factor is modulated by the extracellular microenvironment. Am J Physiol Cell Physiol 2000;280:C72-C80.
29. Kaysinger KK, Ramp WK. Extracellular pH modulates the activity of cultured human osteoblasts. J Cell Biochem 1998;68:83-89.
30. Frick KK, Bushinsky DA. Metabolic acidosis stimulates RANKL RNA expression in bone through a cyclooxygenase-dependent mechanism. J Bone Miner Res 2003;18:1317-1325.
31. Centrella M, McCarty TL, Canalis E. Skeletal tissue and transforming growth factor β. FASEB J 1988;2:3066.
32. Rodan GA. Introduction to bone biology. Bone 1992;13:3-6.
33. Stein GS, Lian JB, Stein JL, Van Wijnen AJ. Transcriptional control of osteoblast growth and differentiation. Physiol Rev 1996;76:593-629.