The hydrophobic amino acids in putative helix 8 in carboxy-terminus of histamine H3 receptor are involved in receptor-G-protein coupling

Cellular Signalling

Volumn 23, Issue 11, 2011, Pages 1843-1849

  Kuramasu, Atsuo ^a   Sukegawa, Jun ^a   Sato, Takeya ^a   Sakurai, Eiko ^a   Watanabe, Takehiko ^a   Yanagisawa, Teruyuki ^a   Yanai, Kazuhiko ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

G protein coupled receptor; Helix 8; Histamine H3 receptor; Signaling

Indexed keywords

ALANINE; AMINO ACID; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; HISTAMINE H3 RECEPTOR; LEUCINE; MITOGEN ACTIVATED PROTEIN KINASE; PHENYLALANINE; THIOPERAMIDE;

ALPHA HELIX; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELL STRAIN HEK293; CELL SURFACE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; HUMAN; HUMAN CELL; HYDROPHOBICITY; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN EXPRESSION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; AMINO ACIDS; CELL MEMBRANE; CYCLIC AMP; FLOW CYTOMETRY; GTP-BINDING PROTEINS; HEK293 CELLS; HISTAMINE; HISTAMINE AGONISTS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PIPERIDINES; PLASMIDS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, HISTAMINE H3; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 80051471195     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2011.06.021     Document Type: Article

References (26)

1. Haas H.L., Sergeeva O.A., Selbach O. Physiol. Rev. 2008, 88:1183-1241.
2. Leurs R., Bakker R.A., Timmerman H., de Esch I.J. Nat. Rev. Drug Discov. 2005, 4:107-120.
3. Palczewski K., Kumasaka T., Hori T., Behnke C.A., Motoshima H., Fox B.A., Le Trong I., Teller D.C., Okada T., Stenkamp R.E., Yamamoto M., Miyano M. Science 2000, 289:739-745.
4. Cherezov V., Rosenbaum D.M., Hanson M.A., Rasmussen S.G., Thian F.S., Kobilka T.S., Choi H.J., Kuhn P., Weis W.I., Kobilka B.K., Stevens R.C. Science 2007, 318:1258-1265.
5. Jaakola V.P., Griffith M.T., Hanson M.A., Cherezov V., Chien E.Y., Lane J.R., Ijzerman A.P., Stevens R.C. Science 2008, 322:1211-1217.
6. Okuno T., Ago H., Terawaki K., Miyano M., Shimizu T., Yokomizo T. J. Biol. Chem. 2003, 278:41500-41509.
7. Verzijl D., Pardo L., van Dijk M., Gruijthuijsen Y.K., Jongejan A., Timmerman H., Nicholas J., Schwarz M., Murphy P.M., Leurs R., Smit M.J. J. Biol. Chem. 2006, 281:35327-35335.
8. Zhong M., Navratil A.M., Clay C., Sanborn B.M. Biochemistry 2004, 43:3490-3498.
9. Yasuda D., Okuno T., Yokomizo T., Hori T., Hirota N., Hashidate T., Miyano M., Shimizu T., Nakamura M. FASEB J. 2009, 23:1470-1481.
10. Leclerc P.C., Auger-Messier M., Lanctot P.M., Escher E., Leduc R., Guillemette G. Endocrinology 2002, 143:4702-4710.
11. Thielen A., Oueslati M., Hermosilla R., Krause G., Oksche A., Rosenthal W., Schülein R. FEBS Lett. 2005, 579:5227-5235.
12. Delos Santos N.M., Gardner L.A., White S.W., Bahouth S.W. J. Biol. Chem. 2006, 281:12896-12907.
13. Tetsuka M., Saito Y., Imai K., Doi H., Maruyama K. Endocrinology 2004, 145:3712-3723.
14. Uveges A.J., Kowal D., Zhang Y., Spangler T.B., Dunlop J., Semus S., Jones P.G. J. Pharmacol. Exp. Ther. 2002, 301:451-458.
15. Bakker R.A., Lozada A.F., van Marle A., Shenton F.C., Drutel G., Karlstedt K., Hoffmann M., Lintunen M., Yamamoto Y., van Rijn R.M., Chazot P.L., Panula P., Leurs R. Mol. Pharmacol. 2006, 69:1194-1206.
16. Maeda K., Haraguchi M., Kuramasu A., Sato T., Ariake K., Sakagami H., Kondo H., Yanai K., Fukunaga K., Yanagisawa T., Sukegawa J. Biochem. Biophys. Res. Commun. 2008, 369:603-608.
17. Ballesteros J.A., Weinstein H.W. Methods Neurosci. 1995, 25:366-428.
18. Xu A.J., Kuramasu A., Maeda K., Kinoshita K., Takayanagi S., Fukushima Y., Watanabe T., Yanagisawa T., Sukegawa J., Yanai K. J. Neurochem. 2008, 107:208-217.
19. Esbenshade T.A., Krueger K.M., Miller T.R., Kang C.H., Denny L.I., Witte D.G., Yao B.B., Fox G.B., Faghih R., Bennani Y.L., Williams M., Hancock A.A. J. Pharmacol. Exp. Ther. 2003, 305:887-896.
20. Krueger K.M., Witte D.G., Ireland-Denny L., Miller T.R., Baranowski J.L., Buckner S., Milicic I., Esbenshade T.A., Hancock A.A. J. Pharmacol. Exp. Ther. 2005, 314:271-281.
21. Drutel G., Peitsaro N., Karlstedt K., Wieland K., Smit M.J., Timmerman H., Panula P., Leurs R. Mol. Pharmacol. 2001, 59:1-8.
22. Marinissen M.J., Gutkind J.S. Trends Pharmacol. Sci. 2001, 22:368-376.
23. Prioleau C., Visiers I., Ebersole B.J., Weinstein H., Sealfon S.C. J. Biol. Chem. 2002, 277:36577-36584.
24. Dupré D.J., Robitaille M., Richer M., Ethier N., Mamarbachi A.M., Hébert T.E. J. Biol. Chem. 2007, 282:13703-13715.
25. Conn P.J., Christopoulos A., Lindsley C.W. Nat. Rev. Drug Discov. 2009, 8:41-54.
26. Andrews G., Jones C., Wreggett K.A. Mol. Pharmacol. 2008, 73:855-867.