The hydrophobic amino acid residues in the membrane-proximal C tail of the G protein-coupled vasopressin V2 receptor are necessary for transport-competent receptor folding

FEBS Letters

Volumn 579, Issue 23, 2005, Pages 5227-5235

  Thielen, Anja ^a   Oueslati, Morad ^a   Hermosilla, Ricardo ^b   Krause, Gerd ^a   Oksche, Alexander ^b   Rosenthal, Walter ^a,b   Schülein, Ralf ^a  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

C tail; Endoplasmic reticulum; G protein coupled receptor; Quality control system; Receptor trafficking; Transport motif; Vasopressin V2 receptor

Indexed keywords

G PROTEIN COUPLED RECEPTOR KINASE 2;

AMINO ACID ANALYSIS; ARTICLE; CONTROLLED STUDY; GLYCOSYLATION; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; MEMBRANE TRANSPORT; PRIORITY JOURNAL; PROTEIN FOLDING; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; ARGININE VASOPRESSIN; BIOLOGICAL TRANSPORT; CELL LINE; HUMANS; HYDROPHOBICITY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN FOLDING; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, VASOPRESSIN; RECOMBINANT FUSION PROTEINS;

EID: 24944480770     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.08.043     Document Type: Article

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