Thioredoxin interacting protein is a novel mediator of retinal inflammation and neurotoxicity

British Journal of Pharmacology

Volumn 164, Issue 1, 2011, Pages 170-180

  Al Gayyar, Mohammed M H ^a,b,c,d   Abdelsaid, Mohammed A ^a,b,c   Matragoon, Suraporn ^a,b,c   Pillai, Bindu A ^a,b,c   El Remessy, Azza B ^a,b,c  

^a UNIVERSITY OF GEORGIA   (United States)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d MANSOURA UNIVERSITY   (Egypt)

Author keywords

apoptosis; neurodegeneration; neuroprotection; NMDA; peroxynitrite; retina; retinal ganglion cells; Thioredoxin; TXNIP; verapamil

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; APOPTOSIS SIGNAL REGULATING KINASE 1; CALCIUM CHANNEL BLOCKING AGENT; CASPASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; N METHYL DEXTRO ASPARTIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; STRESS ACTIVATED PROTEIN KINASE; THIOREDOXIN INTERACTING PROTEIN; TUMOR NECROSIS FACTOR ALPHA; VERAPAMIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG TARGETING; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME RELEASE; GLIA CELL; MEDIATOR RELEASE; NERVE CELL; NEUROPROTECTION; NEUROTOXICITY; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA DEGENERATION; RETINITIS; SLOT BLOT HYBRIDIZATION; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; CARRIER PROTEINS; CASPASE 3; EYE DISEASES; INFLAMMATION; INTERLEUKIN-1BETA; MALE; MAP KINASE KINASE 4; MAP KINASE KINASE KINASE 5; NEUROGLIA; NEUROPROTECTIVE AGENTS; NF-KAPPA B; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, SPRAGUE-DAWLEY; RETINA; RETINAL GANGLION CELLS; THIOREDOXINS; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE; UP-REGULATION; VERAPAMIL;

EID: 79961243931     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01336.x     Document Type: Article

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