Increased nuclear factor-κB p65 immunoreactivity following retinal ischemia and reperfusion injury in mice

Journal of Neuroscience Research

Volumn 72, Issue 1, 2003, Pages 125-131

  Chen, Yue guo ^a   Zhang, Cheng ^a   Chiang, Samuel K S ^a   Wu, Tinghuai ^a   Tso, Mark O M ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Immunohistochemistry; Ischemia and reperfusion; Mice; NF B; Retina

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CELL SURVIVAL; CONTROLLED STUDY; EDEMA; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INTRAOCULAR PRESSURE; MALE; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; REPERFUSION INJURY; RETINA DEGENERATION; RETINA ISCHEMIA;

ANIMALS; EYE; IMMUNOCHEMISTRY; ISCHEMIA; MALE; MICE; MICE, INBRED C57BL; NF-KAPPA B; REPERFUSION INJURY; RETINA;

EID: 0037379883     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10548     Document Type: Article

References (32)

1. Acarin L, Gonzalez B, Castellano B. 1998. Stat3 and NF-κB glial expression after excitotoxic damage to the postnatal brain. Neuroreport 9:2869-2873.
2. Aronowski J, Strong R, Kang HS, Grotta JC. 2000. Selective up-regulation of IκB-alpha in ischemic penumbra following focal cerebral ischemia. Neuroreport 11:1529-1533.
3. Botchkina GI, Geimonen E, Bilof ML, Villarreal O, Tracey KJ. 1999. Loss of NF-κB activity during cerebral ischemia and TNF cytotoxicity. Mol Med 5:372-381.
4. Choi JS, Kim-Yoon S, Joo CK. 1998. NF-κB activation following optic nerve transection. Korean J Ophthalmol 12:19-24.
5. Clemens JA, Stephenson DT, Smalstig EB, Dixon EP, Little SP. 1997. Global ischemia activates NF-κB in forebrain neurons of rats. Stroke 28:1073-1081.
6. Clemens JA, Stephenson DT, Yin T, Smalstig EB, Panetta JA, Little SP. 1998. Drug-induced neuroprotection from global ischemia is associated with prevention of persistent but not transient activation of NF-κB in rats. Stroke 29:677-682.
7. Dixon EP, Stephenson DT, Clemens JA, Little SP. 1997. Bcl-Xshort is elevated following severe global ischemia in rat brains. Brain Res 776:222-229.
8. Gabriel C, Justicia C, Camins A, Planas AM. 1999. Activation of NF-κB in the rat brain after transient focal ischemia. Brain Res Mol Brain Res 65:61-69.
9. Grilli M, Pizzi M, Memo M, Spano PF. 1996. Neuroprotection by aspirin and sodium salicylate through blockade of NF-κB activation. Science 274:1383-1385.
10. Guerrini L, Blasi F, Denis-Donini S. 1995. Synaptic activation of NF-κB by glumtamate in cerebellar granule neurons in vitro. Proc Natl Acad Sci USA 92:9077-9081.
11. Guerrini L, Molteni A, Wirth T, Kistler B, Blasi F. 1997. Glutamate-dependent activation of NF-κB during mouse cerebellum development. J Neurosci 17:6057-6063.
12. Harada C, Harada T, Slusher BS, Yoshida K, Matsuda H, Wada K. 2000. N-acetylated-α-linked-acidic dipeptidase inhibitor has a neuroprotective effect on mouse retinal ganglion cells after pressure-induced ischemia. Neurosci Lett 286:134-136.
13. Irving EA, Hadingham SJ, Roberts J, Gibbons M, Chabot-Fletcher M, Roshak A, Parsons AA. 2000. Decreased NF-κB binding activity following permanent focal cerebral ischemia in the rat. Neurosci Lett 288:45-48.
14. Kaltschmidt C, Kaltschmidt B, Neumann H, Wekerle H, Baeuerle PA. 1994. Constitutive NF-κB activity in neurons. Mol Cell Biol 14:3981-3992.
15. Katai N, Yoshimura N. 1999. Apoptotic retinal neuronal death by ischemia-reperfusion is executed by two distinct caspase family proteases. Invest Ophthalmol Vis Sci 40:2697-2705.
16. Lipton P. 1999. Ischemic cell death in brain neurons. Physiol Rev 79:1431-1568.
17. Matsuoka Y, Kitamura Y, Okazaki M, Terai K, Taniguchi T. 1999. Kainic acid-induced activation of nuclear factor κB in rat hippocampus. Exp Brain Res 124:215-222.
18. Mattson MP, Camandola S. 2001. NF-κB in neuronal plasticity and neurodegenerative disorders. J Clin Invest 107:247-254.
19. Mattson MP, Goodman Y, Luo H, Fu W, Furukawa K. 1997. Activation of NF-κB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of Mn-SOD and suppression of peroxynitrite production and protein tyrosine nitration. J Neurosci Res 49:681-697.
20. Mattson MP, Culmsee C, Yu ZF. 2000. Apoptotic and antiapoptotic mechanism in stroke. Cell Tissue Res 301:173-187.
21. Nanri K, Montecot C, Springhetti V, Seylaz J, Pinard E. 1998. The selective inhibitor of neuronal nitric oxide synthase, 7-nitroindazole, reduces the delayed neuronal damage due to forebrain ischemia in rats. Stroke 29:1248-1254.
22. Perez-Otano I, Mcmillian MK, Chen J, Bing G, Hong JS, Pennypacker KR. 1996. Induction of NF-κB-like transcription factors in brain areas susceptible to kainate toxicity. Glia 16:306-315.
23. Qin ZH, Chen RW, Wang Y, Nakai M, Chuang DM, Chase TN. 1999. Nuclear factor κB nuclear translocation upregulates c-myc and p53 expression during NMDA-receptor-mediated apoptosis in rat striatum. J Neurosci 19:4023-4033.
24. Schneider A, Martin-Villalba A, Weih F, Vogel J, Schwaninger TW. 1999. NF-κB is activated and promotes cell death in focal cerebral ischemia. Nat Med 5:554-559.
25. Sen R, Baltimore D. 1986. Inducibility of kappa immunoglobulin enhancer-binding protein Nf-κB by a posttranslational mechanism. Cell 47:921-928.
26. Tamatani M, Che YH, Matsuzaki H, Ogawa S, Okado H, Miyake S, Mizuno T, Tohyama M. 1999. Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NF-κB activation in primary hippocampal neurons. J Biol Chem 274:8531-8538.
27. Wilde GJC, Pringle AK, Sundstrom LE, Mann DA, Iannotti F. 2000. Attenuation and augmentation of ischemia-related neuronal death by TNF-α in vitro. Eur J Neurosci 12:3863-3870.
28. Wu T, Chen Y, Chiang SK, Tso MOM. 2002. NF-kappaB activation in light-induced retinal degeneration in a mouse model. Invest Ophthalmol Vis Sci 43:2834-2840.
29. Xie QW, Kashiwabara Y, Nathan C. 1994. Role of transcription factor NF-κB/Rel in induction of nitric oxide synthase. J Biol Chem 269:4705-4708.
30. Yu ZF, Zhou D, Bruce-Keller AJ, Kindy MS, Mattson MP. 1999. Lack of the p50 subunit of NF-κB increases the vulnerability of hippocampal neurons to excitotoxic injury. J Neurosci 19:8856-8865.
31. Zabel U, Henkel T, Silva MS, Baeuerle PA. 1993. Nuclear uptake control of NF-κB by MAD-3, and I kappa B protein present in the nucleus. EMBO J 12:201-211.
32. Zhang S, Tobaru T, Zivin JA, Shackelford DA. 1998. Activation of NF-κB in the rabbit spinal cord following ischemia and reperfusion. Brain Res Mol Brain Res 63:121-132.