Edaravone, a free radical scavenger, protects against retinal damage in vitro and in vivo

Journal of Pharmacology and Experimental Therapeutics

Volumn 329, Issue 2, 2009, Pages 687-698

  Inokuchi, Yuta ^a,b   Imai, Shunsuke ^a   Nakajima, Yoshimi ^a   Shimazawa, Masamitsu ^a,b   Aihara, Makoto ^c   Araie, Makoto ^c   Hara, Hideaki ^a,b  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b RIKEN   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; 8 HYDROXYDEOXYGUANOSINE; GLUCOSE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NORPHENAZONE; OXYGEN; SODIUM; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE; TETRAZOLIUM; CYAN FLUORESCENT PROTEIN; DRUG DERIVATIVE; FREE RADICAL; GREEN FLUORESCENT PROTEIN; N METHYLASPARTIC ACID; PHENAZONE; PHENYLMETHYLPYRAZOLONE; SCAVENGER; THY 1 ANTIGEN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSAY; CELL DEATH; CELL LOSS; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; ENZYME PHOSPHORYLATION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR PROBE; MOUSE; NEUROPROTECTION; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADICAL REACTION; RAT; RETINA CELL; RETINA GANGLION CELL; RETINA INJURY; ANIMAL; CELL LINE; CELL SURVIVAL; CULTURE MEDIUM; DISEASE MODEL; DOSE RESPONSE; GENETICS; METABOLISM; PATHOLOGY; RETINA DISEASE; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, THY-1; ANTIPYRINE; CELL LINE; CELL SURVIVAL; CULTURE MEDIA; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICAL SCAVENGERS; FREE RADICALS; GREEN FLUORESCENT PROTEINS; MALE; MICE; MICE, TRANSGENIC; N-METHYLASPARTATE; OXIDATIVE STRESS; RATS; RETINAL DISEASES; RETINAL GANGLION CELLS;

EID: 65649147852     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.148676     Document Type: Article

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