-
1
-
-
0344936018
-
Oxygenation of squamous cell carcinoma of the head and neck: Comparison of primary tumors, neck node metastases, and normal tissue
-
DOI 10.1016/S0360-3016(98)00182-5, PII S0360301698001825
-
Becker A, Hänsgen G, Bloching M, et al: Oxygenation of squamous cell carcinoma of the head and neck: comparison of primary tumors, neck node metastases, and normal tissue. Int J Radiat Oncol Biol Phys 42: 35-41, 1998. (Pubitemid 28435593)
-
(1998)
International Journal of Radiation Oncology Biology Physics
, vol.42
, Issue.1
, pp. 35-41
-
-
Becker, A.1
Hansgen, G.2
Blocking, M.3
Weigel, C.4
Lautenschlager, C.5
Dunst, J.6
-
2
-
-
0035313697
-
HIF-1 and mechanisms of hypoxia sensing
-
Semenza GL: HIF-1 and mechanisms of hypoxia sensing. Curr Opini Cell Biol 13: 167-171, 2001.
-
(2001)
Curr Opini Cell Biol
, vol.13
, pp. 167-171
-
-
Semenza, G.L.1
-
3
-
-
10644234769
-
The role of hypoxia-inducible factors in tumor progression
-
Vaupel P: The role of hypoxia-inducible factors in tumor progression. Oncologist (suppl 5): 10-17, 2004.
-
(2004)
Oncologist
, Issue.SUPPL. 5
, pp. 10-17
-
-
Vaupel, P.1
-
4
-
-
40949142209
-
The role of hypoxia-inducible factors in tumorigenesis
-
Rankin ER and Giaccia AJ: The role of hypoxia-inducible factors in tumorigenesis. Cell Death Differ 15: 678-685, 2008.
-
(2008)
Cell Death Differ
, vol.15
, pp. 678-685
-
-
Rankin, E.R.1
Giaccia, A.J.2
-
5
-
-
0030937718
-
Activation of hypoxia-inducible factor-1; Definition of regulatory domains within the alpha subunit
-
DOI 10.1074/jbc.272.17.11205
-
Pugh CW, ORouke JF, Nagao M, et al: Activation of hypoxia-inducible factor-1: definition of regulatory domains within the alpha subunit. J Biol Chem 272: 11205-11214, 1997. (Pubitemid 27184117)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.17
, pp. 11205-11214
-
-
Pugh, C.W.1
O'Rourke, J.F.2
Nagao, M.3
Gleadle, J.M.4
Ratcliffe, P.J.5
-
7
-
-
0004154783
-
-
Richard R. Smith, Inc., New York
-
Warburg O: The Metabolism of Tumors. Richard R. Smith, Inc., New York, 1930, pp129-169.
-
(1930)
The Metabolism of Tumors
, pp. 129-169
-
-
Warburg, O.1
-
8
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J: Tumor angiogenesis: therapeutic implications. N Engl J Med 285: 1182-1186, 1971.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
9
-
-
47749096350
-
Hypoxic regulation of mRNA expression
-
Gardner LB and Corn PG: Hypoxic regulation of mRNA expression. Cell Cycle 7: 1916-1924, 2008.
-
(2008)
Cell Cycle
, vol.7
, pp. 1916-1924
-
-
Gardner, L.B.1
Corn, P.G.2
-
10
-
-
34547107592
-
Hypoxia-driven selection of metastatic phenotype
-
Sullivan R and Graham CH: Hypoxia-driven selection of metastatic phenotype. Cancer Metastasis Rev 26: 319-331, 2007.
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 319-331
-
-
Sullivan, R.1
Graham, C.H.2
-
11
-
-
34547125574
-
Hypoxia, gene expression and metastasis
-
Chan DA and Giaccia AJ: Hypoxia, gene expression and metastasis. Cancer Metastasis Rev 26: 333-339, 2007.
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 333-339
-
-
Chan, D.A.1
Giaccia, A.J.2
-
12
-
-
0034037286
-
Microenvironment-induced metastasis
-
Rofstad EK: Microenvironment-induced metastasis. Int J Radiat Biol 76: 589-605, 2000.
-
(2000)
Int J Radiat Biol
, vol.76
, pp. 589-605
-
-
Rofstad, E.K.1
-
13
-
-
0037279517
-
The hypoxic tumour microenvironment and metastatic progression
-
DOI 10.1023/A:1022939318102
-
Subarsky P and Hill RP: The hypoxic tumor microenvironment and metastatic progression. Clin Exp Metastasis 20: 237-250, 2003. (Pubitemid 36513228)
-
(2003)
Clinical and Experimental Metastasis
, vol.20
, Issue.3
, pp. 237-250
-
-
Subarsky, P.1
Hill, R.P.2
-
14
-
-
3142631966
-
The human tumor microenvironment: Invasive (needle) measurement of oxygen and interstitial fluid pressure
-
DOI 10.1016/j.semradonc.2004.04.006, PII S1053429604000578
-
Mirosevic M, Fyles A, Hedley D, et al: The human tumor microenvironment: invasive (needle) measurement of oxygen and interstitial pressure. Semin Radiat Oncol 14: 249-258, 2004. (Pubitemid 38903229)
-
(2004)
Seminars in Radiation Oncology
, vol.14
, Issue.3
, pp. 249-258
-
-
Milosevic, M.1
Fyles, A.2
Hedley, D.3
Hill, R.4
-
15
-
-
34250166555
-
Differential risk assessments from five hypoxia specific assays: The basis for biologically adapted individualized radiotherapy in advanced head and neck cancer patients
-
DOI 10.1016/j.radonc.2007.04.021, PII S016781400700179X, Highlights from the 10th International ESTRO-Wolfsberg Meeting on Molecular Radiation Biology/Oncology 2007
-
Nordsmark M, Ericksen JG, Gevski V, et al: Differential risk assessment from five hypoxia specific assays; the basis for biologically adapted indivisualized radiotherapy in advanced head and neck cancer. Radiother Oncol 83: 389-397, 2007. (Pubitemid 46907981)
-
(2007)
Radiotherapy and Oncology
, vol.83
, Issue.3
, pp. 389-397
-
-
Nordsmark, M.1
Eriksen, J.G.2
Gebski, V.3
Alsner, J.4
Horsman, M.R.5
Overgaard, J.6
-
16
-
-
0035893396
-
Acute (cyclic) hypoxia enhances spontaneous metastasis of KHT murine tumors
-
Cairns RA, Kalliomaki T and Hill RP: Acute (cyclic) hypoxia enhances spontaneous metastasis of KHT murine tumors. Cancer Res 61: 8903-8908, 2001. (Pubitemid 34013907)
-
(2001)
Cancer Research
, vol.61
, Issue.24
, pp. 8903-8908
-
-
Cairns, R.A.1
Kalliomaki, T.2
Hill, R.P.3
-
17
-
-
84995290213
-
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumors
-
Graeber TG, Osmanian C, Jacks T, et al: Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumors. Nature 440: 1222-1226, 2006.
-
(2006)
Nature
, vol.440
, pp. 1222-1226
-
-
Graeber, T.G.1
Osmanian, C.2
Jacks, T.3
-
18
-
-
33646365644
-
Lysyl oxidase is essential for hypoxia-induced metastasis
-
Erler JT, Bennewith KL, Nicholau M, et al: Lysyl oxidase is essential for hypoxia-induced metastasis. Nature 440: 1222-1226 2006.
-
(2006)
Nature
, vol.440
, pp. 1222-1226
-
-
Erler, J.T.1
Bennewith, K.L.2
Nicholau, M.3
-
19
-
-
0037374289
-
Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1
-
Krishnamachary B, Berg-Dixon S, Kelly B, et al: Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1. Cancer Res 63: 1138-1143, 2003. (Pubitemid 36278449)
-
(2003)
Cancer Research
, vol.63
, Issue.5
, pp. 1138-1143
-
-
Krishnamachary, B.1
Berg-Dixon, S.2
Kelly, B.3
Agani, F.4
Feldser, D.5
Ferreira, G.6
Iyer, N.7
LaRusch, J.8
Pak, B.9
Taghavi, P.10
Semenza, G.L.11
-
20
-
-
0031993988
-
Tumoural vascularity as a prognostic factor in cancer patients: The evidence continues to grow
-
Weidner N: Tumoural vascularity as a prognostic factor in cancer patients: the evidence continues to grow. J Pathol 184: 119-122, 1998.
-
(1998)
J Pathol
, vol.184
, pp. 119-122
-
-
Weidner, N.1
-
21
-
-
0031688165
-
Tumour hypoxia and vascular density as predictors of metastasis in squamous cell carcinoma of the uterine cervix
-
Sundfor K, Lyng H and Rofstad EK: Tumoral hypoxia and vascular density as predictors of metastasis in squamous cell carcinoma of the uterine cervix. Br J Cancer 78: 822-827, 1998. (Pubitemid 28418321)
-
(1998)
British Journal of Cancer
, vol.78
, Issue.6
, pp. 822-827
-
-
Sundfor, K.1
Lyng, H.2
Rofstad, E.K.3
-
23
-
-
0032774194
-
Hypoxia-induced metastasis of human melanoma cells: Involvement of vascular endothelial growth factor-mediated angiogenesis
-
DOI 10.1038/sj.bjc.6690586
-
Rofstad EK and Danielsen T: Hypoxia-induced metastasis of human melanoma cells: involvement of vascular endothelial growth factor-mediated angiogenesis. Br J Cancer 80: 1697-1707, 1999. (Pubitemid 29389621)
-
(1999)
British Journal of Cancer
, vol.80
, Issue.11
, pp. 1697-1707
-
-
Rofstad, E.K.1
Danielsen, T.2
-
24
-
-
84966192535
-
The histological structure of some human lung cancers and the possible implications for radiotherapy
-
Thomlinson RH and Gray LH: The histological structure of some human lung cancers and the possible implications for radiotherapy. Br J Cancer 9: 539-549, 1955.
-
(1955)
Br J Cancer
, vol.9
, pp. 539-549
-
-
Thomlinson, R.H.1
Gray, L.H.2
-
25
-
-
33750940371
-
The role of cadherin/catenin complex in malignant melanoma
-
Bonitsis N, baitstatou A, Karantima S, et al: The role of cadherin/catenin complex in malignant melanoma. Exp Oncol 28: 187-193, 2006. (Pubitemid 44735907)
-
(2006)
Experimental Oncology
, vol.28
, Issue.3
, pp. 187-193
-
-
Bonitsis, N.1
Batistatou, A.2
Karantima, S.3
Charalabopoulos, K.4
-
26
-
-
12544252343
-
β-Catenin: A pivotal between cell adhesion and Wnt signaling
-
Bienz M: β-Catenin: a pivotal between cell adhesion and Wnt signaling. Curr Biol 15: R64-R67, 2005.
-
(2005)
Curr Biol
, vol.15
-
-
Bienz, M.1
-
27
-
-
33646707041
-
Effect of antisense hypoxia-inducible factor 1 alpha on progression, metastasis, and chemosensitivity of pancreas cancer
-
Chang Q, Qin R, Huang T, et al: Effect of antisense hypoxia-inducible factor 1 alpha on progression, metastasis, and chemosensitivity of pancreas cancer. Pancreas 32: 297-305, 2006.
-
(2006)
Pancreas
, vol.32
, pp. 297-305
-
-
Chang, Q.1
Qin, R.2
Huang, T.3
-
28
-
-
2542588628
-
Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates
-
Koike t, Kimura N, Miyazaki K, et al: Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates. Proc Natl Acad Sci USA 101: 8132-8137, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 8132-8137
-
-
Koike, T.1
Kimura, N.2
Miyazaki, K.3
-
29
-
-
0033621847
-
Beta1 Integrins play an essential role in adhesion and invasion of pancreatic carcinoma cells
-
DOI 10.1097/00006676-200003000-00004
-
Arao S, Matsumoto A, Otsuki MB, et al: Beta 1 integrins play an essential role in adhesion and invasion of pancreatic carcinoma cells. Pancreas 20: 129-137, 2000. (Pubitemid 30123863)
-
(2000)
Pancreas
, vol.20
, Issue.2
, pp. 129-137
-
-
Arao, S.1
Masumoto, A.2
Otsuki, M.3
-
30
-
-
0033521864
-
Hypoxia-mediated stimulation of carcinoma cell invasiveness via upregulation of urokinase receptor expression
-
DOI 10.1002/(SICI)1097-0215(19990209)80:4<617::AID-IJC22>3.0.CO;2-C
-
Graham CH, Forsdike J, Fitzgerald CJ, et al: Hypoxia-mediated stimulation of carcinoma cell invasiveness via upregulation of urokinase receptor expression. Int J Cancer 80: 617-623, 1999. (Pubitemid 29047530)
-
(1999)
International Journal of Cancer
, vol.80
, Issue.4
, pp. 617-623
-
-
Graham, C.H.1
Forsdike, J.2
Fitzgerald, C.J.3
Macdonald-Goodfellow, S.4
-
31
-
-
27744567839
-
Hypoxia level and matrix metalloproteinase-2 and -9 activity in Lewis lung carcinoma correlation with metastasis
-
Osisnsky SP, Ganusevich H, Bubonovskaya LN, et al: Hypoxia level and matrix metalloproteinase-2 and -9 activity in Lewis lung carcinoma correlation with metastasis. Exp Oncol 27: 202-205, 2005.
-
(2005)
Exp Oncol
, vol.27
, pp. 202-205
-
-
Osisnsky, S.P.1
Ganusevich, H.2
Bubonovskaya, L.N.3
-
32
-
-
0037086083
-
Hypoxia promotes lymph node metastasis in human melanoma xenografts by upregulating the urokinase-type plasminogen activator receptor
-
Rofstad EK, Rasmussen H, Galappathi K, et al: Hypoxia promotes lymph node metastasis in human melanoma xenografts by upregulating the urokinase-type plasminogen activator receptor. Cancer Res 62: 1847-1853, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 1847-1853
-
-
Rofstad, E.K.1
Rasmussen, H.2
Galappathi, K.3
-
33
-
-
33751280734
-
Lysyl oxidase mediates hypoxic control of metastasis
-
DOI 10.1158/0008-5472.CAN-06-3197
-
Erler JT and Giaccia AJ: Lysyl oxidase mediates hypoxic control of metastasis. Cancer Res 66: 10238-10241, 2006. (Pubitemid 44799737)
-
(2006)
Cancer Research
, vol.66
, Issue.21
, pp. 10238-10241
-
-
Erler, J.T.1
Giaccia, A.J.2
-
34
-
-
26944478634
-
Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a Ras-activated enhancer
-
DOI 10.1038/sj.onc.1208800, PII 1208800
-
Zhu Y, Denhardt DT, Gao H, et al: Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a Ras-activated enhancer. Oncogene 24: 6555-6563, 2005. (Pubitemid 41486638)
-
(2005)
Oncogene
, vol.24
, Issue.43
, pp. 6555-6563
-
-
Zhu, Y.1
Denhardt, D.T.2
Cao, H.3
Sutphin, P.D.4
Koong, A.C.5
Giaccia, A.J.6
Le, Q.-T.7
-
35
-
-
6344258588
-
The role of osteopontin in tumor metastasis
-
Wai PY and Kuo PC: The role of osteopontin in tumor metastasis. J Surg Res 121: 228-241, 2004.
-
(2004)
J Surg Res
, vol.121
, pp. 228-241
-
-
Wai, P.Y.1
Kuo, P.C.2
-
36
-
-
0030926461
-
Osteopontin induces increased invasiveness and plasminogen activator expression of human mammary carcinomas
-
Tuck AB, Arsenault DM, O'Malley PP, et al: Osteopontin induces increased invasiveness and plasminogen activator expression of human mammary carcinomas. Arch Pathol Lab Med 121: 578-584, 1997.
-
(1997)
Arch Pathol Lab Med
, vol.121
, pp. 578-584
-
-
Tuck, A.B.1
Arsenault, D.M.2
O'Malley, P.P.3
-
37
-
-
0032784057
-
Osteopontin: Possible role in prostate cancer progression
-
Thalman GN, Sikes RA, Devoll RE, et al: Osteopontin: possible role in prostate cancer progression. Clin Cancer Res 5: 2271-2277, 1999. (Pubitemid 29399287)
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.8
, pp. 2271-2277
-
-
Thalmann, G.N.1
Sikes, R.A.2
Devoll, R.E.3
Kiefer, J.A.4
Markwalder, R.5
Klima, I.6
Farach-Carson, C.M.7
Studer, U.E.8
Chung, L.W.K.9
-
38
-
-
0037012338
-
Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profile
-
Agrawal D, Chen T, Irby R, et al: Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profile. J Natl Cancer Inst 94: 513-521, 2002.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 513-521
-
-
Agrawal, D.1
Chen, T.2
Irby, R.3
-
39
-
-
26444467146
-
Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer: Results from the DAHANCA 5 randomised double-blind placebo-controlled trial
-
DOI 10.1016/S1470-2045(05)70292-8, PII S1470204505702928
-
Overgaard J, Erickson JG, Nordsmark M, et al: Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimodazole in radiotherapy of head and neck cancer: results from the DAHANCA 5 randomized double-blind placebo-controlled trial. Lancet Oncol 6: 757-764, 2005. (Pubitemid 41430716)
-
(2005)
Lancet Oncology
, vol.6
, Issue.10
, pp. 757-764
-
-
Overgaard, J.1
Eriksen, J.G.2
Nordsmark, M.3
Alsner, J.4
Horsman, M.R.5
-
40
-
-
31144451464
-
Expression of osteopontin and HGF/Met in adult soft tissue tumors
-
Bramwell VH, Tuck AB, Wilson SM, et al: Expression of osteopontin and HGF/met in adult soft tissue tumors. Cancer Biol Ther 4: 1336-1341, 2005. (Pubitemid 43131177)
-
(2005)
Cancer Biology and Therapy
, vol.4
, Issue.12
, pp. 1336-1341
-
-
Bramwell, V.H.C.1
Tuck, A.B.2
Wilson, S.M.3
Stitt, L.W.4
Cherian, A.K.5
Rorke, S.C.6
Al-Katib, W.7
Postenka, C.O.8
Chambers, A.F.9
-
41
-
-
12244267969
-
Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas
-
Le QT, Sutphin PD, Raychaudhuri S, et al: Identification of osteopontin as a prognostic plasma marker for head and neck cancer. Clin Cancer Res 9: 59-67, 2003. (Pubitemid 36109716)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.1 I
, pp. 59-67
-
-
Le, Q.-T.1
Sutphin, P.D.2
Raychaudhuri, S.3
Yu, S.C.T.4
Terris, D.J.5
Lin, H.S.6
Lum, B.7
Pinto, H.A.8
Koong, A.C.9
Giaccia, A.J.10
-
42
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
DOI 10.1038/35065016
-
Muller A, Nomey B, Soto H, et al: Involvement of chemokine receptors in breast cancer metastasis. Nature 410: 50-56, 2001. (Pubitemid 32225831)
-
(2001)
Nature
, vol.410
, Issue.6824
, pp. 50-56
-
-
Muller, A.1
Homey, B.2
Soto, H.3
Ge, N.4
Catron, D.5
Buchanan, M.E.6
McClanahan, T.7
Murphy, E.8
Yuan, W.9
Wagner, S.N.10
Barrera, J.L.11
Mohar, A.12
Verastegui, E.13
Zlotnik, A.14
-
43
-
-
33751319000
-
Stromal derived factor-1 (SDF-1/CXCl12) and CXCR4 in renal carcinoma metastasis
-
Pan J, Mestas J, Burdick MD, et al: Stromal derived factor-1 (SDF-1/CXCl12) and CXCR4 in renal carcinoma metastasis. Mol Cancer 5: 56-69, 2006.
-
(2006)
Mol Cancer
, vol.5
, pp. 56-69
-
-
Pan, J.1
Mestas, J.2
Burdick, M.D.3
-
44
-
-
18544384240
-
Hypoxia enhances the expression of autocrine motility factor and the motility of human pancreatic cancer cells
-
Niizeki H, Kobayashi M, Akakura N, et al: Hypoxia enhances the expression of autocrine motility factor and the motility of human pancreatic cancer cells. Br J Cancer 86: 1914-1919, 2002.
-
(2002)
Br J Cancer
, vol.86
, pp. 1914-1919
-
-
Niizeki, H.1
Kobayashi, M.2
Akakura, N.3
-
45
-
-
24644488689
-
Regulation of phosphoglucose isomerase/autocrine motility factor expression by hypoxia
-
DOI 10.1096/fj.05-3699com
-
Funasaka T, Yanagawa T, Hogan V, et al: Regulation of phosphoglucose isomerase/autocrine motility factor expression by hypoxia. FASEB J 19: 1422-1430, 2005. (Pubitemid 41279000)
-
(2005)
FASEB Journal
, vol.19
, Issue.11
, pp. 1422-1430
-
-
Funasaka, T.1
Yanagawa, T.2
Hogan, V.3
Raz, A.4
|