Enantioselective carbonyl reduction of eperisone in human liver microsomes

Xenobiotica

Volumn 41, Issue 9, 2011, Pages 758-763

  Yoo, Hye Hyun ^a   Kim, Nam Sun ^b   Kim, Min Jung ^d   Shin, Dongyun ^c   Shin, Jae Gook ^d   Kim, Dong Hyun ^d  

^a Hanyang University   (South Korea)

^b Korea Food and Drug Administration   (South Korea)

^c Gachon University   (South Korea)

^d Inje University College of Medicine   (South Korea)

Author keywords

11 hydroxysteroid dehydrogenase type 1; carbonyl reduction; Eperisone; microsomes; stereoselective metabolism

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; BVT 14225; CARBONYL DERIVATIVE; CYTOCHROME P450 INHIBITOR; EPERISONE; KR 66344; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; CONTROLLED STUDY; CYTOSOL; DIASTEREOISOMER; DRUG STRUCTURE; ENANTIOMER; ENANTIOSELECTIVITY; ENZYME INHIBITION; ENZYME KINETICS; ERYTHROCYTE; HUMAN; HUMAN TISSUE; ISOMER; LIVER MICROSOME; RACEMIZATION; REDUCTION;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; CARBON; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; KINETICS; MICROSOMES, LIVER; MUSCLE RELAXANTS, CENTRAL; OXIDATION-REDUCTION; PROADIFEN; PROPIOPHENONES; STEREOISOMERISM; SULFONAMIDES; THIAZOLES;

EID: 79961179091     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2011.576277     Document Type: Article

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