Modulation of drug (metoprolol succinate) release by inclusion of hydrophobic polymer in hydrophilic matrix

Drug Development and Industrial Pharmacy

Volumn 37, Issue 9, 2011, Pages 1016-1025

  Siddique, Sabahuddin ^a   Bose, Anirbandeep ^b   Khanam, Jasmina ^a  

^a JADAVPUR UNIVERSITY   (India)

^b NRI Institute of Pharmaceutical Sciences   (India)

Author keywords

Ethyl cellulose; HPMC; IVIVC; Metoprolol succinate; Response surface methodology

Indexed keywords

CALCIUM PHOSPHATE DIBASIC; ETHYL CELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; LACTOSE; METOPROLOL SUCCINATE; POLYMER;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DRUG BIOAVAILABILITY; DRUG STABILITY; DRUG STORAGE; HYDROPHILICITY; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; MATRIX TABLET; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; RESPONSE SURFACE METHOD; SCANNING ELECTRON MICROSCOPY; SINGLE DRUG DOSE; SUSTAINED DRUG RELEASE; TABLET COMPRESSION; TABLET FORMULATION; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, ORAL; ADRENERGIC BETA-1 RECEPTOR ANTAGONISTS; ANIMALS; BIOLOGICAL AVAILABILITY; CELLULOSE; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; METHYLCELLULOSE; METOPROLOL; MODELS, ANIMAL; RABBITS;

EID: 79961164640     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2011.557076     Document Type: Article

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