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Volumn 12, Issue , 2011, Pages

The protocadherins, PCDHB1 and PCDH7, are regulated by MeCP2 in neuronal cells and brain tissues: Implication for pathogenesis of Rett syndrome

Author keywords

[No Author keywords available]

Indexed keywords

METHYL CPG BINDING PROTEIN 2; SMALL INTERFERING RNA; CADHERIN; MECP2 PROTEIN, HUMAN; PCDH1 PROTEIN, HUMAN; PCDH7 PROTEIN, HUMAN;

EID: 79961120015     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-12-81     Document Type: Article
Times cited : (64)

References (58)
  • 1
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • 10.1038/13810, 10508514
    • Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet 1999, 23:185-188. 10.1038/13810, 10508514.
    • (1999) Nat Genet , vol.23 , pp. 185-188
    • Amir, R.E.1    Van den Veyver, I.B.2    Wan, M.3    Tran, C.Q.4    Francke, U.5    Zoghbi, H.Y.6
  • 2
    • 35648978121 scopus 로고    scopus 로고
    • The story of Rett syndrome: from clinic to neurobiology
    • 10.1016/j.neuron.2007.10.001, 17988628
    • Chahrour M, Zoghbi HY. The story of Rett syndrome: from clinic to neurobiology. Neuron 2007, 56:422-437. 10.1016/j.neuron.2007.10.001, 17988628.
    • (2007) Neuron , vol.56 , pp. 422-437
    • Chahrour, M.1    Zoghbi, H.Y.2
  • 3
    • 0035093830 scopus 로고    scopus 로고
    • Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
    • 10.1038/85906, 11242118
    • Chen RZ, Akbarian S, Tudor M, Jaenisch R. Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice. Nat Genet 2001, 27:327-331. 10.1038/85906, 11242118.
    • (2001) Nat Genet , vol.27 , pp. 327-331
    • Chen, R.Z.1    Akbarian, S.2    Tudor, M.3    Jaenisch, R.4
  • 4
    • 0035094767 scopus 로고    scopus 로고
    • A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
    • 10.1038/85899, 11242117
    • Guy J, Hendrich B, Holmes M, Martin JE, Bird A. A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat Genet 2001, 27:322-326. 10.1038/85899, 11242117.
    • (2001) Nat Genet , vol.27 , pp. 322-326
    • Guy, J.1    Hendrich, B.2    Holmes, M.3    Martin, J.E.4    Bird, A.5
  • 5
    • 7244243971 scopus 로고    scopus 로고
    • MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions
    • 10.1016/j.mcn.2004.07.006, 15519245
    • Kishi N, Macklis JD. MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions. Mol Cell Neurosci 2004, 27:306-321. 10.1016/j.mcn.2004.07.006, 15519245.
    • (2004) Mol Cell Neurosci , vol.27 , pp. 306-321
    • Kishi, N.1    Macklis, J.D.2
  • 6
    • 33645080930 scopus 로고    scopus 로고
    • Mecp2 deficiency is associated with learning and cognitive deficits and altered gene activity in the hippocampal region of mice
    • 10.1093/brain/awl022, 16467389
    • Pelka GJ, Watson CM, Radziewic T, Hayward M, Lahooti H, Christodoulou J, Tam PP. Mecp2 deficiency is associated with learning and cognitive deficits and altered gene activity in the hippocampal region of mice. Brain 2006, 129:887-898. 10.1093/brain/awl022, 16467389.
    • (2006) Brain , vol.129 , pp. 887-898
    • Pelka, G.J.1    Watson, C.M.2    Radziewic, T.3    Hayward, M.4    Lahooti, H.5    Christodoulou, J.6    Tam, P.P.7
  • 7
    • 34748831111 scopus 로고    scopus 로고
    • MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number
    • 10.1016/j.neuron.2007.08.018, 2198899, 17920015
    • Chao HT, Zoghbi HY, Rosenmund C. MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number. Neuron 2007, 56:58-65. 10.1016/j.neuron.2007.08.018, 2198899, 17920015.
    • (2007) Neuron , vol.56 , pp. 58-65
    • Chao, H.T.1    Zoghbi, H.Y.2    Rosenmund, C.3
  • 8
    • 0037180492 scopus 로고    scopus 로고
    • Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain
    • Tudor M, Akbarian S, Chen RZ, Jaenisch R. Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain. Proc Natl Acad Sci (USA) 2002, 99:15536-15541.
    • (2002) Proc Natl Acad Sci (USA) , vol.99 , pp. 15536-15541
    • Tudor, M.1    Akbarian, S.2    Chen, R.Z.3    Jaenisch, R.4
  • 9
    • 76849094693 scopus 로고    scopus 로고
    • Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state
    • 10.1016/j.molcel.2010.01.030, 20188665
    • Skene PJ, Illingworth RS, Webb S, Kerr AR, James KD, Turner DJ, Andrews R, Bird AP. Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state. Mol Cell 2010, 37:457-468. 10.1016/j.molcel.2010.01.030, 20188665.
    • (2010) Mol Cell , vol.37 , pp. 457-468
    • Skene, P.J.1    Illingworth, R.S.2    Webb, S.3    Kerr, A.R.4    James, K.D.5    Turner, D.J.6    Andrews, R.7    Bird, A.P.8
  • 10
    • 45849105557 scopus 로고    scopus 로고
    • MeCP2, a key contributor to neurological disease, activates and represses transcription
    • 10.1126/science.1153252, 2443785, 18511691
    • Chahrour M, Jung SY, Shaw C, Zhou X, Wong ST, Qin J, Zoghbi HY. MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 2008, 320:1224-1229. 10.1126/science.1153252, 2443785, 18511691.
    • (2008) Science , vol.320 , pp. 1224-1229
    • Chahrour, M.1    Jung, S.Y.2    Shaw, C.3    Zhou, X.4    Wong, S.T.5    Qin, J.6    Zoghbi, H.Y.7
  • 11
    • 77649339642 scopus 로고    scopus 로고
    • MeCP2 functions largely cell-autonomously, but also non-cell-autonomously, in neuronal maturation and dendritic arborization of cortical pyramidal neurons
    • 10.1016/j.expneurol.2009.12.007, 2846301, 20025874
    • Kishi N, Macklis JD. MeCP2 functions largely cell-autonomously, but also non-cell-autonomously, in neuronal maturation and dendritic arborization of cortical pyramidal neurons. Exp Neurol 2010, 222:51-58. 10.1016/j.expneurol.2009.12.007, 2846301, 20025874.
    • (2010) Exp Neurol , vol.222 , pp. 51-58
    • Kishi, N.1    Macklis, J.D.2
  • 12
    • 0242332183 scopus 로고    scopus 로고
    • Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
    • 10.1126/science.1086446, 14593183
    • Chen WG, Chang Q, Lin Y, Meissner A, West AE, Griffith EC, Jaenisch R, Greenberg ME. Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. Science 2003, 302:885-889. 10.1126/science.1086446, 14593183.
    • (2003) Science , vol.302 , pp. 885-889
    • Chen, W.G.1    Chang, Q.2    Lin, Y.3    Meissner, A.4    West, A.E.5    Griffith, E.C.6    Jaenisch, R.7    Greenberg, M.E.8
  • 13
    • 0242300612 scopus 로고    scopus 로고
    • DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation
    • 10.1126/science.1090842, 14593184
    • Martinowich K, Hattori D, Wu H, Fouse S, He F, Hu Y, Fan G, Sun YE. DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science 2003, 302:890-893. 10.1126/science.1090842, 14593184.
    • (2003) Science , vol.302 , pp. 890-893
    • Martinowich, K.1    Hattori, D.2    Wu, H.3    Fouse, S.4    He, F.5    Hu, Y.6    Fan, G.7    Sun, Y.E.8
  • 15
    • 34547118571 scopus 로고    scopus 로고
    • Cerebellar gene expression profiles of mouse models for Rett syndrome reveal novel MeCP2 targets
    • 1931432, 17584923
    • Jordan C, Li HH, Kwan HC, Francke U. Cerebellar gene expression profiles of mouse models for Rett syndrome reveal novel MeCP2 targets. BMC Med Genet 2007, 8:36. 1931432, 17584923.
    • (2007) BMC Med Genet , vol.8 , pp. 36
    • Jordan, C.1    Li, H.H.2    Kwan, H.C.3    Francke, U.4
  • 16
    • 33846839170 scopus 로고    scopus 로고
    • Methyl CpG-binding protein 2 (a mutation of which causes Rett syndrome) directly regulates insulin-like growth factor binding protein 3 in mouse and human brains
    • 10.1097/nen.0b013e3180302078, 17278996
    • Itoh M, Ide S, Takashima S, Kudo S, Nomura Y, Segawa M, Kubota T, Mori H, Tanaka S, Horie H, Tanabe Y, Goto Y. Methyl CpG-binding protein 2 (a mutation of which causes Rett syndrome) directly regulates insulin-like growth factor binding protein 3 in mouse and human brains. J Neuropathol Exp Neurol 2007, 66:117-123. 10.1097/nen.0b013e3180302078, 17278996.
    • (2007) J Neuropathol Exp Neurol , vol.66 , pp. 117-123
    • Itoh, M.1    Ide, S.2    Takashima, S.3    Kudo, S.4    Nomura, Y.5    Segawa, M.6    Kubota, T.7    Mori, H.8    Tanaka, S.9    Horie, H.10    Tanabe, Y.11    Goto, Y.12
  • 18
    • 77952553247 scopus 로고    scopus 로고
    • CDKL5 is a brain MeCP2 target gene regulated by DNA methylation
    • 10.1016/j.nbd.2010.02.014, 20211261
    • Carouge D, Host L, Aunis D, Zwiller J, Anglard P. CDKL5 is a brain MeCP2 target gene regulated by DNA methylation. Neurobiol Dis 2010, 38:414-424. 10.1016/j.nbd.2010.02.014, 20211261.
    • (2010) Neurobiol Dis , vol.38 , pp. 414-424
    • Carouge, D.1    Host, L.2    Aunis, D.3    Zwiller, J.4    Anglard, P.5
  • 19
    • 4143096081 scopus 로고    scopus 로고
    • Comparative genomic hybridization (CGH)-arrays pave the way for identification of novel cancer-related genes
    • 10.1111/j.1349-7006.2004.tb02486.x, 15245590
    • Inazawa J, Inoue J, Imoto I. Comparative genomic hybridization (CGH)-arrays pave the way for identification of novel cancer-related genes. Cancer Sci 2004, 95:559-563. 10.1111/j.1349-7006.2004.tb02486.x, 15245590.
    • (2004) Cancer Sci , vol.95 , pp. 559-563
    • Inazawa, J.1    Inoue, J.2    Imoto, I.3
  • 20
    • 28544444942 scopus 로고    scopus 로고
    • Methylation-associated silencing of the nuclear receptor 1I2 gene in advanced-type neuroblastomas, identified by bacterial artificial chromosome array-based methylated CpG island amplification
    • 10.1158/0008-5472.CAN-05-1073, 16288011
    • Misawa A, Inoue J, Sugino Y, Hosoi H, Sugimoto T, Hosoda F, Ohki M, Imoto I, Inazawa J. Methylation-associated silencing of the nuclear receptor 1I2 gene in advanced-type neuroblastomas, identified by bacterial artificial chromosome array-based methylated CpG island amplification. Cancer Res 2005, 65:10233-10242. 10.1158/0008-5472.CAN-05-1073, 16288011.
    • (2005) Cancer Res , vol.65 , pp. 10233-10242
    • Misawa, A.1    Inoue, J.2    Sugino, Y.3    Hosoi, H.4    Sugimoto, T.5    Hosoda, F.6    Ohki, M.7    Imoto, I.8    Inazawa, J.9
  • 21
    • 24044523177 scopus 로고    scopus 로고
    • DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG
    • 10.1016/j.molcel.2005.07.021, 16137622
    • Klose RJ, Sarraf SA, Schmiedeberg L, McDermott SM, Stancheva I, Bird AP. DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG. Mol Cell 2005, 19:667-678. 10.1016/j.molcel.2005.07.021, 16137622.
    • (2005) Mol Cell , vol.19 , pp. 667-678
    • Klose, R.J.1    Sarraf, S.A.2    Schmiedeberg, L.3    McDermott, S.M.4    Stancheva, I.5    Bird, A.P.6
  • 22
    • 15544382113 scopus 로고    scopus 로고
    • Homologous pairing of 15q11-13 imprinted domains in brain is developmentally regulated but deficient in Rett and autism samples
    • 10.1093/hmg/ddi073, 15689352
    • Thatcher KN, Peddada S, Yasui DH, Lasalle JM. Homologous pairing of 15q11-13 imprinted domains in brain is developmentally regulated but deficient in Rett and autism samples. Hum Mol Genet 2005, 14:785-797. 10.1093/hmg/ddi073, 15689352.
    • (2005) Hum Mol Genet , vol.14 , pp. 785-797
    • Thatcher, K.N.1    Peddada, S.2    Yasui, D.H.3    Lasalle, J.M.4
  • 24
    • 0035096550 scopus 로고    scopus 로고
    • Rett syndrome model suggests MECP2 gives neurons the quiet they need to think
    • 10.1038/85970, 11276217
    • Carter AR, Segal RA. Rett syndrome model suggests MECP2 gives neurons the quiet they need to think. Nat Neurosci 2001, 4:342-343. 10.1038/85970, 11276217.
    • (2001) Nat Neurosci , vol.4 , pp. 342-343
    • Carter, A.R.1    Segal, R.A.2
  • 25
    • 77249137168 scopus 로고    scopus 로고
    • Principles and challenges of genome-wide DNA methylation analysis
    • Laird PW. Principles and challenges of genome-wide DNA methylation analysis. Nat Rev Genet 2010, 11:191-203.
    • (2010) Nat Rev Genet , vol.11 , pp. 191-203
    • Laird, P.W.1
  • 26
    • 0037444026 scopus 로고    scopus 로고
    • The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties
    • 10.1093/nar/gkg249, 152853, 12626718
    • Fraga MF, Ballestar E, Montoya G, Taysavang P, Wade PA, Esteller M. The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties. Nucleic Acids Res 2003, 31:1765-1774. 10.1093/nar/gkg249, 152853, 12626718.
    • (2003) Nucleic Acids Res , vol.31 , pp. 1765-1774
    • Fraga, M.F.1    Ballestar, E.2    Montoya, G.3    Taysavang, P.4    Wade, P.A.5    Esteller, M.6
  • 27
    • 33846637375 scopus 로고    scopus 로고
    • Multiple modes of interaction between the methylated DNA binding protein MeCP2 and chromatin
    • 10.1128/MCB.01593-06, 1800686, 17101771
    • Nikitina T, Shi X, Ghosh RP, Horowitz-Scherer RA, Hansen JC, Woodcock CL. Multiple modes of interaction between the methylated DNA binding protein MeCP2 and chromatin. Mol Cell Biol 2007, 27:864-877. 10.1128/MCB.01593-06, 1800686, 17101771.
    • (2007) Mol Cell Biol , vol.27 , pp. 864-877
    • Nikitina, T.1    Shi, X.2    Ghosh, R.P.3    Horowitz-Scherer, R.A.4    Hansen, J.C.5    Woodcock, C.L.6
  • 28
    • 0034657319 scopus 로고    scopus 로고
    • Cadherin superfamily genese: functions, genomic organaization, and neurologic diversity
    • Yagi T, Takeichi M. Cadherin superfamily genese: functions, genomic organaization, and neurologic diversity. Genes Dev 2000, 14:1169-1180.
    • (2000) Genes Dev , vol.14 , pp. 1169-1180
    • Yagi, T.1    Takeichi, M.2
  • 29
  • 32
    • 57649186936 scopus 로고    scopus 로고
    • Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence
    • 10.1016/j.psychres.2007.08.011, 19054571
    • Gregório SP, Sallet PC, Do KA, Lin E, Gattaz WF, Dias-Neto E. Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence. Psychiatry Res 2009, 165:1-9. 10.1016/j.psychres.2007.08.011, 19054571.
    • (2009) Psychiatry Res , vol.165 , pp. 1-9
    • Gregório, S.P.1    Sallet, P.C.2    Do, K.A.3    Lin, E.4    Gattaz, W.F.5    Dias-Neto, E.6
  • 33
    • 60249083798 scopus 로고    scopus 로고
    • Evidence for positive selection on Protocadherin Y gene in Homo sapiens: implications for schizophrenia
    • 10.1016/j.schres.2008.09.015, 18938061
    • Kalmady SV, Venkatasubramanian G. Evidence for positive selection on Protocadherin Y gene in Homo sapiens: implications for schizophrenia. Schizophr Res 2009, 108:299-300. 10.1016/j.schres.2008.09.015, 18938061.
    • (2009) Schizophr Res , vol.108 , pp. 299-300
    • Kalmady, S.V.1    Venkatasubramanian, G.2
  • 34
    • 33745216678 scopus 로고    scopus 로고
    • The role and expression of the protocadherin-alpha clusters in the CNS
    • 10.1016/j.conb.2006.05.003, 16697637
    • Hirayama T, Yagi T. The role and expression of the protocadherin-alpha clusters in the CNS. Curr Opin Neurobiol 2006, 16:336-342. 10.1016/j.conb.2006.05.003, 16697637.
    • (2006) Curr Opin Neurobiol , vol.16 , pp. 336-342
    • Hirayama, T.1    Yagi, T.2
  • 35
    • 44249108389 scopus 로고    scopus 로고
    • Clustered protocadherin family
    • Yagi T. Clustered protocadherin family. Dev Growth Differ 2008, 50:S131-S140.
    • (2008) Dev Growth Differ , vol.50
    • Yagi, T.1
  • 36
    • 39049112879 scopus 로고    scopus 로고
    • Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system
    • 10.1111/j.1460-9568.2008.06052.x, 18279309
    • Junghans D, Heidenreich M, Hack I, Taylor V, Frotscher M, Kemler R. Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system. Eur J Neurosci 2008, 27:559-571. 10.1111/j.1460-9568.2008.06052.x, 18279309.
    • (2008) Eur J Neurosci , vol.27 , pp. 559-571
    • Junghans, D.1    Heidenreich, M.2    Hack, I.3    Taylor, V.4    Frotscher, M.5    Kemler, R.6
  • 37
    • 0029059624 scopus 로고
    • Pervasive neuroanatomic abnormalities of the brain in three cases of Rett's syndrome
    • Bauman ML, Kemper TL, Arin DM. Pervasive neuroanatomic abnormalities of the brain in three cases of Rett's syndrome. Neurology 1995, 45:1581-1586.
    • (1995) Neurology , vol.45 , pp. 1581-1586
    • Bauman, M.L.1    Kemper, T.L.2    Arin, D.M.3
  • 38
    • 0028904853 scopus 로고
    • Selective dendritic alterations in the cortex of Rett syndrome
    • 10.1097/00005072-199503000-00006, 7876888
    • Armstrong D, Dunn JK, Antalffy B, Trivedi R. Selective dendritic alterations in the cortex of Rett syndrome. J Neuropathol Exp Neurol 1995, 54:195-201. 10.1097/00005072-199503000-00006, 7876888.
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 195-201
    • Armstrong, D.1    Dunn, J.K.2    Antalffy, B.3    Trivedi, R.4
  • 39
    • 0031761177 scopus 로고    scopus 로고
    • Decreased dendritic branching in frontal, motor and limbic cortex in Rett syndrome compared with trisomy 21
    • 10.1097/00005072-199811000-00003, 9825937
    • Armstrong DD, Dunn K, Antalffy B. Decreased dendritic branching in frontal, motor and limbic cortex in Rett syndrome compared with trisomy 21. J Neuropathol Exp Neurol 1998, 57:1013-1017. 10.1097/00005072-199811000-00003, 9825937.
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 1013-1017
    • Armstrong, D.D.1    Dunn, K.2    Antalffy, B.3
  • 40
    • 45549101475 scopus 로고    scopus 로고
    • Relationship between DNA methylation states and transcription of individual isoforms encoded by the protocadherin-alpha gene cluster
    • 10.1074/jbc.M709648200, 18204046
    • Kawaguchi M, Toyama T, Kaneko R, Hirayama T, Kawamura Y, Yagi T. Relationship between DNA methylation states and transcription of individual isoforms encoded by the protocadherin-alpha gene cluster. J Biol Chem 2008, 283:12064-12075. 10.1074/jbc.M709648200, 18204046.
    • (2008) J Biol Chem , vol.283 , pp. 12064-12075
    • Kawaguchi, M.1    Toyama, T.2    Kaneko, R.3    Hirayama, T.4    Kawamura, Y.5    Yagi, T.6
  • 41
    • 0031836266 scopus 로고    scopus 로고
    • Cloning, expression analysis, and chromosomal localization of BH-protocadherin (PCDH7), a novel member of the cadherin superfamily
    • 10.1006/geno.1998.5271, 9615233
    • Yoshida K, Yoshitomo-Nakagawa K, Seki N, Sasaki M, Sugano S. Cloning, expression analysis, and chromosomal localization of BH-protocadherin (PCDH7), a novel member of the cadherin superfamily. Genomics 1998, 49:458-461. 10.1006/geno.1998.5271, 9615233.
    • (1998) Genomics , vol.49 , pp. 458-461
    • Yoshida, K.1    Yoshitomo-Nakagawa, K.2    Seki, N.3    Sasaki, M.4    Sugano, S.5
  • 42
    • 34547103747 scopus 로고    scopus 로고
    • Spatiotemporal expression pattern of non-clustered protocadherin family members in the developing rat brain
    • 10.1016/j.neuroscience.2007.03.052, 17614211
    • Kim SY, Chung HS, Sun W, Kim H. Spatiotemporal expression pattern of non-clustered protocadherin family members in the developing rat brain. Neuroscience 2007, 147:996-1021. 10.1016/j.neuroscience.2007.03.052, 17614211.
    • (2007) Neuroscience , vol.147 , pp. 996-1021
    • Kim, S.Y.1    Chung, H.S.2    Sun, W.3    Kim, H.4
  • 43
    • 75449117701 scopus 로고    scopus 로고
    • Expression of classic cadherins and delta-protocadherins in the developing ferret retina
    • 10.1186/1471-2202-10-153, 2811116, 20028529
    • Etzrodt J, Krishna-K K, Redies C. Expression of classic cadherins and delta-protocadherins in the developing ferret retina. BMC Neurosci 2009, 10:153. 10.1186/1471-2202-10-153, 2811116, 20028529.
    • (2009) BMC Neurosci , vol.10 , pp. 153
    • Etzrodt, J.1    Krishna-K, K.2    Redies, C.3
  • 44
    • 0141868880 scopus 로고    scopus 로고
    • Fibroblast cell shape and adhesion in vitro is altered by overexpression of the 7a and 7b isoforms of protocadherin 7, but not the 7c isoform
    • Yoshida K. Fibroblast cell shape and adhesion in vitro is altered by overexpression of the 7a and 7b isoforms of protocadherin 7, but not the 7c isoform. Cell Mol Biol Lett 2003, 8:735-741.
    • (2003) Cell Mol Biol Lett , vol.8 , pp. 735-741
    • Yoshida, K.1
  • 45
    • 45749147105 scopus 로고    scopus 로고
    • MeCP2 knockdown reveals DNA methylation-independent gene repression of target genes in living cells and a bias in the cellular location of target gene products
    • 10.1266/ggs.83.199, 18506103
    • Yakabe S, Soejima H, Yatsuki H, Tominaga H, Zhao W, Higashimoto K, Joh K, Kudo S, Miyazaki K, Mukai T. MeCP2 knockdown reveals DNA methylation-independent gene repression of target genes in living cells and a bias in the cellular location of target gene products. Genes Genet Syst 2008, 83:199-208. 10.1266/ggs.83.199, 18506103.
    • (2008) Genes Genet Syst , vol.83 , pp. 199-208
    • Yakabe, S.1    Soejima, H.2    Yatsuki, H.3    Tominaga, H.4    Zhao, W.5    Higashimoto, K.6    Joh, K.7    Kudo, S.8    Miyazaki, K.9    Mukai, T.10
  • 47
    • 68549087008 scopus 로고    scopus 로고
    • Neuronal differentiation of neural precursor cells is promoted by the methyl-CpG-binding protein MeCP2
    • 10.1016/j.expneurol.2009.05.001, 19427855
    • Tsujimura K, Abematsu M, Kohyama J, Namihira M, Nakashima K. Neuronal differentiation of neural precursor cells is promoted by the methyl-CpG-binding protein MeCP2. Exp Neurol 2009, 219:104-111. 10.1016/j.expneurol.2009.05.001, 19427855.
    • (2009) Exp Neurol , vol.219 , pp. 104-111
    • Tsujimura, K.1    Abematsu, M.2    Kohyama, J.3    Namihira, M.4    Nakashima, K.5
  • 48
    • 77953122395 scopus 로고    scopus 로고
    • Diminished prevalence but preserved synaptic distribution of N-methyl-d-aspartate receptor subunits in the methyl CpG binding protein 2(MeCP2)-null mouse brain
    • 10.1016/j.neuroscience.2010.03.065, 20381590
    • Maliszewska-Cyna E, Bawa D, Eubanks JH. Diminished prevalence but preserved synaptic distribution of N-methyl-d-aspartate receptor subunits in the methyl CpG binding protein 2(MeCP2)-null mouse brain. Neuroscience 2010, 168:624-632. 10.1016/j.neuroscience.2010.03.065, 20381590.
    • (2010) Neuroscience , vol.168 , pp. 624-632
    • Maliszewska-Cyna, E.1    Bawa, D.2    Eubanks, J.H.3
  • 49
    • 0242300623 scopus 로고    scopus 로고
    • Postnatal neurodevelopmental disorders: meeting at the synapse?
    • 10.1126/science.1089071, 14593168
    • Zoghbi HY. Postnatal neurodevelopmental disorders: meeting at the synapse?. Science 2003, 302:826-830. 10.1126/science.1089071, 14593168.
    • (2003) Science , vol.302 , pp. 826-830
    • Zoghbi, H.Y.1
  • 51
    • 33645355913 scopus 로고    scopus 로고
    • Mechanisms of disease: neurogenetics of MeCP2 deficiency
    • 10.1038/ncpneuro0148, 16932552
    • Francke U. Mechanisms of disease: neurogenetics of MeCP2 deficiency. Nat Clin Pract Neurol 2006, 2:212-221. 10.1038/ncpneuro0148, 16932552.
    • (2006) Nat Clin Pract Neurol , vol.2 , pp. 212-221
    • Francke, U.1
  • 53
    • 77951207088 scopus 로고    scopus 로고
    • Synaptic circuit abnormalities of motor-frontal layer 2/3 pyramidal neurons in a mutant mouse model of Rett syndrome
    • 10.1016/j.nbd.2010.01.018, 2854239, 20138994
    • Wood L, Shepherd GM. Synaptic circuit abnormalities of motor-frontal layer 2/3 pyramidal neurons in a mutant mouse model of Rett syndrome. Neurobiol Dis 2010, 38:281-287. 10.1016/j.nbd.2010.01.018, 2854239, 20138994.
    • (2010) Neurobiol Dis , vol.38 , pp. 281-287
    • Wood, L.1    Shepherd, G.M.2
  • 54
    • 77952973905 scopus 로고    scopus 로고
    • MeCP2 is required for normal development of GABAergic circuits in the thalamus
    • 10.1152/jn.00601.2009, 2867574, 20200124
    • Zhang ZW, Zak JD, Liu H. MeCP2 is required for normal development of GABAergic circuits in the thalamus. J Neurophysiol 2010, 103:2470-2481. 10.1152/jn.00601.2009, 2867574, 20200124.
    • (2010) J Neurophysiol , vol.103 , pp. 2470-2481
    • Zhang, Z.W.1    Zak, J.D.2    Liu, H.3
  • 55
    • 2542622017 scopus 로고    scopus 로고
    • Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma
    • 10.1158/0008-5472.CAN-04-0172, 15172977
    • Sonoda I, Imoto I, Inoue J, Shibata T, Shimada Y, Chin K, Imamura M, Amagasa T, Gray JW, Hirohashi S, Inazawa J. Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma. Cancer Res 2004, 64:3741-3747. 10.1158/0008-5472.CAN-04-0172, 15172977.
    • (2004) Cancer Res , vol.64 , pp. 3741-3747
    • Sonoda, I.1    Imoto, I.2    Inoue, J.3    Shibata, T.4    Shimada, Y.5    Chin, K.6    Imamura, M.7    Amagasa, T.8    Gray, J.W.9    Hirohashi, S.10    Inazawa, J.11
  • 56
    • 0033563165 scopus 로고    scopus 로고
    • Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification
    • Toyota M, Ho C, Ahuja N, Jair KW, Li Q, Ohe-Toyota M, Baylin SB, Issa JP. Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification. Cancer Res 1999, 59:2307-2312.
    • (1999) Cancer Res , vol.59 , pp. 2307-2312
    • Toyota, M.1    Ho, C.2    Ahuja, N.3    Jair, K.W.4    Li, Q.5    Ohe-Toyota, M.6    Baylin, S.B.7    Issa, J.P.8
  • 57
    • 34347347173 scopus 로고    scopus 로고
    • Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters
    • 10.1128/MCB.00073-07, 1951474, 17452465
    • Hwang CK, Song KY, Kim CS, Choi HS, Guo XH, Law PY, Wei LN, Loh HH. Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters. Mol Cell Biol 2007, 27:4720-4736. 10.1128/MCB.00073-07, 1951474, 17452465.
    • (2007) Mol Cell Biol , vol.27 , pp. 4720-4736
    • Hwang, C.K.1    Song, K.Y.2    Kim, C.S.3    Choi, H.S.4    Guo, X.H.5    Law, P.Y.6    Wei, L.N.7    Loh, H.H.8
  • 58
    • 0033588221 scopus 로고    scopus 로고
    • Cell cycle-dependent switch of up-and down-regulation of human hsp70 gene expression by interaction between c-Myc and CBF/NF-Y
    • 10.1074/jbc.274.34.24270, 10446203
    • Taira T, Sawai M, Ikeda M, Tamai K, Iguchi-Ariga SM, Ariga H. Cell cycle-dependent switch of up-and down-regulation of human hsp70 gene expression by interaction between c-Myc and CBF/NF-Y. J Biol Chem 1999, 274:24270-24279. 10.1074/jbc.274.34.24270, 10446203.
    • (1999) J Biol Chem , vol.274 , pp. 24270-24279
    • Taira, T.1    Sawai, M.2    Ikeda, M.3    Tamai, K.4    Iguchi-Ariga, S.M.5    Ariga, H.6


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