Assessment of tumor radioresponsiveness and metastatic potential by dynamic contrast-enhanced magnetic resonance imaging

International Journal of Radiation Oncology Biology Physics

Volumn 81, Issue 1, 2011, Pages 255-261

  Øvrebø, Kirsti Marie ^a   Gulliksrud, Kristine ^a   Mathiesen, Berit ^a   Rofstad, Einar K ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

DCE MRI; Hypoxia; Metastatic potential; Radioresponsiveness; Xenografts

Indexed keywords

DCE-MRI; HYPOXIA; METASTATIC POTENTIAL; RADIORESPONSIVENESS; XENOGRAFTS;

ACETIC ACID; BODY FLUIDS; GADOLINIUM; MAGNETIC RESONANCE IMAGING; MAMMALS; NONINVASIVE MEDICAL PROCEDURES; PATHOLOGY; RADIOTHERAPY; RESONANCE;

TUMORS;

GADOLINIUM; PENTETIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER RADIOTHERAPY; CANCER THERAPY; CELL SURVIVAL; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; FEMALE; HYPOXIA; IN VITRO STUDY; IN VIVO STUDY; LYMPH NODE METASTASIS; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHARMACOKINETICS; PRIMARY TUMOR; PRIORITY JOURNAL; RADIATION DOSE; RADIATION RESPONSE; RADIOBIOLOGY; RADIOSENSITIVITY; TISSUE OXYGENATION; TUMOR MODEL; TUMOR XENOGRAFT;

ANIMALS; CELL HYPOXIA; CELL LINE, TUMOR; CELL SURVIVAL; CONTRAST MEDIA; DOSE FRACTIONATION; FEMALE; GADOLINIUM DTPA; HUMANS; LYMPHATIC METASTASIS; MAGNETIC RESONANCE IMAGING; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED BALB C; MICE, NUDE; MONTE CARLO METHOD; RADIATION TOLERANCE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79961113334     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2011.04.008     Document Type: Article

References (30)

1. J.M. Brown, and A.J. Giaccia The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy Cancer Res 58 1998 1408 1416 (Pubitemid 28193601)
2. M. Höckel, and P. Vaupel Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects J Natl Cancer Inst 93 2001 266 276 (Pubitemid 32219813)
3. R. Cairns, I. Papandreou, and N. Denko Overcoming physiologic barriers to cancer treatment by molecularly targeting the tumor microenvironment Mol Cancer Res 4 2006 61 70
4. A.L. Harris Hypoxia - a key regulatory factor in tumour growth Nat Rev Cancer 2 2002 38 47 (Pubitemid 37328806)
5. P. Vaupel Tumor microenvironmental physiology and its implications for radiation oncology Semin Radiat Oncol 14 2004 198 206 (Pubitemid 38903223)
6. R.K. Jain Determinants of tumor blood flow: A review Cancer Res 48 1998 2641 2658
7. P. Vaupel, F. Kallinowski, and P. Okunieff Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors Cancer Res 49 1989 6449 6465 (Pubitemid 20008770)
8. N. Hylton Dynamic contrast-enhanced magnetic resonance imaging as an imaging biomarker J Clin Oncol 24 2006 3293 3298 (Pubitemid 46622069)
9. M.A. Zahra, K.G. Hollingsworth, and E. Sala Dynamic contrast-enhanced MRI as a predictor of tumour response to radiotherapy Lancet Oncol 8 2007 63 74 (Pubitemid 44943092)
10. D. Jennings, N. Raghunand, and R.J. Gillies Imaging hemodynamics Cancer Metastasis Rev 27 2008 589 613
11. I.C. Benjaminsen, B.A. Graff, and K.G. Brurberg Assessment of tumor blood perfusion by high-resolution DCE-MRI: A preclinical study of human melanoma xenografts Magn Reson Med 52 2004 269 276 (Pubitemid 39025270)
12. K.G. Brurberg, I.C. Benjaminsen, and L.M.R. Dørum Fluctuations in tumor blood perfusion assessed by dynamic-contrast enhanced MRI Magn Reson Med 58 2007 473 481 (Pubitemid 350154957)
13. T.A.M. Egeland, T.G. Simonsen, and J.V. Gaustad Dynamic contrast-enhanced magnetic resonance imaging of tumors: Preclinical validation of parametric images Radiat Res 172 2009 339 347
14. J.V. Gaustad, K.G. Brurberg, and T.G. Simonsen Tumor vascularity assessed by magnetic resonance imaging and intravital microscopy imaging Neoplasia 10 2008 354 362 (Pubitemid 351483575)
15. K. Gulliksrud, K.G. Brurberg, and E.K. Rofstad Dynamic contrast-enhanced magnetic resonance imaging of tumor interstitial fluid pressure Radiother Oncol 91 2009 107 113
16. T.A.M. Egeland, J.V. Gaustad, and I.K. Vestvik Assessment of fraction of radiobiologically hypoxic cells in human melanoma xenografts by dynamic contrast-enhanced MRI Magn Reson Med 55 2006 874 882
17. 1-weighted MRI of a diffusable tracer: Standardized quantities and symbols J Magn Reson Imaging 10 1999 223 232 (Pubitemid 29463104)
18. E.K. Rofstad, E.B.M. Ruud, and B. Mathiesen Associations between radiocurability and interstitial fluid pressure in human tumor xenografts without hypoxic tissue Clin Cancer Res 16 2010 936 945
19. E.K. Rofstad, and B. Mathiesen Metastasis in melanoma xenografts is associated with tumor microvascular density rather than extent of hypoxia Neoplasia 12 2010 889 898
20. E.K. Rofstad, K. Galappathi, and B. Mathiesen Fluctuating and diffusion-limited hypoxia in hypoxia-induced metastasis Clin Cancer Res 13 2007 1971 1978 (Pubitemid 46649862)
21. E.K. Rofstad, H. Rasmussen, and K. Galappathi Hypoxia promotes lymph node metastasis in human melanoma xenografts by up-regulating the urokinase-type plasminogen activator receptor Cancer Res 62 2002 1847 1853 (Pubitemid 34408512)
22. K. Hittmair, G. Gomiscek, and K. Langenberger Method for the quantitative assessment of contrast agent uptake in dynamic contrast-enhanced MRI Magn Reson Med 31 1994 567 571 (Pubitemid 24129954)
23. E.K. Rofstad Hypoxia and reoxygenation in human melanoma xenografts Int J Radiat Oncol Biol Phys 17 1989 81 89 (Pubitemid 19173242)
24. H. Hawighorst, W. Weikel, and P.G. Knapstein Angiogenic activity of cervical carcinoma: Assessment by functional magnetic resonance imaging-based parameters and a histomorphological approach in correlation with disease outcome Clin Cancer Res 4 1998 2305 2312 (Pubitemid 28477893)
25. H. Lyng, A.O. Vorren, and K. Sundfør Assessment of tumor oxygenation in human cervical carcinoma by use of dynamic Gd-DTPA-enhanced MR imaging J Magn Reson Imaging 14 2001 750 756 (Pubitemid 33101534)
26. J.A. Loncaster, B.M. Carrington, and J.R. Sykes Prediction of radiotherapy outcome using dynamic contrast-enhanced MRI of carcinoma of the cervix Int J Radiat Oncol Biol Phys 54 2002 759 767
27. S.I.K. Semple, V.N. Harry, and D.E. Parkin A combined pharmacokinetic and radiologic assessment of dynamic contrast-enhanced magnetic resonance imaging predicts response to chemoradiation in locally advanced cervical cancer Int J Radiat Oncol Biol Phys 75 2009 611 617
28. W.T.C. Yuh, N.A. Mayr, and D. Jarjoura Predicting control of primary tumor and survival by DCE MRI during early therapy in cervical cancer Invest Radiol 44 2009 343 350
29. L.Z. Li, R. Zhou, H.N. Xu, and L. Moon Quantitative magnetic resonance and optical imaging biomarkers of melanoma metastatic potential Proc Natl Acad Sci USA 106 2009 6608 6613
30. M.O. Leach, K.M. Brindle, and J.L. Evelhoch The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: Issues and recommendations Br J Cancer 92 2005 1599 1610 (Pubitemid 40756468)