Role of prostaglandin pathway and alendronate-based carriers to enhance statin-induced bone

Molecular Pharmaceutics

Volumn 8, Issue 4, 2011, Pages 1035-1042

  Lee, Yeonju ^a   Liu, Xinming ^b   Nawshad, Ali ^a   Marx, David B ^c   Wang, Dong ^b   Reinhardt, Richard A ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

alendronate; bone growth; cyclodextrin; PGE 2; simvastatin

Indexed keywords

ALCOHOL; ALENDRONATE BETA CYCLODEXTRIN CONJUGATE; ALENDRONIC ACID; DRUG CARRIER; MESSENGER RNA; PROSTAGLANDIN; SIMVASTATIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; BONE GROWTH; CELL STIMULATION; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; FEMALE; FIBROBLAST; INJECTION SITE; MANDIBLE; MORPHOMETRICS; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; RAT; REVIEW; SYNTHESIS;

ALENDRONATE; ANIMALS; CELL LINE; CYCLODEXTRINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLASTS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INTRAMOLECULAR OXIDOREDUCTASES; MICE; MODELS, BIOLOGICAL; OSTEOBLASTS; POLYMERASE CHAIN REACTION; PROSTAGLANDINS; RATS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; SIGNAL TRANSDUCTION; SIMVASTATIN;

EID: 79961041640     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200045p     Document Type: Review

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