Controlled release of simvastatin acid using cyclodextrin inclusion system

Dental Materials Journal

Volumn 26, Issue 3, 2007, Pages 451-456

  Yoshinari, Masao ^a   Matsuzaka, Kenichi ^a   Hashimoto, Sadamitsu ^a   Ishihara, Kazuyuki ^a   Inoue, Takashi ^a   Oda, Yutaka ^a   Ide, Takaharu ^b   Tanaka, Teruo ^b  

^a TOKYO DENTAL COLLEGE   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Controlled drug release; Cyclodextrin derivative; Simvastatin acid

Indexed keywords

BIOMATERIAL; BONE GROWTH FACTORS; CYCLODEXTRIN; DRUG DERIVATIVE; PROTEIN; SIMVASTATIN; SIMVASTATIN ACID; TITANIUM; UNCLASSIFIED DRUG;

ARTICLE; CHEMISTRY; DELAYED RELEASE FORMULATION; PH;

COATED MATERIALS, BIOCOMPATIBLE; CYCLODEXTRINS; DELAYED-ACTION PREPARATIONS; HYDROGEN-ION CONCENTRATION; PROTEINS; SIMVASTATIN; TITANIUM;

EID: 35549013203     PISSN: 02874547     EISSN: None     Source Type: Journal    
DOI: 10.4012/dmj.26.451     Document Type: Article

References (21)

1. Mundy G, Garrett R, Harris S, Chan J, Chen D, Rossini G, Boyce B, Zhao M, Gutierrez G. Stimulation of bone formation in vitro and in rodents by statins. Science 1999; 286:1946-1949.
2. Garrett IR, Gutierrez G, Mundy GR. Statins and bone formation. Curr Pharm Des 2001; 7:715-736.
3. Ayukawa Y, Okamura A., Koyano K. Simvastatin stimulates bone formation around titanium implants in rat tibiae. Clin Oral Impl Res 2004; 15:346-350.
4. von Stechow D, Fish S, Yahalom D, Bab I, Chorev M, Müller R, Alexander JM. Does simvastatin stimulate bone formation in vivo? BMC Musculoskelet Disord 2003; 4:1-10.
5. Prueksaritanont T, Qiu Y, Mu L, Michel K, Brunner J, Richards KM, Lin JH. Interconversion pharmacokinetics of simvastatin and its hydroxy acid in dogs: effects of gemfibrozil. Pharm Res 2005; 22:1101-1109.
6. Yoshinari M, Hayakawa T, Matsuzaka K, Inoue T, Oda Y, Shimono M, Ide T, Tanaka T. Oxygen plasma surface modification enhances immobilization of simvastatin acid. Biomedical Res 2006; 27: 29-36.
7. Hailstones D, Sleer LS, Parton RG, Stanley KK. Regulation of caveolin and caveolae by cholesterol in MDCK cells. J Lipid Res 1998; 39:369-379.
8. Uekama K. Design and evaluation of cyclodextrin-based drug formulation. Chem Phram Bull 2004; 52:900-915.
9. Manca ML, Zaru M, Ennas G, Valenti D, Sinico C, Loy G, Fadda AM. Diclofenac-β-cyclodextrin binary systems: physicochemical characterization and in vitro dissolution and diffusion studies. AAPS Pharm Sci Tech 2005; 6:464-472.
10. Yue IC, Poff J, Cortes ME, Sinisterra RD, Faris CB. A novel polymeric chlorhexidine delivery device for the treatment of periodontal disease. Biomaterials 2004; 25:3743-3750.
11. Domingues ZR, Cortes ME, Gomes TA, Diniz HF, Freitas CS, Gomes JB, Faria AMC, Sinisterra RD. Bioactive glass as a drug delivery system of tetracycline and tetracycline associated with b-cyclodextrin. Biomaterials 2004; 25:327-333.
12. Thompson DO. Cyclodextrins-enabling excipients: their present and future use in pharmaceuticals. Crit Rev Ther Drug Carrier Syst 1997; 14:1-104.
13. Masson M, Loftsson T, Masson G, Stefànsson ES. Cyclodextrins as permeation enhancers: some theoretical evaluations and in vitro testing. J Control Release 1999; 59:107-118.
14. Wang L, Asgharnejad M. Second-derivative UV spectrometric determination of simvastatin in its tablet dosage form. Pharm Biomed Anal 2000; 21:1243-1248.
15. Whang K, McDonald J, Khan A, Satsangi N. A novel osteotropic biomaterial OG-PLG: Synthesis and in vitro release. J Biomed Mater Res A. 2005; 74:237-246.
16. Challa R, Ahuja A, Ali J, Khar RK. Cyclodextrins in drug delivery: an updated review. AAPS Pharm Sci Tech 2005; 6:329-357.
17. Tros de Ilarduya MC, Martin C, Goni MM, Martinez-Oharriz MC. Solubilization and interaction of sulindac with beta-cyclodextrin in the solid state and in aqueous solution. Drug Dev Ind Pharm 1998; 24:301-306.
18. Zarzycki PK, Lamparczyk H. The equilibrium constant of β-cyclodextrin-phenolphtalein complex; influence of temperature and tetrahydrofuran addition. J Pharm Biomed Anal 1998; 18:165-179.
19. Ikeda Y, Kimura K, Hirayama F, Arima H, Uekama K. Controlled release of a water-soluble drug, Captopril, by a combination of hydrophilic and hydrophobic cyclodextrin derivatives. J Control Release 2000; 66:271-280.
20. Trapani G, Lopedota A, Boghetich G, Latrofa A, Franco M, Sanna E, Liso G. Encapsulation and release of the hypnotic agent zolpidem from biodegradable polymer microparticles containing hydroxypropyl-beta-cyclodextrin. Int J Pharm 2003; 268:47-57.
21. Uekama K, Horikawa T, Yamanaka M, Hirayama F. Peracylated β-cyclodextrins as novel sustained-release carriers for a water-soluble drug, molsidomine. J Pharm Pharmacol 1994; 46:714-717.