The effect of local simvastatin delivery strategies on mandibular bone formation in vivo

Biomaterials

Volumn 29, Issue 12, 2008, Pages 1940-1949

  Lee, Yeonju ^a   Schmid, Marian J ^a   Marx, David B ^b   Beatty, Mark W ^a   Cullen, Diane M ^c   Collins, Melissa E ^b   Reinhardt, Richard A ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^c CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bone formation; In vivo; Local delivery; Long term; Mechanical tests; Simvastatin

Indexed keywords

BONE; FRACTURE; HISTOLOGY; LACTIC ACID; ROBUST CONTROL; STIFFNESS;

BONE FORMATION; LOCAL DELIVERY; MECHANICAL TESTS; SIMVASTATIN;

PROTEINS;

CHOLESTEROL; POLYLACTIC ACID; SIMVASTATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE GROWTH; DRUG DELIVERY SYSTEM; FORCE; FRACTURE; HISTOLOGY; IMPLANTATION; IN VIVO STUDY; MANDIBLE; MECHANICS; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; RAT; RIGIDITY; SWELLING;

ANIMALS; ANTICHOLESTEREMIC AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; FEMALE; INJECTIONS; MANDIBLE; OSTEOGENESIS; RATS; RATS, SPRAGUE-DAWLEY; SIMVASTATIN;

ANIMALIA; RATTUS;

EID: 39649089565     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2007.12.045     Document Type: Article

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