Insights into the early dissolution events of amlodipine using UV imaging and Raman spectroscopy

Molecular Pharmaceutics

Volumn 8, Issue 4, 2011, Pages 1372-1380

  Boetker, Johan P ^a   Savolainen, Marja ^a   Koradia, Vishal ^a,b   Tian, Fang ^a   Rades, Thomas ^c   Müllertz, Anette ^a   Cornett, Claus ^a   Rantanen, Jukka ^a   Østergaard, Jesper ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NOVARTIS PHARMA AG   (Switzerland)

^c UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

amorphous; crystalline; dissolution; Raman spectroscopy; solid state transformation; UV imaging

Indexed keywords

AMLODIPINE; AMLODIPINE BESYLATE;

ARTICLE; CRYSTAL STRUCTURE; DISSOLUTION; FEASIBILITY STUDY; PRIORITY JOURNAL; RAMAN SPECTROMETRY; ULTRAVIOLET RADIATION;

AMLODIPINE; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; SOLUBILITY; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTRUM ANALYSIS, RAMAN; THERMOGRAVIMETRY;

EID: 79961035430     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200205z     Document Type: Article

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