Chemical imaging of oral solid dosage forms and changes upon dissolution using coherent anti-stokes raman scattering microscopy

Analytical Chemistry

Volumn 81, Issue 6, 2009, Pages 2085-2091

  Windbergs, Maike ^a,b   Jurna, Martin ^c   Offerhaus, Herman L ^c   Herek, Jennifer L ^c   Kleinebudde, Peter ^a   Strachan, Clare J ^b,d  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF TWENTE   (Netherlands)

^d UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE INGREDIENTS; ANHYDRATE; CHEMICAL IMAGING; COHERENT ANTI-STOKES RAMAN SCATTERING MICROSCOPIES; CONCENTRATION OF; DISSOLUTION BEHAVIORS; DISSOLUTION TESTING; DOSAGE FORMS; DRUG RELEASE; EXTRUDATES; MATRIXES; MODEL DRUGS; ORAL DOSAGES; PHARMACEUTICAL DOSAGE FORMS; REAL TIME; SOLID DOSAGE FORMS; SOLID-STATE PROPERTIES; SOLID-STATE TRANSFORMATIONS; SPATIAL RESOLUTIONS; SUSTAINED RELEASE;

DRUG DOSAGE; DRUG PRODUCTS; POLYMORPHISM; RAMAN SCATTERING; RAMAN SPECTROSCOPY;

DISSOLUTION;

LIPID; THEOPHYLLINE;

ARTICLE; COHERENT ANTI STOKES RAMAN SCATTERING MICROSCOPY; CONTROLLED STUDY; DRUG DOSAGE FORM; DRUG RELEASE; DRUG SOLUBILITY; MICROSCOPY; PHYSICAL CHEMISTRY; RAMAN SPECTROMETRY; SUSTAINED RELEASE FORMULATION;

ADMINISTRATION, ORAL; CHEMISTRY, PHARMACEUTICAL; DOSAGE FORMS; LIPIDS; MICROSCOPY; SOLUBILITY; SPECTRUM ANALYSIS, RAMAN; THEOPHYLLINE; TIME FACTORS;

EID: 64649103561     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac8020856     Document Type: Article

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