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Volumn 14, Issue 8, 2011, Pages 648-657

Seeing the light: Luminescent reporter gene assays

Author keywords

Firefly; Luciferase Renilla; Luciferin; Promoter; Reporter gene assay (RGA)

Indexed keywords

LUCIFERASE;

EID: 79961034737     PISSN: 13862073     EISSN: 18755402     Source Type: Journal    
DOI: 10.2174/138620711796504389     Document Type: Review
Times cited : (28)

References (51)
  • 1
    • 0347511689 scopus 로고    scopus 로고
    • Fluorescence readouts in HTS: No gain without pain?
    • DOI 10.1016/S1359-6446(03)02895-2, PII S1359644603028952
    • Gribbon, P.; Sewing, A. Fluorescence readouts in HTS: no gain without pain? Drug Discov. Today, 2003, 8 (22), 1035-1043. (Pubitemid 38018810)
    • (2003) Drug Discovery Today , vol.8 , Issue.22 , pp. 1035-1043
    • Gribbon, P.1    Sewing, A.2
  • 2
    • 0023548002 scopus 로고
    • Identification of a peroxisomal targeting signal at the carboxy terminus of firefly luciferase
    • Gould, S. G.; Keller, G. A.; Subramani, S. Identification of a peroxisomal targeting signal at the carboxy terminus of firefly luciferase. Journal of Cell Biology 1987, 105 (6 Pt 2), 2923-2931. (Pubitemid 18043870)
    • (1987) Journal of Cell Biology , vol.105 , Issue.6 , pp. 2923-2931
    • Gould, S.J.1    Keller, G.-A.2    Subramani, S.3
  • 4
    • 0033822731 scopus 로고    scopus 로고
    • Development of a destabilized firefly luciferase enzyme for measurement of gene expression
    • Leclerc, G. M.; Boockfor, F. R.; Faught, W. J.; Frawley, L. S. Development of a destabilized firefly luciferase enzyme for measurement of gene expression. Biotechniques, 2000, 29 (3), 590-591.
    • (2000) Biotechniques , vol.29 , pp. 590-591
    • Leclerc, G.M.1    Boockfor, F.R.2    Faught, W.J.3    Frawley, L.S.4
  • 5
    • 25644461156 scopus 로고    scopus 로고
    • Comparison of the responsiveness of the pGL3 and pGL4 luciferase reporter vectors to steroid hormones
    • Dougherty, D. C.; Sanders, M. M. Comparison of the responsiveness of the pGL3 and pGL4 luciferase reporter vectors to steroid hormones. Biotechniques, 2005, 39 (2), 203-207.
    • (2005) Biotechniques , vol.39 , Issue.2 , pp. 203-207
    • Dougherty, D.C.1    Sanders, M.M.2
  • 7
    • 14044250981 scopus 로고    scopus 로고
    • Codon-optimized gaussia luciferase cDNA for mammalian gene expression in culture and in vivo
    • DOI 10.1016/j.ymthe.2004.10.016, PII S1525001604015084
    • Tannous BA, K. D., Fernandez JL, Weissleder R, Breakefield XO. Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Molecular Therapy 2005, 11 (3),435-443. (Pubitemid 40277320)
    • (2005) Molecular Therapy , vol.11 , Issue.3 , pp. 435-443
    • Tannous, B.A.1    Kim, D.-E.2    Fernandez, J.L.3    Weissleder, R.4    Breakefield, X.O.5
  • 8
    • 0037098939 scopus 로고    scopus 로고
    • Bacterial expression of in vivo-biotinylated aequorin for direct application to bioluminometric hybridization assays
    • DOI 10.1006/abio.2002.5724
    • Verhaegen M, Christopoulos, T. K. Bacterial expression of in vivobiotinylated aequorin for direct application to bioluminometric hybridization assays. Anal. Biochem., 2002, 306 (2), 314-322. (Pubitemid 34791502)
    • (2002) Analytical Biochemistry , vol.306 , Issue.2 , pp. 314-322
    • Verhaegen, M.1    Christopoulos, T.K.2
  • 9
    • 67650389231 scopus 로고    scopus 로고
    • S. P. Use of aequorin for G protein-coupled receptor hit identification and compound profiling
    • Brough SJ, S. P. Use of aequorin for G protein-coupled receptor hit identification and compound profiling. Methods Mol. Biol., 2009,181-198
    • (2009) Methods Mol. Biol. , pp. 181-198
    • Brough, S.J.1
  • 10
    • 77957228720 scopus 로고    scopus 로고
    • Application of new semisynthetic aequorins with long half-decay time of luminescence to G-protein-coupled receptor assay
    • Inouye, S.; Iimori, R.; Sahara, Y.; Hisada, S.; Hosoya, T. Application of new semisynthetic aequorins with long half-decay time of luminescence to G-protein-coupled receptor assay. Anal. Biochem., 2010.
    • (2010) Anal. Biochem.
    • Inouye, S.1    Iimori, R.2    Sahara, Y.3    Hisada, S.4    Hosoya, T.5
  • 11
    • 0023790164 scopus 로고
    • Application of an ATP-bioluminescence assay in human tumor chemosensitivity testing
    • Sevin, B. U.; Peng, Z. L.; Perras, J. P.; Ganjei, P.; Penalver, M.; Averette, H. E. Application of an ATP-bioluminescence assay in human tumor chemosensitivity testing. Gynecol. Oncol., 1988, 31 (1), 191-204.
    • (1988) Gynecol. Oncol. , vol.31 , Issue.1 , pp. 191-204
    • Sevin, B.U.1    Peng, Z.L.2    Perras, J.P.3    Ganjei, P.4    Penalver, M.5    Averette, H.E.6
  • 12
    • 0042476427 scopus 로고    scopus 로고
    • Locating a protein-protein interaction in living cells via split Renilla luciferase complementation
    • DOI 10.1021/ac0300800
    • Kaihara, A.; Kawai, Y.; Sato, M.; Ozawa, T.; Umezawa, Y. Locating a protein-protein interaction in living cells via split Renilla luciferase complementation. Anal. Chem., 2003, 75 (16),4176-4181 (Pubitemid 37012551)
    • (2003) Analytical Chemistry , vol.75 , Issue.16 , pp. 4176-4181
    • Kaihara, A.1    Kawai, Y.2    Sato, M.3    Ozawa, T.4    Umezawa, Y.5
  • 13
    • 0027503849 scopus 로고
    • An easily synthesized, photolyzable luciferase substrate for in vivo luciferase activity measurement
    • Yang, J.; Thomason, D. B. An easily synthesized, photolyzable luciferase substrate for in vivo luciferase activity measurement. Biotechniques, 1993, 15 (5), 848-850. (Pubitemid 23333278)
    • (1993) BioTechniques , vol.15 , Issue.5 , pp. 848-850
    • Yang, J.1    Thomason, D.B.2
  • 14
    • 25144447381 scopus 로고    scopus 로고
    • Bioluminescent imaging of TRAIL-induced apoptosis through detection of caspase activation following cleavage of DEVD-aminoluciferin
    • Liu JJ, W. W., Dicker DT, El-Deiry WS. Bioluminescent imaging of TRAIL-induced apoptosis through detection of caspase activation following cleavage of DEVD-aminoluciferin. Cancer Biol. Ther., 2005, 4, 885-892.
    • (2005) Cancer Biol. Ther. , vol.4 , pp. 885-892
    • Liu, J.J.1    Dicker, W.W.D.T.2    El-Deiry, W.S.3
  • 16
    • 67650792478 scopus 로고    scopus 로고
    • Evaluation of luciferin-isopropyl acetal as a CYP3A4 substrate for human hepatocytes: Effects of organic solvents, cytochrome P450 (P450) inhibitors, and P450 inducers
    • Li, A. Evaluation of luciferin-isopropyl acetal as a CYP3A4 substrate for human hepatocytes: effects of organic solvents, cytochrome P450 (P450) inhibitors, and P450 inducers. Drug Metab. Dispos., 2009, 37 (8), 1598-1603.
    • (2009) Drug Metab. Dispos. , vol.37 , Issue.8 , pp. 1598-1603
    • Li, A.1
  • 17
    • 41549124086 scopus 로고    scopus 로고
    • The BRET technology and its application to screening assays
    • Bacart J, C. C., Jockers R, Bach S, Couturier C. The BRET technology and its application to screening assays. Biotechnol J.,3 (3), 311-324.
    • Biotechnol J. , vol.3 , Issue.3 , pp. 311-324
    • Bacart J, C.C.1    Jockers, R.2    Bach, S.3    Couturier, C.4
  • 19
    • 0023124097 scopus 로고
    • Firefly luciferase gene: Structure and expression in mammalian cells
    • de Wet JR, W. K., DeLuca M, Helinski DR, Subramani S. Firefly luciferase gene: structure and expression in mammalian cells. Mol. Cell. Biol., 1987, 7 (2), 725-737. (Pubitemid 17004537)
    • (1987) Molecular and Cellular Biology , vol.7 , Issue.2 , pp. 725-737
    • De Wet, J.R.1    Wood, K.V.2    DeLuca, M.3
  • 20
    • 0000229438 scopus 로고
    • Functional regions of the cauliflower mosaic virus 35S RNA promoter determined by use of the firefly luciferase gene as a reporter of promoter activity
    • Ow DW, J. J., Howell SH. Functional regions of the cauliflower mosaic virus 35S RNA promoter determined by use of the firefly luciferase gene as a reporter of promoter activity. Proc. Natl Acad. Sci. USA, 1987, 84 (14), 4870-4874.
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , Issue.14 , pp. 4870-4874
    • Ow, D.W.1    Howell, J.J.S.H.2
  • 21
    • 0029775175 scopus 로고    scopus 로고
    • Role of TATA box sequence and orientation in determining RNA polymerase II/III transcription specificity
    • Wang, Y.; Jensen, R. C.; Stumph, W. E. Role of TATA box sequence and orientation in determining RNA polymerase II/III transcription specificity. Nucleic Acids Res., 1996, 24 (15), 3100-3106 (Pubitemid 26289606)
    • (1996) Nucleic Acids Research , vol.24 , Issue.15 , pp. 3100-3106
    • Wang, Y.1    Jensen, R.C.2    Stumph, W.E.3
  • 23
    • 0028042492 scopus 로고
    • On beyond classic RACE (rapid amplification of cDNA ends)
    • Frohman, M. A., On beyond classic RACE (rapid amplification of cDNA ends). PCR Meth. Appl., 1994, 4 (1), S40-58. (Pubitemid 2137064)
    • (1994) Genome Research , vol.4 , Issue.1
    • Frohman, M.A.1
  • 24
    • 74949138148 scopus 로고    scopus 로고
    • Identification of alternative transcripts using rapid amplification of cDNA ends (RACE)
    • Yeku, O.; Scotto-Lavino, E.; Frohman, M. A. Identification of alternative transcripts using rapid amplification of cDNA ends (RACE). Methods Mol. Biol., 2009, 590, 279-94.
    • (2009) Methods Mol. Biol. , vol.590 , pp. 279-294
    • Yeku, O.1    Scotto-Lavino, E.2    Frohman, M.A.3
  • 26
    • 34250359062 scopus 로고    scopus 로고
    • ENCODE: More genomic empowerment
    • DOI 10.1101/gr.6534207
    • Weinstock, G. M. ENCODE: more genomic empowerment. Genome Research, 2007, 17 (6), 667-668. (Pubitemid 46919704)
    • (2007) Genome Research , vol.17 , Issue.6 , pp. 667-668
    • Weinstock, G.M.1
  • 27
    • 34250305146 scopus 로고    scopus 로고
    • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
    • DOI 10.1038/nature05874, PII NATURE05874
    • Consortium, E. P.; Birney, E.; Stamatoyannopoulos, J. A.; Dutta, A.; Guigo, R.; Gingeras, T. R.; Margulies, E. H.; Weng, Z.; Snyder, M.; Dermitzakis, E. T.; Thurman, R. E.; Kuehn, M. S.; Taylor, C. M.; Neph, S.; Koch, C. M.; Asthana, S.; Malhotra, A.; Adzhubei, I.; Greenbaum, J. A.; Andrews, R. M.; Flicek, P.; Boyle, P. J.; Cao, H.; Carter, N. P.; Clelland, G. K.; Davis, S.; Day, N.; Dhami, P.; Dillon, S. C.; Dorschner, M. O.; Fiegler, H.; Giresi, P. G.; Goldy, J.; Hawrylycz, M.; Haydock, A.; Humbert, R.; James, K. D.; Johnson, B. E.; Johnson, E. M.; Frum, T. T.; Rosenzweig, E. R.; Karnani, N.; Lee, K.; Lefebvre, G. C.; Navas, P. A.; Neri, F.; Parker, S. C.; Sabo, P. J.; Sandstrom, R.; Shafer, A.; Vetrie, D.; Weaver, M.; Wilcox, S.; Yu, M.; Collins, F. S.; Dekker, J.; Lieb, J. D.; Tullius, T. D.; Crawford, G. E.; Sunyaev, S.; Noble, W. S.; Dunham, I.; Denoeud, F.; Reymond, A.; Kapranov, P.; Rozowsky, J.; Zheng, D.; Castelo, R.; Frankish, A.; Harrow, J.; Ghosh, S.; Sandelin, A.; Hofacker, I. L.; Baertsch, R.; Keefe, D.; Dike, S.; Cheng, J.; Hirsch, H. A.; Sekinger, E. A.; Lagarde, J.; Abril, J. F.; Shahab, A.; Flamm, C.; Fried, C.; Hackermuller, J.; Hertel, J.; Lindemeyer, M.; Missal, K.; Tanzer, A.; Washietl, S.; Korbel, J.; Emanuelsson, O.; Pedersen, J. S.; Holroyd, N.; Taylor, R.; Swarbreck, D.; Matthews, N.; Dickson, M. C.; Thomas, D. J.; Weirauch, M. T.; Gilbert, J.; Drenkow, J.; Bell, I.; Zhao, X.; Srinivasan, K. G.; Sung, W. K.; Ooi, H. S.; Chiu, K. P.; Foissac, S.; Alioto, T.; Brent, M.; Pachter, L.; Tress, M. L.; Valencia, A.; Choo, S. W.; Choo, C. Y.; Ucla, C.; Manzano, C.; Wyss, C.; Cheung, E.; Clark, T. G.; Brown, J. B.; Ganesh, M.; Patel, S.; Tammana, H.; Chrast, J.; Henrichsen, C. N.; Kai, C.; Kawai, J.; Nagalakshmi, U.; Wu, J.; Lian, Z.; Lian, J.; Newburger, P.; Zhang, X.; Bickel, P.; Mattick, J. S.; Carninci, P.; Hayashizaki, Y.; Weissman, S.; Hubbard, T.; Myers, R. M.; Rogers, J.; Stadler, P. F.; Lowe, T. M.; Wei, C. L.; Ruan, Y.; Struhl, K.; Gerstein, M.; Antonarakis, S. E.; Fu, Y.; Green, E. D.; Karaoz, U.; Siepel, A.; Taylor, J.; Liefer, L. A.; Wetterstrand, K. A.; Good, P. J.; Feingold, E. A.; Guyer, M. S.; Cooper, G. M.; Asimenos, G.; Dewey, C. N.; Hou, M.; Nikolaev, S.; Montoya-Burgos, J. I.; Loytynoja, A.; Whelan, S.; Pardi, F.; Massingham, T.; Huang, H.; Zhang, N. R.; Holmes, I.; Mullikin, J. C.; Ureta-Vidal, A.; Paten, B.; Seringhaus, M.; Church, D.; Rosenbloom, K.; Kent, W. J.; Stone, E. A.; Program, N. C. S.; Baylor College of Medicine Human Genome Sequencing, C.; Washington University Genome Sequencing, C.; Broad, I.; Children's Hospital Oakland Research, I.; Batzoglou, S.; Goldman, N.; Hardison, R. C.; Haussler, D.; Miller, W.; Sidow, A.; Trinklein, N. D.; Zhang, Z. D.; Barrera, L.; Stuart, R.; King, D. C.; Ameur, A.; Enroth, S.; Bieda, M. C.; Kim, J.; Bhinge, A. A.; Jiang, N.; Liu, J.; Yao, F.; Vega, V. B.; Lee, C. W.; Ng, P.; Shahab, A.; Yang, A.; Moqtaderi, Z.; Zhu, Z.; Xu, X.; Squazzo, S.; Oberley, M. J.; Inman, D.; Singer, M. A.; Richmond, T. A.; Munn, K. J.; Rada-Iglesias, A.; Wallerman, O.; Komorowski, J.; Fowler, J. C.; Couttet, P.; Bruce, A. W.; Dovey, O. M.; Ellis, P. D.; Langford, C. F.; Nix, D. A.; Euskirchen, G.; Hartman, S.; Urban, A. E.; Kraus, P.; Van Calcar, S.; Heintzman, N.; Kim, T. H.; Wang, K.; Qu, C.; Hon, G.; Luna, R.; Glass, C. K.; Rosenfeld, M. G.; Aldred, S. F.; Cooper, S. J.; Halees, A.; Lin, J. M.; Shulha, H. P.; Zhang, X.; Xu, M.; Haidar, J. N.; Yu, Y.; Ruan, Y.; Iyer, V. R.; Green, R. D.; Wadelius, C.; Farnham, P. J.; Ren, B.; Harte, R. A.; Hinrichs, A. S.; Trumbower, H.; Clawson, H.; Hillman-Jackson, J.; Zweig, A. S.; Smith, K.; Thakkapallayil, A.; Barber, G.; Kuhn, R. M.; Karolchik, D.; Armengol, L.; Bird, C. P.; de Bakker, P. I.; Kern, A. D.; Lopez- Bigas, N.; Martin, J. D.; Stranger, B. E.; Woodroffe, A.; Davydov, E.; Dimas, A.; Eyras, E.; Hallgrimsdottir, I. B.; Huppert, J.; Zody, M. C.; Abecasis, G. R.; Estivill, X.; Bouffard, G. G.; Guan, X.; Hansen, N. F.; Idol, J. R.; Maduro, V. V.; Maskeri, B.; McDowell, J. C.; Park, M.; Thomas, P. J.; Young, A. C.; Blakesley, R. W.; Muzny, D. M.; Sodergren, E.; Wheeler, D. A.; Worley, K. C.; Jiang, H.; Weinstock, G. M.; Gibbs, R. A.; Graves, T.; Fulton, R.; Mardis, E. R.; Wilson, R. K.; Clamp, M.; Cuff, J.; Gnerre, S.; Jaffe, D. B.; Chang, J. L.; Lindblad-Toh, K.; Lander, E. S.; Koriabine, M.; Nefedov, M.; Osoegawa, K.; Yoshinaga, Y.; Zhu, B.; de Jong, P. J. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 2007, 447 (7146), 799-816. (Pubitemid 46920138)
    • (2007) Nature , vol.447 , Issue.7146 , pp. 799-816
    • Birney, E.1    Stamatoyannopoulos, J.A.2    Dutta, A.3    Guigo, R.4    Gingeras, T.R.5    Margulies, E.H.6    Weng, Z.7    Snyder, M.8    Dermitzakis, E.T.9    Thurman, R.E.10    Kuehn, M.S.11    Taylor, C.M.12    Neph, S.13    Koch, C.M.14    Asthana, S.15    Malhotra, A.16    Adzhubei, I.17    Greenbaum, J.A.18    Andrews, R.M.19    Flicek, P.20    more..
  • 29
    • 0035167598 scopus 로고    scopus 로고
    • Cell density and phosphorylation control the subcellular localization of adenomatous polyposis coli protein
    • DOI 10.1128/MCB.21.23.8143-8156.2001
    • Zhang, F.; White, R. L.; Neufeld, K. L. Cell density and phosphorylation control the subcellular localization of adenomatous polyposis coli protein. Mol. Cell Biol., 2001, 21 (23), 8143-8156. (Pubitemid 33051803)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.23 , pp. 8143-8156
    • Zhang, F.1    White, R.L.2    Neufeld, K.L.3
  • 30
    • 13944277097 scopus 로고    scopus 로고
    • Angiogenin is translocated to the nucleus of HeLa cells and is involved in ribosomal RNA transcription and cell proliferation
    • DOI 10.1158/0008-5472.CAN-04-2058
    • Tsuji, T.; Sun, Y.; Kishimoto, K.; Olson, K. A.; Liu, S.; Hirukawa, S.; Hu, G. F. Angiogenin is translocated to the nucleus of HeLa cells and is involved in ribosomal RNA transcription and cell proliferation. Cancer Res., 2005, 65 (4), 1352-1360. (Pubitemid 40270162)
    • (2005) Cancer Research , vol.65 , Issue.4 , pp. 1352-1360
    • Tsuji, T.1    Sun, Y.2    Kishimoto, K.3    Olson, K.A.4    Liu, S.5    Hirukawa, S.6    Hu, G.-F.7
  • 31
    • 27944432167 scopus 로고    scopus 로고
    • A set of multicolored Photinus pyralis luciferase mutants for in vivo bioluminescence applications
    • DOI 10.1093/protein/gzi066
    • Shapiro, E.; Lu, C.; Baneyx, F. A set of multicolored Photinus pyralis luciferase mutants for in vivo bioluminescence applications. Protein Eng. Des. Sel., 2005, 18 (12), 581-587. (Pubitemid 41668824)
    • (2005) Protein Engineering, Design and Selection , vol.18 , Issue.12 , pp. 581-587
    • Shapiro, E.1    Lu, C.2    Baneyx, F.3
  • 33
    • 77953689492 scopus 로고    scopus 로고
    • Illuminating insights into firefly luciferase and other bioluminescent reporters used in chemical biology
    • Thorne, N.; Inglese, J.; Auld, D. S. Illuminating insights into firefly luciferase and other bioluminescent reporters used in chemical biology. Chem Biol 2010, 5(6), 646-657.
    • Chem Biol 2010 , vol.5 , Issue.6 , pp. 646-657
    • Thorne, N.1    Inglese, J.2    Auld, D.S.3
  • 34
    • 33744511527 scopus 로고    scopus 로고
    • Perfusion-culture-based secreted bioluminescence reporter assay in living cells
    • DOI 10.1016/j.ab.2006.03.031, PII S0003269706002119
    • Yamagishi, K.; Enomoto, T.; Ohmiya, Y. Perfusion-culture-based secreted bioluminescence reporter assay in living cells. Analyt., Biochem., 2006, 354 (1), 15-21. (Pubitemid 43816382)
    • (2006) Analytical Biochemistry , vol.354 , Issue.1 , pp. 15-21
    • Yamagishi, K.1    Enomoto, T.2    Ohmiya, Y.3
  • 36
    • 49449106910 scopus 로고    scopus 로고
    • False positives in a reporter gene assay: Identification and synthesis of substituted N-pyridin-2-ylbenzamides as competitive inhibitors of firefly luciferase
    • Heitman, L.H.; van Veldhoven, J.P.D.; Zweemer, A.M.; Ye, K.; Brussee, J.; IJzerman, A.P. False positives in a reporter gene assay: identification and synthesis of substituted N-pyridin-2- ylbenzamides as competitive inhibitors of firefly luciferase. J. Med. Chem., 2008, 51 (15), 4724-4729.
    • (2008) J. Med. Chem. , vol.51 , Issue.15 , pp. 4724-4729
    • Heitman, L.H.1    Van Veldhoven, J.P.D.2    Zweemer, A.M.3    Ye, K.4    Brussee, J.5    Ijzerman, A.P.6
  • 37
    • 62549134976 scopus 로고    scopus 로고
    • Mechanism of PTC124 activity in cell-based luciferase assays of nonsense codon suppression
    • Auld, D. S.; Thorne, N.; Maguire, W. F.; Inglese, J. Mechanism of PTC124 activity in cell-based luciferase assays of nonsense codon suppression. Proc. Natl. Acad. Sci. USA, 2009, 106 (9), 3585-3590.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , Issue.9 , pp. 3585-3590
    • Auld, D.S.1    Thorne, N.2    Maguire, W.F.3    Inglese, J.4
  • 38
    • 0025823443 scopus 로고
    • Modulation of firefly luciferase stability and impact on studies of gene regulation
    • Thompson, J. F.; Hayes, L. S.; Lloyd, D. B. Modulation of firefly luciferase stability and impact on studies of gene regulation. Gene, 1991, 103 (2), 171-177.
    • (1991) Gene , vol.103 , Issue.2 , pp. 171-177
    • Thompson, J.F.1    Hayes, L.S.2    Lloyd, D.B.3
  • 42
    • 77955708471 scopus 로고    scopus 로고
    • MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2
    • Ding, L.; Xu, Y.; Zhang, W.; Deng, Y.; Si, M.; Du, Y.; Yao, H.; Liu, X.; Ke, Y.; Si, J.; Zhou, T., MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2. Cell Res., 2010, 20 (7), 784-793.
    • (2010) Cell Res , vol.20 , Issue.7 , pp. 784-793
    • Ding, L.1    Xu, Y.2    Zhang, W.3    Deng, Y.4    Si, M.5    Du, Y.6    Yao, H.7    Liu, X.8    Ke, Y.9    Si, J.10    Zhou, T.11
  • 44
    • 2542447230 scopus 로고    scopus 로고
    • Techniques: Reporter mice - A new way to look at drug action
    • DOI 10.1016/j.tips.2004.04.007, PII S0165614704001191
    • Maggi, A.; Ottobrini, L.; Biserni, A.; Lucignani, G.; Ciana, P. Techniques: reporter mice - a new way to look at drug action. Trends Pharmacol. Sci., 2004, 25 (6), 337-342. (Pubitemid 38692427)
    • (2004) Trends in Pharmacological Sciences , vol.25 , Issue.6 , pp. 337-342
    • Maggi, A.1    Ottobrini, L.2    Biserni, A.3    Lucignani, G.4    Ciana, P.5
  • 45
    • 77952254962 scopus 로고    scopus 로고
    • Bioluminescence imaging of reporter mice for studies of infection and inflammation
    • Luker, K. E.; Luker, G. D., Bioluminescence imaging of reporter mice for studies of infection and inflammation. Antiviral. Res., 2010, 86 (1), 93-100.
    • (2010) Antiviral. Res. , vol.86 , Issue.1 , pp. 93-100
    • Luker, K.E.1    Luker, G.D.2
  • 47
    • 4344658402 scopus 로고    scopus 로고
    • Induction and regulation of IFNs during viral infections
    • DOI 10.1089/1079990041689665
    • Malmgaard, L., Induction and regulation of IFNs during viral infections. J. Interferon Cytokine Res., 2004, 24 (8), 439-454. (Pubitemid 39120592)
    • (2004) Journal of Interferon and Cytokine Research , vol.24 , Issue.8 , pp. 439-454
    • Malmgaard, L.1
  • 48
    • 33646064444 scopus 로고    scopus 로고
    • Transgenic reporter mouse for bioluminescence imaging of herpes simplex virus 1 infection in living mice
    • Luker, K. E.; Schultz, T.; Romine, J.; Leib, D. A.; Luker, G. D. Transgenic reporter mouse for bioluminescence imaging of herpes simplex virus 1 infection in living mice. Virology 2006, 347 (2), 286-295.
    • (2006) Virology , vol.347 , Issue.2 , pp. 286-295
    • Luker, K.E.1    Schultz, T.2    Romine, J.3    Leib, D.A.4    Luker, G.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.