Microfibrous carriers for cell culture: A comparative study

Biotechnology Progress

Volumn 27, Issue 4, 2011, Pages 1126-1136

  Wen, Yuan ^a   Yang, Shang Tian ^a,b  

^a Ohio State University   (United States)

^b Life Technologies Corp   (United States)

Author keywords

Adhesion; Cell adsorption; CHO; Fibrous carrier; Microcarrier culture; Polyethylene terephthalate

Indexed keywords

AGITATED BIOREACTORS; AGITATION RATES; CELL ADSORPTION; CELL ATTACHMENTS; CHINESE HAMSTER OVARY CELLS; CHO; COMPARATIVE STUDIES; CULTURING CELLS; FIBROUS CARRIER; HIGH-DENSITY; LARGE SURFACE AREA; LOWER COST; MACROPOROUS; MICROCARRIER CULTURE; MICROCARRIERS; MICROFIBROUS; MICROFIBROUS CARRIERS; MONOCLONAL ANTIBODY PRODUCTION; NON-WOVEN; THREE DIMENSIONAL SPACE;

ADSORPTION; CELLS; GROWTH KINETICS; MONOCLONAL ANTIBODIES; POLYESTERS; POLYETHYLENE TEREPHTHALATES; POLYETHYLENES;

CELL CULTURE;

POLYETHYLENE TEREPHTHALATE;

ANIMAL; ARTICLE; CELL ADHESION; CHEMISTRY; CHO CELL; CULTURE TECHNIQUE; HAMSTER; METHODOLOGY; PHYSIOLOGY;

ANIMALS; CELL ADHESION; CELL CULTURE TECHNIQUES; CHO CELLS; CRICETINAE; POLYETHYLENE TEREPHTHALATES;

CRICETULUS GRISEUS;

EID: 79961022336     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.625     Document Type: Article

References (36)

1. Liu CC, Lian WC, Butler M, Wu SC. High immunogenic enterovirus 71 strain and its production using serum-free microcarrier Vero cell culture. Vaccine. 2007; 25: 19-24.
2. Rourou S, van der Ark A, van der Velden T, Kallel H. A microcarrier cell culture process for propagating rabies virus in Vero cells grown in a stirred bioreactor under fully animal component free conditions. Vaccine. 2007; 25: 3879-3889.
3. Botchwey EA, Pollack SR, Levine EM, Laurencin CT. Bone tissue engineering in a rotating bioreactor using a microcarrier matrix system. J Biomed Mater Res. 2001; 55: 242-253.
4. Huss FR, Junker JP, Johnson H, Kratz G. Macroporous gelatine spheres as culture substrate, transplantation vehicle, and biodegradable scaffold for guided regeneration of soft tissues. In vivo study in nude mice. J Plast Reconstr Aesthet Surg. 2007; 60: 543-555.
5. Malda J, Frondoza CG. Microcarriers in the engineering of cartilage and bone. Trends Biotechnol. 2006; 24: 299-304.
6. Tatard VM, Venier-Julienne MC, Saulnier P, Prechter E, Benoit JP, Menei P, Montero-Menei CN. Pharmacologically active microcarriers: a tool for cell therapy. Biomaterials. 2005; 26: 3727-3737.
7. Lock LT, Tzanakakis ES. Expansion and differentiation of human embryonic stem cells to endoderm progeny in a microcarrier stirred-suspension culture. Tissue Eng Part A. 2009; 15: 2051-2063.
8. Abranches E, Bekman E, Henrique D, Cabral JM. Expansion of mouse embryonic stem cells on microcarriers. Biotechnol Bioeng. 2007; 96: 1211-1221.
9. Phillips BW, Horne R, Lay TS, Rust WL, Teck TT, Crook JM. Attachment and growth of human embryonic stem cells on microcarriers. J Biotechnol. 2008; 138: 24-32.
10. Hong Y, Gao C, Xie Y, Gong Y, Shen J. Collagen-coated polylactide microspheres as chondrocyte microcarriers. Biomaterials. 2005; 26: 6305-6313.
11. Cahn F. Biomaterials aspects of porous microcarriers for animal cell culture. Trends Biotechnol. 1990; 8: 131-136.
12. Gebb C, Clark JM, Hirtenstein MD, Lindgren GE, Lundgren BJ, Lindskog U, Vretblad P. Alternative surfaces for microcarrier culture of animal cells. Adv Exp Med Biol. 1984; 172: 151-167.
13. Lao L, Tan H, Wang Y, Gao C. Chitosan modified poly(L-lactide) microspheres as cell microcarriers for cartilage tissue engineering. Colloids Surf B Biointerfaces. 2008; 66: 218-225.
14. Matsushita T, Ketayama M, Kamihata K, Funatsu K. Anchorage-dependent mammalian cell culture using polyurethane foam as a new substratum for cell attachment. Appl Microbiol Biotechnol. 1990; 33: 287-290.
15. Wu TJ, Huang HH, Hsu YM, Lyu SR, Wang YJ. A novel method of encapsulating and cultivating adherent mammalian cells within collagen microcarriers. Biotechnol Bioeng. 2007; 98: 578-585.
16. Sugiura S, Oda T, Izumida Y, Aoyagi Y, Satake M, Ochiai A, Ohkohchi N, Nakajima M. Size control of calcium alginate beads containing living cells using micro-nozzle array. Biomaterials. 2005; 26: 3327-3331.
17. Chen XG, Liu CS, Liu CG, Meng XH, Lee CM, Park HJ. Preparation and biocompatibility of chitosan microcarriers as biomaterial. Biochem Eng J. 2006; 27: 269-274.
18. Li K, Wang Y, Miao Z, Xu D, Tang Y, Feng M. Chitosan/gelatin composite microcarrier for hepatocyte culture. Biotechnol Lett. 2004; 26: 879-883.
19. Wu C, Pan J, Bao Z, Yu Y. Fabrication and characterization of chitosan microcarrier for hepatocyte culture. J Mater Sci Mater Med. 2007; 18: 2211-2214.
20. Keese CR, Giaever I. Cell growth on liquid microcarriers. Science. 1983; 219: 1448-1449.
21. Li Y, Ma T, Yang ST, Kniss DA. Thermal compression and characterization of three-dimensional nonwoven PET matrices as tissue engineering scaffolds. Biomaterials. 2001; 22: 609-618.
22. Luo J, Yang ST. Effects of three-dimensional culturing in a fibrous matrix on cell cycle, apoptosis, and MAb production by hybridoma cells. Biotechnol Prog. 2004; 20: 306-315.
23. Wen Y, Zhang X, Yang ST. Microplate-reader compatible perfusion microbioreactor array for modular tissue culture and cytotoxicity assays. Biotechnol Prog. 2010; 26: 1135-1144.
24. Micheletti M, Barrett T, Doig SD, Baganz F, Levy MS, Woodley JM, Lye GJ. Fluid mixing in shaken bioreactors: implications for scale-up predictions from microliter-scale microbial and mammalian cell cultures. Chem Eng Sci. 2006; 61: 2939-2949.
25. Barrett TA, Wu A, Zhang H, Levy MS, Lye GJ. Microwell engineering characterization for mammalian cell culture process development. Biotechnol Bioeng. 2010; 105: 260-275.
26. Zhang H, Lamping SR, Pickering SCR, Lye GJ, Shamlou PA. Engineering characterization of a single well from 24-well and 96-well microtitre plates. Biochem Eng J. 2008; 40: 138-149.
27. Ouyang A, Yang ST. Effects of mixing intensity on cell seeding and proliferation in three-dimensional fibrous matrices. Biotechnol Bioeng. 2007; 96: 371-380.
28. Ng R, Gurm JS, Yang ST. Centrifugal seeding of mammalian cells in nonwoven fibrous matrices. Biotechnol Prog. 2010; 26: 239-245.
29. Zhang X, Yang ST. High-throughput 3-D cell-based proliferation and cytotoxicity assays for drug screening and bioprocess development. J Biotechnol. 2011; 151: 186-193.
30. Schop D, Janssen FW, Borgart E, de Bruijn JD, van Dijkhuizen-Radersma R. Expansion of mesenchymal stem cells using a microcarrier-based cultivation system: growth and metabolism. J Tissue Eng Regen Med. 2008; 2: 126-135.
31. Wong HL, Wang MX, Cheung PT, Yao KM, Chan BP. A 3D collagen microsphere culture system for GDNF-secreting HEK293 cells with enhanced protein productivity. Biomaterials. 2007; 28: 5369-5380.
32. Mendonca R, Prado J, Pereira C. Attachment, spreading and growth of VERO cells on microcarriers for the optimization of large scale cultures. Bioprocess Eng. 1999; 20: 565-571.
33. Wu S. Influence of hydrodynamic shear stress on microcarrier-attached cell growth: cell line dependency and surfactant protection. Bioprocess Eng. 1999; 21: 201-206.
34. Mollet M, Ma N, Zhao Y, Brodkey R, Taticek R, Chalmers JJ. Bioprocess equipment: characterization of energy dissipation rate and its potential to damage cells. Biotechnol Prog. 2004; 20: 1437-1448.
35. Croughan MS, Hamel JF, Wang DI. Hydrodynamic effects on animal cells grown in microcarrier cultures. Biotechnol Bioeng. 1987; 29: 130-141.
36. Ng YC, Berry JM, Butler M. Optimization of physical parameters for cell attachment and growth on macroporous microcarriers. Biotechnol Bioeng. 1996; 50: 627-635.