High-throughput 3-D cell-based proliferation and cytotoxicity assays for drug screening and bioprocess development

Journal of Biotechnology

Volumn 151, Issue 2, 2011, Pages 186-193

  Zhang, Xudong ^a,b   Yang, Shang Tian ^a  

^a Ohio State University   (United States)

^b KBI Biopharma Inc   (United States)

Author keywords

Cytotoxicity; Drug discovery; Green fluorescent protein; High throughput screening; Microplate; Three dimensional cell culture

Indexed keywords

DRUG DISCOVERY; GREEN FLUORESCENT PROTEIN; HIGH THROUGHPUT SCREENING; MICROPLATES; THREE DIMENSIONAL CELL CULTURE;

CYTOTOXICITY; DRUG PRODUCTS; FLUORESCENCE; POLYETHYLENE TEREPHTHALATES; PROTEINS; SIGNAL TO NOISE RATIO; THERMOPLASTICS; THREE DIMENSIONAL; THROUGHPUT;

CELL CULTURE;

FIBRONECTIN; FLUOROURACIL; GEMCITABINE; POLYETHYLENE TEREPHTHALATE;

ANIMAL CELL; ARTICLE; CANCER CELL; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; FLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; SIGNAL NOISE RATIO;

ANIMALS; BIOTECHNOLOGY; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; DRUG INDUSTRY; EMBRYONIC STEM CELLS; FIBRONECTINS; GREEN FLUORESCENT PROTEINS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; KINETICS; MICE;

BOVINAE; MURINAE;

EID: 78651488129     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2010.11.012     Document Type: Article

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