-
1
-
-
0028216544
-
Nuclear but not mitochondrial genome involvement in human age-related mitochondrial dysfunction. Functional integrity of mitochondrial DNA from aged subjects
-
Hayashi, J., Ohta, S., Kagawa, Y., Kondo, H., Kaneda, H., Yonekawa, H., Takai, D., and Miyabayashi, S. 1994. Nuclear but not mitochondrial genome involvement in human age-related mitochondrial dysfunction. Functional integrity of mitochondrial DNA from aged subjects. J. Biol. Chem. 269: 6878-6883.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 6878-6883
-
-
Hayashi, J.1
Ohta, S.2
Kagawa, Y.3
Kondo, H.4
Kaneda, H.5
Yonekawa, H.6
Takai, D.7
Miyabayashi, S.8
-
2
-
-
0030919442
-
Isolation of mitochondrial DNA-less mouse cell lines and their application for trapping mouse synaptosomal mitochondrial DNA with deletion mutations
-
Inoue, K., Ito, S., Takai, D., Soejima, A., Shisa, H., LePecq, J.B., Segal-Bendirdjian, E., Kagawa, Y., and Hayashi, J.I. 1997. Isolation of mitochondrial DNA-less mouse cell lines and their application for trapping mouse synaptosomal mitochondrial DNA with deletion mutations. J. Biol. Chem. 272: 15510-15515.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 15510-15515
-
-
Inoue, K.1
Ito, S.2
Takai, D.3
Soejima, A.4
Shisa, H.5
Lepecq, J.B.6
Segal-Bendirdjian, E.7
Kagawa, Y.8
Hayashi, J.I.9
-
3
-
-
43249112094
-
ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis
-
Ishikawa, K., Takenaga, K., Akimoto, M., Koshikawa, N., Yamaguchi, A., Imanishi, H., Nakada, K., Honma, Y., and Hayashi, J. 2008. ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis. Science. 320: 661-664.
-
(2008)
Science
, vol.320
, pp. 661-664
-
-
Ishikawa, K.1
Takenaga, K.2
Akimoto, M.3
Koshikawa, N.4
Yamaguchi, A.5
Imanishi, H.6
Nakada, K.7
Honma, Y.8
Hayashi, J.9
-
4
-
-
2642608683
-
Nuclear-recessive mutations of factors involved in mitochondrial translation are responsible for age-related respiration deficiency of human skin fibroblasts
-
Isobe, K., Ito, S., Hosaka, H., Iwamura, Y., Kondo, H., Kagawa, Y., and Hayashi, J.I. 1998. Nuclear-recessive mutations of factors involved in mitochondrial translation are responsible for age-related respiration deficiency of human skin fibroblasts. J. Biol. Chem. 273: 4601-4606.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 4601-4606
-
-
Isobe, K.1
Ito, S.2
Hosaka, H.3
Iwamura, Y.4
Kondo, H.5
Kagawa, Y.6
Hayashi, J.I.7
-
5
-
-
0033515075
-
Functional integrity of mitochondrial genomes in human platelets and autopsied brain tissues from elderly patients with Alzheimer's disease
-
Ito, S., Ohta, S., Nishimaki, K., Kagawa, Y., Soma, R., Kuno, S.Y., Komatsuzaki, Y., Mizusawa, H., and Hayashi, J. 1999. Functional integrity of mitochondrial genomes in human platelets and autopsied brain tissues from elderly patients with Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 96: 2099-2103.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 2099-2103
-
-
Ito, S.1
Ohta, S.2
Nishimaki, K.3
Kagawa, Y.4
Soma, R.5
Kuno, S.Y.6
Komatsuzaki, Y.7
Mizusawa, H.8
Hayashi, J.9
-
6
-
-
0042886929
-
The mitochondrial theory of aging: Dead or alive?
-
Jacobs, H.T. 2003. The mitochondrial theory of aging: dead or alive? Aging Cell. 2: 11-17.
-
(2003)
Aging Cell
, vol.2
, pp. 11-17
-
-
Jacobs, H.T.1
-
7
-
-
33644772616
-
Generation of trans-mitochondrial mice carrying homoplasmic mtdnas with a missense mutation in a structural gene using ES cells
-
Kasahara, A., Ishikawa, K., Yamaoka, M., Ito, M., Watanabe, N., Akimoto, M., Sato, A., Nakada, K., Endo, H., Suda, Y., Aizawa, S., and Hayashi, J. 2006. Generation of trans-mitochondrial mice carrying homoplasmic mtDNAs with a missense mutation in a structural gene using ES cells. Hum. Mol. Genet. 15: 871-881.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 871-881
-
-
Kasahara, A.1
Ishikawa, K.2
Yamaoka, M.3
Ito, M.4
Watanabe, N.5
Akimoto, M.6
Sato, A.7
Nakada, K.8
Endo, H.9
Suda, Y.10
Aizawa, S.11
Hayashi, J.12
-
8
-
-
22344456832
-
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
-
Kujoth, G.C., Hiona, A., Pugh, T.D., Someya, S., Panzer, K., Wohlgemuth, S.E., Hofer, T., Seo, A.Y., Sullivan, R., Jobling, W.A., Morrow, J.D., Van Remmen, H., Sedivy, J.M., Yamasoba, T., Tanokura, M., Weindruch, R., Leeuwenburgh, C., and Prolla, T.A. 2005. Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 309: 481-484.
-
(2005)
Science
, vol.309
, pp. 481-484
-
-
Kujoth, G.C.1
Hiona, A.2
Pugh, T.D.3
Someya, S.4
Panzer, K.5
Wohlgemuth, S.E.6
Hofer, T.7
Seo, A.Y.8
Sullivan, R.9
Jobling, W.A.10
Morrow, J.D.11
van Remmen, H.12
Sedivy, J.M.13
Yamasoba, T.14
Tanokura, M.15
Weindruch, R.16
Leeuwenburgh, C.17
Prolla, T.A.18
-
9
-
-
0029587469
-
Molecular genetic aspects of human mitochondrial disorders
-
Larsson, N.G. and Clayton, D.A. 1995. Molecular genetic aspects of human mitochondrial disorders. Annu. Rev. Genet. 29: 151-178.
-
(1995)
Annu. Rev. Genet.
, vol.29
, pp. 151-178
-
-
Larsson, N.G.1
Clayton, D.A.2
-
10
-
-
56649115977
-
Assembly of mitochondrial complex I and defects in disease
-
Lazarou, M., Thorburn, D.R., Ryan, M.T., and McKenzie, M. 2009. Assembly of mitochondrial complex I and defects in disease. Biochim. Biophys. Acta 1793: 78-88.
-
(2009)
Biochim. Biophys. Acta.
, vol.1793
, pp. 78-88
-
-
Lazarou, M.1
Thorburn, D.R.2
Ryan, M.T.3
McKenzie, M.4
-
11
-
-
0024814593
-
Defective pattern of mitochondrial respiratory enzymes in mitochondrial myopathy
-
Miyabayashi, S., Haginoya, K., Hanamizu, H., Iinuma, K., Narisawa, K., and Tada, K., 1989. Defective pattern of mitochondrial respiratory enzymes in mitochondrial myopathy. J. Inherit. Metab. Dis. 12: 373-377.
-
(1989)
J. Inherit. Metab. Dis.
, vol.12
, pp. 373-377
-
-
Miyabayashi, S.1
Haginoya, K.2
Hanamizu, H.3
Iinuma, K.4
Narisawa, K.5
Tada, K.6
-
12
-
-
0034855947
-
Unique mutations in mitochondrial DNA of senescence-accelerated mouse (SAM) strains
-
Mizutani, J., Chiba, T., Tanaka, M., Higuchi, K., and Mori, M. 2001. Unique mutations in mitochondrial DNA of senescence-accelerated mouse (SAM) strains. J. Hered. 92: 352-355.
-
(2001)
J. Hered.
, vol.92
, pp. 352-355
-
-
Mizutani, J.1
Chiba, T.2
Tanaka, M.3
Higuchi, K.4
Mori, M.5
-
13
-
-
33750428601
-
Differences in reactive oxygen species production explain the phenotypes associated with common mouse mitochondrial DNA variants
-
Moreno-Loshuertos, R., Acin-Perez, R., Fernandez-Silva, P., Movilla, N., Perez-Martos, A., Rodriguez de Cordoba, S., Gallardo, M.E., and Enriquez, J.A. 2006. Differences in reactive oxygen species production explain the phenotypes associated with common mouse mitochondrial DNA variants. Nat. Genet. 38: 1261-1268.
-
(2006)
Nat. Genet.
, vol.38
, pp. 1261-1268
-
-
Moreno-Loshuertos, R.1
Acin-Perez, R.2
Fernandez-Silva, P.3
Movilla, N.4
Perez-Martos, A.5
Rodriguez de Cordoba, S.6
Gallardo, M.E.7
Enriquez, J.A.8
-
14
-
-
0034881326
-
Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtdna
-
Nakada, K., Inoue, K., Ono, T., Isobe, K., Ogura, A., Goto, Y.I., Nonaka, I., and Hayashi, J.I. 2001. Inter-mitochondrial complementation: mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA. Nat. Med. 7: 934-940.
-
(2001)
Nat. Med.
, vol.7
, pp. 934-940
-
-
Nakada, K.1
Inoue, K.2
Ono, T.3
Isobe, K.4
Ogura, A.5
Goto, Y.I.6
Nonaka, I.7
Hayashi, J.I.8
-
15
-
-
0031974019
-
Mitochondrial dysfunction in the senescence accelerated mouse (SAM)
-
Nakahara, H., Kanno, T., Inai, Y., Utsumi, K., Hiramatsu, M., Mori, A., and Packer, L. 1998. Mitochondrial dysfunction in the senescence accelerated mouse (SAM). Free Radic. Biol. Med. 24: 85-92.
-
(1998)
Free Radic. Biol. Med.
, vol.24
, pp. 85-92
-
-
Nakahara, H.1
Kanno, T.2
Inai, Y.3
Utsumi, K.4
Hiramatsu, M.5
Mori, A.6
Packer, L.7
-
16
-
-
0036227594
-
Melatonin protects hepatic mitochondrial respiratory chain activity in senescence-accelerated mice
-
Okatani, Y., Wakatsuki, A., and Reiter, R.J. 2002. Melatonin protects hepatic mitochondrial respiratory chain activity in senescence-accelerated mice. J. Pineal Res. 32: 143-148.
-
(2002)
J. Pineal Res.
, vol.32
, pp. 143-148
-
-
Okatani, Y.1
Wakatsuki, A.2
Reiter, R.J.3
-
17
-
-
0034938453
-
Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria
-
Ono, T., Isobe, K., Nakada, K., and Hayashi, J.I. 2001. Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria. Nat. Genet. 28: 272-275.
-
(2001)
Nat. Genet.
, vol.28
, pp. 272-275
-
-
Ono, T.1
Isobe, K.2
Nakada, K.3
Hayashi, J.I.4
-
18
-
-
0033584845
-
Threshold effect and tissue specificity. Implication for mitochondrial cytopathies
-
Rossignol, R., Malgat, M., Mazat, J.P., and Letellier, T. 1999. Threshold effect and tissue specificity. Implication for mitochondrial cytopathies. J. Biol. Chem. 274: 33426-33432.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 33426-33432
-
-
Rossignol, R.1
Malgat, M.2
Mazat, J.P.3
Letellier, T.4
-
19
-
-
33745756805
-
Mitochondrial dynamics and aging: Mitochondrial interaction preventing individuals from expression of respiratory deficiency caused by mutant mtDNA
-
Sato, A., Nakada, K., and Hayashi, J. 2006. Mitochondrial dynamics and aging: mitochondrial interaction preventing individuals from expression of respiratory deficiency caused by mutant mtDNA. Biochim. Biophys. Acta 1763: 473-481.
-
(2006)
Biochim. Biophys. Acta.
, vol.1763
, pp. 473-481
-
-
Sato, A.1
Nakada, K.2
Hayashi, J.3
-
20
-
-
0030896787
-
Senescence-accelerated mouse (SAM): A novel murine model of senescence
-
Takeda, T., Hosokawa, M., and Higuchi, K. 1997. Senescence-accelerated mouse (SAM): a novel murine model of senescence. Exp. Gerontol. 32: 105-109.
-
(1997)
Exp. Gerontol
, vol.32
, pp. 105-109
-
-
Takeda, T.1
Hosokawa, M.2
Higuchi, K.3
-
21
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
Trifunovic, A., Wredenberg, A., Falkenberg, M., Spelbrink, J.N., Rovio, A.T., Bruder, C.E., Bohlooly-Y, M, Gidlof, S., Oldfors, A., Wibom, R., Tornell, J, Jacobs, H.T., and Larsson, N.G. 2004. Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 429: 417-423.
-
(2004)
Nature
, vol.429
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
Spelbrink, J.N.4
Rovio, A.T.5
Bruder, C.E.6
Bohlooly, Y.M.7
Gidlof, S.8
Oldfors, A.9
Wibom, R.10
Tornell, J.11
Jacobs, H.T.12
Larsson, N.G.13
-
22
-
-
0033525773
-
Mitochondrial diseases in man and mouse
-
Wallace, D.C. 1999. Mitochondrial diseases in man and mouse. Science 283: 1482-1488.
-
(1999)
Science
, vol.283
, pp. 1482-1488
-
-
Wallace, D.C.1
-
23
-
-
77956937212
-
Generation of trans-mitochondrial mito-mice by the introduction of a pathogenic G13997A mtdna from highly metastatic lung carcinoma cells
-
Yokota, M., Shitara, H., Hashizume, O., Ishikawa, K., Nakada, K., Ishii, R., Taya, C., Takenaga, K., Yonekawa, H., and Hayashi, J.I. 2010. Generation of trans-mitochondrial mito-mice by the introduction of a pathogenic G13997A mtDNA from highly metastatic lung carcinoma cells. FEBS Lett. 584: 3943-3948.
-
(2010)
FEBS Lett
, vol.584
, pp. 3943-3948
-
-
Yokota, M.1
Shitara, H.2
Hashizume, O.3
Ishikawa, K.4
Nakada, K.5
Ishii, R.6
Taya, C.7
Takenaga, K.8
Yonekawa, H.9
Hayashi, J.I.10
|