Reduced astrocytic contribution to the turnover of glutamate, glutamine, and GABA characterizes the latent phase in the kainate model of temporal lobe epilepsy

Journal of Cerebral Blood Flow and Metabolism

Volumn 31, Issue 8, 2011, Pages 1775-1786

  Alvestad, Silje ^a   Hammer, Janniche ^a,b   Qu, Hong ^a,b   Haberg, Asta ^a   Ottersen, Ole Petter ^b   Sonnewald, Ursula ^a  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

13C MRS; astrocytes; epileptogenesis; kainate; metabolism; neurons

Indexed keywords

4 AMINOBUTYRIC ACID; AMINOTRANSFERASE; BRANCHED CHAIN AMINO ACID; GLUTAMIC ACID; GLUTAMINE; KAINIC ACID; NEUROTRANSMITTER; AMINO ACID; BRANCHED CHAIN AMINO ACID TRANSAMINASE; BRANCHED-CHAIN-AMINO-ACID TRANSAMINASE; CARBON;

AMINO ACID SYNTHESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL METABOLISM; CONTROLLED STUDY; ENTORHINAL CORTEX; EPILEPTOGENESIS; HIPPOCAMPUS; LATENT PERIOD; MALE; NEOCORTEX; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; PYRIFORM CORTEX; RAT; TEMPORAL LOBE EPILEPSY; TRANSAMINATION; TURNOVER TIME; ANIMAL; ISOTOPE LABELING; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY;

AMINO ACIDS; ANIMALS; ASTROCYTES; CARBON ISOTOPES; EPILEPSY, TEMPORAL LOBE; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; GLUTAMINE; HIPPOCAMPUS; ISOTOPE LABELING; KAINIC ACID; MAGNETIC RESONANCE SPECTROSCOPY; RATS; TRANSAMINASES;

EID: 79960986558     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2011.36     Document Type: Article

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