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Volumn 8, Issue 4, 2011, Pages 483-491

Toward knowing the whole human: Next-generation sequencing for personalized medicine

Author keywords

genomic medicine; microarrays; next generation sequencing; personalized medicine; RNA sequencing

Indexed keywords

TRANSCRIPTOME;

EID: 79960963630     PISSN: 17410541     EISSN: 1744828X     Source Type: Journal    
DOI: 10.2217/pme.11.27     Document Type: Article
Times cited : (5)

References (43)
  • 1
    • 64949127696 scopus 로고    scopus 로고
    • Risk assessment and communication tools for genotype associations with multifactorial phenotypes: The concept of edge effect and cultivating an ethical bridge between omics innovations and society
    • Ozdemir V, Suarez-Kurtz G, Stenne R et al. Risk assessment and communication tools for genotype associations with multifactorial phenotypes: the concept of 'edge effect' and cultivating an ethical bridge between omics innovations and society. Omics 13(1), 43-61 (2009).
    • (2009) Omics , vol.13 , Issue.1 , pp. 43-61
    • Ozdemir, V.1    Suarez-Kurtz, G.2    Stenne, R.3
  • 2
    • 79951481957 scopus 로고    scopus 로고
    • Initial impact of the sequencing of the human genome
    • Lander ES. Initial impact of the sequencing of the human genome. Nature 470(7333), 187-197 (2011).
    • (2011) Nature , vol.470 , Issue.7333 , pp. 187-197
    • Lander, E.S.1
  • 3
    • 36049020719 scopus 로고    scopus 로고
    • Noncoding RNAs: Couplers of analog and digital information in nervous system function?
    • DOI 10.1016/j.tins.2007.10.002, PII S0166223607002676
    • St Laurent G 3rd, Wahlestedt C. Noncoding RNAs: couplers of analog and digital information in nervous system function? Trends Neurosci. 30(12), 612-621 (2007). (Pubitemid 350101854)
    • (2007) Trends in Neurosciences , vol.30 , Issue.12 , pp. 612-621
    • St. Laurent III, G.1    Wahlestedt, C.2
  • 6
    • 78651397147 scopus 로고    scopus 로고
    • Large non-coding RNAs: Missing links in cancer
    • Huarte M, Rinn JL. Large non-coding RNAs: missing links in cancer? Hum. Mol. Genet. 19(R2), R152-R161 (2010).
    • (2010) Hum. Mol. Genet. , vol.19 , Issue.R2
    • Huarte, M.1    Rinn, J.L.2
  • 7
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis function and decay
    • Krol J, Loedige I, Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 11(9), 597-610 (2010).
    • (2010) Nat. Rev. Genet. , vol.11 , Issue.9 , pp. 597-610
    • Krol, J.1    Loedige, I.2    Filipowicz, W.3
  • 8
    • 77952905505 scopus 로고    scopus 로고
    • Most dark matter transcripts are associated with known genes
    • van Bakel H, Nislow C, Blencowe BJ, Hughes TR. Most 'dark matter' transcripts are associated with known genes. PLoS Biol. 8(5), e1000371 (2010).
    • (2010) PLoS Biol. , vol.8 , Issue.5
    • Van Bakel, H.1    Nislow, C.2    Blencowe, B.J.3    Hughes, T.R.4
  • 9
    • 46249106990 scopus 로고    scopus 로고
    • Mapping and quantifying mammalian transcriptomes by RNA-Seq
    • DOI 10.1038/nmeth.1226, PII NMETH.1226
    • Mortazavi A, Williams BA, McCue K, Schaeffer L, Wold B. Mapping and quantifying mammalian transcriptomes by RNA-seq. Nat. Methods 5(7), 621-628 (2008). (Pubitemid 351911867)
    • (2008) Nature Methods , vol.5 , Issue.7 , pp. 621-628
    • Mortazavi, A.1    Williams, B.A.2    McCue, K.3    Schaeffer, L.4    Wold, B.5
  • 10
    • 33646087412 scopus 로고    scopus 로고
    • A highly standardized robust and cost-effective method for genome-wide transcriptome analysis of peripheral blood applicable to large-scale clinical trials
    • Debey S, Zander T, Brors B, Popov A, Eils R, Schultze JL. A highly standardized, robust, and cost-effective method for genome-wide transcriptome analysis of peripheral blood applicable to large-scale clinical trials. Genomics 87(5), 653-664 (2006).
    • (2006) Genomics , vol.87 , Issue.5 , pp. 653-664
    • Debey, S.1    Zander, T.2    Brors, B.3    Popov, A.4    Eils, R.5    Schultze, J.L.6
  • 14
    • 46249092601 scopus 로고    scopus 로고
    • Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites
    • DOI 10.1126/science.1155390
    • Sandberg R, Neilson JR, Sarma A, Sharp PA, Burge CB. Proliferating cells express mRNAs with shortened 3́ untranslated regions and fewer microRNA target sites. Science 320(5883), 1643-1647 (2008). (Pubitemid 351931255)
    • (2008) Science , vol.320 , Issue.5883 , pp. 1643-1647
    • Sandberg, R.1    Neilson, J.R.2    Sarma, A.3    Sharp, P.A.4    Burge, C.B.5
  • 16
    • 42449140726 scopus 로고    scopus 로고
    • Imprinted genes and human disease: An evolutionary perspective
    • Ubeda F, Wilkins JF. Imprinted genes and human disease: an evolutionary perspective. Adv. Exp. Med. Biol. 626, 101-115 (2008).
    • (2008) Adv. Exp. Med. Biol. , vol.626 , pp. 101-115
    • Ubeda, F.1    Wilkins, J.F.2
  • 17
    • 55549147191 scopus 로고    scopus 로고
    • Personal genomes: The case of the missing heritability
    • Maher B. Personal genomes: the case of the missing heritability. Nature 456(7218), 18-21 (2008).
    • (2008) Nature , vol.456 , Issue.7218 , pp. 18-21
    • Maher, B.1
  • 18
    • 38949176804 scopus 로고    scopus 로고
    • Genetics of age-related macular degeneration
    • Edwards AO. Genetics of age-related macular degeneration. Adv. Exp. Med. Biol. 613, 211-219 (2008).
    • (2008) Adv. Exp. Med. Biol. , vol.613 , pp. 211-219
    • Edwards, A.O.1
  • 20
    • 70349956433 scopus 로고    scopus 로고
    • Finding the missing heritability of complex diseases
    • Manolio TA, Collins FS, Cox NJ et al. Finding the missing heritability of complex diseases. Nature 461(7265), 747-753 (2009).
    • (2009) Nature , vol.461 , Issue.7265 , pp. 747-753
    • Manolio, T.A.1    Collins, F.S.2    Cox, N.J.3
  • 24
    • 77957947562 scopus 로고    scopus 로고
    • Hundreds of variants clustered in genomic loci and biological pathways affect human height
    • Lango Allen H, Estrada K, Lettre G et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 467(7317), 832-838 (2010).
    • (2010) Nature , vol.467 , Issue.7317 , pp. 832-838
    • Lango Allen, H.1    Estrada, K.2    Lettre, G.3
  • 25
    • 79551563242 scopus 로고    scopus 로고
    • Rare copy number deletions predict individual variation in intelligence
    • Yeo RA, Gangestad SW, Liu J, Calhoun VD, Hutchison KE. Rare copy number deletions predict individual variation in intelligence. PLoS ONE 6(1), e16339 (2011).
    • (2011) PLoS ONE , vol.6 , Issue.1
    • Yeo, R.A.1    Gangestad, S.W.2    Liu, J.3    Calhoun, V.D.4    Hutchison, K.E.5
  • 26
    • 84858997010 scopus 로고    scopus 로고
    • Rare structural variation of synapse and neurotransmission genes in autism
    • Epub ahead of print
    • Gai X, Xie HM, Perin JC et al. Rare structural variation of synapse and neurotransmission genes in autism. Mol. Psychiatry (2011) (Epub ahead of print).
    • (2011) Mol. Psychiatry
    • Gai, X.1    Xie, H.M.2    Perin, J.C.3
  • 27
    • 77952574849 scopus 로고    scopus 로고
    • Uncovering the roles of rare variants in common disease through whole-genome sequencing
    • Cirulli ET, Goldstein DB. Uncovering the roles of rare variants in common disease through whole-genome sequencing. Nat. Rev. Genet. 11(6), 415-425 (2010).
    • (2010) Nat. Rev. Genet. , vol.11 , Issue.6 , pp. 415-425
    • Cirulli, E.T.1    Goldstein, D.B.2
  • 28
    • 40049109536 scopus 로고    scopus 로고
    • Altered serotonin 2C receptor RNA splicing in suicide: Association with editing
    • DOI 10.1097/WNR.0b013e3282f556d2, PII 0000175620080212000023
    • Dracheva S, Chin B, Haroutunian V. Altered serotonin 2C receptor RNA splicing in suicide: association with editing. Neuroreport. 19(3), 379-382 (2008). (Pubitemid 351322981)
    • (2008) NeuroReport , vol.19 , Issue.3 , pp. 379-382
    • Dracheva, S.1    Chin, B.2    Haroutunian, V.3
  • 29
    • 68949169222 scopus 로고    scopus 로고
    • Editing of serotonin 2C receptor mRNA in the prefrontal cortex characterizes high-novelty locomotor response behavioral trait
    • Dracheva S, Lyddon R, Barley K, Marcus SM, Hurd YL, Byne WM. Editing of serotonin 2C receptor mRNA in the prefrontal cortex characterizes high-novelty locomotor response behavioral trait. Neuropsychopharmacology 34(10), 2237-2251 (2009).
    • (2009) Neuropsychopharmacology , vol.34 , Issue.10 , pp. 2237-2251
    • Dracheva, S.1    Lyddon, R.2    Barley, K.3    Marcus, S.M.4    Hurd, Y.L.5    Byne, W.M.6
  • 30
    • 78651507445 scopus 로고    scopus 로고
    • Adenosine deaminases acting on RNA RNA editing and interferon action
    • George CX, Gan Z, Liu Y, Samuel CE. Adenosine deaminases acting on RNA, RNA editing, and interferon action. J. Interferon Cytokine Res. 31(1), 99-117 (2011).
    • (2011) J. Interferon Cytokine Res. , vol.31 , Issue.1 , pp. 99-117
    • George, C.X.1    Gan, Z.2    Liu, Y.3    Samuel, C.E.4
  • 31
    • 33344477023 scopus 로고    scopus 로고
    • ADAR2-dependent RNA editing of AMPA receptor subunit GluR2 determines vulnerability of neurons in forebrain ischemia
    • DOI 10.1016/j.neuron.2006.01.025, PII S0896627306000791
    • Peng PL, Zhong X, Tu W et al. ADAR2- dependent RNA editing of AMPA receptor subunit GluR2 determines vulnerability of neurons in forebrain ischemia. Neuron 49(5), 719-733 (2006). (Pubitemid 43290131)
    • (2006) Neuron , vol.49 , Issue.5 , pp. 719-733
    • Peng, P.L.1    Zhong, X.2    Tu, W.3    Soundarapandian, M.M.4    Molner, P.5    Zhu, D.6    Lau, L.7    Liu, S.8    Liu, F.9    Lu, Y.10
  • 33
    • 77952967431 scopus 로고    scopus 로고
    • Direct detection of DNA methylation during single-molecule real-time sequencing
    • Flusberg BA, Webster DR, Lee JH et al. Direct detection of DNA methylation during single-molecule, real-time sequencing. Nat. Methods 7(6), 461-465 (2010).
    • (2010) Nat. Methods , vol.7 , Issue.6 , pp. 461-465
    • Flusberg, B.A.1    Webster, D.R.2    Lee, J.H.3
  • 34
    • 77449147610 scopus 로고    scopus 로고
    • FRT-seq: Amplification-free strand-specific transcriptome sequencing
    • Mamanova L, Andrews RM, James KD et al. FRT-seq: amplification-free, strand-specific transcriptome sequencing. Nat. Methods 7(2), 130-132 (2010).
    • (2010) Nat. Methods , vol.7 , Issue.2 , pp. 130-132
    • Mamanova, L.1    Andrews, R.M.2    James, K.D.3
  • 35
    • 72849144434 scopus 로고    scopus 로고
    • Sequencing technologies - the next generation
    • Metzker ML. Sequencing technologies - the next generation. Nat. Rev. Genet. 11(1), 31-46 (2010).
    • (2010) Nat. Rev. Genet. , vol.11 , Issue.1 , pp. 31-46
    • Metzker, M.L.1
  • 36
    • 77951799158 scopus 로고    scopus 로고
    • Analysis of genetic inheritance in a family quartet by whole-genome sequencing
    • Roach JC, Glusman G, Smit AFA et al. Analysis of genetic inheritance in a family quartet by whole-genome sequencing. Science 328(5978), 636-639 (2010).
    • (2010) Science , vol.328 , Issue.5978 , pp. 636-639
    • Roach, J.C.1    Glusman, G.2    Smit, A.F.A.3
  • 37
    • 77952538049 scopus 로고    scopus 로고
    • Quantitation in mass-spectrometry-based proteomics
    • Schulze WX, Usadel BR: Quantitation in mass-spectrometry-based proteomics. Annu. Rev. Plant Biol. 61(1), 491-516 (2010).
    • (2010) Annu. Rev. Plant Biol. , vol.61 , Issue.1 , pp. 491-516
    • Schulze, W.X.1    Usadel, B.R.2
  • 39
    • 34548499539 scopus 로고    scopus 로고
    • Meta-analysis of microarray results: Challenges, opportunities, and recommendations for standardization
    • DOI 10.1016/j.gene.2007.06.016, PII S0378111907003289
    • Cahan P, Rovegno F, Mooney D, Newman JC, St Laurent G 3rd, McCaffrey TA. Meta-analysis of microarray results: challenges, opportunities, and recommendations for standardization. Gene 401(1-2), 12-18 (2007). (Pubitemid 47379509)
    • (2007) Gene , vol.401 , Issue.1-2 , pp. 12-18
    • Cahan, P.1    Rovegno, F.2    Mooney, D.3    Newman, J.C.4    St. Laurent III, G.5    McCaffrey, T.A.6
  • 40
    • 78650621222 scopus 로고    scopus 로고
    • Toward the integration of personalized and systems medicine: Challenges opportunities and approaches
    • Yan Q. Toward the integration of personalized and systems medicine: challenges, opportunities and approaches. Pers. Med. 8(1), 1-4 (2011).
    • (2011) Pers. Med. , vol.8 , Issue.1 , pp. 1-4
    • Yan, Q.1
  • 41
    • 79951472909 scopus 로고    scopus 로고
    • Charting a course for genomic medicine from base pairs to bedside
    • Green ED, Guyer MS. Charting a course for genomic medicine from base pairs to bedside. Nature 470(7333), 204-213 (2011).
    • (2011) Nature , vol.470 , Issue.7333 , pp. 204-213
    • Green, E.D.1    Guyer, M.S.2
  • 42
    • 77951622284 scopus 로고    scopus 로고
    • Germs genomics and global public health: How can advances in genomic sciences be integrated into public health in the developing world to deal with infectious diseases
    • Pang T. Germs, genomics and global public health: how can advances in genomic sciences be integrated into public health in the developing world to deal with infectious diseases? Hugo J. 3(1-4), 5-9 (2009).
    • (2009) Hugo J. , vol.3 , Issue.1-4 , pp. 5-9
    • Pang, T.1
  • 43
    • 78650646491 scopus 로고    scopus 로고
    • Extending the reach of public health genomics: What should be the agenda for public health in an era of genome-based and personalized medicine
    • Burke W, Burton H, Hall AE et al. Extending the reach of public health genomics: what should be the agenda for public health in an era of genome-based and 'personalized' medicine? Genet. Med. 12(12), 785-791 (2010).
    • (2010) Genet. Med. , vol.12 , Issue.12 , pp. 785-791
    • Burke, W.1    Burton, H.2    Hall, A.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.